Patents for A61P 25 - Drugs for disorders of the nervous system (183,225)
05/2008
05/20/2008US7375123 1,2,4-thiadiazole derivatives as melanocortin receptor modulators
05/20/2008US7375116 NMDA (N-methyl-D-aspartate) receptors; eg 6-(4-benzylpiperidin-1-carbonyl)-1,5-dihydro-oxazolo[4,5-f]indole-2-one
05/20/2008US7375113 Nitrogenous fused-ring derivatives, medicinal compositions containing the derivatives, and use thereof as drugs
05/20/2008US7375110 Nicotinic cholinergic receptors modulators; pain, neurodegenerative diseases; neurotransmission dysfuctions; central and autonomic nervous systems disorders; 1'-(3-pyridyl)-spiro[1-azabicyclo[2.2.1]heptane-2,3'-pyrrolidine]
05/20/2008US7375106 Analgesic; Ketorolac or indomethacin nsaid with an opioid diarylmethyl piperazine such as 3-[( alpha R)- alpha -((2S,5R)-4-allyl-2,5-dimethyl-1-piperazinyl)-3-hydroxybenzyl]-N-(3-fluorophenyl)-N-methylbenzamide; dosage of the opioid can be decreased so side effects are reduced
05/20/2008US7375101 N-(7-chloro-2,3-dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)-N'-(5isoquinolinyl)-thiourea; bradykinin receptor B2 antagonists;analgesic; septic shock, pancreatitis, edema, rhinitis, asthma, colitis, arthritis, hepatorenal syndrome, cancer, bacterial and viral infections, ulcerative colitis
05/20/2008US7375099 Malonamide derivatives
05/20/2008US7375094 Produced via Streptomyces; antitumor agents; time-release agents; for opiod-resistant pain; drug screening
05/20/2008US7374937 in vitro methods of inducing proliferation of stromal cells without inducing differentiation of mesenchymal stem cells; use in gene therapy and transplantation; initial density of isolated cells is less than 50 cells per sq cm of growth surface, incubating; contacting cells with antibody to Lipocortin II
05/20/2008US7374891 Receptor for Advanced Glycated Endproducts (RAGE); detecting binding of ligand and protein in presence of peptide, lipid, carbohydrate; amyloid, high-throughput colorimetric assay
05/20/2008US7374781 Sustained release formulations containing acetaminophen and tramadol
05/20/2008US7374769 Method for treating a trigeminal neuralgia by peripheral administration of a neurotoxin
05/20/2008US7374760 Methods and compositions for nerve regeneration
05/20/2008CA2499546C Sustained released delivery of amphetamine salts
05/20/2008CA2432223C Pyrazole compounds useful as protein kinase inhibitors
05/20/2008CA2415681C Pyrrolidine derivatives
05/20/2008CA2385440C 5-hydroxysapogenin derivatives with anti-dementia activity
05/20/2008CA2385410C Sapogenin derivatives and their use in the treatment of cognitive dysfunction
05/20/2008CA2359008C Triazolo-pyridazine derivatives as ligands for gaba receptors
05/20/2008CA2322309C Quinolin-4-yl derivatives
05/20/2008CA2268257C Pharmaceutical preparation comprising eicosapentaenoic acid and/or stearidonic acid
05/20/2008CA2229202C Methods for identifying antagonist or agonist to human opioid receptor-like 1 "orl1"
05/17/2008CA2618240A1 Sustained-release formulations of topiramate
05/17/2008CA2610652A1 Extended release compositions and methods for their manufacture
05/15/2008WO2008058068A1 (r)-phenyl(heterocycle)methanol-based compounds, compositions comprising them and methods of their use
05/15/2008WO2008058037A1 Compounds and compositions as protein kinase inhibitors
05/15/2008WO2008057938A1 Nicotinic acetylcholine receptorsub-type selective amides of diazabicycloalkanes
05/15/2008WO2008057933A2 Methods of treating neuropathic pain by modulation of glycogenolysis or glycolysis pathways
05/15/2008WO2008057930A2 Methods of treating neuropathic pain with retinoic acid receptor agonists
05/15/2008WO2008057681A2 Thiophene compounds
05/15/2008WO2008056687A1 Novel spiropiperidine derivative
05/15/2008WO2008056634A1 Novel hydroxyindole derivative
05/15/2008WO2008056452A1 Utilization of rare sugar for slowing the onset or progress of mobility impairment relating to amyotrophic lateral sclerosis
05/15/2008WO2008056259A2 Oxazole derivatives as positive allosteric modulators of metabotropic glutamate receptors
05/15/2008WO2008056176A1 Pyrazolopyrimidines as phosphodiesterase inhibitors
05/15/2008WO2008056059A2 4-azasterol derivatives, methods for the synthesis thereof and use of same as drugs
05/15/2008WO2008055950A1 Novel inhibitors of glutaminyl cyclase
05/15/2008WO2008055947A1 Novel inhibitors of glutaminyl cyclase
05/15/2008WO2008055945A1 3-hydr0xy-1,5-dihydr0-pyrr0l-2-one derivatives as inhibitors of glutaminyl cyclase for the treatment of ulcer, cancer and other diseases
05/15/2008WO2008055934A1 Amorphous form of n-{2-fluoro-5-[3-(thiophene-2-carbonyl)-pyrazolo [1,5-a]pyrimidin-7-yl]-phenyl-n-methyl-acetamide
05/15/2008WO2008055933A1 1,2,3-triazole derivatives as sigma receptor inhibitors
05/15/2008WO2008055932A1 1,2,4-triazole derivatives as sigma receptor inhibitors
05/15/2008WO2008055847A1 Arylsulfonyl pyrrolidines as 5-ht6 inhibitors
05/15/2008WO2008055808A1 Indole and benzofuran 2-carboxamide derivatives
05/15/2008WO2008025790A3 Use of opioid formulations in needle-less drug delivery devices
05/15/2008WO2008024492A3 Indolinone phenylaminopropanol derivatives and process for the preparation thereof
05/15/2008WO2008015538A3 Use of diaza- and thiaza-cycloalkanediones for preventing and/or treating pain and /or migraine
05/15/2008WO2007138112A3 Compounds that interact with ion channels, in particular with ion channels from the kv family
05/15/2008WO2007130825A3 Fused heterocyclic compounds and their use as mglur5 modulators
05/15/2008WO2007052104A8 Crystalline salts of 7-[4-(4-naphthalen-1-yl-piperazin-1-yl)-but oxy]-3,4-dihydro-1h-[1,8]naphthyridin-2-one
05/15/2008WO2007045959A8 Antioxidant and fe2+chelating properties of herbal extracts
05/15/2008US20080114056 Analgesics; e.g. osteoarthritis, cancer pain, myofascial pain (muscular injury, fibromyalgia) and perioperative pain, inflammatory pain; 7-(hydroxy, ether, ester, amide, or carbamate)-3-(substituted phenyl)-chromen-4-ones; chemical synthesis
05/15/2008US20080114051 Pyrrolidine derivatives as prostaglandin modulators
05/15/2008US20080114032 Method of treating or preventing central nervous system disorders with compounds having selectivity for the alpha 3 subunit of the benzodiazepine receptor
05/15/2008US20080114023 Azaindolylalkylamine derivatives as 5-hydroxytryptamine-6 ligands
05/15/2008US20080114018 Condensed indoline derivatives and their use as 5HT, in particular 5HT2C, receptor ligands
05/15/2008US20080114014 Treating urinary and fecal incontinence in a patient being treated for a cognitive disorder consisting of one of a group of acute dementia and cognitive impairment by administration of a therapeutic amount of a quaternary ammonium anti-cholinergic muscarinic receptor antagonist
05/15/2008US20080114004 Hydrazone derivatives as kinase inhibitors
05/15/2008US20080114003 Pyrimidinylisoxazole Derivatives
05/15/2008US20080113997 Compounds, compositions, processes of making, and methods of use related to inhibiting macrophage migration inhibitory factor
05/15/2008US20080113989 For example, N-(1-Carbamoyl-1-oxo-3-phenylpropan-2-yl)-2-(E-2-(4-(1-pyrrolidinylmethyl)phenyl)ethen-1-yl)benzamide; calcium channel blockers; cardiovascular disorders; antiarthritic agents; inhibitors of enzymes, especially cysteine proteases such as calpain and cathepsins
05/15/2008US20080113988 Isoxazoline-Indole Derivatives With an Improved Antipsychotic and Anxiolytic Activity
05/15/2008US20080113985 Modulators of ATP-binding cassette transporters
05/15/2008US20080113983 (N (R)-1-Azabicyclo[2.2.2]oct-3-yl)-3-fluoro-5-phenylthiophene-2-carboxylic acid amide; antidepressant, anxiolytic, analgesic agent, cognition activator, attention disorders
05/15/2008US20080113982 Azacyclosteroid histamine-3 receptor ligands
05/15/2008US20080113978 Substituted imidazo[1,2-b]pyridazine compounds such as N-{4-chloro-5-[8-(1-ethyl-propyl)-2,6-dimethyl-imidazo[1,2-b]pyridazin-3-yl]-thiazol-2-yl}-morpholine; use as corticotropin releasing factor 1 (CRF1) receptor antagonists in the treatment of psychiatric disorders and neurological diseases
05/15/2008US20080113973 Pharmaceutical composition in unit dose form which contains a COX-2 inhibitor and a thromboxane A2 receptor antagonist; for treatment of pain or inflammation; less risk of inducing adverse cardiovascular effects than when COX-2 inhibitors are administered alone
05/15/2008US20080113969 Administering allosteric adenosine A1 receptor enhancer in conjunction with opioid analgesics or 2-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA)/kainate antagonists for alleviating postoperative pain
05/15/2008US20080113959 {Beta}-Lactamyl vasopression V1a antagonists and methods of use
05/15/2008US20080113934 Administering formulation containing pyrimido-pyrimidine selected from dipyridamole, mopidamol in combination with an agent selected fromacetylsalicylic acid (ASA), clopidogrel, ticlopidine; strongly influencing the interaction of the vessel wall with the fibrin pathway of the coagulation system
05/15/2008US20080113915 diagnosing an individual with anxiety associated with reduced expression of a SAPAP3 gene product as compared to a wild type non-human mammal of the same species that does not contain a disruption in one or both alleles of its endogenous SAPAP3 gene; drug screeing; quantitative analysis;
05/15/2008US20080113908 Use of CRF receptor agonists for the treatment or Prophylaxis of diseases, for example Neurodegenerative diseases
05/15/2008US20080113904 Treatment of Neurological Conditions Using Complement C5a Receptor Modulators
05/15/2008US20080113900 Nutraceutical; reduce serum homocysteine levels; protects cells from damage and death when exposed to oxidative stress conditions; human food supplements, multivitamin preparations, breakfast foods, infant formulas, complete diet and weight-loss formulas and bars
05/15/2008US20080113051 Methods for alleviating tattoo pain
05/15/2008US20080113032 a nonaqueous mixture of topical anesthetics, solubilizers, homopolymers, copolymers and plant extract oils, used for relieving pain on the skin or hair follicles prior to hair treatment such as braiding, electrolysis, plugging or removal
05/15/2008US20080113022 non-film-coated tablets comprising a mixture of 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole hydrochloride, microcrystalline cellulose, lubricants, colloidal silica and lactose, having stability
05/15/2008US20080113005 Composition Comprising an Extract of Gramineae Plant for the Prevention and Treatment of Ischemic Diseases and Degenerative Brain Diseases and the Use Thereof
05/15/2008US20080112946 Catalytically active recombinant memapsin and methods of use thereof
05/15/2008DE102006052755A1 New peptide derivatives and peptidomimetics are transglutaminase inhibitors useful for the treatment or prophylaxis of e.g. celiac disease, fibrosis, thrombosis, neurodegenerative disorders, Huntington's chorea and Parkinson disease
05/15/2008CA2705457A1 Novel arylbicyclo[3.1.0]hexylamines and methods and compositions for their preparation and use
05/15/2008CA2669463A1 Method for treating delirium
05/15/2008CA2668996A1 1,2,3-triazole derivatives as sigma receptor inhibitors
05/15/2008CA2668994A1 1,2,4-triazole derivatives as sigma receptor inhibitors
05/15/2008CA2668959A1 Indole and benzofuran 2-carboxamide derivatives
05/15/2008CA2668899A1 (r)-phenyl(heterocycle)methanol-based compounds, compositions comprising them and methods of their use
05/15/2008CA2668853A1 Novel triazinedione derivatives as gaba-b receptor modulators
05/15/2008CA2668682A1 Substituted 8-piperidinyl-2-pyridinyl-pyrimido [1,2-a]pyrimidin-6-one and 8-piperidinyl-2-pyrimidinyl-pyrimido[1,2-a]pyrimidin-6-one derivatives
05/15/2008CA2668679A1 Oxazole derivatives as positive allosteric modulators of metabotropic glutamate receptors
05/15/2008CA2668190A1 Compounds and compositions as protein kinase inhibitors
05/15/2008CA2667936A1 Amorphous form of n-{2-fluoro-5-[3-(thiophene-2-carbonyl)-pyrazolo [1,5-a]pyrimidin-7-yl]-phenyl}-n-methyl-acetamide
05/15/2008CA2667710A1 Arylsulfonyl pyrrolidines as 5-ht6 inhibitors
05/15/2008CA2667259A1 Dosage forms and co-administration of an opioid agonist and an opioid antagonist
05/15/2008CA2663925A1 Nicotinic acetylcholine receptor sub-type selective amides of diazabicycloalkanes
05/14/2008EP1921137A1 Antibody having inhibitory effect on amyloid fibril formation
05/14/2008EP1921133A2 System for processing lipoaspirate cells
05/14/2008EP1921080A1 Subsitituted 8-piperidinyl-2-pyridinyl-pyrimido(1,2-a)pyrimidin-6-one and 8-piperidinyl-2-pyrimidinyl-pyrimido(1,2-a)pyrimidin-6-one derivatives
05/14/2008EP1921079A1 Amorphous form of N-{2-Fluoro-5-[3-(thiophene-2-carbonyl)-pyrazolo[1,5-a] pyrimidin-7-yl]-phenyl}-N-methyl-acetamide
05/14/2008EP1921077A1 Agent for treating and/or preventing sleep disorder
05/14/2008EP1921076A1 systhesis of procyanidin B2