Patents for A61P 25 - Drugs for disorders of the nervous system (183,225)
05/2008
05/02/2008WO2008050673A1 Adhesive skin patch
05/02/2008WO2008050600A1 Therapeutic or preventive agent for intractable disease based on oxidative stress-mediated cell death as molecular background
05/02/2008WO2008050200A1 Oxadiazole compounds as calcium channel antagonists
05/02/2008WO2008049997A2 Indole derivatives, process for the preparation thereof and pharmaceutical compositions containing them
05/02/2008WO2008049996A2 Novel indole derivatives, process for the preparation thereof and pharmaceutical compositions containing them
05/02/2008WO2008049994A1 New fluorene derivatives, compositions containing the same and use thereof as inhibitors of the protein chaperone hsp 90
05/02/2008WO2008049864A1 Oxadiazole and thiadiazole compounds and their use as nicotinic acetylcholine receptor modulators
05/02/2008WO2008049785A1 Ih channel inhibitors for the promotion of wakefulness
05/02/2008WO2008049226A1 Inhibition of sox9 function fn the treatment of proteogl ycan-associated pathophysiological conditions
05/02/2008WO2008049157A1 Combination therapy
05/02/2008WO2008019971A3 Arylpiperazine derivatives and uses thereof
05/02/2008WO2008002946A3 Method of modulating neurite outgrowth by the use of a galanin-3 receptor antagonist
05/02/2008WO2007150010A3 Cyclopropyl amine derivatives as histamin h3 receptor modulators
05/02/2008WO2007147892A3 Use of inducer of promyelocytic leukemia protein (pml) for treating polyglutamine expansion neurodegenerative diseases
05/02/2008WO2007061868A3 Treatment of stereotypic, self-injurious and compulsive behaviors using specific serotonin reuptake inhibitors and antagonists of nmda receptors
05/02/2008CA2667582A1 Method of treating conditions associated with proteoglycan production
05/02/2008CA2667553A1 Methods and combination therapies for treating alzheimer's disease
05/02/2008CA2667545A1 Oxadiazole and thiadiazole compounds and their use as nicotinic acetylcholine receptor modulators
05/02/2008CA2667536A1 Highly purified type a botulinum toxin preparation from infant botulism pathogen
05/02/2008CA2667397A1 Oleanane triterpene saponin compounds which are effective on treatment of dementia and mild cognitive impairment (mci), and improvement of cognitive function
05/02/2008CA2667260A1 Intracerebral oxidation inhibitor and use thereof
05/02/2008CA2667231A1 Process for selectively localizing active ingredients on and in mitochondria and corresponding active ingredients
05/02/2008CA2667052A1 Combination therapy
05/02/2008CA2666606A1 Preventing or reducing oxidative stress or oxidative cell injury by the administration of a water-insoluble cellulose derivative
05/02/2008CA2666497A1 Novel indole derivatives, process for the preparation thereof and pharmaceutical compositions containing them
05/02/2008CA2665710A1 Ih channel inhibitors for the promotion of wakefulness
05/02/2008CA2664115A1 New fluorene derivatives, compositions containing the same and use thereof as inhibitors of the protein chaperone hsp 90
05/01/2008US20080103306 preparation of an imidazole derivative of formula I,** Image-1wherein R1, R2, R3 and R4 are described hereinabove. These compounds can be used in the treatment or prevention of mGluR5 receptor mediated disorders. and treatment of pain, psychosis and memory deficits
05/01/2008US20080103213 Curcumin analog or metabolite microencapsulated by a polyethylene glycolated liposome of dimyristoyl phosphatidylcholine, cholesterol, and dimyristoyl phsphatidylethanolamine; anticarcinogenic agents; parenteral colloidal drug delivery system providing improved bioavailability
05/01/2008US20080103209 Compounds And Methods For Treating Non-Inflammatory Pain Using Ppar Alpha Agonists
05/01/2008US20080103200 Levodopa prodrugs, and compositions and uses thereof
05/01/2008US20080103197 Alkyl-, alkenyl- and alkynylcarbamate derivatives, their preparation and their application in therapeutics
05/01/2008US20080103196 19-hydroxylabda-8(17)-en-16,15-olide; mushroom extraction; MTT assay; neuroprotectant; cortical neuron damages, Alzheimer's disease; analgesic, antiinflammatory,anticarcinogenic, hypotensive agent
05/01/2008US20080103191 Entacapone-derivatives
05/01/2008US20080103189 Preparation and utility of substituted indoles
05/01/2008US20080103188 Novel bicyclic compounds as modulators of androgen receptor function
05/01/2008US20080103180 CCR9 inhibitors and methods of use thereof
05/01/2008US20080103179 For treating diabetes, hypertension, migraine, epilepsy, sleep apnea, depression, impulse control disorders or alcohol addiction; coadministering a sympathomimetic agent such as phentermine and an anticonvulsant sulfamate or sulfonylurea, preferably topiramate or zonisamide; side effect reduction
05/01/2008US20080103178 N-dihydroxyalkyl-substituted 2-oxo-imidazole derivatives
05/01/2008US20080103177 New use of iloperidone
05/01/2008US20080103176 N-{1-(3,5-Difluoro-benzyl)-3-[7-(2,2-dimethyl-propyl)-2-piperidin-1-yl-1,2,3,4-tetrahydro-naphthalen-1-ylamino]-2-hydroxy-propyl}-acetamide; 13-secretase inhibitor; Alzheimer's disease; inhibitors of beta-secretase, that inhibit beta-secretase-mediated cleavage of amiloid precursor protein APP
05/01/2008US20080103173 Compounds Having Activity At Nk3 Receptor And Uses Thereof In Medicine
05/01/2008US20080103172 as tyrosine, serine/threonine, cyclin-dependent kinases, HER protein; 5-{2-[3-[4-trifluoromethyl-1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazol-2-yl]-1-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrazol-4-yl]-vinyl}-pyridine-3-carbaldehyde; antiproliferative, antiinflammatory agent, neurodegenerative diseases
05/01/2008US20080103170 Nicotinic Acetylcholine Receptor Ligands
05/01/2008US20080103166 Administering tropisetron to prevent and treat Schizophrenia, Alzheimer's, Parkinson's, and Huntington's Diseases,Tourette's Syndrome and Attention deficit disorder; antidepressants, anxiolytic and antiepileptic agents
05/01/2008US20080103159 Composition Comprising Ocaperidone
05/01/2008US20080103158 Methods for treating delaying the progression of alzheimer's disease with heterocyclic compounds
05/01/2008US20080103157 3,3-dibenzylimidazo[1,2-a]pyridin-2(3H)-one; antidepressant, neuroprotectant, antiaging agent; manic depressive psychoses, obsessive-compulsive disorder; orally
05/01/2008US20080103154 3, 4-dihydro-2(IH)-quinolinone and 2(1H)-quinolinone derivatives
05/01/2008US20080103147 Highly selective norepinephrine reuptake inhibitors and methods of using the same
05/01/2008US20080103146 Highly Selective Norepinephrine Reuptake Inhibitors And Methods Of Using The Same
05/01/2008US20080103145 Administering racemic reboxetine component
05/01/2008US20080103142 c-Jun N-terminal kinase and cyclin-dependent kinase inhibitor; (4-benzotriazol-1-yl-5-chloro-pyrimidin-2-yl)-cyclohexyl-amine; antiinflammatory and anticarcinogenic agent; autoimmune and neurodegenerative disorders; rheumatoid arthritis, asthma, type II diabetes, Alzheimer's and Parkinson's diseases
05/01/2008US20080103137 antiinflammatory agents; 1H-imidazo[4,5-b]pyridin-7-indole-2-yl- derivatives; autoimmune and proliferative disorders; inhibitors of cell adhesion molecule expression and inflammatory cytokine signal transduction; rheumatoid arthritis, ulcerative colitis/Crohn's disease, central nervous system diseases
05/01/2008US20080103135 Histamine H3 antagonists; do not contain imidazolyl moiety; such as 1-[4-(4-piperidin-1-ylmethyl-phenyl)-but-3-ynyl]-piperidine
05/01/2008US20080103134 Use of selected CGRP-antagonists in combination with other antimigraine drugs for the treatment of migraine
05/01/2008US20080103133 4-OXO-2,3,4,5-TETRAHYDRO-BENZO[b][1,4]DIAZEPINE DERIVATIVES
05/01/2008US20080103132 Fused heterocyclic compounds
05/01/2008US20080103131 Therapeutically Active Thiophenepyrimidinone Compounds and Their Use
05/01/2008US20080103129 Heterocyclic derived metalloprotease inhibitors
05/01/2008US20080103128 Lactams substituted by cyclic succinates as inhibitors of abetta protein production
05/01/2008US20080103127 Methods for treating disruptive behavior disorders
05/01/2008US20080103126 2-[[3-(2-benzo[b]thiophen-5-yl-ethoxy)propyl](methyl)amino]-1-ethanol; antihypoxic agent; synergistic mixture with acetylcholine esterase inhibitor (Tacrine, Donepezil, Rivastigmine); neurodegenerative diseases, ischemic cerebral lesion, cerebral apoplexy, Alzheimer's disease, cognition activator
05/01/2008US20080103110 Water soluble prodrugs comprising therapeutics coupled via metabolically cleavable ester bond to proteins; extended blood half life; cancer, inflammation, infection, pain
05/01/2008US20080103107 Screening Methods
05/01/2008US20080103105 Nervous system, neurodegenerative, and psychological disorders are treated using synergistic mixture of neurogenic agents; atorvastatin, cerivastatin, fluvastatin, simvastatin, lovastatin, pravastatin, rosuvastatin, or crilvastatin; and buspirone, ribavirin, tacrine, azakenpaullone, or folic acid
05/01/2008US20080103102 Therapeutic compositions and methods of treatment with capsianoside-type compounds
05/01/2008US20080102121 exhibit a bimodal or multimodal release profile; solid oral dosage forms
05/01/2008US20080102090 Mixture with surfactant; therapy for muscular paralysis; greater intramuscular safety margin; selective action on inhibition of pain-related (nociceptive) nerve cell function
05/01/2008US20080102060 Methods of using bcl-2 for the therapeutic treatment and prevention of diseases
05/01/2008US20080102055 Method for detecting Alzheimer's disease
05/01/2008US20080102031 4-[(4-N,N-diethylaminocarbonyl)phenyl]-spiro[2H,1-benzopyran-2,4'-piperidine; ligands of delta opioid receptor; analgesic, anxiolitic, antidepressant, analgesic; gastrointestinal disorders, neurodegenerative diseases; side effect reduction
04/2008
04/30/2008EP1916304A2 Antigenic polypeptides associated with multiple sclerosis and uses
04/30/2008EP1916247A1 Activator of peroxisome proliferator activated receptor
04/30/2008EP1916241A1 Crystal of phenylalanine derivative, process for producing the same and use thereof
04/30/2008EP1915994A1 Cyclic amine derivative containing ppar regulator
04/30/2008EP1915992A1 Use of cyclooxygenase inhibitors and antimuscarinic agents for the treatment of incontinence
04/30/2008EP1915379A1 Olanzapine analogs and methods of use thereof
04/30/2008EP1915377A1 Pyrazolo pyrimidines useful as aurora kinase inhibitors
04/30/2008EP1915375A1 Derivatives of 5-pyridinyl-1-azabicyclo[3.2.1]octane, preparation method thereof and use of same in therapeutics
04/30/2008EP1915363A1 Oxopyridyl quinoline amides as nk3 receptor modulators
04/30/2008EP1915362A1 Amide alkyl pyridiyl quinolines as nk3 receptor modulators
04/30/2008EP1915361A1 Alkylpyridyl quinolines as nk3 receptor modulators
04/30/2008EP1915357A1 2-hydroxy-propionic acid derivatives and 3-hydroxy-benzofuran-2-one derivatives with affinity for the gaba-b-receptor
04/30/2008EP1915356A1 Therapeutic agents
04/30/2008EP1915355A1 Therapeutic agents
04/30/2008EP1915352A1 Compounds for the treatment of alzheimer's disease
04/30/2008EP1915348A1 Azinyl-3-sulfonylindazole derivatives as 5-hydroxytryptamine-6 ligands
04/30/2008EP1915345A1 Fluoro substituted 2-oxo azepan derivatives
04/30/2008EP1915339A1 Beta-secretase inhibitors for use in the treatment of alzheimer's disease
04/30/2008EP1915156A2 Method of treating parturient placental mammals in order to reduce maternal and/or utirine exhaustion
04/30/2008EP1915146A2 Novel 1-aryl-3-azabicycloý3.1.0¨hexanes: preparation and use to treat neuropsychiatric disorders
04/30/2008EP1915145A1 Use of a pkc activator, alone or combined with a pkc inhibitor to enhance long term memory
04/30/2008EP1915144A2 Method to reduce oxidative damage and improve mitochondrial efficiency
04/30/2008EP1915142A1 Composition comprising oleic acid and the use thereof
04/30/2008EP1713791B1 5-fluoro- and chloro-pyridin-2-yl-tetrazoles as ligands of the metabotropic glutamate receptor-5
04/30/2008EP1615936A4 Phosphates of secondary alcohols
04/30/2008EP1397161B1 Compounds comprising an analgesic molecule linked to a vector
04/30/2008EP1196156B1 Transnasal anticonvulsive compositions
04/30/2008EP1165613B1 Melanocortin receptor ligands