Patents
Patents for C07D 239 - Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings (42,619)
02/2003
02/06/2003WO2002032871A3 Compounds and methods for treating multidrug resistance
02/06/2003US20030027829 Potassium channel inhibitors
02/06/2003US20030027807 Vitronectin receptor antagonists, their preparation and their use
02/06/2003US20030027794 N-heterocyclic derivatives as NOS inhibitors
02/05/2003EP1280793A2 Cyclic amidine compounds and their use as alpha4beta2 nicotinic acetylcholine receptor ligands
02/05/2003EP1280781A1 5-ht 7 receptor antagonists
02/05/2003EP1280764A2 Inhibitors of histone deacetylase
02/05/2003EP1223918B1 Pharmaceutical compositions comprising a hmg coa reductase inhibitor
02/05/2003EP1117653B1 Quinoline and quinazoline derivatives and their use as inhibitors of cytokine mediated diseases
02/05/2003EP1042303B1 Chloropyrimidine process
02/05/2003CN1395566A Corticotropin releasing factor antagonists
02/05/2003CN1394857A Compound used as antiproliferative agent and glycinamide ribonucleotide transformylase inhibitor
02/05/2003CN1100777C N-heterocyclic derivatives as NOS inhibitor
02/05/2003CN1100764C 2[(2-alkoxy-6-trifluoromethyl pyriidine-4-yl)-oxymethylene]-phenyl-acetic acid derivatives, their preparation and intermediate products and use
02/05/2003CN1100760C Process for preparation of arylamides of heteroarometic carboxylic acids
02/05/2003CN1100755C Aminophenyl ketone derivative and preparation method thereof
02/05/2003CN1100754C Method for producing trifluoroacetoacetic acid anilides
02/05/2003CN1100748C Inhibition of matrix metalloproteases by 2-substituted-4-(4-substituted phenyl)-4-oxobutyric acids
02/05/2003CN1100540C Protein tyrosine kinase aryl and heteroaryl quinazoline compounds having selective inhibition of HER-2 autophosphorylation properties
02/04/2003USRE37979 Pyrimidine derivatives and anti-viral agent containing the same as active ingredient thereof
02/04/2003US6515124 Dehydroamino acids
02/04/2003US6514934 For treating sexual dysfunctions in males and females
02/04/2003CA2290766C Method of treating nitrate-induced tolerance
02/04/2003CA2271566C Substituted phenyl pyrimidines useful in the treatment of cns disorders
01/2003
01/30/2003WO2003008388A1 I-form crystal of n-{2-chloro-4-[(6,7-dimethoxy-4-quinazolinyl)oxy]phenyl}-n'-propylurea and process for producing the same
01/30/2003WO2003008387A1 Compounds useful for treatment or prevention of disease mediated by alpha-2b-adrenoceptor
01/30/2003WO2003007965A1 Asymmetric synthesis of quinazolin-2-ones useful as hiv reverse transcriptase inhibitors
01/30/2003WO2003007963A1 Pyrimidine derivatives and their use in the treatment of neurodegenerative diseases
01/30/2003WO2003007798A2 Ophthalmic use of 5 fluorourcil
01/30/2003WO2002018375A1 Quinazolines, medicaments, which contain these compounds and which are effective as tyrosine kinase inhibitors, their use, and methods for the production thereof
01/30/2003WO2002018351A1 Bicyclic heterocycles, medicaments containing these compounds, their use, and methods for the production thereof
01/30/2003US20030023086 For therapy of thrombosis in humans and other mammals
01/30/2003US20030022908 2-alkoxy-5-methoxypyrimidines or their tautomeric forms and methods for producing the same
01/30/2003US20030022907 Anxiolytic agents and analgesics
01/30/2003US20030022905 Prevention and/or therapy of ischaemia and reperfusion damage; poly(ADP-ribose)-synthetase inhibitors
01/30/2003US20030022903 Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation
01/30/2003US20030022902 Based upon 2-(N-(7-benzyl-9-methyl-1,5-dioxonan-2,6-dione-3-yl)amido)-3-hydroxy-4 -methoxypyridine; use as agricultural fungicide
01/30/2003US20030022794 Bioactive pesticides
01/30/2003CA2454187A1 Compounds useful for treatment or prevention of disease mediated by alpha-2b-adrenoceptor
01/30/2003CA2417955A1 Quinazolines, pharmaceutical compositions containing these compounds, their use and processes for preparing them
01/29/2003EP1278748A2 Inhibitors of human phosphatidyl-inositol 3-kinase delta
01/29/2003EP1278735A1 2,4-di(hetero-)arylamino(-oxy)-5-substituted pyrimidines as antineoplastic agents
01/29/2003EP1210349B1 PYRAZOLO 4,3-d]PYRIMIDINES
01/29/2003EP0929597B1 Supramolecular polymer
01/29/2003CN1100046C 喹唑啉衍生物 Quinazoline derivatives
01/29/2003CN1100045C N-cyanoaryl nitrogen heterocycles with sulphur-containing groupings
01/29/2003CN1100044C Process for preparing substituted aryluracils
01/29/2003CN1100043C Sulfonamide derivative and process for preparing same
01/28/2003WO2002010155A1 Substituted aryl ketones and their use as herbicides
01/28/2003US6511941 Synergistic mixture
01/28/2003US6511659 Treatment of alopecia, cosmetics
01/28/2003CA2417385A1 Substituted aryl ketones and their use as herbicides
01/23/2003WO2003006457A1 Variolin derivatives and their use as antitumor agents
01/23/2003WO2003006454A2 Heterocyclic carboxamides and their use as fungicides
01/23/2003WO2003006443A2 2- 4-(naphtalin-2-yl)-thiazol-2-ylaminocarbonyl benzoic acid and 2- 4-(naphtalin-2-yl)-pyrimidin-2-ylaminocarbonyl benzoic acid and additional compounds serving as telomerase inhibitors for use in tumor therapy
01/23/2003WO2003006439A1 Preparation of aminopyrimidine compounds
01/23/2003WO2003006423A1 N-(3-amino-2-hydroxy-propyl) substituted alkylamide compounds
01/23/2003WO2002098367A3 Hybrid 2-aminotetralin and aryl-substituted piperazine compounds and their use in altering cns activity
01/23/2003WO2002046171A3 Anilinopyrimidine derivatives as ikk inhibitors and compositions and methods related thereto
01/23/2003US20030018199 Process for preparing chiral diol sulfones and dihydroxy acid HMG CoA reductase inhibitors
01/23/2003US20030018080 N-methoxymethyl-5,5-diphenylbarbituric acid
01/23/2003US20030018070 Bisaryl compound and medicament for cancer treatment comprising the same
01/23/2003US20030018052 Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation
01/23/2003US20030018039 Viricides
01/23/2003US20030018034 Piperazine compounds and medicinal use thereof
01/23/2003US20030018029 Tyrosine kinase inhbitor; antiproliferative agents
01/23/2003US20030018012 Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation
01/23/2003CA2453503A1 N-(3-amino-2-hydroxy-propyl) substituted alkylamide compounds
01/22/2003EP1277746A2 N-benzylpiperazine derivatives, process for their preparation and pharmaceutical compositions thereof
01/22/2003EP1277741A1 Cyclic compounds
01/22/2003EP1277740A1 Inhibitors of p38
01/22/2003EP1277738A1 Condensed heteroaryl derivatives
01/22/2003EP1277729A1 Ppar (gamma) modulators
01/22/2003EP1277726A1 Process for the preparation of 2-halobenzoic acids
01/22/2003EP1276732A1 Amides of r-2-(aminoaryl)-propionic acids for use in theprevention of leucocyte activation"
01/22/2003EP1276731A2 Branched adamantyl and noradamantyl aryl- and aralkylpiperazines with serotonin 5-ht 1a activity
01/22/2003EP1276728A2 Ultrashort acting hypnotic barbiturates
01/22/2003EP1276727A1 Novel amino carboxy alkyl derivatives of barbituric acid
01/22/2003EP1276496A2 Combined treatment with keratinocyte growth factor and epidermal growth factor inhibitor
01/22/2003EP0973774B1 1,5-dihydro-pyrazolo 3,4-d]-pyrimidinone derivatives
01/22/2003EP0646115B1 Heterocyclic-cyclic amine derivatives
01/22/2003CN1392874A Cyclic amidine compounds
01/22/2003CN1099425C 新的肽衍生物 New peptide derivatives
01/21/2003US6509341 The invention relates to carboxylic acid derivatives of formula (I), wherein the substituents have the meaning as commented in the description. It also relates to the production and use of same as endothelin receptor antagonists.
01/16/2003WO2003005025A1 Methods for identifying compounds modulating the activity of ppar-gamma
01/16/2003WO2003004474A1 Pesticidally active aminoacetonitriles
01/16/2003WO2003004458A1 New compounds
01/16/2003US20030013847 Pyruvate derivatives
01/16/2003US20030013846 Cytoprotective agents
01/16/2003US20030013729 Antilipemic agents; hypoglycemic agents; cardiovascular disorders; antidiabetic agents
01/16/2003US20030013728 Inhibitors of thrombin induced platelet aggregation
01/16/2003US20030013721 Antiinflammatory agents; immunology; cardiovascular disorders; rheumatic disorders
01/16/2003US20030013717 Cyclooxygenase inhibitor
01/16/2003US20030013713 Compounds as PDE IV and TNF-inhibitors
01/16/2003US20030013706 Autoimmune disease; antiinflammatory agents
01/16/2003US20030013674 Gene therapy; in situ supplying of genes; nucleic acid complex
01/16/2003US20030013657 Reducing oxidation stresses; central nervous system disorders; antiinflammatory agents
01/16/2003US20030013656 Reducing oxidation stresses; central nervous system disorders; antiinflammatory agents
01/16/2003CA2394010A1 Novel n-benzylpiperazine derivatives, their preparation and pharmaceutical compositions containing them
01/15/2003EP1275301A1 Trisubstituted heterocyclic compounds and their use as fungicides