Patents
Patents for C07C 277 - Preparation of guanidine or its derivatives, i.e. compounds containing the group the singly-bound nitrogen atoms not being part of nitro or nitroso groups (1,361)
06/1999
06/08/1999CA2089972C Sulfonamidocarboxamides
06/02/1999CN1218039A The preparation of substituted guanidine derivatives
06/02/1999CN1218038A The preparation of substituted guanidine derivatives
06/02/1999CN1218037A The preparation of substituted guanidine derivatives
06/02/1999CN1218036A The preparation of substituted guanidine derivatives
05/1999
05/12/1999EP0915085A2 Process for the preparation of substituted guanidine derivatives
05/12/1999EP0915084A2 Process for the preparation of substituted guanidine derivatives
05/12/1999EP0915083A2 Process for the preparation of substituted guanidine derivatives
05/12/1999EP0915082A2 Process for the preparation of substituted guanidine derivatives
04/1999
04/21/1999CN1214691A Process for preparation of N-methyl-D-phenylalanyl-N-[1-[3-[(aminoiminomethyl)-amino] propyl]-3,3-difluoro-2-oxohexyl]-L-prolinamide
04/15/1999WO1999018053A1 Preparation of radiolabelled haloaromatics via polymer-bound intermediates
04/13/1999CA2143216C 15-deoxyspergualin analogs, their method of preparation and their use in therapeutics
04/13/1999CA2110437C 15-deoxysperqualin analogs, their method of preparation and their use in therapeutics
04/06/1999CA2024700C Benzoylguanidines, a process for their preaparation, their use as medicaments and medicaments containing them
03/1999
03/31/1999EP0701550B1 Process for the production of aminoalkylguanidines
03/16/1999US5883133 Cardiovascular disorders
03/16/1999US5883132 Multistage reaction of amidation, activation, coupling and hydrolysis
03/09/1999US5880156 Antiarrhythmia agents
02/1999
02/24/1999EP0703900B1 PROCESS FOR THE PREPARATION OF PHENYLALANINE DERIVATIVES OR HOMOLOGUES CONTAINING A GUANIDINO OR MODIFIED GUANIDINO GROUP USEFUL FOR THE PREPARATION GnRH OF ANTAGONISTIC PEPTIDES
02/16/1999US5872294 Phase transfer agents of hexasubstituted guanidium chlorides
02/09/1999US5869734 Chemical intermediate to the production of deoxyspergualin and salts
02/09/1999US5869531 No undesireable salidiuretic properties; treating ischemia induced disorders
02/03/1999EP0894083A1 Creatine pyruvates and method for their production
02/02/1999US5866610 Substituted benzoylguanidines, process for their preparation, their use as a pharmaceutical as inhibitors of the cellular NA+/H+ exchange or as a diagnostic, and pharmaceutical containing them
01/1999
01/20/1999EP0693053B1 Urea and amide derivatives and their use in the control of cell membrane potassium channels
01/07/1999EP0888367A1 Isolated rna molecules which bind to arginine and uses thereof
12/1998
12/15/1998US5849775 Substituted benzoylguanidines process for their preparation, their use as a medicament or diagnostic, and pharmaceutical containing them
12/09/1998EP0882014A1 Process for the preparation of n?g -monomethyl-l-arginine hydrochloride
11/1998
11/24/1998US5840972 Process for preparing NG -monoalkyl-L-arginine and related compounds
11/24/1998US5840761 Antiarrhythmia agents, inhibitors of the cellular na+/h+ antiporter
11/18/1998EP0746404B1 Process for recovering guanidine salts
10/1998
10/14/1998EP0755380B1 15-deoxyspergualin analogs, therapeutical use thereof, and method for preparing same
10/08/1998WO1998043951A1 Method for producing n-alkyl-n'-nitroguanidines
10/01/1998DE19712885A1 Verfahren zur Herstellung von N-Alkyl-N'-nitroguanidinen Nitroguanidines N-alkyl-N'-process for the preparation of
09/1998
09/15/1998US5807896 Antiarrhythmia agents; sodium channel modulators; cardiovascular disorders
08/1998
08/26/1998EP0859591A1 Use of at least one no synthase inhibitor for treating sensitive skin
08/26/1998CN1191216A Process for synthesis of guanidine dihydrogen phosphate and guanidine hydrogen phosphate
08/13/1998WO1998034647A1 Arginine silicate inositol complex and use thereof
08/13/1998CA2279233A1 Arginine silicate complex and use thereof
07/1998
07/21/1998US5783734 Process for preparing N-methyl-N'-nitroguanidine
07/14/1998US5780658 Process for the synthesis of cationic surfactants comprising esterification with basic character amino acids
07/02/1998WO1998028263A1 Creatine pyruvates and method for their production
06/1998
06/09/1998US5763604 Anticoagulants
06/02/1998US5759406 Adsorption process for organic base recovery from aqueous brine solutions
05/1998
05/27/1998CN1182735A Diphenolic quaternary salt, its preparational process and usage
05/26/1998US5756843 Quaternary bisphenolates, methods for their preparation, and uses thereof
05/05/1998US5747541 Substituted benzoylguanidines, a process for their preparation, their use as medicament of diagnostic agent, and medicament comprising them
05/05/1998US5747539 Fluorine-containing benzoylguanidines
04/1998
04/28/1998US5744450 GnRH analogs
04/15/1998CN1038032C £(Benzodioxan, benzofuran or benzopyran) alkylamino| alkyl substituted guanidines and its preparing method, use and intermediate
03/1998
03/31/1998US5733934 Antiarrythmic and cardioprotective substituted indenoylguanidines
03/31/1998US5733928 15-deoxyspergualin analogs, their method of preparation and their use in therapeutics
03/24/1998US5731351 Antiarrhythmia agents
03/04/1998CN1174833A Phenyl substituted alkenocarboxylic guanidine, preparation method, application as medicine or diagnostic agent adn medicine containing it
02/1998
02/25/1998EP0825178A1 Phenyl-substituted alkenoylguanidides, process for their preparation, their use as drugs or in diagnostic agents and drugs containing them
02/17/1998US5719319 Process for the preparation of a creatine or creatine monohydrate
02/11/1998CN1037345C Method for preparing 1, 3 -di£(4 -chloro -benzoyl methylen) amino| guanidine-hydrobromate
01/1998
01/29/1998WO1998003518A2 New bis-platinum complexes with polymethylene derivatives as ligands having antitumor activity
01/21/1998EP0819469A2 Quaternary bisphenolates as phase transfer catalysts
01/21/1998CN1170716A Di-ortho substituted benzoyl guanidine, its preparing method, use and medicine containing them
01/20/1998US5710249 Amino acids and processes for making peptides using same
01/13/1998US5707970 Treatment of atheriosclerosis and as nutrients formed by reaction of arginine, silicate salt and inositol
12/1997
12/17/1997CN1167759A Substd. 2-naphthoyl guanidines, their preparing method, use and drug contg. them
12/09/1997US5696407 Heating to dissolve nitroguanidine in dipolar aprotic solvent, adding spherical control particles, gradient cooling to crystallization
12/09/1997US5696290 Synthesis of penta-substituted guanidines
12/09/1997US5696138 Urea derivatives and their use
12/09/1997CA1339577C Oligomeric cyanoguanidines
12/04/1997WO1997045109A1 Process of preparing 2,2'-(1-methyl-1,2-ethanediylidene)bis[hydrazine carboximidamide]
12/04/1997CA2252601A1 Process of preparing 2,2'-(1-methyl-1,2-ethanediylidene)bis¬hydrazine carboximidamide|
12/03/1997EP0810207A1 Bis-ortho-substituted benzoylguanidines, process for their preparation, their use as medicament or diagnostic agent and medicaments containing them
12/03/1997EP0810206A1 Substituted 2-naphtoylguanidines, process for their preparation, their use as medicament or diagnostic agent and medicament containing them
12/02/1997US5693672 3,4,5-substituted benzoylguanidines, process for their preparation, their use as a medicament or diagnostic and medicament containing them
11/1997
11/28/1997CA2206198A1 Bis-ortho-substituted benzoylguanidines, processes for their preparation, their use as a medicament or diagnostic, and medicament comprising them
11/18/1997US5688952 Vasoconstrictor intermediates
11/12/1997CN1164854A Novel synthesis of penta-substituted guanidines
11/05/1997CN1163888A Process for preparing N-methyl-N'-nitroguanidine
10/1997
10/29/1997CN1036267C Method for preparing amino-substituted benzoyl guanidines
10/21/1997US5679712 Antiarrhythmia agents, treatment of cardiovascular, nervous system disorders
10/14/1997US5677448 Sulfonamidocarboxamides
10/02/1997WO1997035874A1 Process for the preparation of n-methyl-d-phenylalanyl-n-[1-[3-[(aminoiminomethyl)amino]propyl]-3,3-difluoro-2-oxohexyl]-l-prolinamide
10/01/1997EP0798293A1 Process for the preparation of N-Methyl-N'-nitroguanidine
09/1997
09/24/1997EP0491708B1 Isolating aminoarginine and use to block nitric oxide formation in body
09/18/1997WO1997033895A1 Isolated rna molecules which bind to arginine and uses thereof
08/1997
08/28/1997WO1997030972A1 Process for the preparation of ng-monomethyl-l-arginine hydrochloride
08/19/1997US5659083 Process of preparing 2,2'-(1-methyl-1,2-ethanediylidene) bis[hydrazinecarboximidamide]
08/19/1997US5659071 Process for the production of aminoalkylguanidines
07/1997
07/16/1997EP0784051A1 Aqueous hexasubstituted guanidinium chlorides and methods for their preparation and use
07/09/1997EP0782984A2 Process of preparing 2-2'-(1-Methyl-1,2-Ethanediylidene) bis (Hydrazine carboximidamide)
07/09/1997CN1153773A substituted benzoyl guanidine its preparation, application as medicine or diagnostic reagent and medicine containing the said compound
07/02/1997EP0781272A1 Novel synthesis of penta-substituted guanidines
07/02/1997CN1153170A Substd. Benzene dicarboxylic biguanides, process for preparing same and their use as medicines and diagnosis agent, and medicines contg. same
07/02/1997CN1153169A Substd. benzene dicarboxylic biguanide amides, their preparing method, their use as medicines and diagnosis agent, and medicines contg. same
06/1997
06/10/1997US5637613 15-deoxyspergualin analogs, their method of preparation and their use in therapeutics
06/04/1997CN1150947A Alkenyl-benzoyl guanidine derivant
05/1997
05/20/1997US5631293 Cardiovascular disorders
05/01/1997WO1997015280A1 Use of at least one no synthase inhibitor for treating sensitive skin
04/1997
04/29/1997US5624952 Vasoconstrictors
04/02/1997EP0765867A1 Substituted benzoyl guanidines, process for their preparation, their use as antiarrhythmics or diagnostic agent as well as pharmaceuticals containing them
04/02/1997EP0765866A2 Preparation of optically active (S)-(-) and (R)-(+)- deoxyspergualin and novel intermediates thereof
03/1997
03/28/1997CA2186580A1 Substituted benzoylguanidines, a process for their preparation, their use as medicament or diagnostic agent, and medicament comprising them
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