Patents
Patents for C07B 51 - Introduction of protecting groups or activating groups, not provided for in groups (403)
05/2003
05/22/2003WO2003041647A2 Synthesis and purification of valacyclovir
05/22/2003US20030097015 Protecting a functional group of an organic compound containing minimally two carbon atoms by reacting with silane compound
05/22/2003CA2649826A1 Synthesis and purification of valacyclovir
05/01/2003US20030082831 Apparatus for use in the synthesis of preferential biopolymers
04/2003
04/22/2003US6552223 N-hydroxacylamino compounds, process for their preparation and pharmaceutical compositions containing them
04/17/2003US20030073868 Non-C2-symmetric bisphosphine ligands as catalysts for asymmetric hydrogenation
04/16/2003EP1265684A4 Purification device and purification method
04/03/2003US20030064391 Preparation of sequences on substrate; obtain substrate, deposit on plate surface, incubate with activator, remove protective groups, recover biopolymer
04/02/2003EP1298134A1 Norbornyl-substituted silanes and their use in the protection of functional groups of organic compounds
03/2003
03/19/2003EP0946286B1 Chemical amplification for the synthesis of patterned arrays
03/06/2003WO2003018604A1 Synthesis of solanum glycosides
03/06/2003CA2458183A1 Synthesis of solanum glycosides
03/04/2003US6528678 Phosgene-free process for preparing carbamates
02/2003
02/19/2003EP1144360A4 A method for the synthesis of compounds of formula 1 and derivatives thereof
02/05/2003EP1280753A1 Process for preparation of r-1-(aryloxy)propan-2-ol
01/2003
01/16/2003US20030013100 Nucleic acid reading and analysis system
01/09/2003US20030008302 Sequencing of surface immobilized polymers utilizing microfluorescence detection
12/2002
12/19/2002WO2002100880A1 Method for preparing oestrogen derivatives
12/19/2002US20020192693 Apparatus for polymer synthesis
12/18/2002EP1265684A1 Purification device and purification method
12/12/2002WO2002098849A2 Hydroxy alkyl amine derivatives as beta-secretase inhibitors and their use for the treatment of alzheimer’s disease and similar diseases
12/12/2002CA2448834A1 Hydroxy alkyl amine derivatives as beta-secretase inhibitors and their use for the treatment of alzheimer's disease and similar diseases
12/10/2002US6491871 System for determining receptor-ligand binding affinity
10/2002
10/31/2002DE10147625C1 New 2-norbornylsilyl compounds used for protecting functional groups of organic compounds containing acid hydrogen, e.g. hydroxyl in alcohol or diols, comprises chloro or trifluoromethanesulfonate group and known analogues
10/03/2002US20020143214 Synthesis of non-C2-symmetric bisphosphine ligands as catalysts for asymmetric hydrogenation
09/2002
09/26/2002WO2002034698A3 Phosgene-free process for preparing carbamates
09/26/2002WO2001019484A9 Purification device and purification method
09/25/2002EP1243591A2 Synthesis of non-C2-symmetric bisphosphine ligands as catalysts for asymmetric hydrogenation
09/17/2002CA2278878C Very large scale immobilized peptide synthesis
09/10/2002US6448449 Process for preparation of (R)-1- (aryloxy)propan-2-ol
09/03/2002CA2178085C Glutaramide derivatives
08/2002
08/29/2002US20020120140 Phosgene-free process for preparing carbamates
08/28/2002EP1233970A2 Protecting groups useful in the synthesis of polysaccharides, natural products, and combinatorial libraries
07/2002
07/30/2002US6426421 Protecting groups useful in the synthesis of polysaccharides, natural products, and combinatorial libraries
07/25/2002WO2002057269A1 Synthesis of temozolomide and analogs
07/18/2002US20020095036 Synthesis of temozolomide and analogs
07/11/2002US20020091269 Synthesis of epothilones and related analogs
06/2002
06/11/2002US6403957 Nucleic acid reading and analysis system
06/06/2002WO2002044132A1 A process for the preparation of iopamidol and the new intermediates therein
05/2002
05/30/2002US20020064796 Generating preferential amino acid sequences on substrate; obtain substrate, deblock, expose to amino acids, recover preferential particles
05/02/2002WO2002034698A2 Phosgene-free process for preparing carbamates
05/02/2002CA2426466A1 Phosgene-free process for preparing carbamates
04/2002
04/18/2002WO2002030356A2 Synthesis of epothilones and relates analogs
04/18/2002CA2425828A1 Synthesis of epothilones and related analogs
01/2002
01/17/2002US20020007090 Ring opening of (R)-propylene oxide with aryltrimethylsilyl ether in the presence of an optically active catalyst; reacting with an alcohol in the presence of an acid; reacting the regioisomeric mixture with a triarylmethyl halile;
01/09/2002EP0693052B1 Deallylation reagent and deallylation method using said reagent
12/2001
12/11/2001US6329143 Providing a substrate having surface bearing multiple copies of a protective group removable on exposure to an electric field or electric current; applying electric field or current to substrate; exposing to protected monomer, repeating
12/04/2001CA2278883C Very large scale immobilized peptide synthesis
11/2001
11/01/2001WO2001081286A1 Process for preparation of r-1-(aryloxy)propan-2-ol
11/01/2001US20010036629 Sequencing of surface immobilized polymers utilizing microfluorescence detection
11/01/2001CA2406215A1 Process for preparation of r-1-(aryloxy)propan-2-ol
10/2001
10/17/2001EP1144360A1 A method for the synthesis of compounds of formula 1 and derivatives thereof
09/2001
09/18/2001US6291183 A plurality of oligonucleotide linker molecules are attached on a planar solid support, photoremovable groups react with terminal ends of oligonucleotides, substrates exposed to light activate binding at selected areas; peptide synthesis
09/07/2001WO2001038337A3 Protecting groups useful in the synthesis of polysaccharides, natural products, and combinatorial libraries
08/2001
08/28/2001CA2054706C Very large scale immobilized polymer synthesis
07/2001
07/18/2001CN1068586C Crystalline polymorphic form of (S.S.S)-N-(1-[2-carboxy-3-(N2-mesyllysylamino)propyl]-1-cyclopenlylcarbonyl) throsine
07/17/2001US6261776 Nucleic acid arrays
06/2001
06/27/2001EP1109777A1 N-hydroxyacylamino compounds, process for their preparation and pharmaceutical compositions containing them
05/2001
05/31/2001WO2001038337A2 Protecting groups useful in the synthesis of polysaccharides, natural products, and combinatorial libraries
05/31/2001CA2391966A1 Protecting groups useful in the synthesis of polysaccharides, natural products, and combinatorial libraries
05/01/2001US6225625 Signal detection methods and apparatus
03/2001
03/22/2001WO2001019484A1 Purification device and purification method
03/22/2001CA2388747A1 Purification device and purification method
01/2001
01/30/2001US6180665 Crystalline polymorphic form of (S,S,S)-N-(1-[2-carboxy-3 (N2-mesyllyslamino) propyl]-1- cyclopentylcarbonyl) tyrosine
01/10/2001CN1279665A Method for functionalizing phenolic compound bearing electron-donor group
12/2000
12/05/2000US6156889 Reagent useful for cleaving a protected functional group
11/2000
11/21/2000US6150548 Linkers
08/2000
08/16/2000EP1027326A1 Method for functionalizing a phenolic compound bearing an electron-donor group
08/03/2000DE19903268A1 Verfahren zur Decarbamoylierung von N-carbamoylgeschützten Verbindungen, neue Carbonsäureanhydride und deren Verwendung Method for decarbamoylation of N-carbamoylgeschützten connections, new carboxylic anhydrides and their use
08/02/2000EP1024133A2 Process for the decarbamoylation of N-carbamoyl-protected compounds, new carboxylic anhydrides and their use
07/2000
07/27/2000WO2000043352A1 A method for the synthesis of compounds of formula 1 and derivatives thereof
07/27/2000CA2359076A1 A method for the synthesis of compounds of formula 1 and derivatives thereof
07/04/2000US6083697 Chemical amplification for the synthesis of patterned arrays
03/2000
03/09/2000WO2000012467A1 N-hydroxyacylamino compounds, process for their preparation and pharmaceutical compositions containing them
11/1999
11/03/1999EP0953835A1 Apparatus for detection of a fluorescence pattern corresponding to ligand binding on a substrate
10/1999
10/06/1999EP0946286A1 Chemical amplification for the synthesis of patterned arrays
08/1999
08/31/1999US5945524 Nucleoside with dansylethoxycarbonyl group as base-labile 5'-hydroxyl protective group; for efficient synthesis
08/13/1999CA2260736A1 Linkers
05/1999
05/11/1999US5902723 Selectively removing a nucleotide by cleavage at terminal ends with catalytic antibodies; identifying excision site and repeating process; for concurrent parallel sequence analysis
04/1999
04/21/1999EP0565607B1 Protection group, compoud protected by this group and device for grafting the protection group onto the compound being protected
04/15/1999WO1999018064A1 Method for functionalizing a phenolic compound bearing an electron-donor group
03/1999
03/17/1999EP0902034A2 Very large scale immobilized peptide synthesis
01/1999
01/13/1999EP0731787B1 Crystalline, polymorphic form of (s,s,s)-n-(1-[2-carboxy-3-(n2-mesyllysylamino)propyl]-1-cyclopentylcarbonyl)tyrosine
12/1998
12/08/1998US5847117 Reagent and catalytic process useful for cleaving a protected functional group
09/1998
09/15/1998CA2036962C Process for the desilylation of a 4-silyloxy-tetrahydro-pyran-2-one
06/1998
06/30/1998US5773617 Deallylation reagent and deallylation method using said reagent
05/1998
05/22/1998WO1998020967A1 Chemical amplification for the synthesis of patterned arrays
07/1997
07/22/1997US5650523 Process for the desilylation of a 4-silyloxy-tetrahydro-pyran-2-one
05/1997
05/20/1997US5631362 Forming dna and rna by polycondensation of mononucleotides with protective sulfonylalkyl dimethylaminonaphthalene groups for alkoxy furan groups
04/1997
04/29/1997US5625046 Hydroxyl projecting groups for organic synthesis
03/1997
03/12/1997EP0583338B1 Method for synthesizing peptides, novel amino acid derivatives used therein, and methods for preparing same
03/11/1997US5610275 Reagent useful for cleaving and process for using this reagent
02/1997
02/12/1997CN1142816A Crystalline, polymorphic form of (S,S,S)-n-(1-|2-carboxy-3-(n2-mesyllysylamino)propyl¨-1-cyclopenlylcarbonyl)tyrosine
09/1996
09/18/1996EP0731787A1 Crystalline, polymorphic form of (s,s,s)-n-(1- 2-carboxy-3-(n?2 -mesyllysylamino)propyl]-1-cyclopentylcarbonyl)tyrosine
08/1996
08/20/1996US5547839 Contacting polynucleotides with surface of solid substrate, hybridizing using nucleic acid polymerase and labeled nucleotide
05/1996
05/15/1996CN1122594A Deallylation reagent and deallylation method using said reagent
04/1996
04/23/1996US5510270 Generating pattern of light and dark areas by selectively irradiating surface areas; deprotecting; contacting with receptor to identify oligonucleotide showing complementarity to receptor
01/1996
01/30/1996US5488172 Chiral phosphorus compounds
01/24/1996EP0693052A1 Deallylation reagent and deallylation method using said reagent
08/1995
08/29/1995US5445934 Selective photoremovable groups on surface
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