Patents
Patents for C07D 401 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom (107,979)
09/2004
09/10/2004WO2004075823A2 Novel benzimidazole and imidazopyridine derivatives and use thereof as a medicament
09/10/2004WO2004060362A3 COMPOSITIONS AND METHODS FOR INHIBITING TGF-β
09/10/2004WO2004060263A3 Magnesium salt of imidazole derivative
09/10/2004WO2004052847A3 Tricyclic steroid hormone nuclear receptor modulators
09/10/2004WO2004050643A3 Non-nucleoside reverse transcriptase inhibitors
09/10/2004WO2004047769A3 Benzimidazoles and analogs thereof as antibacterials
09/10/2004WO2004041776A3 SULFONYLAMINOVALEROLAC TAMS AND DERIVATIVES THEREOF AS FACTOR Xa INHIBITORS
09/10/2004WO2004034985A3 Chemical compounds
09/10/2004WO2004022523A3 1, 3-diamino-2-hydroxypropane prodrug derivatives
09/10/2004WO2004014352A3 Methods for treating carbonic anhydrase mediated disorders
09/10/2004WO2003087092A3 Inhibitors of serine proteases, particularly hepatitis c virus ns3 - ns4 protease
09/10/2004WO2003079984A3 Substituted tetracycline compounds
09/10/2004WO2003061652A8 3-(imidazolyl)-2-alkoxypropanoic acids as tafia inhibitors
09/10/2004CA2517391A1 Ethynyl derivatives serving as factor xa inhibitors
09/10/2004CA2517334A1 Water compatible sterically hindered alkoxyamines and hydroxy substituted alkoxyamines
09/10/2004CA2517256A1 Aminoheteroaryl compounds as protein kinase inhibitors
09/10/2004CA2516684A1 Selective non-steroidal glucocorticoid receptor modulators
09/10/2004CA2516660A1 Novel benzimidazole and imidazopyridine derivatives and use thereof as a medicament
09/10/2004CA2516465A1 Chemical process for the preparation of intermediates to obtain n-formyl hydroxylamine compounds
09/10/2004CA2516418A1 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-alkoxy-3-quinolinecarbonitriles for the treatment of ischemic injury
09/10/2004CA2516407A1 Heteroarylcarbamoylbenzene derivatives
09/10/2004CA2515963A1 Phenyl- and pyridylpiperidine-derivatives as modulators of glucose metabolism
09/10/2004CA2512886A1 Ligands that modulate lxr-type receptors
09/09/2004US20040176605 Compounds as antumor agents or immunosuppressants
09/09/2004US20040176603 Substituted nitrogen-containing heterobicycles, the preparation thereof and their use as pharmaceutical compositions
09/09/2004US20040176602 3-Cyanoquinolines,3-cyano-1,6-naphthyridines, and 3-cyano-1,7-naphthyridines as protein kinase inhibitors
09/09/2004US20040176594 Drugs that inhibit phosphorylation kinases as an antigrowth or antiproliferation agent
09/09/2004US20040176593 Cyclic diamine compounds used as drugs and chemical intermediates
09/09/2004US20040176591 Novel synthesis and crystallization of peperazine ring-containing compounds
09/09/2004US20040176443 Capsaicin receptor ligands
09/09/2004US20040176434 Pyrazoloanthrone derivatives as Jun N-terminal kinase inhibitors; diabetes; obesity
09/09/2004US20040176433 treatment of tumor necrosis factor mediated disorders; asthma; inflammatory bowel disease; arthritis
09/09/2004US20040176428 treatment of Type 2 diabetes mellitus, obesity and lipid disorders; coadministration with HMG CoA reductase inhibitors
09/09/2004US20040176419 particularly chronic obstructive pulmonary disease (COPD), asthma or a related pulmonary disease such as chronic bronchitis or allergic rhinitis
09/09/2004US20040176413 5HT2 antagonists; glaucoma; antipsychotic; thrombolytic; drug addiciton therapy; Raynaud's phenomenon
09/09/2004US20040176411 especially useful for treating asthma and/or rhinitis; example compound N-[[[2-[4-(3,4-dichlorophenoxy)-1-piperidinyl]ethyl]amino]carbonyl]-4-methyl-benzenesulfonamide
09/09/2004US20040176410 Analgesics and antiallodynia agents, e.g., 1-[2-(4-cyanophenyl)ethyl]-4-(4-nitrophenoxymethyl)piperidin-4-ol and analogues; oral administration to treat neuropahic pain; side effect reduction; highly efficient
09/09/2004US20040176389 Piperazine oxime dervatives having nk-1 receptor antagonistic activity
09/09/2004US20040176388 example compound: cis-1-[(2-chloro-3-trifluoromethylphenyl)acetyl]-6-(3,4,5-trimethylpiperazin-1-yl)indole; treatment of CNS and other disorders
09/09/2004US20040176386 Compounds
09/09/2004US20040176385 treating cancer by inhibiting phosphotidylinositol 3-kinase; in combination with other known agents to modulate cellular proliferation
09/09/2004US20040176384 inhibit Tissue factor expression and vascular permeability factor expression in cancer cells and in vascular endothelial cells in the tumor microenvironment; low toxicity to normal vascular endothelial cells
09/09/2004US20040176382 treatment of inflammation, proliferative diseases, and certain cardiovascular disorders as well as Alzheimer's disease;
09/09/2004US20040176379 agonist effect from one or more of a somatostatin subtype receptor; diabetes mellitus, hyperlipidemia, insulin insensitivity, Syndrome X; inhibiting the proliferation of helicobacter pylori
09/09/2004US20040176377 inhibitors of glycogen synthase kinase-3 beta; treatment of diabetes or neurodegenerative diseases such as Alzheimer's disease; 6-(2-butylamino-pyrimidin-4-yl)-3-oxo-2,3-dihydro-pyridazine-4-carboxylic acid (3-pyridin-3-yl-propyl)-amide, as example
09/09/2004US20040176375 Benzene acetamide compounds useful as serine protease inhibitors
09/09/2004US20040176364 Aryl substituted thiazinidinones and the use thereof
09/09/2004US20040176363 N-Acylpiperazine derivatives; cardiovascular disorders; anticoagulants
09/09/2004US20040176362 Matrix metalloproteinase inhibitors, treatment of tumor necrosis factor mediated diseases; autoimmune and neurodegenerative disorders; anticarcinogenic and antiinflammatory agents
09/09/2004US20040176361 2H-Isoquinolin-1-one derivatives as poly/ADP-ribose/ polymerase inhibitors
09/09/2004US20040176358 Compositions and methods relating to novel compounds and targets thereof
09/09/2004US20040176356 4-(Hydroxyalkyl-)-piperazinyl(thio)acetamide derivatives for treatment of cardiovascular disorders; antiarrhythmia agents; intermittent claudication, angina, congestive heart failure and myocardial infarction
09/09/2004US20040176355 Melanin-concentrating hormone antagonists for eating disorder and diabetes treatment
09/09/2004US20040176348 Arylvinylazacycloalkane compounds and methods of preparation and use thereof
09/09/2004US20040176326 N-substituted 3-hydroxy-4-pyridinones and pharmaceuticals containing thereof
09/09/2004US20040176325 P38 MAP kinase inhibitors comprising indazole derivatives; antiinflammatory and antiproliferative agents; autoimmune, bone, and neurodegenerative disorders; viricides, infections
09/09/2004US20040176252 Well tolerated; intracellularly increasing cAMP; antiasthmatics, antiinflammatories: regulation of eosinophiles activation and degranulation
09/09/2004US20040173224 Nicotine salts having improved taste, process for their preparation and their use
09/09/2004DE10308907A1 Ethynylderivate Ethynylderivate
09/09/2004DE10306250A1 Substituierte N-Arylheterozyklen, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel Substituted N-Arylheterozyklen, processes for their preparation and their use as medicaments
09/08/2004EP1454902A1 N- (substituted five-membered di-or triaza diunsaturated ring)carbonyl guanidine derivateives for the treatment of ischemia
09/08/2004EP1454901A1 Piperazine compounds and pharmaceutical compositions containing them.
09/08/2004EP1454898A1 Novel phenylalanine derivative
09/08/2004EP1453825A1 N-ureido-piperidines as antagonists viii for ccr-3 receptor
09/08/2004EP1453824A1 New generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
09/08/2004EP1453823A1 2-guanidino-4-heterocyclylquinazolines
09/08/2004EP1453811A2 Peroxisome proliferator activated receptor agonists
09/08/2004EP1453810A1 Substituted 4-phenyltetrahydroisoquinolines, method for the production thereof, the use thereof as medicaments, in addition to a medicament containing same
09/08/2004EP1453806A1 Aminotetralin derivatives as muscarinic receptor antagonist
09/08/2004EP1453805A1 4-piperidinyl alkylamine derivatives as muscarinic receptor antagonists
09/08/2004EP1453803A2 Tetrahydrocarbozole derivatives as ligands for g-protein coupled receptors (gpcr)
09/08/2004EP1453801A1 Substituted 2-amino-cycloalkanecarboxamides and their use as cysteine protease inhibitors
09/08/2004EP1453800A2 Protein kinase inhibitors
09/08/2004EP1453789A2 N,n'-substituted-1,3-diamino-2-hydroxypropane derivatives
09/08/2004EP1453516A2 Novel tri-substituted pyrimidines, method for production and use thereof as medicament
09/08/2004EP1453515A2 Method to treat cystic fibrosis
09/08/2004EP1453513A1 Use of fpt inhibitors and at least two antineoplastic agents in the treatment of cancer
09/08/2004EP1453512A1 Acetylene derivatives having mglur 5 antagonistic activity
09/08/2004EP1453501A1 N- aryl-n'-arylcycloalkyl-urea derivatives as mch antagonists for the treatment of obesity
09/08/2004EP1345603A4 (halo-benzo carbonyl)heterocyclo fused phenyl p38 kinase inhibiting agents
09/08/2004EP1335913B1 A process for the preparation of pantoprazole and intermediates therefor
09/08/2004EP1289972B1 Serine protease inhibitors
09/08/2004EP1289950B1 Serine protease inhibitors
09/08/2004EP1194416B1 Halopyrimidines
09/08/2004EP1165505B1 Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds
09/08/2004EP1122243B1 Novel imidazoles with anti-inflammatory activity
09/08/2004EP1084119B1 Aromatic amine derivatives as pharmaceutical agents
09/08/2004EP1047678B1 1-substituted-1-aminomethyl-cycloalkane derivatives (=gabapentin analogues), their preparation and their use in the treatment of neurological disorders
09/08/2004EP0993456B1 2-substituted 4,5-diaryl imidazoles
09/08/2004EP0824524B1 Alpha-substituted pyrimidine-thioalkyl and alkylether compounds as inhibitors of viral reverse transcriptase
09/08/2004EP0785782B1 Use of disubstituted acetylenes bearing heteroaromatic and heterobicyclic groups having retinoid-like activity
09/08/2004EP0623126B1 Imidazole derivatives and their use as cytokine inhibitors
09/08/2004CN1527829A Pyrazole derivatives as HIV reverse transcriptase inhibitors
09/08/2004CN1527828A 4-(penyl-piperidin-4-ylidene-methyl)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
09/08/2004CN1527827A Therapeutic heterocyclic compounds
09/08/2004CN1527818A 4-(phenyl-(piperidin-4-yl)-amino)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
09/08/2004CN1527816A New indole derivatives with 5-HT6 receptor affinity
09/08/2004CN1527710A Substituted pyrazinones, pyridines and pyrimidines as corticotropin releasing factor ligands
09/08/2004CN1527709A Therapeutic combinations for cardiovascular and inflammatory indications
09/08/2004CN1165546C New derivative of erythromycin, its preparation method and medicinal application