Patents
Patents for A61P 7 - Drugs for disorders of the blood or the extracellular fluid (67,065)
12/1988
12/13/1988CA1246575A1 Pyrazolopyridine derivatives, therapeutic compositions comprising same, and process thereof
12/13/1988CA1246558A1 Carbacyclin amides, process for their manufacture and their use as medicaments
12/08/1988DE3717232A1 Process for the preparation of 7H-1,3,4-thiadiazolo[3,2-a]pyrimidines substituted in the 2-position by amine-containing groups
12/07/1988EP0294025A2 Peptides corresponding to the Factor VIII binding domain of the von Willebrand factor
12/07/1988EP0294016A2 Factor XIIIa inhibitor compounds useful for thrombolytic therapy
12/07/1988EP0293936A2 Tissue plasminogen activator analogs having modified growth factor domains
12/07/1988EP0293934A1 Mutant t-PA with kringle replacement
12/07/1988EP0293881A2 Peptide boronic acid inhibitors of trypsin-like proteases
12/07/1988EP0293716A2 Polyhydrobenz(c,d)indolsulfonamides
12/07/1988EP0293567A1 Vascular anticoagulating proteins, DNA encoding them, process for their production and their use
12/07/1988EP0293500A1 3-heteroalkyl-2,4.quinzaoline-diones
12/06/1988US4789733 Purification of blood coagulation factor VIII by precipitation with sulfated polysaccharides
12/06/1988CA1246081A1 1-phenyl-containing substituent-4-amino-pyrimidine compounds
12/01/1988WO1988009376A1 Method and compositions for making acsf and acsf antagonists
12/01/1988WO1988009347A1 Novel heparin derivatives
12/01/1988WO1988009346A1 Haemoglobin complexes
12/01/1988WO1988009333A1 Thieno(triazolo)diazepine compound and medicinal application of the same
12/01/1988WO1988009179A1 Blood substitutes
11/1988
11/30/1988EP0293171A1 Pyrazinamide derivatives
11/30/1988EP0293170A1 Aminomethylphenolic pyrazines, their preparation and use
11/30/1988EP0293078A1 Pharmaceutically active amines
11/30/1988EP0292908A1 Protein absorption enhancing agents
11/30/1988EP0292846A2 A process for the extraction of docosahexaenoic acid ethyl ester from fish oils and pharmaceutical and/or dietetic compositions containing a mixture of docosahexaenoic and eicosapentaenoic acid ethyl esters
11/30/1988EP0292643A1 Prostaglandin E1 derivatives and their therapeutical application
11/29/1988US4788281 Dextran hexonic acid derivative, ferric hydroxide complex and method manufacture thereof
11/29/1988US4788206 Pentadieneamides
11/29/1988US4788200 Method and composition for treating arteriosclerosis
11/29/1988US4788197 Anticoagulants
11/29/1988CA1245661A1 2-aminomethyl-6-sulfamoylphenol derivatives, a process for their preparation and their use and also pharmaceutical formulations based on these compounds
11/29/1988CA1245646A1 Carbacyclins, process for their manufacture and their use as medicaments
11/29/1988CA1245637A1 Peptide, and production and use thereof
11/29/1988CA1245636A1 Diuretic peptide, and production and use thereof
11/29/1988CA1245635A1 .alpha.-HUMAN ATRIAL NATRIURETIC POLYPEPTIDE AND PHARMACEUTICAL USE THEREOF
11/29/1988CA1245589A1 Indanyl derivatives and process for their preparation
11/29/1988CA1245559A1 Cardiovascular composition
11/23/1988EP0292326A2 Modified enzyme
11/23/1988EP0292273A2 Vasopressin antagonists
11/23/1988EP0292257A2 Peptides having ANF activity
11/23/1988EP0292256A2 Peptides having ANF activity
11/23/1988EP0292003A2 Stabilzation of biological and pharmaceutical products during inactivation of viral and bacterial contaminants
11/23/1988EP0291982A2 Cyclic anticoagulant peptides
11/23/1988EP0291981A2 Cyclic anticoagulant peptides
11/23/1988EP0291594A1 Pyrazine for use in the treatment of haemodynamic and metabolic disorders
11/23/1988CN88102511A 吡咯烷衍生物 Pyrrolidine derivative
11/22/1988US4786645 Antiallergens, antiinflammatory
11/17/1988EP0291270A2 Improvements in or relating to ergoline derivatives
11/17/1988EP0291234A2 Peptidic human leukocyte elastase (HLE) inhibitors
11/17/1988EP0290675A1 Allenic prostacyclins
11/17/1988DE3815213A1 Neue derivate des forskolins sowie ihre herstellung und pharmazeutische verwendung New derivatives of forskolin as well as their production and pharmaceutical use
11/15/1988US4785018 Glycine derivatives
11/15/1988US4784950 Cloning, genetic engineering
11/15/1988CA1244763A1 Blood coagulation inhibiting proteins, processes for preparing them and their uses
11/09/1988EP0290321A1 Beta-D-phenyl-thioxylosides, process for their preparation and their use in therapy
11/09/1988EP0290261A1 Expression of foreign genes in drosophila cells
11/09/1988EP0290252A2 Pasteurizable, freeze-driable hemoglobin-based blood substitute
11/09/1988EP0290211A1 Dihydropyridines
11/09/1988EP0290118A2 Fibrinolytically active enzyme
11/09/1988EP0289911A2 Pyrrolidine derivatives
11/09/1988CN88101370A Pharmaceutical compositions for treating cardiovascular system and process for preparing same
11/09/1988CN88100260A Anticoagulant peptides
11/08/1988US4783480 6-keto-prostaglandin E1 derivatives
11/08/1988US4783476 3-Phenoxy (or phenylthio)-cyclopentanecarbonylamino acid analogues
11/08/1988US4783473 Geminally substituted cyclic ether carboxylic acids, derivatives thereof, compositions containing same and method of use
11/08/1988US4783472 1H,3H-pyrrol[1,2-c]thiazole derivatives and pharmaceutical compositions containing them
11/08/1988US4783447 Process for producing natural heparan sulphate and dermatan sulphate in substantially pure form, and their pharmaceutical use
11/08/1988CA1244436A1 4-quinolone derivatives
11/08/1988CA1244432A1 Derivative of dihydroxybenzamide
11/08/1988CA1244419A1 Substituted pyridazinones, processes for producing them, pharmaceutical preparations containing these compounds, and the use thereof
11/08/1988CA1244407A1 Atrial peptide having useful natriuretic, diuretic and vasodilating activity
11/07/1988EP0275305A4 Dna sequences coding for modified factor viii:c and modified factor viii:c-like polypeptides and processes for producing these polypeptides in high yields.
11/03/1988WO1988008451A1 HUMAN t-PA(u-PA) SUBSTITUTION-MUTANT PROTEINS, RECOMBINANT DNA CODING THEREFOR, TRANSFECTED HOST CELLS, PREPARATION OF THE MUTANT PROTEINS, AND PHARMACEUTICAL COMPOSITIONS
11/03/1988WO1988008444A1 Process for preparing oil composition
11/03/1988WO1988008424A1 Pharmaceutically active amines
11/03/1988DE3809225A1 Arzneimittel, geeignet zur vorbeugung gegen beziehungsweise behandlung von erkrankungen des herz/kreislauf-systemes Medicines suitable for prevention or treatment of diseases against the heart / circulatory-systemes
11/02/1988EP0289227A1 Substituted imidazolyl-alkyl-piperazine and -diazepine derivatives
11/02/1988CN88102191A Piperidine opioid antagonists
11/01/1988US4782089 Antiinflammatory, analgesic
11/01/1988US4782088 Hypotensive, antithrombotic
11/01/1988US4782069 Inhibition of platelet activation
11/01/1988US4782063 Ergoline esters useful as serotonin antagonists
11/01/1988US4782057 Benzo[h]cinnoline compound, a method of preparing said compound and a pharmaceutical composition
10/1988
10/26/1988EP0288435A1 Process for the production of proteins
10/26/1988EP0288279A2 1,3-Dioxanes
10/26/1988EP0288196A1 Sulfonyldecahydro-8H-isoquino[2,1-g][1,6]naphthyridines, optical isomers thereof and related compounds
10/26/1988EP0287866A1 Substituted 1,4-dihydropyridines, method for their preparation and their use
10/26/1988EP0287696A1 Isoquinoline derivatives
10/26/1988CN88101200A Process for preparing optically active oxo-isoindolinyl derivatives
10/25/1988US4780474 Use of alkylenediamine derivatives for the treatment of blood flow disturbances and pharmaceutical compositions containing them
10/25/1988US4780456 Pharmaceutical or dietetic composition having a high antiarteriosclerotic activity
10/25/1988CA1243606A1 Pharmaceutical compositions containing iron complexes of 3-hydroxy-4-pyrones
10/19/1988EP0287339A2 Piperidine opioid antagonists
10/19/1988EP0287270A1 Biologically active compounds
10/18/1988US4778817 Naphthyl imidazolyl compounds and pharmaceutical compositions
10/18/1988US4778804 Anticoagulants, hypotensive agents
10/18/1988US4778796 ω-(3-pyridyl)alkenamide derivatives and anti-allergenic pharmaceutical compositions containing same
10/18/1988US4778792 Use of 7-acyl benzoxazinones and their derivatives in treating atheromatous disorders
10/18/1988CA1243326A1 Dibenz¬be|oxepinacetic acid derivatives, the preparation thereof and their application in therapy
10/18/1988CA1243323A1 1,3-benzoxathiole derivatives, their use and their preparation
10/18/1988CA1243314A1 2-arylimidazopyridines and 8-arylpurines
10/18/1988CA1243313A2 Prostaglandins