Patents
Patents for C07D 413 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms (64,687)
01/2006
01/17/2006CA2138930C Substituted benzenesulfonylureas and -thioureas, preparation processes and possible uses of pharmaceutical preparations based on these compounds
01/17/2006CA2118812C 5-ht4 receptor antagonists
01/12/2006WO2006004880A2 Substituted n-arylsulfonylheterocyclic amines as gamma-secretase inhibitors
01/12/2006WO2006004793A2 Hetero isonipecotic modulators of vanilloid vr1 receptor
01/12/2006WO2006004742A2 α, β-UNSATURATED ESTERS AND ACIDS BY STEREOSELECTIVE DEHYDRATION
01/12/2006WO2006003378A1 Azine-carboxamides as anti-cancer agent
01/12/2006WO2006003276A1 Substituted indazoles, compositions containing same, preparation and use
01/12/2006WO2006003096A1 Condensed thiophene derivatives and their use as cyclic glp-1 agonists
01/12/2006WO2005117908A3 Triheterocyclic compounds compositions, and methods for treating cancer or viral diseases
01/12/2006WO2005105817A3 Coupling process for generating reactive boron­ containing derivatives of n-substituted pyrrole-2­ carbonitriles to produce biaryls
01/12/2006WO2005105079A3 Novel imidazoles
01/12/2006WO2005103037A3 Selected cgrp antagonists, methods for the production thereof, and use thereof as medicaments
01/12/2006WO2005060959A8 Pyrazole derivatives and use thereof as orexin receptor antagonists
01/12/2006WO2005012270A3 Biaryl heterocyclic amines, amides, and sulfur-containing compounds and methods of making and using the same
01/12/2006US20060009472 Substituted imidazole derivatives
01/12/2006US20060009467 Novel gamma secretase inhibitors
01/12/2006US20060009461 Acetamides and benzamides that are useful in treating sexual dysfunction
01/12/2006US20060009455 especially blood coagulation factor XIa and plasma kallikrein; e.g. 4-aminomethyl-[2-phenyl-1-(4-phenyl-pyridin-2-yl)-ethyl]-trans cyclohexanecarboxamide; anticoagulant, antiinflammatory agent;
01/12/2006US20060009453 Protein kinase modulators and method of use
01/12/2006US20060009446 New compounds
01/12/2006DE102004031100A1 Anthranilamide Anthranilamides
01/12/2006DE102004030099A1 Gesättigte und ungesättigte 3-Pyridyl-benzocycloalkylmethyl-amine als Serotonin- und/oder Noradrenalin-Reuptake-Hemmer und/oder µ-Opioidrezeptor-Modulatoren Saturated and unsaturated 3-pyridyl-benzocycloalkylmethyl-amines as serotonin and / or norepinephrine reuptake inhibitor and / or μ-opioid receptor modulators
01/12/2006CA2572075A1 Hetero isonipecotic modulators of vanilloid vr1 receptor
01/12/2006CA2570318A1 Biaryl derivatives
01/12/2006CA2570183A1 Substituted n-arylsulfonylheterocyclic amines as gamma-secretase inhibitors
01/12/2006CA2570169A1 Azine-carboxamides as anti-cancer agent
01/12/2006CA2567744A1 Substituted indazoles, compositions containing same, preparation and use
01/11/2006EP1614683A1 Indazole compounds and pharmaceutical compositions for inhibiting protein kinases, and methods for their use
01/11/2006EP1614680A2 Process for preparing 2-iminopyrrolidine derivatives
01/11/2006EP1614678A2 Sulfur substituted sulfonylaminocarboxylic acid N-heteroarylamides, their preparation, their use and pharmaceutical preparations comprising them
01/11/2006EP1613634A1 Indole acetamides as inhibitors of the hepatitis c virus ns5b polymerase
01/11/2006EP1613624A2 Novel compounds having an antibacterial activity
01/11/2006EP1613623A1 Novel oxazole derivatives, their manufacture and use as pharmaceutical agents
01/11/2006EP1613618A2 BENZIMIDAZOLE DERIVATIVES AND THEIR USE FOR MODULATING THE GABA- sb A /sb RECEPTOR COMPLEX
01/11/2006EP1613613A2 Cxcr4 chemokine receptor binding compounds
01/11/2006EP1613368A2 Carboxamide spirohydantoin cgrp receptor antagonists
01/11/2006EP1613322A2 Aminoquinoline compounds
01/11/2006EP1613319A2 Substituted phenyl acetamides and their use as protease inhibitors
01/11/2006EP1613318A2 Compounds and their use to treat diabetes and related disorders
01/11/2006EP1613304A1 Dpp-iv inhibitors
01/11/2006EP1613156A1 N-phenyl- " (4-pyridyl)- azinyl!amine derivatives as plant protection agents
01/11/2006EP1442035B1 Process for the preparation of 4- (8-chloro-5, 6-dihydro-11h-benzo-[5,6]-cyclohepta-[1,2-b]-pyridin-11-ylidene)-1-piperidinecarboxylic acid ethyl ester (loratadine)
01/11/2006EP1421082B1 piperidinyl-morpholinyl derivatives as modulators of chemokine receptor activity
01/11/2006CN1720236A 4-substituted benzimidazoles and their use as inhibitors of gastric secretion
01/11/2006CN1720225A N-arylsulfonyl-3-substituted indoles having serotonin receptor affinity, process for their preparation and pharmaceutical composition containing them
01/11/2006CN1720047A PgD2 receptor antagonists for the treatment of inflammatory diseases
01/11/2006CN1235898C Cyclohexenondioxothio chromanoyl derivatives
01/11/2006CN1235887C Preparation method of xazolyl alcohol derivatives
01/10/2006US6984735 Reacting a dihalaromatic compound with sulfoxide
01/10/2006US6984653 useful as a growth factor receptor tyrosine kinase HER2 (Human epidermal growth factor receptor-2) inhibitor; for treating cancer
01/10/2006US6984651 Piperidine amides as modulators of chemokine receptor activity
01/10/2006US6984649 Pyridine derivatives
01/10/2006US6984648 TNF (tumor necrosis factor); for treating conditions such as rheumatoid and osteoarthritis, corneal, epidermal or gastric ulceration; tumor metastasis or invasion; periodontal disease and bone disease
01/10/2006CA2383332C Benzisoxazolyl-, pyridoisoxazolyl- and benzthienyl-phenoxy derivatives useful as d4 antagonists
01/10/2006CA2223918C Pyrrole derivatives and medicinal composition
01/05/2006WO2006002284A1 Ubiquitin ligase inhibitors
01/05/2006WO2006002236A1 N- (1- (1-benzyl -4-phenyl-1h-imidazol-2-yl) -2,2-dymethylpropyl) benzamide derivatives and related compounds as kinesin spindle protein (ksp) inhibitors for the treatment of cancer
01/05/2006WO2006001750A1 Imidazole variants as modulators of gaba receptor for the treatment of gi disorders
01/05/2006WO2006000759A1 Substituted diketopiperazines as oxytocin antagonists
01/05/2006WO2006000371A2 Pyrimidine derivatives as 11beta-hsd1 inhibitors
01/05/2006WO2006000353A1 Method for producing 4-(benzimidazolylmethylamino)-benzamidines
01/05/2006WO2005099709A3 Bicyclic heterocycles useful as serine protease inhibitors
01/05/2006WO2005095364A8 Phenoxyacetic acid derivative and medicine containing the same
01/05/2006WO2005094329A8 Compouns, compositions, processes of making, and methods of use related to inhibiting macrophage migration inhibitory factor
01/05/2006WO2005085194A3 Indole-2-carboxylic acid hydrazides as glycogen phosphorylase inhibitors
01/05/2006WO2005059107A3 Chemokine receptor binding compounds
01/05/2006WO2004080976A8 Phthalazinone derivatives
01/05/2006WO2002046150A3 Compounds which mimic the chemical and biological properties of discodermolide
01/05/2006US20060004195 Alpha,beta-unsaturated esters and acids by stereoselective dehydration
01/05/2006US20060004084 (3Z)-3-(2,3-dihydro-1H-inden-1-ylidene)-1,3-dihydro-2H-indol-2-ones as kinase inhibitors
01/05/2006US20060004069 Agent for preventing or treating neuropathy
01/05/2006US20060004064 Condensation of substituted diaminobenzene with 2-[4-(1,2,4-oxadiazol-5-on-3-yl)phenylamino]acetic acid; then hydrogenation; carbonylation with an alkylhalogen formate, in the presence of hexyl chloroformate; 4-(benzimidazol-2-ylmethylamino)benzamidine; prevention of deep vein thrombosis
01/05/2006US20060004063 Inhibitors of HCV NS5B polymerase
01/05/2006US20060004062 Compounds for inhibiting insulin secretion and methods related thereto
01/05/2006US20060004044 3-glyoxylamideindoles for treating cancer
01/05/2006US20060004033 Imidazolo-5-yl-2-anilino-pyrimidines as agents for the inhibition of the cell proliferation
01/05/2006US20060004030 Asthma, antiallergens; rheumatoid arthritis and atherosclerosis; anticarcinogenic agents; 2-(Benzylthio)-6-{[(1R)-2-hydroxy-1-methylethyl]amino}-4-pyrimidinol
01/05/2006US20060004024 Reacting 2,4-difluorophenyl (4-piperidinyl) methanone oxime hydrochloride and 3-(2-haloethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one in an aqueous alkali solution: high yeild when alkali hydroxide concentration is in the range of 20 to 40%
01/05/2006US20060004017 Quinazoline derivatives as angiogenesis inhibitors
01/05/2006US20060004013 Cinnamide compound
01/05/2006US20060004004 Novel gamma secretase inhibitors
01/05/2006US20060004001 Specific binding is extremely high; low toxicity; high degree of activity; 2-(5-m-Tolyl-thiazol-2-yl )-7,8-dihydro-6H-quinolin-5-one, acute and/or chronic neurological disorders
01/05/2006US20060004000 N-aryl-5-substituted-3-yl-1H-indazole-3-carboxamides; amidation of the 1-protected-1H-indazole-3-carboxylic acid, deblocking; hypotensive agents
01/05/2006US20060003999 reduction of 4-methoxy-5-(3-morpholinopropoxy)-2-nitrobenzonitrile to give 2-amino-4-methoxy-5-(3-morpholinopropoxy)benzonitrile, hydration of intermediated to form 2-amino-4-methoxy-5-(3-morpholinopropoxy)benzamide; cyclization
01/05/2006US20060003998 2-(2-Methoxy-phenyl)-1-morpholin-2-yl-1-phenyl-ethanol hydrochloride; selective inhibitors of the reuptake of norepinephrine; in membrane cells of central nervous system; anxiolitic agent, cognition activator, psycological disorder
01/05/2006US20060003993 Benzotriazepnes as gastrin and cholecystokinin receptor ligands
01/05/2006US20060003978 beta-secretase inhibitors; to reduce A beta peptide formation; to reduce amyloid beta deposits or plaques; 12-[2-(3-Ethyl-benzylamino)-1-hydroxy-ethyl]-16-fluoro-2-oxa-8,11-diaza-bicyclo[12.3.1]octadeca-1(17),14(18),15-triene-7,10-dione
01/05/2006US20060003970 Novel combi-molecules having EGFR and DNA targeting properties
01/05/2006DE102004028973A1 Substituierte Tetrahydro-2H-isochinolin-1-on-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Medikament Substituted tetrahydro-2H-isoquinolin-1-one derivatives, to processes for their preparation and their use as a medicament
01/05/2006DE102004027821A1 Benzimidazole, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel Benzimidazoles, process for their preparation and their use as medicaments
01/05/2006DE102004024453A1 Neue langwirksame Bronchodilatoren zur Behandlung von Atemwegserkrankungen New long-acting bronchodilators for the treatment of respiratory disorders
01/05/2006CA2810655A1 Modulators of atp-binding cassette transporters
01/05/2006CA2571949A1 Modulators of atp-binding cassette transporters
01/05/2006CA2571712A1 Novel indazole carboxamides and their use
01/05/2006CA2571087A1 Novel piperidine derivates as modulators of chemokine receptor ccr5
01/05/2006CA2571002A1 N-(1-(1-benzyl-4-phenyl-1h-imidazol-2-yl)-2,2-dimethylpropyl)benzamide derivatives and related compounds as kinesin spindle protein (ksp) inhibitors for the treatment of cancer
01/05/2006CA2570673A1 Compounds and methods for treating dyslipidemia
01/05/2006CA2570619A1 Imidazole variants as modulators of gaba receptor for the treatment of gi disorders
01/05/2006CA2570499A1 Method for producing 4-(benzimidazolylmethylamino)-benzamidines
01/04/2006EP1612208A2 N-phenylarylsulfonamide compound, pharmaceutical composition comprising the compound as active ingredient, synthetic intermediate for the compound and process for its preparation