Patents for A61P 25 - Drugs for disorders of the nervous system (183,225)
11/1999
11/25/1999WO1999047517A8 Novel heterocyclic compounds
11/25/1999WO1999047158A3 Therapeutic chemokine receptor antagonists
11/25/1999WO1999040068A3 2-aminoquinoline derivatives having d4-agonistic activity
11/25/1999WO1999040067A3 Benzisoxazole derivatives having d4-antagonistic activity
11/25/1999CA2333203A1 Methods for modulating neuronal cell death
11/25/1999CA2333103A1 Method of locking 1.alpha.-oh of vitamin d compounds in axial orientation
11/25/1999CA2332771A1 Ionophore containing composition for modulating amyloidosis
11/25/1999CA2332711A1 Use of derivatives of aryl(or heteroaryl)azolylcarbinols in the manufacture of a medicament for the treatment of neurogenic inflammation
11/25/1999CA2332505A1 Serotonergic 5ht7 receptor compounds for treating ocular and cns disorders
11/25/1999CA2332316A1 Tetraisoquinololine derivatives as modulators of dopamine d3 receptors
11/25/1999CA2332279A1 Carboxamide compounds, compositions, and methods for inhibiting parp activity
11/25/1999CA2332253A1 Combination therapy for treatment of depression
11/25/1999CA2332239A1 Fused tricyclic compounds which inhibit parp activity
11/25/1999CA2331875A1 Imidazolidine derivatives, the production thereof, their use and pharmaceutical preparations containing the same
11/25/1999CA2328594A1 Mutant herpes simplex viruses and uses thereof
11/25/1999CA2328529A1 Immunoregulator from a human chorionic gonadotropin preparation
11/25/1999CA2327299A1 Cabergoline and pramipexole for treating cns diseases, especially parkinson's disease
11/25/1999CA2325600A1 Methods for amyloid removal using anti-amyloid antibodies
11/24/1999EP0959076A1 Heteroarylperidines and piperazines and their use as antipsychotics and analgetics
11/24/1999EP0959075A1 Heteroarylpiperidines and piperazines and their use as antipsychotics and analgetics
11/24/1999EP0959074A2 Substituted pyrazoles as CRF antagonists
11/24/1999EP0958824A2 Olanzapine (zyprexa) in combination with fluoxetine (prozac), lithium or anticonvulsant for therapy of refractory depression
11/24/1999EP0958357A2 Novel method for testing the differentiation status in pancreatic cells of a mammal
11/24/1999EP0958294A1 2-(1,2,4-triazole-1-yl)-1,3,4-thiadiazole derivatives having an effect on the c.n.s. and the heart
11/24/1999EP0958293A1 Nanomolar, non-peptide inhibitors of cathepsin d
11/24/1999EP0958282A1 2-amino-6-(2-substituted-4-phenoxy)-substituted-pyridines
11/24/1999EP0958280A1 Arylpiperidinopropanol and arylpiperazinopropanol derivatives and pharmaceuticals containing the same
11/24/1999EP0957928A1 Plant extract compositions, method of preparation, and pharmaceutical compositions containing them
11/24/1999EP0957921A1 METHOD OF PREVENTING NEURODEGENERATION AND COGNITIVE DYSFUNCTION USING 17$g(a)-DIHYDROEQUILENIN
11/24/1999EP0957914A1 Formulation of 5-ht agonists
11/24/1999EP0957913A1 N-linked sulfonamides of heterocyclic thioesters
11/24/1999EP0957907A1 Il-8 receptor antagonists
11/24/1999EP0957903A1 Pharmaceutical compositions and methods
11/24/1999EP0957901A1 Pharmaceutical preparations of glutathione and methods of administration thereof
11/24/1999EP0808165A4 Method of simultaneously enhancing analgesic potency and attenuating dependence liability caused by exogenous and endogenous opioid agonists
11/24/1999EP0666756B1 Method of producing analgesia using neurotrophins
11/24/1999CN1236317A Stable aspirin ointment preparations
11/24/1999CN1236316A Stable aspirin-containing preparations for external use
11/24/1999CN1235838A Chinese medicine for curing insomnia and neurasthenia
11/24/1999CN1235830A Medicine for curing brain dysfunction and epilepsy
11/24/1999CN1046731C Pyrrolo [2,3-d] pyrimidines and their use
11/24/1999CN1046724C Pyrazolopyridine compounds, pharmaceutical containing them, and its preparing method and use
11/24/1999CN1046723C Tetracyclic compounds, pharmaceutical containing them and its use
11/24/1999CN1046722C Heterocyclic compounds and their preparation and use
11/24/1999CN1046721C Heterocyclic compounds and their preparation and use
11/24/1999CN1046718C 6-(2-imidzolinylamino) quinoline compounds useful as alpha-2-adrenoceptor agonists
11/24/1999CN1046713C Tetrahydroisoquinoline compound, pharmaceutical composition containing them and its producing method and use
11/23/1999US5990177 Treatment of diseases mediated by the nitric oxide/cGMP/protein kinase G pathway
11/23/1999US5990170 Possesses a profile of activity which is similar to, though less potent than .delta.9-thc (tetrahydrocannabinol) with a mimicking of the psychoactive effects; analgesics; side effect reduction; cardiovascular disorders
11/23/1999US5990167 Activity-inhibitor and activity-potentiator for glutamic acid in the brain
11/23/1999US5990165 Pharmaceutical compounds
11/23/1999US5990162 Method for treatment of fibromyalgia and chronic fatigue syndrome
11/23/1999US5990160 In vitro testing of puberulic or puberulonic acid as enzyme inhibitors of inositol monophosphatase; antidepressants for depression and manic depression
11/23/1999US5990159 Pharmaceutical formulations comprising a selective serotonin reuptake inhibitors and a 5ht4 receptor antagonists; reduction of gastrointestinal side effects
11/23/1999US5990148 Side effect reductions; antiarthritic agents; nonsteroidal antiinflammatory agents
11/23/1999US5990142 Antiinflammatory agents and antiallergens having good oral adsorption and bioavailability; cardiotonic and antiischemic agents
11/23/1999US5990133 Indole derivatives as 5-HT receptor antagonist
11/23/1999US5990132 Polycyclic systems, and derivatives thereof, as neurotransmitter release enhancers useful in the treatment of cognitive disorders
11/23/1999US5990131 Heterocyclic thioesters and ketones
11/23/1999US5990129 Regulation of trka, the receptor for the neurotrophin nerve growth factor (ngf), by the administration of 2-aryl-3-aroylbenzo(b)thiophenes of given formula
11/23/1999US5990126 Quinolinic sulfide derivatives acting as NMDA receptor antagonists and process for preparation thereof
11/23/1999US5990124 Neuromuscular relaxants
11/23/1999US5990123 For treating migraine and cephalic pain, and conditions related to vasodilation; pharmacuetical compositions and methods of synthesis via reductive n-alkylation
11/23/1999US5990121 Use of 1,2-bridged 1,4-dihydropyridines as medicaments
11/23/1999US5990109 Heterocyclo-substituted imidazopyrazine protein tyrosine kinase inhibitors
11/23/1999US5990108 5H,10H-imidazo[1,2-a]indeno[1,2-e]pyrazine-4-one derivatives, preparation thereof, intermediates thereof and drugs containing the same
11/23/1999US5990105 Possess a selective affinity to 5ht-6 receptors; treating or preventing psychoses, schizophrenia, manic depressions, depressions, neurological disorders, parkinson's, amyotrophic lateral sclerosis, alzheimer's and huntington's disease
11/23/1999US5990104 Inhibiting nmda receptor activation by administering derivatives of given formula, such as 5,6,7,8,9,11,12-heptahydro-3-hydroxy-5-methyl-10-thia-5,11 -methanobenzocyclodecen-13-amine (sulphazocine)
11/23/1999US5990102 Substituted azetidin-2-ones for treatment of atherosclerosis
11/23/1999US5990080 Use of protein S-100-b in medicines containing the protein S-100b
11/23/1999US5989858 Dead-type ATP-dependent RNA helicase (DbpB) from Staphylococcus aureus
11/23/1999US5989834 Contacting nonneuronal cells transfected with vector; gene expression
11/23/1999US5989822 Diagnosis and treatment of cancer, neurodegenerative and autoimmune diseases; gene expression
11/23/1999US5989803 Method for treating a subject suffering from a condition associated with an extracellular zinc sphingomyelinase
11/23/1999US5989545 Clostridial toxin derivatives able to modify peripheral sensory afferent functions
11/23/1999CA2145618C Use of aminoglycosides to protect against excitotoxic neuron damage
11/23/1999CA2011587C Nerve growth factor secretion inducing composition
11/23/1999CA1340825C Hyaluronic acid fraction for use as a drug delivery system for medicaments
11/18/1999WO1999058968A1 Diagnosis of predisposition to epilepsy and monitoring of antiepileptic treatment
11/18/1999WO1999058642A2 Secreted proteins and polynucleotides encoding them
11/18/1999WO1999058564A1 Frameshift mutants of beta-amyloid precursor protein and ubiquitin-b and their use
11/18/1999WO1999058555A2 Water-soluble pro-drugs of 2,6-diisopropylphenol analogues
11/18/1999WO1999058545A1 Process for preparation of 4,5-epoxymorphinan-6-oxyglucuronides
11/18/1999WO1999058533A1 Phenylurea and phenylthio urea derivatives
11/18/1999WO1999058531A1 Novel substituted aryl hydroxamic acids as metalloproteinase inhibitors
11/18/1999WO1999058528A1 Substituted aryl hydroxamic acids as metalloproteinase inhibitors
11/18/1999WO1999058527A2 Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient
11/18/1999WO1999058525A1 Indole derivatives as 5-ht2a ligands and as serotonine reuptake inhibitors
11/18/1999WO1999058504A1 Novel 1,2,5-trisubstituted 1,2-dihydro-indazol-3-ones with anti-asthmatic, anti-allergic, anti-inflammatory, immuno-modulating and neuro-protective effect, method for the production and use thereof as a medicament
11/18/1999WO1999058502A1 Heterocyclic inhibitors of p38
11/18/1999WO1999058499A1 Phenylsulfonamide-phenylethylamines useful as dopamine receptors
11/18/1999WO1999058496A1 Novel substituted cyclic compounds, preparation method and pharmaceutical compositions containing them
11/18/1999WO1999058495A1 Novel substituted cyclic compounds, preparation method and pharmaceutical compositions containing them
11/18/1999WO1999058138A1 Herbal drug composition for the prevention and treatment of dementia
11/18/1999WO1999058130A1 New drug combinations of a n.a.r.i., preferably reboxetine, and pindolol
11/18/1999WO1999058116A2 Novel formulation containing paroxetine
11/18/1999WO1999058115A1 Antidepressant therapy
11/18/1999WO1999058113A2 Novel formulation containing paroxetine
11/18/1999WO1999058096A2 Analogs of 2-phthalimidinoglutaric acid and their use as inhibitors of angiogenesis
11/18/1999WO1999051216A3 3-pyridyloxyalkylamine or aryloxyalkylamine derivatives as cholinergic agonists