Patents
Patents for C07D 405 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom (69,397)
05/2003
05/28/2003CN1420881A Beta-amino acid derivs. as inhibitors of matrix metalloproteases and TNF-alpha
05/28/2003CN1420879A Substd. pyridines and pyridazines with angiogenesis inhibiting activity
05/28/2003CN1420869A Modulators of dopamine neurotransmission
05/28/2003CN1420114A 2,3-disubstd. -4(3H)-quinazolones
05/28/2003CN1109680C Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
05/28/2003CN1109675C Arylpyrimidine derivs.
05/27/2003US6569889 Anticarcinogenic agents
05/27/2003US6569888 Such as ethyl-N-(dichlorobenzyl)-4-(3-hydroxypropylthio) indole-2-carboxylate; for treatment of arthritis
05/27/2003US6569882 Viricides; enzyme inhibitors
05/27/2003US6569881 Substituted benzimidazole, the production thereof and the use thereof as means against parasitic protozoa
05/27/2003US6569860 Alkoxycarbonylamino-heteroaryl carboxylic acid derivatives useful for treating the disorders of the urinary tract, pain, inflammation, respiratory states, edema formation, hypotensive vascular diseases, pain and allergies
05/27/2003US6569855 Particularly zinc metalloprotease activity for treatment of variety of maladies involving inflammation and/or tissue integrity
05/27/2003CA2268847C Substituted oximes derivatives useful as neurokinin antagonists
05/22/2003WO2003042699A1 Tagged microparticle compositions and methods
05/22/2003WO2003042234A2 Non-peptide somatostatin receptor ligands
05/22/2003WO2003042205A1 Piperidine derivatives and their use as modulators of chemokine receptor activity (especially ccr5)
05/22/2003WO2003042191A1 Benzamide and heteroarylamide as p2x7 receptor antagonists
05/22/2003WO2003042187A1 Serin protease inhibitors
05/22/2003WO2003042181A1 4,4-difluoro-1,2,3,4-tetrahydro-5h-1-benzazepine derivatives or salts thereof
05/22/2003WO2003042178A1 Novel piperidine derivatives as modulators of chemokine receptors
05/22/2003WO2003042176A1 Azabicyclo compound, matrix metalloprotease inhibitor, and skin preparation
05/22/2003WO2003042174A1 Cannabinoid receptor ligands
05/22/2003WO2003042164A1 Aryl aniline beta-2 adrenergic receptor agonists
05/22/2003WO2003041715A1 Substituted 1,4-benzodiazepines and uses thereof for the treatment of cancer
05/22/2003WO2003041711A1 Piperazine bis-amide derivatives and their use as antagonists of the orexin receptor
05/22/2003WO2003041708A1 Benzimidazoles useful as protein kinase inhibitors
05/22/2003WO2003041644A2 Method to treat cystic fibrosis
05/22/2003WO2003022280A3 3-glyoxlylamideindoles for treating cancer
05/22/2003WO2003007883A3 Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents
05/22/2003WO2002100327A3 Substituted 1-benzazepines and derivatives thereof
05/22/2003WO2002096362A3 Method for treating fibrotic diseases or other indications vi
05/22/2003WO2002030924A9 Quinazoline derivatives with anti-tumour activity
05/22/2003US20030097004 3,4-Di-substituted cyclobutene-1,2-diones as CXC chemokine receptor antagonists
05/22/2003US20030096858 The parent drug compound is modified by forming one or more of predetermined chemical arrangement within parent drug structure for programming specific course and rate of metabolism for drug that leads to inactive nontoxic metabolite
05/22/2003US20030096841 For treatment of cancers, heart disease, such as congestive heart failure, osteoporosis, genetic, inflammatory, allergic, and autoimmune diseases
05/22/2003US20030096827 Heterocyclic amine derivatives; for treating an inflammatory or immune disease, a cardiovascular disease, or a neurodegenerative condition
05/22/2003US20030096826 Inhibitors of interleukin-1 beta converting enzyme and other cysteine proteases in the ICE family
05/22/2003US20030096825 Antiviral activity; treatment of HIV and AIDS
05/22/2003US20030096820 Nitrogen containing heterobicycles as factor Xa inhibitors
05/22/2003US20030096819 Aryl and heteroaryl substituted fused pyrrole anti-inflammatory agents
05/22/2003US20030096817 Inhibiting mammalian protein kinases (p38) with (2,6-difluoro-phenyl)-(5-iodo-pyridin-2-yl)amine for treatment of cardiovascular disorders
05/22/2003US20030096796 N-cyanomethyl amides which are cysteine protease inhibitors; use treating diseases associated with activity of cathepsins B, K, L or S such as autoimmune disorders, allergic disorder, allogeneic immune response, cardiovascular disorders
05/22/2003US20030096765 Aromatic esters; cytotoxic agents; antitumor agents
05/22/2003US20030096737 Caspase inhibitors and uses thereof
05/22/2003US20030096381 Production of polyketides
05/22/2003US20030096117 Base structure is a chromene(3,2-a)fluorene ring containing spiro-fused rings; photochromic lenses; large fading rate, less color when deteriorated, and excellent light resistance in the photochromic properties
05/22/2003US20030095992 Altering a drug's distribution, metabolism and elimination properties, especially by modifying with aralkyl ester moieties to increase rate of metabolism to inactive and nontoxic metabolites when exposure is halted; surgery, riots
05/22/2003US20030095958 Inhibiting beta amyloid converting enzyme responsible for A beta peptide cleavage to treat Alzheimer's Disease, Down's Syndrome, etc.
05/22/2003CA2466962A1 Aryl aniline beta-2 adrenergic receptor agonists
05/22/2003CA2466665A1 Method to treat cystic fibrosis
05/22/2003CA2466440A1 Cannabinoid receptor ligands
05/22/2003CA2466055A1 Substituted 1,4-benzodiazepines and uses thereof for the treatment of cancer
05/22/2003CA2464419A1 Benzimidazoles useful as protein kinase inhibitors
05/22/2003CA2464347A1 Piperidine derivatives and their use as modulators of chemokine receptor activity (especially ccr5)
05/22/2003CA2464069A1 4,4-difluoro-1,2,3,4-tetrahydro-5h-1-benzazepine derivative or salt thereof
05/21/2003EP1312622A1 Process for the preparation of linear or branched 1,4-cis polybutadiene
05/21/2003EP1311503A1 Chromenone derivatives and their use for treating diseases in conjunction with 5-hta1 receptors and/or dopamine d2 receptors
05/21/2003EP1311502A1 Bicyclic heteroaromatic derivatives for the treatment of immune and inflammatory disorders
05/21/2003EP1311473A2 Novel compounds inhibiting factor xa activity
05/21/2003EP1311295A2 Use of 5ht4 receptor antagonists in the manufacture of a medicament for the prophylaxis or treatment of atrial fibrillation
05/21/2003EP1311272A1 Novel methods using cholinesterase inhibitors
05/21/2003EP1023268B1 Isoquinolines as urokinase inhibitors
05/21/2003EP0874827B1 Quinoline derivatives as nk3 antagonists
05/21/2003CN1419553A Prodigiosin-derivatives as neoplastic and anti-viral agents
05/21/2003CN1419548A 4-amino-5-cyano-2-anilino-pyrimidine derivatives and their use as inhbitors of cell-cycle kinases
05/21/2003CN1419545A 3-cyanoquinolines, 3-cyano-1,6-naphthyridines, and 3-cyano-1,7-naphthyridines as protein kinase inhibitors
05/21/2003CN1419542A Heterocyclic acylsulfimides, a method for their production, agents containing the same and their use as pesticides 403
05/21/2003CN1419541A Pharmaceutically active pyrrolidine derivatives as BAX inhibitors
05/21/2003CN1419450A Nitrite salts of antimicrobial agents
05/21/2003CN1418966A Resoldution method for racemic compound of nucleoside enantiomorph
05/21/2003CN1418882A Substituted sulfonic N-[(amino imino methyl) phenyl alkyl]-acacycloamide compound
05/21/2003CN1418872A 1,4-pentadiene-3-ketone compound containing halogenoindyl, and method for preparing same and medicinal use thereof
05/21/2003CN1109108C Method for resolution of a racemic mixture of nucleoside enantioners
05/21/2003CN1109030C Processes for preparing intermediate product used in method of diastereoselective syntheses of nucleosides
05/21/2003CN1109029C oxygenic heterocyclic compounds
05/21/2003CN1109026C Sidechain-beering taxanes like compounds
05/21/2003CN1109022C Arylalkanoyl pyridazines derivatives, its preparation method, medicine comprising samd and use thereof
05/20/2003US6566566 Dimerization of a C6-12 olefin mixture in which the hexene isomer fraction has less than 30% by weight of linear isomers in the presence of a nickel catalyst; derivatization to give primary alcohols, and optional subsequent alkoxylation
05/20/2003US6566518 Trifluoromethylpyri(mi)dine carboxamides
05/20/2003US6566509 Compound for use as bactericide
05/20/2003US6566468 Provide polymeric resin products having low polydispersity; polymers produced contain a glycidyl or alkylcarbonyl group attached to the starting molecule of the radical chain reaction.
05/20/2003US6566385 And the prenylation of the oncogene protein Ras; peptidomimetic macrocyclic compounds
05/20/2003US6566376 Diphenyl-piperidine derivative
05/20/2003US6566373 For therapy of osteoporosis, periodontitis, and arthritis
05/20/2003US6566372 Useful in female hormone replacement therapy and as modulators of fertility; therapy of dysfunctional uterine bleeding, dysmenorrhea, endometriosis, leiomyomas (uterine fibroids), hot flashes, mood disorders, meningiomas, cancer
05/20/2003US6566364 Linear or cyclic ureas
05/20/2003US6566070 Detecting preferential protein biosynthesis; label nucleotide sequences, mix with translation system, incubate, detct signal from protein
05/20/2003CA2223016C Protein tyrosine kinase aryl and heteroaryl quinazoline compounds having selective inhibition of her-2 autophosphorylation properties
05/20/2003CA2156177C Quinoline derivatives as thromboxane a2 and leukotriene d4 antagonists
05/20/2003CA2144962C 1-(2-oxo-acetyl)-piperidine-2-carboxylic acid derivatives as multi-drug-resistant cancer cell sensitizers
05/20/2003CA2110693C Amino acid derivative anticonvulsant
05/15/2003WO2003040382A1 Process for producing optically active chroman derivative and intermediate
05/15/2003WO2003040160A1 Rhodium and iridium complexes
05/15/2003WO2003040147A1 Azabicyclic-substituted-heteroaryl compounds for the treatment of disease__________________________________________________________________________________________________________________________
05/15/2003WO2003040131A1 Aminopyrimidines and pyridines
05/15/2003WO2003040125A1 Piperazine derivatives having sst1 antagonistic activity
05/15/2003WO2003040109A2 Quinazoline derivatives as antitumor agents
05/15/2003WO2003040108A1 Quinazoline derivatives as antitumor agents
05/15/2003WO2003040107A1 Imidazole-4-carboxamide derivatives, preparation and use thereof for treatment of obesity
05/15/2003WO2003040106A1 Preparation and use of substituted imidazoles