| Patents for C07D 403 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group (62,587) |
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| 05/08/2008 | US20080108660 such as 4-{[4-({[(3-isopropyl-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)carbonyl]amino}methyl)piperidin-1-yl]methyl}tetrahydro-2H-pyran-4-carboxylic acid; serotonin receptor agonist; antidepressant, anxiolytic agent, analgesic, cognition activator; less toxicity, good absorption, and metabolic stability |
| 05/08/2008 | US20080108653 Tripeptidyl peptidase inhibitors |
| 05/08/2008 | US20080108638 antiallergen; not direct way to change nature of immunological response to allergen; G-protein-coupled "chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2)" antagonist for prostaglandin PGD2, that mediates PGD2-dependent migration of blood Th2 cells; ; asthma, rhinitis, COPD |
| 05/08/2008 | US20080108634 Novel phenylalanine derivatives |
| 05/08/2008 | US20080108630 Substituted triazoles as modulators of ppar and methods of their preparation |
| 05/08/2008 | US20080108629 Heterocyclic Derivatives for the Treatment of Diseases Mediated by Stearoyl-Coa Desaturase Enzymes |
| 05/08/2008 | US20080108628 Treatment of diseases or disorders mediated by T lymphocytes and/or PKC; may be coadminstered with an immunosuppressant, immunomodulatory, anti-inflammatory, antiproliferative or anti-diabetic drug |
| 05/08/2008 | US20080108626 (5-amino-1-phenyl-1H-pyrazole)-(3-Amino-N-isoxazol-3-yl-4-methyl)-benzamide; p38 mitogen-activated protein kinase inhibitor; reduced levels of TNF- alpha expression; antiinfammatory agent: rheumatoid arthritis, psoriasis, multiple sclerosis, endotoxin shock, osteoporosis, Alzheimer's disease |
| 05/08/2008 | US20080108625 Substituted Triazole Derivatives as Oxytocin Antagonists |
| 05/08/2008 | US20080108620 N-(4-{(1S)-1-[3-(3,5-DICHLOROPHENYL)-5-QUINOLIN-3-YL-1H-PYRAZOL-1-YL]ETHYL}BENZOYL)- beta -ALANINE; glucagon receptor antagonists; antidiabetic agent; insulin resistance and its complications, including coronary heart disease, stroke, hypertension, nephropathy, neuropathy, retinopathy; atherosclerosis |
| 05/08/2008 | US20080108616 as serine/threonine, fusion, and tyrosine kinase receptors as nerve and fibroblast growth factor; abnormal activation of immune and nervous systems; antiproliferative; lung; 4-(3-Trifluoromethyl-phenylamino)-pyrrolo[2,3-d]pyrimidine-7-carboxylic acid [3-(4-morpholin-4-yl-phenylcarbamoyl)-phenyl]-amide |
| 05/08/2008 | US20080108614 Substituted 2-Amino-Quinazolin-4-Cn Compounds for Use in the Treatment of Cns Disorders, Pain, Stroke, Addiction and Epilepsy, their Preparation and Use as Intermediates |
| 05/08/2008 | US20080108608 Pyrimidines With Tie2 (Tek) Activity |
| 05/08/2008 | US20080108601 anticancer agents; catalytic hydrogenation |
| 05/08/2008 | DE102006049618A1 Triazine und Ihre Verwendung als Metalloproteinase-Inhibitoren Triazines and their use as metalloproteinase inhibitors |
| 05/08/2008 | CA2668491A1 Novel cannabinoid receptor ligands, pharmaceutical compositions containing them, and processes for their preparation |
| 05/08/2008 | CA2668454A1 Substituted 2-imidazoles |
| 05/08/2008 | CA2667920A1 Process for preparing indol-5-oxy-quinazoline derivatives and intermediates |
| 05/08/2008 | CA2667685A1 Indazole derivatives useful as l-cpt1 inhibitors |
| 05/07/2008 | EP1918288A1 A novel and improved process for the preparation of Irbesartan, an angiotensin-II receptor antagonist for the treatment of hypertension |
| 05/07/2008 | EP1918284A1 Hydrazinopyrimidines as cysteine protease inhibitors |
| 05/07/2008 | EP1918279A2 1-(4-piperidinyl)-1,3-dihydro-2h-benzoxazole-2-one derivatives and related compounds as nociceptin analogs and opioid receptor like receptor (ORL1) ligands for the treatment of pain |
| 05/07/2008 | EP1918277A2 Azulene compounds |
| 05/07/2008 | EP1917323A1 Novel materials for organic electroluminescent devices |
| 05/07/2008 | EP1917262A1 Piperidine and piperazine derivatives as p2x3 antagonists |
| 05/07/2008 | EP1917259A2 Pyrazine kinase inhibitors |
| 05/07/2008 | EP1917258A2 Pyrimidinyl-pyrazole inhibitors of aurora kinases |
| 05/07/2008 | EP1917252A1 Pyrazine derivatives and use as pi3k inhibitors |
| 05/07/2008 | EP1917247A1 4,5-dihydr0-1h-pyrazole derivatives, their preparation and use as medicaments |
| 05/07/2008 | EP1917246A1 Benzoquinazoline derivatives and their use in treating bone disorders |
| 05/07/2008 | EP1916896A2 Non-steroidal antiandrogens |
| 05/07/2008 | EP1761519B1 Indole derivatives as histamine receptor antagonists |
| 05/07/2008 | EP1601670B1 Arylvinylazacycloalkane compounds and methods of preparation and use thereof |
| 05/07/2008 | EP1575963B1 Anti-angiogenetic therapeutic agents |
| 05/07/2008 | EP1480951B1 Synthesis of indole thiazole compounds as ligands for the ah receptor |
| 05/07/2008 | EP1390347B1 Pyrrolidine ester derivatives with oxytocin modulating activity |
| 05/07/2008 | EP1299381B1 Substituted quinazoline derivatives and their use as inhibitors |
| 05/07/2008 | CN101175748A N,n-substituted 3-aminopyrrolidine compounds useful as monoamines reuptake inhibitors |
| 05/07/2008 | CN101175729A 1-phenyl-3-piperazine-pyrazoles and pesticidal compositions of matter thereof |
| 05/07/2008 | CN101175722A Azetidine derivatives as ccr-3 receptor antagonists |
| 05/07/2008 | CN101172983A Substituted phenylacetic acids |
| 05/07/2008 | CN100386314C Pharmaceutical compositions containing azetidine derivatives novel azetidine derivatives and preparation thereof |
| 05/06/2008 | US7368563 Treatment of atherosclerosis, hypercholesterolemia diabetes, obesity, stroke, alzheimer's, demyelination and lowering plasma levels of sterols |
| 05/06/2008 | US7368562 Treatment of atherosclerosis, hypercholesterolemia diabetes, obesity, stroke, demyelination and lowering plasma levels of sterols |
| 05/06/2008 | US7368470 Such as (4-propyl-phenyl)-{3-[1-(4-trifluoromethyl-benzyl)-1H-indol-3-yl]-pyrrolidin-1-yl}-methanone; treatment of pain and/or depression |
| 05/06/2008 | US7368467 Calcium channel modulators 2-(alkyl or (hetero)arylalkylthio)-imidazoles and S-oxides thereof; angina, hypertension, congestive heart failure, myocardial ischemia, arrhythmia, diabetes, urinary incontinence, stroke, pain, brain injury, or neuronal disorders |
| 05/06/2008 | US7368465 Metalloproteinase inhibitors |
| 05/06/2008 | US7368455 2-(4-fluorophenyl)-3-[2-(2-methoxy-1-methylethylamino)pyrimidin-4-yl]-6,7-dihydro-5H-pyrazolo[1,2-a]pyrazol-1-one; cytokines (interleukin-1, 6, 8 and Tumor Necrosis Factor- alpha) inhibitor; antiinflammatory and antiarthritic agents; osteoporosis, rheumatic diseases; antidiabetic |
| 05/06/2008 | US7368453 Quinazolinone compounds with reduced bioaccumulation |
| 05/06/2008 | US7368451 N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-(4-{4-[3-(1H-tetrazol-5-yl)propoxy]phenyl}butyl)guanidine hydrochloride; hydrates mucosal surfaces; are absorbed less rapidly, thus have a prolonged pharmacodynamic half-life; skin and respiratory disorders, vision deffects |
| 05/06/2008 | US7368450 Sodium channel blockers |
| 05/06/2008 | US7368447 N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-(4-{4-[3-(1H-tetrazol-5-yl)propoxy]phenyl}butyl)guanidine hydrochloride; hydrates mucosal surfaces; are absorbed less rapidly, thus have a prolonged pharmacodynamic half-life; skin and respiratory disorders, vision deffects |
| 05/06/2008 | US7368224 Photopolymerizable composition |
| 05/02/2008 | WO2008051547A1 Fused bicyclic derivatives of 2,4-diaminopyrimidine as alk and c-met inhibitors |
| 05/02/2008 | WO2008051541A2 Process for preparing anhydrous aripirazole type i |
| 05/02/2008 | WO2008051532A1 2-[1-phenyl-5-hydroxy or methoxy-4alpha-methyl-hexahydroclopenta[f]indazol-5-yl]ethyl phenyl derivatives as glucocorticoid receptor ligands |
| 05/02/2008 | WO2008051440A1 Crystal modifications -3- (1h-ind0l-3-yl) -4- [2- (4-methyl-piperazin-1-yl) -quinazolin-4-yl] -pyrrole-2, 5-d ione |
| 05/02/2008 | WO2008051047A1 Aminopyrazole derivatives, process for the preparation thereof, and composition for preventing or treating ischemic diseases containing the same |
| 05/02/2008 | WO2008050117A1 Benzoyl amino heterocyclyl compounds as glucokinase (glk) activators |
| 05/02/2008 | WO2008049994A1 New fluorene derivatives, compositions containing the same and use thereof as inhibitors of the protein chaperone hsp 90 |
| 05/02/2008 | WO2008049950A1 Novel polynitrogenated systems as anti-hiv agents |
| 05/02/2008 | WO2008049585A1 Pyridazine derivatives |
| 05/02/2008 | WO2008019971A3 Arylpiperazine derivatives and uses thereof |
| 05/02/2008 | WO2008019030A8 Modified azole compounds as antiinfective agents |
| 05/02/2008 | WO2008011611A3 Compounds and compositions as itpkb inhibitors |
| 05/02/2008 | WO2008002676A3 Biaryl compositions and methods for modulating a kinase cascade |
| 05/02/2008 | WO2008001188A8 An improved process for the preparation of substantially pure aripiprazole |
| 05/02/2008 | WO2007150010A3 Cyclopropyl amine derivatives as histamin h3 receptor modulators |
| 05/02/2008 | WO2007081569A3 Cetp inhibitors |
| 05/02/2008 | CA2669111A1 Fused bicyclic derivatives of 2,4-diaminopyrimidine as alk and c-met inhibitors |
| 05/02/2008 | CA2667551A1 Novel polynitrogenated systems as anti-hiv agents |
| 05/02/2008 | CA2667435A1 Chemical compounds |
| 05/02/2008 | CA2667316A1 Benzoyl amino heterocyclyl compounds as glucokinase (glk) activators |
| 05/02/2008 | CA2667235A1 Pyridazine derivatives |
| 05/02/2008 | CA2667007A1 2-[1-phenyl-5-hydroxy or methoxy-4alpha-methyl-hexahydrocyclopenta[f]indazol-5-yl]ethyl phenyl derivatives as glucocorticoid receptor ligands |
| 05/02/2008 | CA2666965A1 Crystal modifications of -3-(1h-indol-3-yl)-4-[2-(4-methyl-piperazin-1-yl)-quinazolin-4-yl]-pyrrole-2,5-dione |
| 05/02/2008 | CA2664115A1 New fluorene derivatives, compositions containing the same and use thereof as inhibitors of the protein chaperone hsp 90 |
| 05/02/2008 | CA2644929A1 Somatostatin agonists |
| 05/01/2008 | US20080103307 chroman compound, the method of its preparation and pharmaceutical applications. The compound are represented by formula (I) and its pharmaceutical salt, where in :x is for O or S; n is for 2, 3 or 4; R1 is 6-situ or 7-situ halogen, C1-4alkyl, C1-4alkyoxyl, benzyloxy, acylamino; R2 is nitrogen-containin |
| 05/01/2008 | US20080103305 Process for the preparation of imatinib |
| 05/01/2008 | US20080103300 Preparation of quinoxaline compounds |
| 05/01/2008 | US20080103187 Reaction product of N-methylpyrrole, N-methylimidazole, 4-aminobutyric acid and B-alanine that can be folded into a U-shaped conformation at the gamma -aminobutyrate unit in a minor groove of a double helix region; conjugates with fluorescein isothiocyanate; antiproliferative agents; restenosis |
| 05/01/2008 | US20080103182 N-[1-(4-Difluoromethoxy-benzyl)-1H-indazol-3-yl]-terephthalamic acid;liver carnitine palmitoyl transferase 1 (L-CPT1) nhibitor; antidiabetic and hypotensive agent; obesity, insulin resistance, hyperglycemia; reduce liver beta -oxidation, consequently inhibit gluconeogenesis |
| 05/01/2008 | US20080103181 4-trifluoromethyl-N-(3,3a,4,4a,5,5a,6,6a-octahydro-1,3-dioxo-4,6-ethenocycloprop[f]isoindol-2(1H)-yl)-benzamide; viricide; with other active agents: interferons, ribavirin, immunoglobulins, immunomodulators, anti-inflammatory agents, antibiotics, antivirals or anti-infectious |
| 05/01/2008 | US20080103150 and geranylgeranyltransferase inhibitor; 3-chloromethyl-4-cyanobenzyl-5 methyl triazole; antitumor agents; prevent membrane attachment of protein p21ras and block aberrant growth of ras-transformed tumors; capable to inhibit prenylation of Ras proteins, both at enzymatic and cellular level |
| 05/01/2008 | US20080103148 Preventing ventilator induced pneumonia; utilizing compounds having longer half life on mucosal surfaces |
| 05/01/2008 | US20080103142 c-Jun N-terminal kinase and cyclin-dependent kinase inhibitor; (4-benzotriazol-1-yl-5-chloro-pyrimidin-2-yl)-cyclohexyl-amine; antiinflammatory and anticarcinogenic agent; autoimmune and neurodegenerative disorders; rheumatoid arthritis, asthma, type II diabetes, Alzheimer's and Parkinson's diseases |
| 05/01/2008 | US20080103129 Heterocyclic derived metalloprotease inhibitors |
| 05/01/2008 | US20080102026 Hypoxia-selective, weakly basic 2-nitroimidazole delivery agents and methods of use thereof |
| 05/01/2008 | US20080099111 Water-based synthesis of poly(tetrazoles) |
| 04/30/2008 | EP1916246A2 An improved process for the preparation of olmesartan medoxomil |
| 04/30/2008 | EP1916245A1 Indole derivative having pgd2 receptor antagonist activity |
| 04/30/2008 | EP1916240A1 Pyridazine derivatives |
| 04/30/2008 | EP1915369A1 Novel substituted 1,2,3-t ii azolylmethyl-benzothiophene or -indole and their use as leukotiiene biosynthesis inhibitors |
| 04/30/2008 | EP1915367A1 Heteroarylcarbamoylbenzene derivatives for the treatment of diabetes |
| 04/30/2008 | EP1915366A2 Piperazine derivative renin inhibitors |
| 04/30/2008 | EP1915351A1 Quinazoline derivatives useful in cancer treatment |
| 04/30/2008 | EP1915350A1 Amide derivatives |
| 04/30/2008 | EP1915348A1 Azinyl-3-sulfonylindazole derivatives as 5-hydroxytryptamine-6 ligands |
| 04/30/2008 | EP1915345A1 Fluoro substituted 2-oxo azepan derivatives |