Patents for A61P 25 - Drugs for disorders of the nervous system (183,225)
12/1999
12/29/1999WO1999067220A1 Compounds for inhibiting beta-amyloid peptide release and/or its synthesis
12/29/1999WO1999067219A1 Compounds for inhibiting beta-amyloid peptide release and/or its synthesis
12/29/1999WO1999067199A1 2-fluoro-2-alkyl alkanoamides with anticonvulsant activity
12/29/1999WO1999066959A2 Compositions and methods for delivery of genetic material for altering neuronal growth, regeneration, and survival
12/29/1999WO1999066944A1 Methods for identifying novel multimeric agents that modulate receptors
12/29/1999WO1999066943A1 Dietary supplement for supporting cerebrovascular tone
12/29/1999WO1999066934A1 CYCLIC AMINO ACID COMPOUNDS, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS BY USE OF SUCH COMPOUNDS
12/29/1999WO1999066931A1 Use of 1-(aminoalkyl)-3-quinoxaline-2-one derivatives for the preparation of compounds having an antioxidant action
12/29/1999WO1999066920A1 The use of valproic acid analog for the treatment and prevention of migraine and affective illness
12/29/1999WO1999066918A1 Therapeutic methods employing disulfide derivatives of dithiocarbamates and compositions useful therefor
12/29/1999WO1999066914A2 Neuroprotective composition for the prevention and/or treatment of nervous and behavioural alterations due to anxiety states or depression, comprising acetyl-l-carnitine and hypericin
12/29/1999WO1999054315A3 Triazolones with a neuroprotective action
12/29/1999WO1999051626A3 Template associated npy y2-receptor agonists
12/29/1999EP0967207A1 Nitrone derivatives, process for their preparation and pharmaceutical compositions containing them
12/29/1999EP0966970A1 Antigen specific to meniere's disease and medical use thereof
12/29/1999EP0966969A1 Anti-stress drugs and functional foods having anti-stress effects
12/29/1999EP0966967A2 Combination therapy of olanzapine (zyprexa) and fluoxetine (prozac) for treatment of bipolar disorder
12/29/1999EP0966966A2 Nefazodone dosage form
12/29/1999EP0966964A1 Methods for increasing levels of acetylcholine
12/29/1999EP0966962A1 Modafinil having defined particle size
12/29/1999EP0966533A1 Activity dependent neurotrophic factor iii (adnf iii)
12/29/1999EP0966484A1 Neurotactin and uses therefor
12/29/1999EP0966479A1 Polyprolyl inhibitors of cyclophilin
12/29/1999EP0966473A1 Thiazolobenzoheterocycles, preparation and medicines containing same
12/29/1999EP0966470A1 Dioxino derivatives and their use as therapeutic agents
12/29/1999EP0966463A1 Crystalline hydrated sodium salt of (e)-4,6-dichloro-3-(2-oxo-1-phenylpyrrolidin-3-ylidene methyl)-1h-indole-2-carboxylic acid
12/29/1999EP0966448A1 Pyrazine compounds
12/29/1999EP0966442A1 Quinoline and quinazoline derivatives having corticotropin releasing factor (crf) antagonist activity
12/29/1999EP0966436A1 Aryl sulfonamides and analogues thereof and their use in the treatment of neurodegenerative diseases
12/29/1999EP0966435A1 Aminoindan derivatives
12/29/1999EP0966292A1 Mononuclear phagocytes and their use to promote axonal regeneration
12/29/1999EP0966287A1 Oxacarbazepine film-coated tablets
12/29/1999EP0966286A1 Attenuation of opioid tolerance by inhibiting inducible nitric oxide synthase pathways in the treatment of pain
12/29/1999EP0966277A1 Use of r-nsaid's for the prevention of alzheimer's disease
12/29/1999EP0938477A4 Benzothiazo and related heterocyclic group-containing cysteine and serine protease inhibitors
12/29/1999EP0785932B1 Pyrrolyl tetrahydrobenzoquinoxaline diones, their preparation and use as glutamate receptor antagonists
12/29/1999EP0677514B1 Cyclopropyl derivatives, preparation method thereof and applications
12/29/1999EP0612314B1 2-pyrazinylethylamine derivatives and their use as pharmaceuticals
12/29/1999EP0379483B1 1,2,3,4,10,14b-HEXAHYDRODIBENZO c,f]PYRAZINO- 1,2-a]AZEPINO DERIVATIVES
12/29/1999CN1239962A 1,4-diazabicyclo [2,2,2] oct-2-ylmethyl derivatives, their preparation and therapeutic application
12/29/1999CN1239952A 6-phenylpyridyl-2-amine derivatives useful as NOS inhibitors
12/29/1999CN1239951A Novel substituted tetrahydropyridin derivatives, method of preparation and pharmaceutical compositions containing them
12/29/1999CN1239950A New derivates from piperidine-keto acid, their preparation and use
12/29/1999CN1239949A Novel heterocyclically substituted benzamides and their use in fighting diseases
12/29/1999CN1239941A Aryl or heteroaryl substd. 3, 4-dihydroanthracene and benzo [1,2-g]-chrom-3-ene, benzo [1,2-g]-thiochrom-3-ene and benzo [1,2-g]-1,2-dihydroquinoline derivs.
12/29/1999CN1239892A Use of equilenin as antioxidant
12/29/1999CN1239891A Use of 17 '-dihydroequilenin as an antioxidant
12/29/1999CN1239890A 17 'alpha'-dihydroequilenin for use as medical antioxidant
12/29/1999CN1239889A Novel compounds useful as neuro-protective agents
12/29/1999CN1239887A Pharmaceutical compositions containing N-sulphonyl indolin derivatives
12/29/1999CN1239886A Benzodioxole, benzofuran, dihydrobenzofuran, and benzodioxane melatonergic agent
12/29/1999CN1047776C Pharmacologically active pyridine derivatives and process for the preparation thereof
12/29/1999CN1047775C N-piperidino 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl pyrazole-3-formyl amide, its preparation and drug composition
12/29/1999CA2342778A1 Inhibitors of .alpha.4.beta.1 mediated cell adhesion
12/29/1999CA2335992A1 Prodrugs of dipeptidyl peptidase iv inhibitors
12/29/1999CA2335978A1 Compounds of unstable dipeptidyl peptidase iv inhibitors
12/29/1999CA2335858A1 Therapeutic methods employing disulfide derivatives of dithiocarbamates and compositions useful therefor
12/29/1999CA2335711A1 4,5,6 and 7-indole and indoline derivatives, their preparation and use
12/29/1999CA2335641A1 The use of valproic acid analog for the treatment and prevention of migraine and affective illness
12/29/1999CA2335598A1 2-fluoro-2-alkyl alkanoamides with anticonvulsant activity
12/29/1999CA2335545A1 Novel form of irbesartan, methods for obtaining said form and pharmaceutical compositions containing same
12/29/1999CA2335190A1 New 2-aminocarbonyl-5(2h)-isoxazolones as ligands of a dfp-binding site for treatment of cns-diseases
12/29/1999CA2331923A1 Nucleic sequence and deduced protein sequence family with human endogenous retroviral motifs, and their uses
12/29/1999CA2330175A1 Ependymal neural stem cells and method for their isolation
12/29/1999CA2330026A1 Compositions and methods for delivery of agents for altering neuronal growth, regeneration, and survival
12/29/1999CA2325389A1 Compounds for inhibiting beta-amyloid peptide release and/or its synthesis
12/29/1999CA2325388A1 Compounds for inhibiting beta-amyloid peptide release and/or its synthesis
12/29/1999CA2324475A1 Cyclic amino acid compounds, pharmaceutical compositions comprising same, and methods for inhibiting .beta.-amyloid peptide release and/or its synthesis by use of such compounds
12/29/1999CA2324474A1 Compounds for inhibiting beta-amyloid peptide release and/or its synthesis
12/29/1999CA2319650A1 Methods for identifying novel multimeric agents that modulate receptors
12/29/1999CA2301107A1 Pyrazolo(3,4-d)pyrimidines with anticonvulsive and antiallergic/antiasthmatic action
12/28/1999US6008357 1 -azabicyclo(2.2.2)octan-3-amine, (2-diphenylmethyl)-n-((2-methoxy-5-(1-methylethyl)phenyl)methy l) is reacted with 1r-(-)-10-camphorsulfonic acid to obtain camphorsulfonic acid salt
12/28/1999US6008355 Oxidizing codeine to form codeinone, converting codeinone to oxycodone in a two step one pot reaction: reacting codeinone with hydrogen peroxide in water in presence of an acid to form 14-hydroxycodeinone then hydrogenating the intermediate
12/28/1999US6008354 Protecting hydroxy group of morphine in 3 and 6 position, demethylating n-methyl on 17 position and hydrolizing the acyl group, forming 17-benzyl-3(o)protected group, oxidizing to form intermediate, hydrogenation of intermediate
12/28/1999US6008258 d-methadone, a nonopioid analegesic
12/28/1999US6008233 (1S,2S)-1-(4-hydroxyphenyl)-2-(4-hydroxy-4-phenylipiperidin-1-yl)-1-propanolmethanesulfonate trihydrate
12/28/1999US6008232 Methods for preventing headaches
12/28/1999US6008227 Process for blocking 5-HT and dopamine uptake with biologically active tropane derivatives
12/28/1999US6008221 Method for treating Alzheimer's disease with folic acid
12/28/1999US6008219 Bicyclic amine derivatives and their use as anti-psychotic agents
12/28/1999US6008050 A polynucleotide encoding a polypeptide related to g protein coupled 7 transmembrane receptors; diagnosis/therapy of heart diseases, osteoporosis, anxiety, eating disorders, schizophrenia, ulcers, parkinson's/huntington's disease
12/28/1999US6008042 A polynucleotide; diagnosis and therapy for stroke, septic shock, acquired immune deficiency syndrome, osteoporosis, antiarthritic/antiinflammatory/antiischemic agents, genetic disorders; alzheimer's/parkinson's diseases
12/28/1999US6008017 Human cardiac/brain tolloid-like protein
12/28/1999US6008015 Glycine transporter
12/28/1999US6007986 Methods for anti-addictive narcotic analgesic activity screening
12/28/1999US6007834 Nasal melatonin composition
12/28/1999CA2118171C Galanthamine derivatives, a process for their preparation and their use as medicaments
12/28/1999CA2013087C Carbonate derivatives of eseroline, a process for their preparation and their use as medicaments
12/28/1999CA1340862C Method of producing a human protein and dna-sequence for use when carrying out the method
12/23/1999WO1999066075A2 Diagnostic method based on quantification of extramitochondrial dna
12/23/1999WO1999066072A2 Methods for treating a neurological disease by determining bche genotype
12/23/1999WO1999066051A2 Nek-related and bub1-related protein kinases
12/23/1999WO1999065939A1 INTERACTION OF p27(KIP1) WITH FKBP-12
12/23/1999WO1999065933A1 Novel cyclosporins
12/23/1999WO1999065917A1 Use of diazepins for preparing medicines for treating pathological conditions or diseases involving one of the growth hormone release inhibiting factor receptors
12/23/1999WO1999065912A1 Imidazotriazolopyrimidines used as a drug having an adenosine antagonist activity
12/23/1999WO1999065909A1 PYRROLO[2,3-d]PYRIMIDINE COMPOUNDS
12/23/1999WO1999065908A1 PYRROLO[2,3-d]PYRIMIDINE COMPOUNDS
12/23/1999WO1999065907A1 Triazolo-pyrimidines as ligands for gaba receptors
12/23/1999WO1999065906A1 Bicyclic piperidine and piperazine compounds having 5-ht6 receptor affinity