Patents
Patents for A61P 7 - Drugs for disorders of the blood or the extracellular fluid (67,065)
07/1988
07/12/1988US4757057 Antithrombotic agents
07/06/1988EP0273800A2 Hirudine variants, their use and preparation
07/06/1988EP0273645A2 Novel derivatives of arginine vasopressin antagonists
07/06/1988EP0273253A2 Use of 6-allyl-2-amino-5,6,7,8-tetrahydro-4H-thiazolo-[5,4d]azepine in the release of a somatotropic hormone
07/05/1988US4755514 Phenylpyrazine derivatives and thrombolytic agent
07/05/1988US4755512 Pharmaceutically useful dihydropyridinyldicarboxylate amides and esters incorporating arylpiperazinylalkyl moities
07/05/1988CA1238908A1 2-aminomethylphenol derivatives, a process for their preparation, their use, and pharmaceutical formulations based on these compounds
06/1988
06/30/1988WO1988004690A1 New plasminogen activators
06/29/1988EP0272982A2 Indane derivatives, process for their preparation and intermediates obtained, their use as medicines and compositions containing them
06/29/1988EP0272703A1 Novel polypeptide
06/29/1988EP0272304A1 A process for producing a coagulation active complex of factor viii fragments.
06/28/1988US4753936 Circulation-active substituted 1,4-dihydropyridine-3-carboxylic acid piperazides
06/22/1988EP0271885A2 Medicine containing the tissular protein PP4, process for the preparation of PP4 and its pasteurization, and the use of PP4
06/22/1988CN87107427A Substituted aminomethyl-5,6,7,8-tetrahydronaphthloxy-acetic acids, intermed iate products, processes for their preparation and their use in medicaments
06/21/1988US4752616 Arylthioalkylphenyl carboxylic acids, compositions containing same and method of use
06/21/1988US4752613 Thromboxane a2 receptor antagonists
06/21/1988US4752603 Immunologically distinct from urokinase
06/21/1988CA1238318A1 Double salt, process for its preparation and pharmaceutical composition containing it
06/21/1988CA1238314A1 Process for preparing basic heptapeptide vasopressin antagonists
06/16/1988WO1988004180A1 Improvements in or relating to the use of epidermal growth factor
06/16/1988DE3740595A1 Neue prostacycline New prostacyclins
06/15/1988EP0271227A2 Recombinant hybrid immunoglobulin molecules and their use
06/15/1988EP0271059A1 2-Methylthiomethyl-dihydropyridines, a process for their preparation and pharmaceutical compositions containing them
06/15/1988EP0271040A2 Pyrrolobenzimidazoles, process for their preparation, and medicaments
06/15/1988EP0270929A2 Substituted aminomethyl-5,6,7,8-tetrahydronaphthyl-oxy-acetic acids, intermediate products, process for their preparation and their use in pharmaceuticals
06/15/1988CN87105263A Polyhydroxylated and highly fluorinated compounds, their preparation and their use as surfactants
06/14/1988US4751228 Cardiovascular disorders
06/14/1988US4751227 3-cyano-5-(6-imidazo[1,2-a]pyridyl)pyridin-2-ols useful as cardiotonics
06/08/1988EP0270516A2 Process for the preparation of a fraction containing factor VIII (AHF)
06/08/1988EP0270460A2 Microcrystals containing an active substance with a phospholipid affinity and at least a phospholipid; preparation process
06/08/1988EP0270413A1 Process for the preparation of factor VIII
06/08/1988EP0270371A2 Vasopressin antagonists
06/08/1988EP0270214A2 Vasopressin antagonists
06/07/1988US4749783 Viral inactivation and purification of active proteins
06/07/1988US4749782 Treating congestive heart failure, hypertension
06/07/1988US4749780 Biologically active fragments of human antihemophilic factor and method for preparation thereof
06/07/1988US4749715 7-oxabicycloheptane substituted amino prostaglandin analogs
06/02/1988WO1988003808A1 Method for treating iron overload
06/01/1988EP0269394A2 Method for treating iron overload
06/01/1988EP0269299A2 Atrial peptides
06/01/1988EP0269220A2 Derivatives of alpha-hANP and their production
06/01/1988EP0269105A2 Derivatives of cyclohexane, preparations containing them and their use
06/01/1988EP0268800A1 Phenoxyacetic acid derivatives and processes for preparing the same
06/01/1988EP0268772A2 Expression of biologically active factor XIII
06/01/1988EP0268581A1 Prostacyclines, their analogues or prostaglandines and thromboxane antagonists for the treatment of thrombotic and thrombo-embolic illnesses.
05/1988
05/31/1988US4748232 Peptide production and use thereof
05/31/1988US4748155 Pharmacologically active tripeptides and process for their synthesis
05/25/1988EP0268178A1 Pyrrolo-benzimidazoles, medicaments containing these compounds and process for their preparation
05/25/1988EP0267986A1 "(2-amino-4-aryl-thiazole-5-yl)ethanols and their derivatives having diuretic activity and methods for preparing the same
05/24/1988US4746730 Bio-available iron-protein derivatives and process for their preparation
05/24/1988US4746729 Cartilage-derived leukocyte elastase-inhibitor
05/24/1988US4746676 Carboxyalkyl dipeptide compounds
05/24/1988US4746671 Pharmaceutical use of [[[(3-pyridinyl)methylen]amino]oxy]alkanoic acids and esters
05/24/1988US4746668 2-(2-phenyl-2-(2-pyridyl)ethyl-2-imidazoline
05/24/1988US4746664 Substituted-3,4-dihydro-4-(2,4,6-trimethoxyphenylimino)-2(1H)-pyrimidones useful as cardiotonic, antihypertensive, cerebrovascular vasodilator and anti-platelet agent
05/24/1988US4746660 Process for reducing reflex tachycardia in the treatment of hypertension employing a combination of a diazacyclopentene derivative and a pyridazinone derivative
05/19/1988WO1988003559A1 Recombinant hybrid immunoglobulin molecules and method of use
05/19/1988WO1988003537A1 Novel peptides
05/19/1988WO1988003535A1 Peptide compounds
05/19/1988WO1988003408A1 Extra pure semi-synthetic blood substitute
05/18/1988EP0267878A1 N9-cyclopentyl-substituted adenine derivatives
05/18/1988EP0267741A1 Peptide compounds
05/18/1988EP0267439A2 Alpha-(phenylalkyl) pyridinealkanol derivatives
05/17/1988US4745198 1,3-dioxan-5-ylalkenoic acids
05/17/1988US4745177 Anticoagulants, polypeptides
05/17/1988US4745099 Pharmaceutical composition for the treatment of the anemia of malignant tumors
05/17/1988CA1236786A1 Peptide compounds
05/11/1988EP0267155A2 Bicyclic compounds
05/11/1988EP0266993A2 Method and therapeutic compositions for the treatment of bleeding disorders
05/11/1988EP0266980A2 Pharmaceutical compositions, comprising a 2,4-diphenyl-1,3-dioxane derivative and an inhibitor of thromboxane A2 synthesis
05/11/1988EP0266979A2 Therapeutic agents
05/11/1988EP0266949A1 Tetrahydroisoquinolin-2-yl derivatives of carboxylic acids as thromboxane A2 antagonists
05/11/1988EP0266922A1 Dihydropyridine derivatives, their preparation and their use
05/11/1988EP0266558A2 5-Alkylbenzimidazoles, process for their preparation and medicaments containing them
05/10/1988US4743693 Process for the preparation of a stable modification of torasemide
05/10/1988US4743613 Ester prodrugs of dopamine-β-hydroxylase, inhibitors, composition containing them, and method of using them to inhibit dopamine-β-hydroxylase activity
05/05/1988WO1988003137A1 Tetrahydroisoquinolin-2-yl derivatives of carboxylic acids as thromboxane a2 antagonists
05/05/1988WO1988003027A1 Hemolysis inhibitor and medical resin composition, medical implement, and blood-preserving fluid containing the same
05/04/1988EP0266006A2 Novel hypotensive diuretic peptides
05/04/1988EP0265947A2 Dihydropyridine derivatives, process for their preparation, pharmaceutical composition and use
05/04/1988CN87107150A Dihydropyridine derivatives, their preparation and their use
05/04/1988CN87104319A 苯并吡喃衍生物 Benzopyran derivatives
05/03/1988US4742058 Polyprenyl compound, process for the production thereof and drug containing the same
05/03/1988US4741903 Novel enzyne derivatives
05/03/1988CA1236014A1 Polysaccharide haemoglobin complexes
04/1988
04/27/1988EP0265129A1 Thrombolytic therapy
04/27/1988EP0265082A1 Apparatus and process for oxygenation of liquid state dissolved oxygen-carrying formulation
04/27/1988EP0098794B1 Carbacyclines, process for their preparation and their use as medicines
04/26/1988US4740594 Dextran derivatives endowed, particularly with anti-coagulant properties and anti-complementary properties, their preparation and their biological uses
04/26/1988US4740523 Interfuranylene prostacyclins
04/26/1988US4740510 Derivatives of alpha-(2-oxo 2,4,5,6,7,7a-hexahydro thieno[3,2-c]5-pyridyl) phenyl acetic acid, and their use as platelet and thrombotic aggregation inhibitors
04/20/1988EP0264232A1 2-Azetidinone derivatives
04/20/1988EP0264231A1 Azetidinone derivatives
04/20/1988EP0264114A1 Alpha-[(phenylmethoxy)methyl]pyridine-alkanol derivatives
04/20/1988EP0264060A2 Anticoagulating substance and preparation process thereof
04/20/1988CN87106895A Phenoxyacetic acid derivative and processes for preparing same
04/19/1988US4739050 Calcium antagonist, anticoagulant
04/19/1988US4739039 Method for preparing antihemophilic factor (AHF) by cold precipitation and for improving solubility of recovered AHF product
04/19/1988US4738979 Adrenergic receptors; anti-convulsive drug; treatment of metabolic and neutral disorders
04/19/1988US4738954 Hypotensive agents, analgesics, nervous system disorders