Patents for A61P 19 - Drugs for skeletal disorders (81,981)
01/2004
01/02/2004EP1373300A2 Novel use of a peptide class of compound for treating non neuropathic inflammatory pain
01/02/2004EP1373269A1 Jun kinase inhibitors
01/02/2004EP1373262A2 Azacycloalkyl substituted acetic acid derivatives for use as mmp inhibitors
01/02/2004EP1373258A1 Ether derivatives useful as inhibitors of pde4 isozymes
01/02/2004EP1373257A1 Inhibitors of c-jun n-terminal kinases (jnk) and other protein kinases
01/02/2004EP1373256A1 Ccr5 antagonists useful for treating aids
01/02/2004EP1373249A1 Imidazolidine derivatives, their preparation, and their use as antinflamatory agent
01/02/2004EP1373248A1 Benzimidazol derivatives modulate chemokine receptors
01/02/2004EP1373242A1 Dimeric isoflavones
01/02/2004EP1373233A1 Derivatives of n-(arylsulfonyl)beta-aminoacids comprising a substituted aminomethyl group, the preparation method thereof and the pharmaceutical compositions containing same
01/02/2004EP1373224A1 New spirotricyclic derivatives and their use as phosphodiesterase-7 inhibitors
01/02/2004EP1373223A1 Cyano-substituted dihydropyrimidine compounds and their use to treat diseases
01/02/2004EP1373217A1 2-mercapto-4,5-diarylimidazole derivatives and the use thereof as cyclooxygenase inhibitors
01/02/2004EP1373206A1 Aryl oxime-piperazines useful as ccr5 antagonists
01/02/2004EP1373205A1 Novel piperidine derivatives as modulators of chemokine receptors
01/02/2004EP1373204A2 Heterocyclic compounds
01/02/2004EP1373199A2 Spiro-cyclic beta-amino acid derivatives as inhibitors of matrix metalloproteinases and tnf-alpha converting enzyme (tage)
01/02/2004EP1373191A1 Acylated indanyl amines and their use as pharmaceuticals
01/02/2004EP1373185A2 Hydrophobic polyamine analogs and methods for their use
01/02/2004EP1372739A2 Stabilized therapeutic and imaging agents
01/02/2004EP1372720A1 Methods of preventing or treating inflammatory or autoimmune disorders by administering integrin alphav beta3 antagonists
01/02/2004EP1372696A2 Methods for treating rheumatic diseases using a soluble ctla4 molecule
01/02/2004EP1372690A2 93870, a human g-protein coupled receptor and uses therefor
01/02/2004EP1372669A1 Composition comprising bisphosphonates for prevention and/or treatment of metabolic diseases of bones, process for preparing such composition and use thereof
01/02/2004EP1372667A2 Compositions for delivering bisphosphonates
01/02/2004EP1372655A2 Cathepsin cysteine protease inhibitors
01/02/2004EP1372654A2 Quinoline inhibitors of hyak1 and hyak3 kinases
01/02/2004EP1372651A1 Novel amides, preparation and therapeutic use as modulators of ccr-receptor activity
01/02/2004EP1372648A2 Tie2 receptor kinase inhibitors for treating angiogenic diseases
01/02/2004EP1372647A2 Use of substituted imidazo 1,2-a]-pyridine compounds as medicaments
01/02/2004EP1372634A2 Fumaric acid amides
01/02/2004EP1372627A1 Use of breakers of advanced glycation endproducts for treating deleterious effects of aging and debilitating diseases
01/02/2004EP1372412A2 Composition improving age-related physiological deficits and increasing longevity
01/02/2004EP1036062B1 Hydroxamic acid derivatives as matrix metalloprotease (mmp) inhibitors
01/01/2004US20040002537 Multiple sclerosis; central nervous system disorders; side effect reduction
01/01/2004US20040002534 Stem cell factor; signal transduction passageways; anticancer agents
01/01/2004US20040002525 Obesity; osteoporosis
01/01/2004US20040002524 Cardiovascular disorders; osteoporosis; central nervous system disorders
01/01/2004US20040002519 Mixture of hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, insulin elimination promoter and insulin sensitizer with carrier
01/01/2004US20040002511 Novel pyrazolo[1,5-a]pyridine derivatives and their use as neurotransmitter modulators
01/01/2004US20040002508 Antitumor agents; anticancer agents; sexual disorders; cardiovascular disorders
01/01/2004US20040002507 Rho-kinase inhibitors
01/01/2004US20040002501 Modulate signal transduction; antitumor, anticancer agents, vision defects, antidiabetic agents, antiinflammatory agents
01/01/2004US20040002496 Compositions useful as inhibitors of protein kinases
01/01/2004US20040002493 Benzoic acid derivatives and pharmaceutical agents comprising the same as active ingredient
01/01/2004US20040002482 Androgen pharmaceutical composition and method for treating depression
01/01/2004US20040002481 Novel 4-dedimethylaminotetracycline derivatives
01/01/2004US20040002134 Novel nucleic acid sequences encoding human KIAA0768 protein-like and human protein PRO228-like polypeptides
01/01/2004US20040002066 36 human secreted proteins
01/01/2004US20040001824 Cell proliferation inhibitors
01/01/2004US20040001818 Prevention endothelial cell migration; antiproliferative agent; diaphorase inhibitor
12/2003
12/31/2003WO2004001023A2 Method and device for multiplying and differentiating cells in the presence of growth factors and of a biological matrix or of a supporting structure
12/31/2003WO2004001004A2 Membrane associated tumor endothelium markers
12/31/2003WO2004000887A1 Compounds that bind to the interferon-gamma, preparation method thereof and medicaments containing same
12/31/2003WO2004000846A1 Arylamine substututed bicyclic heteroaromatic compounds as p38 kinase inhibitors
12/31/2003WO2004000843A1 NOVEL PURINE- OR PYRROLOL[2,3-d]PYRIMIDINE-2-CARBONITILES FOR TREATING DISEASES ASSOCIATED WITH CYSTEINE PROTEASE ACTIVITY
12/31/2003WO2004000839A1 Thiazole derivatives as phosphodiesterase iv inhibitors
12/31/2003WO2004000833A1 Processes for preparing substituted pyrimidines and pyrimidine derivatives as inhibitors of protein kinase
12/31/2003WO2004000819A1 New use of pyrimidine - or triazine- 2-carbonitiles for treating diseases associated with cysteine protease activity and novel pyrimidine-2-carbonitile derivatives
12/31/2003WO2004000817A2 Benzimidazole compounds and their use as estrogen agonists/antagonists
12/31/2003WO2004000816A1 Androgen receptor agonist
12/31/2003WO2004000807A1 Cannabinoid receptor agonists
12/31/2003WO2004000781A2 Nitrooxyderivatives of cyclooxygenase-2 inhibitors
12/31/2003WO2004000369A2 Method of magnetically manipulating a cell with magnetisable particles
12/31/2003WO2004000368A1 Pharmaceutical use of nitric oxide, heme oxygenase-1 and products of heme degradation
12/31/2003WO2004000365A1 Drug transport and delivery system
12/31/2003WO2004000364A1 Preparation containing polydimethylsiloxane for nails, cartilage, bone joint, muscle and tendon disorders
12/31/2003WO2004000345A1 Preventives/remedies for bone and joint diseases
12/31/2003WO2004000342A1 Use of mixtures of active substances for the production of a medicament against rheumatic arthritis
12/31/2003WO2004000333A1 Novel complexes of fatty acid esters of polyhydroxyalkanes and pyridine carboxy derivatives
12/31/2003WO2004000322A1 Thiazine and oxazine derivatives as mmp-13 inhibitors for treating arthritis
12/31/2003WO2004000321A1 Thiazine and oxazine derivatives as mmp-13 inhibitors for treating arthritis
12/31/2003WO2004000312A2 Medicament for the treatment of diseases requiring inhibition or a reduction in the activity of ph value-regulating bicarbonate transporter proteins
12/31/2003WO2004000300A1 Cyclooxygenase-2 inhibitors
12/31/2003WO2004000245A1 Promoter for uptake of basic amino acid into cell and cosmetic or drug composition
12/31/2003WO2004000205A2 Novel tetracyclic arylcarbonyl indoles having serotonin receptor affinity useful as therapeutic agents, process for their preparation and pharmaceutical compositions containing them
12/31/2003WO2003077832A3 Dexanabinol and dexanabinol analogs regulate inflammation related genes
12/31/2003WO2003072704A3 RNA INTERFERENCE MEDIATED INHIBITION OF PLATELET DERIVED GROWTH FACTOR (PDGF) AND PLATELET DERIVED GROWTH FACTOR RECEPTOR (PDGFR) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
12/31/2003WO2003068811A3 Cytotoxic t-cell epitopes from chlamydia
12/31/2003WO2003063758A3 Bicyclic cb2 cannabinoid receptor ligands
12/31/2003WO2003059269A3 Acridone inhibitors of impdh enzyme
12/31/2003WO2003055916A3 Adiponectin fragments and conjugates
12/31/2003WO2003055912A3 Secreted proteins
12/31/2003WO2003020759A9 A caspase- 8 binding protein, its preparation and use
12/31/2003WO2003010286A9 Nucleic acids, polypeptides, and methods for modulating apoptosis
12/31/2003WO2002070562A3 Nuclear hormone receptor ligand binding domain
12/31/2003WO2002060378A3 Substituted aryl compounds as cyclooxygenase-2 selective inhibitors, compositions and methods of use
12/31/2003WO2002055075A3 Compounds and methods for regulating cell differentiation
12/31/2003WO2002047708A3 Selective cox-2 inhibition from edible plant extracts
12/31/2003WO2002047706A3 Selective cox-2 inhibition from plant extracts
12/31/2003WO2002040671A3 Immunoglobulin superfamily proteins
12/31/2003WO2001006984A3 Small molecules useful in the treatment of inflammatory disease
12/31/2003CN1464881A New dipeptidyl peptidase iv inhibitors and their uses as anti-cancer agents
12/31/2003CN1464791A Compositions for protein delivery via the pulmonary route
12/31/2003CN1463724A A pharmaceutical composition for treating lumbago and pain on legs
12/31/2003CN1463723A A medicine for treating bone fracture and dislocation and method for preparing same
12/31/2003CN1463702A Analgetic pharmaceutical composition
12/31/2003CN1132819C 作为TNF-α抑制剂的环状肼衍生物 Examples of the cyclic hydrazine derivative TNF-α inhibitors
12/31/2003CN1132814C 含有磺酰胺的吲哚化合物 Sulfonamide-containing indole compound
12/31/2003CN1132616C Traditional Chinese medicine for treating arthralgia-syndrome