| Patents for C07B 55 - Racemisation; Complete or partial inversion (688) |
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| 12/03/2008 | EP1430031B1 Kinetic resolution of a intermediate useful in the production of benazepril and analogues thereof |
| 11/26/2008 | EP1506162B1 Synthesis of benzonitriles and benzimidates |
| 11/20/2008 | US20080287704 Preparative-scale separation of enantiomers of chiral carboxylic acids |
| 10/01/2008 | EP1620390B1 Method for the synthesis of 4-hydroxyisoleucine and the derivatives thereof |
| 09/30/2008 | US7429675 reacting 2-{[2-(4-hydroxyphenyl)ethyl]thio}-3-[4-(2-{4-[(methylsulfonyl)oxy]phenoxy}ethyl)phenyl]propanoic acid enriched in one enantiomer with a halosilane such as chlorotrimethylsilane in presence of 1,8 diazobicyclo[5.4.0]undecec-7-ene; antidyslipidemia an organic base |
| 09/09/2008 | CA2412047C Shortened synthesis of 3,3-diarylpropylamine derivatives |
| 09/04/2008 | DE112006001701T5 Verfahren zur Herstellung von optisch aktiven Benzylaminderivaten A process for the preparation of optically active benzylamine derivatives |
| 08/26/2008 | US7417165 Characterized by X-ray powder diffraction peaks at about 5.8, 18.4, 19.2, 20.7, and 23.7 degrees 2 theta +-0.2 degrees 2 theta, comprising crystallizing the pregabalin from a mixture of acetonitrile and an alcohol; use as pharmaceutical dosage form of drug with targeted release profile |
| 08/20/2008 | EP1363872B1 Method for isolating and purifying (1rs,2rs)-2- (dimethylamino)methyl -1-(3-methoxyphenyl)-cyclohexanol |
| 07/08/2008 | US7396941 Method for producing monatin |
| 07/02/2008 | EP1937620A2 Resolution of alpha-(phenoxy) phenylacetic acid derivatives with naphthyl-alkylamines |
| 06/26/2008 | US20080153137 Stereoinversion of amino acids |
| 06/17/2008 | US7388098 Dynamic resolution of isomers and resolved isomers |
| 06/12/2008 | WO2008070143A1 Processes for preparing armodafinil intermediate |
| 06/03/2008 | US7381835 Resolution of racemic mixtures using an amine |
| 04/15/2008 | US7358396 can be resolved using optically active carboxylic acids or enzymes; compounds such as 1-benzyloxy-3-aminobutane |
| 04/15/2008 | CA2349325C Process for converting an alcohol to the corresponding fluoride |
| 01/03/2008 | WO2008001718A1 Dehydroxylated fluorinating agent |
| 12/05/2007 | CN100352437C Piperazine derivatives, their preparation and their use for treating central nervous system (CNS) disorders |
| 11/13/2007 | US7294718 Synthesis of a 4-methylthiazole-4(S)-carboxylic acid compound |
| 11/13/2007 | CA2425557C Anticholinergic agents that can be used as medicaments and method for the production thereof |
| 10/23/2007 | US7285676 Synthesis of chiral 2-alkyl amino acids |
| 10/23/2007 | US7285670 4,5-Dihydro-2-(2,4-dihydroxyphenyl)-4-methyl-thiazole-4(S)-carboxylic acid by coupling a mono- or polyalkoxybenzonitrile with a cysteine ester and alkylating the thiazoline ring at the 4-carbon position; preferably a phase transfer agent such as N-9-anthracenylmethylcinchonidinium chloride is used |
| 10/17/2007 | CN101054331A Racemization method for asymmetry optical activity 2-heterocycle substituted dihydropyrimidines compound |
| 10/10/2007 | CN101052604A Deenrichment method for enantiomer enrichment substrate |
| 10/03/2007 | CN101048353A Catalyst compositions and their use in the de-enrichment of enantiomerically enriched substrates |
| 10/03/2007 | CN101048139A Compositions for controlled delivery of pharmaceutically active compounds |
| 09/19/2007 | CN100338068C Process for preparing clopidogrel |
| 08/01/2007 | EP1289929B1 Shortened synthesis of 3,3-diarylpropylamine derivatives |
| 07/25/2007 | EP1809586A1 Process for the de-enrichment of enantiomerically enriched substrates |
| 07/25/2007 | EP1809585A1 Catalyst compositions and their use in the de-enrichment of enantiomerically enriched substrates |
| 07/19/2007 | WO2007079563A1 Composition of chemicals for manipulating the behaviour of the pistachio twig borer, kermania pistaciella (lepidoptera: oinophilidae) |
| 07/11/2007 | EP1804771A2 Compositions for controlled delivery of pharmaceutically active compounds |
| 06/06/2007 | CN1974565A Process of racemizing 6-fluoro-3,4-dihydro-2H-1-benzopyran-2-formic acid |
| 04/03/2007 | US7199264 Separating alanine isomers from a racemic mixture, by amidation converting a nitrogen atom of an amino group into carbamate group, complexing with hydrophilic compound, isolate by the difference in the hydrophobicity; purification |
| 03/22/2007 | US20070066832 Method for producing monatin |
| 03/13/2007 | CA2208522C Racemisation process for use in the manufacture of levobupivacaine and related piperidinecarboxanilide anaesthetic agents |
| 02/28/2007 | CN1922140A Method for producing monatin |
| 01/31/2007 | CN1297540C New derivatives of pyridilethanol (phenylethyl) amines as cholesterol biosynthesis inhibitors, procedures of their preparation and pharmaceutical preparations which they contain |
| 01/09/2007 | CA2201780C Racemisation of precursors to levobupivacaine and analogues thereof |
| 01/09/2007 | CA2200490C Racemisation and asymmetric transformation processes used in the manufacture of levobupivacaine and analogues thereof |
| 01/04/2007 | WO2007000918A1 Benzylamine derivatives, method for optical resolution of benzylamine derivatives, process for production of benzylamine derivatives, process for production of optically active benzylamine derivatives, and process for production of (1r, 2s)-2-amino-1-(4-hydroxyphenyl)propan-1-ol |
| 01/04/2007 | DE102005031041A1 Isomerizing water-soluble salts of trans-tramadol, useful for preparing the cis-isomer, a known analgesic, comprises treatment with warm water in presence of acid catalyst |
| 01/03/2007 | CN1293081C 28-epirapalogs, preparation method, medicament composition and use |
| 01/02/2007 | US7157498 Diamines having a CaSR modulating activity |
| 12/27/2006 | EP1353928B1 Process for preparing clopidogrel |
| 12/21/2006 | WO2006105996A3 Process for the preparation of an optically active ester |
| 12/21/2006 | WO2006050002A3 Compositions for controlled delivery of pharmaceutically active compounds |
| 12/14/2006 | US20060281926 Synthesis of 2-alkylcysteine via phase transfer catalysis |
| 11/28/2006 | US7141694 Enzymatic resolution of aryl and thio-substituted acids |
| 11/08/2006 | EP1719758A1 Process for producing monatin |
| 11/02/2006 | US20060247458 Process for the production of optically active compounds having substituents at the 2-position |
| 10/12/2006 | WO2006105996A2 Process for the preparation of an optically active ester |
| 10/11/2006 | EP1710221A1 Process for the preparation of an optically active ester |
| 10/03/2006 | US7115769 Catalyzing the alkylation, forming a 2-alkylcysteine derivatives, a chemical intermediates for iron chelating agents |
| 09/28/2006 | US20060217561 Synthesis of substituted thiazoline carboxylic acids |
| 09/27/2006 | CN1276907C Splitting method of (R)-(-)-2-hydroxy-2-(2-chlorphenyl)acetic acid |
| 09/20/2006 | CN1275962C Novel anticholinergic agents that can be used as medicaments and method for the production thereof |
| 09/13/2006 | CN1274839C Process for preparation of enantiomerically enriched esters and alcohols |
| 07/27/2006 | US20060167267 Michael-type addition of a nucleophile to a dialkyl 2-methylidenylpropan-1,3-dioate and the conversion of a ester moiety into an amino moiety; S)-2-methylcysteine; desferrithiocin |
| 07/26/2006 | CN1266136C Kinetic resolution of intermediate for preparing benazepril and its analogues |
| 07/18/2006 | US7078226 Method for producing optically active amines |
| 06/29/2006 | US20060142586 Synthesis of 2-alkyl amino acids |
| 06/08/2006 | US20060122429 Preparation of optically active amines |
| 06/07/2006 | CN1784378A Method for the synthesis of 4-hydroxyisoleucine and the derivatives thereof |
| 05/24/2006 | CN1257149C Racemization of rotatory amine |
| 05/11/2006 | CA2580363A1 Compositions for controlled delivery of pharmaceutically active compounds |
| 05/10/2006 | EP1283898B1 Process for the preparation of enantiomerically enriched esters and alcohols |
| 05/04/2006 | WO2006046062A1 Process for the de-enrichment of enantiomerically enriched substrates |
| 05/04/2006 | WO2006046059A1 Catalyst compositions and their use in the de-enrichment of enantiomerically enriched substrates |
| 05/04/2006 | CA2583821A1 Process for the de-enrichment of enantiomerically enriched substrates |
| 05/04/2006 | CA2583489A1 Catalyst compositions and their use in the de-enrichment of enantiomerically enriched substrates |
| 05/02/2006 | US7038073 Synthesis of 2-alkyl amino acids |
| 04/25/2006 | US7034178 Reacting 3-phenylglycidic acid with ammonia; forming 3-phenylisoserine alkyl ester; separation of racemic mixture using tartaric acid |
| 04/11/2006 | US7026320 Serotonergic agents |
| 04/11/2006 | US7026143 Enzymatic resolution of aryl and thio-substituted acids |
| 03/30/2006 | US20060069265 Reacting cysteine (or a salt or an ester) and an aryl carboxylic acid to form a thiazoline ring; stereospecifically alkylating the thiazoline ring, and hydrolyzing the thiazoline ring to obtain a 2-alkylcysteine; chelation |
| 03/08/2006 | CN1244585C Synthesis of silicyl camptothecins and silicyl homo camptothecins |
| 02/21/2006 | US7002036 For production of (poly)peptides; comprises Michael-type addition of nucleophile to a dialkyl 2-methylidenylpropan-1,3-dioate and conversion of ester to amino moiety |
| 02/01/2006 | CN1239468C Method for the racemization of optically active amines |
| 01/04/2006 | CN1234679C Shortened synthesis of 3, 3-diaryl propylamine derivatives |
| 01/03/2006 | US6982335 Synthesis of substituted thiazoline carboxylic acids |
| 12/14/2005 | CN1231451C Process to enable recemation of optical rotary vinyl substituted cyclopropane carboxylic compound |
| 11/30/2005 | EP1600438A1 Processes for the production of optically active compounds having substituents at the 2-position |
| 11/17/2005 | US20050256172 1-(3-Pyridyl-2-(N-(2-(3,4-dichlorophenyl)ethyl-N-propylamino)ethanol and a dihydrobromide salt; ligands of sigma receptors; sterol Delta 7,8-isomerase inhibitors; anticholesterol agents; antilipemic agents; hypercholesterolemia and hyperlipemia; side effect reduction due to more targeted action |
| 11/16/2005 | EP1317426B1 Beta-thio-amino acids |
| 11/02/2005 | CN1690032A Thermal stable bromated bisphenol-a bis-dibromo- isobutyl ether |
| 11/02/2005 | CN1225452C Prepn. of (+)-trans-chrysanthemic acid |
| 09/22/2005 | US20050209462 Synthesis of benzimidate from benzoic acid |
| 09/14/2005 | CN1668594A New derivatives of pyridilethanol (phenylethyl) amines as cholesterol biosynthesis inhibitors, procedures of their preparation and pharmaceutical preparations which they contain |
| 09/09/2005 | WO2005082850A1 Process for producing monatin |
| 09/01/2005 | US20050192437 Process for the preparation of 6alpha-fluoro steroids by isomerisation of 6beta-fluorosteroids |
| 09/01/2005 | US20050192317 Novel diamines having a casr modulating activity |
| 06/29/2005 | EP1546105A1 Novel derivatives of pyridylethanol (phenylethyl) amines as inhibitors of cholesterol biosynthesis, processes for their preparation, and pharmaceutical compositions containing them |
| 06/21/2005 | US6909017 As a saccharinate from a mixture of the diastereomers (1SR,2)RS-2-((dimethylamino)methyl)-1-(3-methoxyphenyl)-cyclohexanol and (1SR-2RS)-2-((dimethylamino) methyl)-1-(3-methoxyphenyl)-cyclohexanol and impurities |
| 06/14/2005 | CA2197900C Racemization of optically active amines |
| 06/07/2005 | US6903220 Synthesis of chiral 2-alkyl amino acids |
| 06/01/2005 | CN1204262C Method for producing optically active amines |
| 05/17/2005 | US6894170 Process for the preparation of substituted thiazolines and their intermediates |
| 05/12/2005 | US20050101782 Process for the preparation of substituted thiazolines and their intermediates |