Patents
Patents for C07D 271 - Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms (7,144)
06/2008
06/10/2008US7384963 2′-Methyl-5-(1,3,4-oxadiazol-2-yl)1, 1′-biphenyl-4-carboxaide derivatives and their use as p38 kinase
06/10/2008US7384929 N-aryl azaspiroalkene and azaspiroalkane compounds and methods of preparation and use thereof
06/04/2008CN101190917A 3,4-dihydro-3-methyl-4-oxomidazo[5,1-d]-1,2,3,5-tetrazine-8-formic acid benzenesulfonyl furoxan esters compound, preparation method and use thereof
06/03/2008US7381821 Reacting 4-(alpha-(p-chlorophenyl)benzyl)-1-leaving group-alkylpiperazine with protected 1-hydroxy-1-(4-(p-hydroxyphenyl)-3-butynyl)urea to form 1-(4-(p-(4-(alpha-(p-chlorophenyl)benzyl)-1-piperazin-1-ylalkyl)phenyl)-3-butynyl)-1-hydroxyurea; preparation of intermediates
05/2008
05/29/2008WO2008064320A2 Hydrindane analogs having sphingosine 1-phosphate receptor agonist activity
05/29/2008WO2008064315A1 Tetralin analogs having sphingosine 1-phosphate agonist activity
05/29/2008US20080125433 Method of treating hair loss using thyromimetic compounds
05/29/2008CA2669104A1 Hydrindane analogs having sphingosine 1-phosphate receptor agonist activity
05/29/2008CA2669102A1 Tetralin analogs having sphingosine 1-phosphate agonist activity
05/28/2008CN100390135C Novel derivatives of dicarboxylic acid having pharmaceutical properties
05/27/2008US7378529 Heteroaryl, heterocyclic and aryl compounds which inhibit leukocyte adhesion mediated by VLA-4
05/27/2008US7378409 Substituted cycloalkylamine derivatives as modulators of chemokine receptor activity
05/22/2008WO2008059128A1 Phenylic derivatives and use thereof as drugs
05/22/2008US20080119486 Benzoyl-piperazine derivatives
05/21/2008EP1482924B1 Cathepsin cysteine protease inhibitors
05/21/2008CN101184739A Polycyclic oxadiazoles or isoxazoles and their use as S1P receptor ligands
05/20/2008US7375134 N1-(1-cyanocyclopropyl)-4-fluoro-N2-{(1S)-2,2,2-trifluoro-1-[4'-(methylsulfonyl)-1,1'-biphenyl-4-yl]ethyl}-L-leucinamide; osteoporosis and other bone loss disorders
05/15/2008WO2008058178A1 N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase
05/15/2008WO2008057775A2 Heterocyclic amide compounds useful as kinase inhibitors
05/15/2008US20080114002 3-[2-(3-Cyanophenoxy)-4-(trifluoromethyl)phenyl]propanoic acid;prostaglandin D2 inhibitor, orphan receptor CRTH2 antagonist; antiinflammatory, analgesic, antipyretic; respiratory system disorders: asthma and rhinitis; coupling amino/thio-phenyl derivatives with ester followed by hydrolysis to acid
05/14/2008EP1919464A1 Oxadiazole compounds as urokinase inhibitors
05/14/2008EP1446375B1 Dihalogenpropene compounds, method for the production thereof, agents containing said compounds and the use thereof as pest control agents
05/08/2008WO2008039431A3 Crystalline forms of 3-[5-(2-fhjorophenyl)-[1,2,4]oxadiazol-3-yl]-benzoic acid
05/08/2008US20080108811 Aromatic Amine Derivative and Organic Electroluminescent Device Using Same
05/07/2008EP1917323A1 Novel materials for organic electroluminescent devices
05/07/2008CN101175736A Compound, composition, phase difference plate, elliptically polarizing plate and liquid crystal display device
05/07/2008CN101172983A Substituted phenylacetic acids
05/06/2008US7368479 Alpha-sulfonylamino-acetonitriles
05/02/2008WO2008050200A1 Oxadiazole compounds as calcium channel antagonists
04/2008
04/29/2008US7365196 Sulphonamido-substituted bridged bicycloalkyl derivatives
04/29/2008US7365074 Pyridazine, pyrimidine and pyrazine ethyne compounds
04/29/2008US7365068 Hepatitis C virus infections; -(3-cyclopropyl-4-(pentyloxy)phenyl)-3-nicotinoylthiourea;methyl 2-oxo-2-(5-((3-(4-(pentyloxy)-3-(trifluoromethyl)phenyl)thioureido)carbonyl)pyridin-2-ylamino)acetate
04/29/2008US7364670 Liquid crystalline compound, liquid crystalline composition and retardation film
04/24/2008US20080096874 Oxadiazole Derivative as Dgat Inhibitors
04/23/2008EP1914225A1 Salt molten at room temperature and display device
04/23/2008EP1912971A2 Di-substituted oxadiazoles as cxc-chemokine receptor ligands
04/23/2008EP1912958A1 Substituted malononitrile compounds for combating animal pests
04/17/2008US20080090854 Cxcr2 inhibitors
04/17/2008US20080090840 Heterocyclic GPR40 Modulators
04/16/2008CN101163690A 苯并噻吩异羟肟酸衍生物 Benzothiophene hydroxamic acid derivatives
04/15/2008US7358265 Oxa-and thiadiazoles and their use as metalloproteinase inhibitors
04/15/2008CA2410303C Beta-amino acid nitrile derivatives
04/10/2008US20080086009 Reacting a alkyl nitrile selected from acetonitrile, propionitrile, or butyronitrile with acetone or acetophenone in presence of ferric nitrate to produce 3-acetyl-5-methyl or ethyl or other alkyl-1,2,4-oxadiazole derivative or a 3-benzoyl-5- ethyl or methyl or other alkyl-l 1,2,4-oxadiazole derivatives
04/10/2008US20080085894 Alpha-(n-sulfonamido)acetamide derivatives as beta-amyloid inhibitors
04/09/2008EP1907383A1 Gpcr agonists
04/09/2008EP1907382A1 Nitrocatechol derivatives as comt inhibitors
04/09/2008CN101157661A Method for producing molsidomine
04/09/2008CN100379415C Hetero biaryl derivatives as matrix metalloproteinase inhibitors
04/03/2008WO2008039431A2 Crystalline forms of 3-[5-(2-fhjorophenyl)-[1,2,4]oxadiazol-3-yl]-benzoic acid
04/03/2008WO2008039023A1 Heteroaryl-pyrazole derivatives as cannabinoid cb1 receptor antagonists
04/03/2008WO2008037476A1 Oxadiazole derivatives with anti-inflammatory and immunosuppressive properties
04/03/2008US20080081812 and inverse agonist; 2-(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazol-3-yl)-5-(pyridin-4-yl)-1,3,4-oxadiazole; obesity and obesity-related metabolic disorders
04/03/2008CA2664268A1 Diaryl oxadiazol derivatives
04/03/2008CA2663574A1 Crystalline forms of 3-[5-(2-fluorophenyl)-[1,2,4]oxadiazol-3-yl]-benzoic acid
04/02/2008CN100378086C Novel piperazine derivatives and their use as synthesis intermediates
04/02/2008CN100378085C Preparation process of 5-alkyl-1,3,4-oxidazole ketone
04/02/2008CN100378084C 2,5-diaryl substituting group-1,3,4-oxidazole derivative, its synthesis and use
04/01/2008US7351825 4-[5-((1S,2R)-1-Carboxy-2-phenyl-cyclopropylsulfamoyl)-thiophen-2-yl]-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester; aggrecanase and matrix metalloproteinase (with zinc in the catalytic active center) (MMP) inhibitor; antiarthritic agent: osteoarthritis, rheumatoid arthritis
03/2008
03/27/2008WO2008035239A1 Phenyl derivatives and their use as immunomodulators
03/27/2008CA2662673A1 Phenyl derivatives and their use as immunomodulators
03/26/2008EP1901731A1 Niacin receptor agonists, compositions containing such compounds and methods of treatment
03/26/2008EP0971878B1 Amine compounds, their production and use as amyloid-beta production inhibitors
03/25/2008US7348440 Mitotic kinesin inhibitors
03/25/2008US7348345 Nonnucleoside reverse transcriptase inhibitors
03/20/2008WO2008016692A3 Chemical compounds
03/20/2008US20080070957 p-(2-alkoxy-2-acylethyl)biphenyl compounds; 1-[4'-(2-ethoxy-3-morpholin-4-yl-3-oxopropyl)biphenyl-3-yl]-3-heptyl-1-methylurea; human or veterinary medicine: dermatology, cardiovascular diseases, immune diseases,; lipid metabolism diseases; Peroxisome Proliferator-Activated Receptor modulator
03/19/2008EP1149091B1 4-(heterocyclylsulfonamido)-5-methoxy-6-(2-methoxyphenoxy)-2-phenyl- or pyridylpyrimidines as endothelin receptor antagonists
03/18/2008US7345095 Alpha, beta -peptide inhibitors; Alzheimer's disease; 2-(4-Chloro-benzenesulfonylamino)-3-phenyl-propionic acid methyl ester
03/13/2008WO2008030570A1 Processes for the preparation of 1,2,4-oxadiazole benzoic acids
03/13/2008US20080064879 Compound ,Composition And Thin Film
03/13/2008US20080064728 Heterocyclic Compounds Useful as Dpp-Iv Inhibitors
03/13/2008CA2842625A1 Processes for the preparation of 1,2,4-oxadiazole benzoic acids
03/13/2008CA2662749A1 Processes for the preparation of 1,2,4-oxadiazole benzoic acids
03/06/2008US20080058335 Pain, inflammatory or immune disorders, neurological disorders, cancers of the immune system, respiratory disorders, cardiovascular disorders, neuroprotection; e.g. 5-chloro-N-[(2Z)-5-(1-hydroxy-1-methylethyl)-3-[((cis)-3-methoxycyclobutyl)methyl]-4-methyl-1,3-thiazol-2(3H)-ylidene]-2-methoxybenzamide
03/06/2008US20080058314 Novel dicarboxylic acid derivatives with pharmaceutical properties
03/05/2008EP1893592A1 Oxadiazole derivatives as dgat inhibitors
03/05/2008EP1893591A1 POLYCYCLIC OXADIAZOLES OR I SOXAZOLES AND THEIR USE AS SlP RECEPTOR LIGANDS
03/05/2008EP1718967A4 METHODS OF DETECTING Lp-PLA2 ACTIVITY
02/2008
02/28/2008WO2008023783A1 Amine compound
02/28/2008WO2008023157A1 Nitrogen containing heterocyclic compounds useful as m3-receptor modulators
02/28/2008WO2007016136A3 Organic nitric oxide enhancing salts of cyclooxygenase-2 selective inhibitors, compositons and methods of use
02/28/2008WO2007016095A3 Cyclooxygenase-2 selective inhibitor compounds comprising nitric oxide enhancing groups, compositions and methods of use
02/28/2008US20080051441 Aryl Sulphonamide Modulators
02/28/2008CA2660524A1 Compounds for treating proliferative disorders
02/27/2008EP1891000A1 Sphingolipids
02/27/2008EP1399423B9 Anthranilic acid amides with a heteroarylsulfonyl side chain, method for the production thereof, use thereof as a medicament or diagnostic agent and pharmaceutical preparations containing said compounds
02/26/2008CA2322195C Novel diphenyl-substituted 5-ring-heterocycles, method for producing them and their use as medicaments
02/21/2008WO2006134317A8 Oxadiazole derivatives as dgat inhibitors
02/21/2008US20080045571 Additional heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
02/20/2008EP1888512A2 Chemical compounds
02/20/2008CN101128413A Substituted oxyarenes
02/19/2008US7332514 Dibenzylamine compound and medicinal use thereof
02/14/2008US20080039510 (1,5-diphenyl-1h-pyrazol-3-yl)oxadiazole derivatives, preparation method thereof and use of same in therapeutics
02/13/2008EP1513796B1 Phenyloxyalkanoic acid derivatives as hppar activators
02/13/2008CN101124201A Parp抑制剂 Parp inhibitors
02/12/2008US7329756 Process for the manufacture of Isradipine
02/07/2008WO2008016692A2 Chemical compounds
02/07/2008WO2008016139A1 Fluorescent oleamide derivative and use thereof
02/07/2008US20080033022 Inhibitors of c-Jun N-terminal kinases (JNK)
02/07/2008CA2659473A1 Chemical compounds
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