Patents
Patents for C07D 243 - Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms (5,961)
06/1990
06/27/1990EP0375658A1 Quinoline derivatives and processes for preparation thereof
06/12/1990US4933493 Intermediates for the preparation of 4-phenyl-1,3-benzodiazepines
06/05/1990US4931429 α-aminoacyl β-aminoacyl aminodiols as anti-hypertensive agents
06/05/1990CA1269977A1 Indene compounds
05/1990
05/23/1990EP0369334A2 1-Aminoalkyl-3-oxysubstituted-4-aryl-1,3,4,5-tetrahydro-2H-1,3-benzodiazepine-2-ones, a process for their preparation and their use as medicaments
05/22/1990CA1269373A1 Thieno-triazolo-1,4-diazepino-2-carboxylic acid amides
05/17/1990WO1990004917A1 Heterocyclic peptide renin inhibitors
05/14/1990CA2002853A1 Potent inducers of terminal differentiation and method of use thereof
05/14/1990CA2002774A1 1-aminoalkyl-3-oxysubstituted-4-aryl-1,3,4,5-tetrahydro-2h- 1,3-benzodiazepine-2-ones, a process for their preparation and their use as medicaments
05/02/1990EP0366301A2 Preparation of 1,4-diazabicyclo [3.2.2]nonane
05/02/1990EP0365992A1 Heterocyclic peptide renin inhibitors
04/1990
04/25/1990CA2001211A1 Preparation of 1,4-diazabicyclo ¬3.2.2.| nonane
04/19/1990CA2000929A1 Heterocyclic peptide renin inhibitors
04/18/1990EP0363836A2 Use of homopiperazines in the preparation of a medicament for preventing or treating organ rejection reactions
04/17/1990US4918186 Process for producing cyclic ureas
04/17/1990US4918073 Diarylalkyl-substituted alkylamines and medicaments containing them
04/11/1990CA2000333A1 Use of homopiperazines for the preparation of a pharmaceutical for the prevention and treatment of organ rejection reactions
04/05/1990WO1990003371A1 2-hydroxy-3-phenoxy-propyl-substituted piperazines and homopiperazines, their manufacture and use
03/1990
03/29/1990DE3831993A1 2-hydroxy-3-phenoxy-propyl-substituierte piperazine und homo-piperazine, ihre herstellung und verwendung 2-hydroxy-3-phenoxy-propyl-substituted piperazine and homo-piperazine, their production and use
03/22/1990WO1990002737A1 Nasal administration of benzodiazepine hypnotics
03/21/1990EP0358903A2 Indazole-3-carboxylic acid derivatives
03/13/1990US4908446 Inhibitors of nonenzymatic cross-linking
03/13/1990US4908360 1-aminoalkyl-3-oxysubstituted-4-aryl-1,3,4,5-tetrahydro-2H-1,3-benzodiazepine-2-ones
03/06/1990US4906634 Novel N-[4-(aminosubstituted)phenyl]methanesulfonamides and their use as cardiovascular agents
02/1990
02/13/1990US4900820 Process for producing cyclic ureas
02/13/1990CA1265788A1 Tricyclic or tetracyclic compounds, process for the preparation thereof, and pharmaceutical composition containing the same
01/1990
01/23/1990US4895943 Bactericides
01/17/1990EP0350846A2 Condensed heterocyclic compounds and their use in therapy
01/10/1990CN1038644A Ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes
01/09/1990US4892875 Substituted heterocyclylalkyl esters of 1,4-dihydropyridine-3,5-dicarboxylic acids
12/1989
12/20/1989EP0346745A1 Condensed diazepinones, processes for their preparation and pharmaceutical preparations containing them
12/20/1989EP0346744A1 Condensed diazepinones, process for their preparation and medicaments containing them
12/06/1989EP0344543A2 Condensed diazepinones, process for their preparation and medicaments containing them
12/05/1989US4885152 Radioactive benzodiazepine derivatives
11/1989
11/29/1989EP0343830A2 Ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes
11/28/1989CA1263383A1 N-cyclised benzene sulfonamides, a process for their preparation and their use as active ingredient in pharmaceutical compositions
11/23/1989EP0342474A2 Use of diazepinones for the preparation of a medicament for therapy of microcirculatory disorders
11/14/1989US4880934 Preparation of hydroxyalkylpiperazinones by reacting a 2,3-dihydroxy-1,4-dioxane with a hydroalkyldiamine
11/08/1989EP0341081A2 Novel amino acid derivatives
11/07/1989CA1262726A1 Pyridine compounds, process for the preparation thereof and pharmaceutical composition containing the same
11/02/1989EP0339596A2 Antibiotics TAN-1057
10/1989
10/31/1989US4877877 Platelet aggregation inhibitors, vasodilators and anti-lipoperoxide generators
10/31/1989US4877875 1-Substituted alkyl-2-oxo-hexahydroquinoxaline derivatives
10/31/1989US4877785 Renin inhibitors
10/24/1989US4876345 Indene compounds
10/10/1989US4873236 Bradycardial agents
10/04/1989EP0335545A2 Pharmaceutical formulations for parenteral use
10/03/1989US4871843 Cyclic benzenesulfonamides, process for their preparation and their use as active substance of pharmaceutical compositions
09/1989
09/26/1989CA1261321A1 Piperidine compounds
09/19/1989CA1259612A1 Imidazodiazepine derivatives
09/13/1989EP0332570A2 Novel-N-(4-(Aminosubstituted)phenyl) methanesulfonamides and their use as cardiovascular agents
09/06/1989EP0330910A1 Propane derivatives
08/1989
08/29/1989US4861779 Anti-bacterial substituted bridged-diazabicycloalkyl quinolone carboxylic acids
08/22/1989US4859771 Process for resolution and racemization of amines with acidic α-hydrogens
08/22/1989CA1258653A1 Polymeric pyridinium ylide and products prepared from same
08/16/1989EP0327766A2 Redox systems for brain-targeted drug delivery
08/15/1989CA1258453A1 Piperazinecarboxamides having a phenoxyalkyl or thiophenoxyalkyl side chain
08/08/1989US4855502 α-(2-nitro-phenylmethyl)-benzylamines
06/1989
06/20/1989US4840948 Cardiotonic agents
06/06/1989US4837319 1-substituted alkyl-1,2-dihydro-2-pyrazinone derivatives
05/1989
05/24/1989EP0316852A2 Inhibitors of nonenzymatic cross-linking
05/24/1989EP0316690A2 Agent for the treatment of ischemic heart diseases
05/09/1989US4829061 1-(4-Hydroxy-3,5-di-tert.-butylbenzoyl)homopiperazine, various derivatives thereof, processes for the preparation of these compounds, medicaments containing them, and their use
05/03/1989EP0313847A2 Non-peptidyl alpha-succinamidoacyl aminodiols as anti-hypertensive agents
05/02/1989US4826861 Novel heterocyclic compounds substituted with an amino group, their processes of manufacture and the pharmaceutical compositions containing them
04/1989
04/26/1989EP0313291A1 Radioactive benzodiazepine derivative and processes for producing the same
04/26/1989EP0194416B1 Thieno-triazolo-1,4-diazepino-2-carboxamides, process for their preparation and pharmaceutical compositions
04/25/1989US4824840 Carbostyril derivatives and pharmaceutical preparations containing same
04/25/1989CA1253145A2 Fused aromatic oxazepinones, thiazepinones, diazepinones and sulfur analogs thereof
04/18/1989US4822914 Chemical intermediates; 4-phenyl-1,3-benzodiazepines
04/12/1989EP0311517A2 Amide compound having glutamate receptor inhibiting activity
04/11/1989US4820834 Gastrin, cholecystokinin antagonists
04/11/1989CA1252462A1 Imidazodiazepine derivatives
04/05/1989EP0310073A2 Non-peptidyl beta-aminoacyl aminodiol carbamates as anti-hypertensive agents
04/05/1989EP0310072A2 Non-peptidyl beta-succinamidoacyl aminodiols as anti-hypertensive agents
04/05/1989EP0310071A2 Non-peptidyl alpha-aminoacyl aminodiol carbamates as anti-hypertensive agents
04/05/1989EP0310070A2 Alpha-aminoacyl beta-aminoacyl aminodiols as anti-hypertensive agents
03/1989
03/30/1989DE3831543A1 Cyclohexyl phenyl ketone derivatives, process for their preparation and their use as intermediates
03/30/1989DE3831533A1 Process for the preparation of 1,4-benzodiazepin-2-one derivatives
03/29/1989EP0309425A2 New heterocyclic derivatives
03/29/1989EP0309424A2 New amidino derivatives
03/29/1989EP0309422A2 New amidino tricycle derivatives
03/21/1989US4814443 Preparation of hydroxyalkylpiperazinones by reacting glyoxal with hydroxyalkyldiamines
02/1989
02/28/1989US4808605 Tetrahydronaphthalene derivatives as calcium antagonists
01/1989
01/25/1989EP0300341A2 Benzodiazepine derivatives, their radiolabelled derivatives and use of the latter in immunoassays for detecting benzodiazepines
01/03/1989US4795751 5-substituted-6,8-difluoroquinolines useful as antibacterial agents
12/1988
12/28/1988CA1247612A Benzazepine derivatives
11/1988
11/29/1988CA1245647A1 Fused aromatic oxazepinones, thiazepinones, diazepinones and sulfur analogs thereof
11/01/1988CA1244024A1 .alpha.- ARYL-4-(4,5-DIHYDRO-3,5-DIOXO-1,2,4-TRIAZIN- 2(3H)-YL)BENZENEACETONITRILES
11/01/1988CA1244016A1 Condensed diazepinones, processes for preparing them and pharmaceutical compositions containing these compounds
10/1988
10/25/1988US4780493 Novel piperidine compounds
10/18/1988US4778796 ω-(3-pyridyl)alkenamide derivatives and anti-allergenic pharmaceutical compositions containing same
10/18/1988US4778789 Piperazinecarboxamides having a phenoxyalkyl or thiophenoxyalkyl side chain
10/11/1988US4777265 Preparation of acrylates and methacrylates
10/11/1988US4777169 Radioimmunoassay
10/04/1988US4775671 Imidazodiazepines
10/04/1988US4775668 Substituted bridged-diazabicycloalkyl quinolone carboxylic acids and anti-bacterial use thereof
09/1988
09/28/1988EP0284256A1 Benzodiazepine analogs
08/1988
08/31/1988EP0280472A1 Benzodiazepine analogs
08/30/1988CA1241327A1 Rhodanine derivative, process for preparing the same and pharmaceutical composition containing the same
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