Patents
Patents for C07D 223 - Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom (8,732)
06/1999
06/03/1999WO1999026928A1 Synthesis of 11-aryl-5,6-dihydro-11h-dibenz[b,e]azepines
06/03/1999WO1999026628A1 Use of substituted 11-phenyl-dibenzazepine compounds for the treatment or prevention of sickle cell disease, inflammatory diseases characterized by abnormal cell proliferation, diarrhea and scour
06/03/1999CA2311243A1 Synthesis of 11-aryl-5,6-dihydro-11h-dibenz[b,e]azepines
06/03/1999CA2310773A1 Use of substituted 11-phenyl-dibenzazepine compounds for the treatment or prevention of sickle cell disease, inflammatory diseases characterized by abnormal cell proliferation, diarrhea and scour
06/02/1999CN1218454A Preparation of 1-alkoxycarbonyl-3-phenylpropyl derivatives
06/01/1999US5908954 Chemical intermediate
05/1999
05/27/1999WO1999025686A1 Cyclic amine derivatives and their use as drugs
05/26/1999CN1217334A Phosphoric-acid substituted benzo-aza-tropone-N-acetic acid derivative, preparing method and medicine thereof
05/25/1999US5907038 Azepanes
05/19/1999EP0916679A1 Benzazepinone-N-acetic acid derivatives having a phosphonic acid group, process for their preparation and medicaments containing these compounds
05/19/1999EP0915653A1 Il-8 receptor antagonists
05/11/1999US5902882 Asymmetrically hydrogenating an azepine compound in the presence of a ruthenium-diphosphine complex catalyst
05/06/1999WO1999021836A1 Substituted isoquinoline derivatives and their use as anticonvulsants
05/06/1999EP0912512A1 Sulphonamide derivatives and their use in the treatment of cns disorders
05/06/1999EP0688320B1 Tricyclic benzodiazepins, their use and preparation
05/06/1999CA2307030A1 Substituted isoquinoline derivatives and their use as anticonvulsants
04/1999
04/29/1999WO1999020599A1 Pharmaceutically active compounds and methods of use
04/29/1999CA2307597A1 Pharmaceutically active compounds and methods of use
04/28/1999EP0910564A1 D-amino acid derived inhibitors of cysteine and serine proteases
04/28/1999CN1215054A Bychclic fibrinogen antagonists
04/22/1999WO1999020081A2 Highly transparent non-metallic cathodes
04/22/1999WO1999018966A1 Parenteral formulations comprising carbamazepine or its derivatives
04/20/1999US5895815 Evaporation from reaction mixture from catalytic dehydrogenation of10,11-dihydro-5h-dibenz9(b,f)azepine; pharmaceutical intermediate
04/14/1999EP0908448A1 Thermally stable aminosulfur trifluorides
04/14/1999EP0908445A1 Oxidation dyeing composition for keratin fibres containing an amino acid derivative as oxidation base and aminoacid derivatives
04/14/1999EP0810991B1 1-aryl-2-acylamino-ethane compounds and their use as neurokinin especially neurokinin 1 antagonists
04/14/1999CN1214045A Process for aminocarbonylation of benzazepines and benzodiazepines
04/14/1999CN1214043A Benzyl(idene)-lactam derivatives, their prepn. and their use as selective (ant) agaonists of 5-ht1A-and/or 5-ht1D receptors
04/07/1999EP0906283A1 Substituted benzamide derivatives and their use as anticonvulsants
04/07/1999EP0906277A1 Method of purifying epsilon-caprolactam
04/07/1999CN1213370A Substituted sulfonic acid N-[(aminoiminomethyl) phenylalkyl]-azaheterocyclamide compounds
04/01/1999WO1999015178A1 Vitronectin receptor antagonist
04/01/1999WO1999014998A2 Method for preventing and treating hearing loss using sensorineurotrophic compounds
04/01/1999CA2304647A1 Method for preventing and treating hearing loss using sensorineurotophic compounds
04/01/1999CA2304000A1 Vitronectin receptor antagonist
03/1999
03/31/1999EP0729454B1 Process for manufacturing caprolactam
03/31/1999CN1212692A Substituted A2a-and diazacycloheptane and cyclooctane compounds and their use
03/24/1999EP0903349A2 CCR-3 receptor antagonists
03/24/1999EP0903337A1 Process for the preparation of 1-alkoxycarbonyl-3-phenylpropyl derivatives
03/24/1999CN1211572A Cyclic amine derivatives-CCR-3 receptor antagonists
03/17/1999EP0901468A1 PREPARATION OF LACTAMS FROM ALIPHATIC $g(a),$g(v)-DINITRILES
03/16/1999US5883251 Enzyme inhibitors
03/16/1999CA1340443C Imidoperoxycarboxylic acids, processes for their preparation and their use
03/11/1999WO1999011626A1 Integrin receptor antagonists
03/11/1999WO1999011614A1 Caprolactam production process
03/11/1999CA2304117A1 Integrin receptor antagonists
03/11/1999CA2302440A1 Caprolactam production process
03/09/1999US5880295 Process for the preparation of diamine intermediates useful in the synthesis of HIV protease inhibitors
03/09/1999US5880136 Sulfonamide fibrinogen receptor antagonists
03/04/1999WO1999009991A1 Novel amide derivatives
03/04/1999WO1999009984A1 Pyrrolidine and piperidine modulators of chemokine receptor activity
03/04/1999DE19738463A1 Verfahren zur Herstellung von Caprolactam A process for the preparation of caprolactam
03/04/1999CA2301566A1 N-acylated lipophilic amino acid derivatives
03/04/1999CA2298813A1 Pyrrolidine and piperidine modulators of chemokine receptor activity
03/03/1999EP0724570B1 Amidino derivatives useful as nitric oxide synthase inhibitors
02/1999
02/25/1999DE19837386A1 New CCR-3 antagonist piperazine derivatives and analogues
02/24/1999EP0897912A1 Amidino derivatives useful as nitric oxide synthase inhibitors
02/24/1999CN1209121A Benzazepine derivatives with vasopressin agonistic activity
02/23/1999US5874575 Preparation of caprolactam
02/23/1999US5874428 N-substituted aza-heterocyclic carboxylic acids and esters thereof
02/18/1999WO1999007672A1 Derivatives of 2,5- and 3,5-disubstituted anilines, their preparation and use
02/18/1999WO1999007377A1 1-[4-(substituted alkoxy)benzyl]naphthalene compounds having estrogen inhibitory activity
02/18/1999CA2298651A1 1-¬4-(substituted alkoxy)benzyl|naphthalene compounds having estrogen inhibitory activity
02/18/1999CA2245043A1 Ccr-3 receptor antagonists
02/17/1999CN1208405A Retroviral protease inhibiting compounds
02/16/1999US5872118 Relaxation of skeletal muscle in spastic, hypertonic and hyperkinetic conditions
02/11/1999WO1999006049A1 Integrin receptor antagonists
02/11/1999WO1999006042A1 Caspases and apoptosis
02/11/1999CA2298668A1 Caspases and apoptosis
02/11/1999CA2298544A1 Integrin receptor antagonists
02/10/1999EP0895989A1 1-[4-(Substituted alkoxy)benzyl] naphthalene compounds having estrogen inhibitory activity
02/09/1999US5869483 Tricyclic benzazepine vasopressin antagonists
02/04/1999WO1999005147A1 Thiazolobenzoheterocycles, preparation and medicines containing same
02/03/1999EP0894088A1 Substituted sulfonic acid n- (aminoiminomethyl)phenylalkyl]-azaheterocyclamide compounds
02/03/1999EP0894085A1 Benzyl(idene)-lactam derivatives, their preparation and their use as selective (ant)agonists of 5-ht1a- and/or 5-ht1d receptors
02/03/1999CN1041921C Bicyclic fibrinogen antagonists
02/02/1999US5866566 Derivatives of 10, 11-Dihydro-10-OXO-5H-Dibenz/B,F/Azepine-5-carboxamide
01/1999
01/28/1999WO1998046576A3 Halo-alkoxycarbonyl prodrugs
01/20/1999EP0891325A1 Para-substituted phenylpropanoic acid derivatives as integrin antagonists
01/20/1999CN1041720C Bicyclic amide derivatives, its prepn. method, medicinal compsns. and medical application
01/19/1999US5861418 Aminobenzoic acid derivatives
01/13/1999EP0889877A1 META-SUBSTITUTED PHENYLENE DERIVATIVES AND THEIR USE AS ALPHAvBETA3 INTEGRIN ANTAGONISTS OR INHIBITORS
01/12/1999US5859239 Mercaptoalkanoylamino and acylmercaptoalkanoylamino benzoxazepines and benzothiazepines
01/12/1999US5859029 Heterocyclic compounds method of preparing them and pharmeutical compositions in which they are present
01/12/1999US5858995 Administering to humans and animals in the treatment of diseases caused by abnormal bone metabolism
01/12/1999US5858736 Contacting dinitrile in aqueous mixture with enzyme catalyst having aliphatic nitrilase activity or combination of nitrile hydratase and amidase activity, contacting product with hydrogen and hydrogenation catalyst to produce lactam
01/12/1999CA2110917C Reagents and methods for the quantification of amitriptyline or nortriptyline in biological fluids
01/07/1999WO1999000371A1 Phenylalkyl derivatives with thrombin-inhibiting effect
01/07/1999WO1999000362A1 Synthesis of aminocarbonyl substituted lactams
01/07/1999WO1999000115A1 Use of antagonists or partial agonists of the vanilloid receptor complexes for treating neurodegenerative diseases
01/07/1999EP0888436A1 Solid composition of heterocyclic compounds and/or oxime esters and inert porous carrier materials
01/07/1999DE19727117A1 Phenylalkylderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung Phenylalkylderivate, pharmaceutical compositions containing them and methods for their preparation
01/07/1999CA2295089A1 Use of antagonists or partial agonists of the vanilloid receptor complexes for treating neurodegenerative diseases
01/07/1999CA2288744A1 Phenylalkyl derivatives, pharmaceutical compositions containing these compounds and processes for preparing them
01/05/1999US5856564 Condensed benzazepine derivative and pharmaceutical composition thereof
01/05/1999US5856477 Hypotensive agents; congestive heart failure
01/05/1999US5856476 Processes for preparing azepiones useful as intermediates in the preparation of inhibitors of angiotensin converting enzyme and neutral endopeptidase
01/05/1999US5856318 Nitrogen-containing cyclohetero cyclo-heteroaminoaryl derivatives for CNS disorders
12/1998
12/29/1998US5854274 Tricyclic heterocyclic sulfonamide and sulfonic ester derivatives
12/29/1998US5854236 Tricyclic benzazepine vasopressin antagonists
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