Patents
Patents for C07C 277 - Preparation of guanidine or its derivatives, i.e. compounds containing the group the singly-bound nitrogen atoms not being part of nitro or nitroso groups (1,361)
06/2001
06/20/2001CN1300303A Enzyme inhibitors
05/2001
05/22/2001US6235934 Aqueous hexasubstituted guanidinium chlorides and methods for their preparation and use
05/16/2001CN1065861C Phenyl substituted alkenocarboxylic guanidine, preparation method application as medicine or diagnostic agent and medicine containing it
05/10/2001WO2001032611A1 N-guanidinoalkylamides, their preparation, their use, and pharmaceutical preparations comprising them
05/09/2001CN1065526C Process for preparing N-methyl-N'-nitroguanidine
05/02/2001EP1095933A1 Novel N-guanidinoalkylamides, their preparation, their use, and pharmaceutical preparations comprising them
04/2001
04/25/2001CN1064955C Fluorine-containing benzoylguanidines
04/03/2001US6211186 Polyoxyalkylene glycol modified with n-heterocycle derivative with amidine or guanidine group; diaper rash, obesity, acne, periodontal disease, contraceptives; protease and lipase inhibitors
03/2001
03/28/2001CN1063744C 15-deoxyspergulin analogs, their method of preparation and their use in therapeutics
03/21/2001CN1063438C Alkenyl-benzoyl guanidine derivant, prepn. method and use thereof
03/21/2001CN1063437C Fluorophenyl sbstd. alkenylc arboxylic acid guanidine its preparation method applied as medicine and diagnosis agent and medicine containing the compound
03/21/2001CN1063436C Fluoroalkyl-acyclic alkenyl substituted benzoylguanidines prepn. method and usage thereof
03/14/2001CN1287118A Method of preparing creatine or its hydrate
03/07/2001CN1062858C Phenyl-substd alkenylcarboguanidides carrying perfluoroalkyl groups, process for their preparation, their use as medicament and medicines
03/01/2001WO2001014323A1 Method for producing 1-methyl-3-nitroguanidine
02/2001
02/28/2001CN1062554C Substituted guanidine cinnamate, its prepn., its application as medicine or diagnosing agent and medicine containing the compound
02/27/2001CA2185165C Process for the synthesis of cationic surfactants derived from the condensation of fatty acids with esterified basic-character amino acids and their application as antimicrobial agents
02/22/2001DE19939609A1 Pure 1-methyl-3-nitroguanidine preparation in high yield for use as insecticide intermediate, by reacting cyanogen halide with methylamine then ammonium nitrate and dehydrating product
02/14/2001CN1061974C Process for synthesis of guanidine dihydrogen phosphate and guanidine hydrogen phosphate
02/08/2001WO2001009091A1 Method for producing protected acyl guanidines by way of mukaiyama reaction
02/07/2001CN1061648C Antiarrhythmic and cardioprotective substituted indenoyiguanidines
02/07/2001CN1061647C Process for preparing creatine or creatine hydrate
02/01/2001DE19935693A1 Verfahren zur Herstellung geschützter Acylguanidine durch Mukaiyama Reaktion Process for the preparation of protected acylguanidines by Mukaiyama reaction
01/2001
01/25/2001WO2001005753A1 Diacylhydrazine derivatives
01/25/2001WO2001005752A1 Aminoguanidine bicarbonate with particular properties and method for making same
01/25/2001CA2379041A1 Diacylhydrazine derivatives
01/18/2001DE19932796A1 Diacylhydrazinderivate Diacylhydrazinderivate
01/17/2001CN1060763C Urea-substituted benzoylguanidines, process for their preparation, and use and pharmaceutical containing them
01/09/2001US6172111 Salt formation; antiobesity and strengthening agents
01/09/2001CA2117483C [(benzodioxan, benzofuran or benzopyran)-alkylamino] alkyl substituted guanidines as selective vascoconstrictors
01/04/2001WO2001000623A1 Method of producing nitroguanidine- and nitroenamine derivatives
01/04/2001WO2001000571A1 Process for preparing substituted cyclopentane derivatives and novel crystalline structures thereof
01/04/2001WO2001000558A1 Preparation of substituted cyclopentane and cyclopentene compounds and certain intermediates
01/04/2001WO2000035868A3 Methods for the synthesis of alpha-hydroxy-beta-amino acid and amide derivatives
01/04/2001CA2377287A1 Preparation of substituted cyclopentane and cyclopentene compounds and certain intermediates
01/04/2001CA2377240A1 Process for preparing substituted cyclopentane derivatives and novel crystalline structures thereof
12/2000
12/27/2000EP1062264A2 Enzyme inhibitors
12/05/2000US6156735 Arginine silicate inositol complex and use thereof
11/2000
11/14/2000US6147258 Preparation of substituted guanidine derivatives
11/07/2000US6143929 Comprising reacting an o-alkylisourea salt and a primary or secondary amine in the presence of crystals of a guanidine derivative
10/2000
10/26/2000WO2000035860A3 Acyl isothiocyanate resins and their use in solid-supported synthesis of guanidines
10/25/2000CN1057760C Amino acid substituted benzoylguanidines, process for their preparation, their use and medicament containing them
09/2000
09/26/2000US6124466 Nitroisourea derivative
09/06/2000CN1265392A Method for preparation of guanifine derivatives
09/05/2000US6114581 Method for producing N-alkyl-N'-nitroguanidines
08/2000
08/30/2000CN1055920C Aklyl benzoylguanidines derivatives
08/30/2000CN1055919C Arylbenzoylguanidin
08/23/2000CN1263886A Method for preparing guanidine derivative
08/17/2000DE19905711A1 Verfahren zur Herstellung von Guanidinderivaten A process for preparing guanidine derivatives
08/16/2000EP1028106A1 Process for the preparation of guanidine derivatives
08/16/2000CN1055463C Process for manufacture of guanidines
08/09/2000CN1262271A Process for preparing tetramethyl guanidine
08/08/2000US6100428 Reacting optionally protected thioureas and isothioureas with amines in the presence of a nickel catalyst to form a compound comprising a guanidine; high yields, mild reaction conditions
07/2000
07/25/2000US6093848 Preparation of substituted guanidine derivatives
07/20/2000WO2000042001A1 ((aminoiminomethyl) amino) alkanecarboxamides and their applications in therapy
07/13/2000WO2000040549A1 Method for producing robenidine or derivatives thereof
07/13/2000WO2000040548A1 Arylalkanoyl derivatives, processes for their preparation, their use and pharmaceutical compositions containing them
07/12/2000CN1054373C Full fluoralkyl-substituted bezoylguanidine prepn. pharmaceutical use of same and pharmaceutical containing same
07/11/2000US6087304 Substituted 2-naphthoylguanidines, process for their preparation, their use as a medicament or diagnostic, and medicament containing them
06/2000
06/29/2000DE19860048A1 Verfahren zur Herstellung von Guanidinderivaten A process for preparing guanidine derivatives
06/28/2000EP1013640A1 Synthesis of guanidines from O-alkylisoureas using a crystal seed
06/28/2000EP1012165A1 Process for the preparation of n-methyl-d-phenylalanyl-n- 1- 3- (aminoiminomethyl)amino]propyl]-3,3-difluoro-2-oxohexyl]-l-prolinamide
06/22/2000WO2000035868A2 Methods for the synthesis of alpha-hydroxy-beta-amino acid and amide derivatives
06/22/2000WO2000035860A2 Acyl isothiocyanate resins and their use in solid-supported synthesis of guanidines
06/22/2000CA2354476A1 Methods for the synthesis of alpha-hydroxy-beta-amino acid and amide derivatives
06/14/2000EP1007096A1 Arginine silicate inositol complex and use thereof
06/02/2000WO2000031025A1 Method of producing n-alkyl-n'-nitroguanidine
05/2000
05/31/2000DE19956593A1 Production of N-alkyl-N'-nitroguanidine, especially N-methyl-N'-nitroguanidine, involves adding alkylamine solution to a suspension of nitroguanidine at elevated temperature and removing ammonia
05/24/2000CN1253945A Method for preparing creatine or creatine-hydrate
05/23/2000US6066673 Enzyme inhibitors
05/09/2000US6060616 Antitumors agents; leukemia, ovarian carcinoma
04/2000
04/20/2000WO2000021920A1 Diaminopropionic acid derivatives
04/19/2000CN1251089A Method for producing N-alkyl-N'-nitroguanidines
03/2000
03/30/2000DE19843764A1 Production of 1-aralkyl biguanide derivatives useful as herbicide intermediates comprises reacting aralkylamine compounds with dicyanodiamide at high temperature in temperature controlling diluent
03/23/2000WO1999046316A3 Enzyme inhibitors
03/16/2000DE19841525A1 Verfahren zur Herstellung von Kreatin oder Kreatin-monohydrat A process for the preparation of creatine or creatine monohydrate
03/15/2000EP0985661A1 Process for the preparation of creatine or creatine monohydrate
03/08/2000CN1246801A Arginine silicate inositol complex and use thereof
03/01/2000CN1049888C Process for preparing benzoylguanidine
02/2000
02/15/2000US6025349 Phenyl.-substituted alkenylcarboguanidides carrying perfluoroalkyl groups, a process for their preparation, their use as a medicament or diagnostic agent, and also a medicament containing them
01/2000
01/26/2000EP0974579A1 Novel nitroisourea derivatives
01/19/2000EP0971886A1 Method for producing n-alkyl-n'-nitroguanidines
01/05/2000CN1240207A Production process of high-purity creatine and its monohydrate
12/1999
12/21/1999US6005010 Cardiovascular disorders, antiarrhythmia agents and antiischemic agents
12/07/1999US5998481 Fluoroalkyl/alkenyl-substituted benzoylguanidines, process for their preparation, their use as a medicament or diagnostic, and medicament containing them
12/01/1999EP0696274B1 Process for preparing ng-monoalkyl-l-arginine and related compounds
11/1999
11/30/1999US5994582 Preparation of substituted guanidine derivative
11/03/1999EP0894083B1 Creatine pyruvates and method for their production
10/1999
10/28/1999WO1999054291A1 Method for producing polyhexamethylene guanidine
10/26/1999US5973005 Aqueous creatine solution and process of producing a stable, bioavailable aqueous creatine solution
10/19/1999US5969182 Preparation of substituted guanidine derivatives
10/19/1999US5969086 Quaternary bisphenolates, methods for their preparation, and uses thereof
10/06/1999CN1045431C 15-deoxyspergualin analogs, their preparation method, compositions, intermediate and use in preparation of medicine thereof
09/1999
09/16/1999WO1999046316A2 Enzyme inhibitors
09/16/1999CA2323496A1 Enzyme inhibitors
09/02/1999WO1999043312A1 Aqueous creatine solution and process of producing a stable, bioavailable aqueous creatine solution
08/1999
08/17/1999US5938907 Electrodialysis to separate guanidine salts from aqueous solutions contaminated with residual proteins, buffers, reducing agents; simplification
07/1999
07/28/1999CN1224416A Creatine pyruvates and method for their production
06/1999
06/09/1999EP0921117A2 Acylguanidines
06/09/1999EP0920434A2 Bis-platinum complexes with polymethylene derivatives as ligands having antitumor activity
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