Patents for A61P 19 - Drugs for skeletal disorders (81,981)
02/2004
02/03/2004US6686371 Having an 11h-benzo(b)fluorene, an 11h-indeno-(1,2-b) quinoline, a benz(a)anthracene or analogous skeleton and an affinity for the estrogen receptor; contraceptives; menopausal complaints, osteoporosis; antitumor agents
02/03/2004US6686355 Biphenyl sulfonamides useful as matrix metalloproteinase inhibitors
02/03/2004US6686353 Diarylalkyl cyclic diamine derivatives as chemokine receptor antagonists
02/03/2004US6686351 Compounds and methods for modulation of estrogen receptors
02/03/2004US6686348 Metalloprotease inhibitors
02/03/2004US6686347 Phthalazine derivatives for treating inflammatory diseases
02/03/2004US6686335 Hydroxamate-containing cysteine and serine protease inhibitors
02/03/2004US6686153 PRV-1 gene and the use thereof
02/03/2004US6686148 Methods for targeting RNA molecules
01/2004
01/31/2004CA2436469A1 Composition for heart disease, method to prepare same and uses thereof
01/29/2004WO2004009816A1 Methods of treating conditions associated with an edg-1 receptor
01/29/2004WO2004009784A2 Novel inhibitors of kinases
01/29/2004WO2004009603A1 Dihydro-dibenzo[b,e]oxepine based selective estrogen receptor modulators, compositions and methods
01/29/2004WO2004009601A1 Azaindole kinase inhibitors
01/29/2004WO2004009592A1 Bicyclic unsaturated tertiary amine compound
01/29/2004WO2004009588A1 Bicyclic piperidine derivatives as antagonists of the ccr1 chemokine receptor
01/29/2004WO2004009582A1 Substituted thiophene carboxamide compounds for the treatment of inflammation
01/29/2004WO2004009579A1 Novel compounds
01/29/2004WO2004009578A2 Pentacyclic oxepines and derivatives thereof, process for their preparation and pharmaceutical compositions containing them
01/29/2004WO2004009563A1 5-aryltetrazole compounds, compositions thereof, and uses therefor
01/29/2004WO2004009562A1 Substituted triazine kinase inhibitors
01/29/2004WO2004009560A1 Novel bio-active molecules
01/29/2004WO2004009556A1 4-(substituted aryl)-5-hydroxyisoquinolinone derivative
01/29/2004WO2004009547A1 Indoline derivatives substituted in position 6, production and use thereof as medicaments
01/29/2004WO2004009546A1 Indoline derivatives substituted in position 6, production and use thereof as medicaments
01/29/2004WO2004009537A1 NOVEL α-KETOAMIDE DERIVATIVE AND USE THEREOF
01/29/2004WO2004009528A1 2,4-dihydroxybenzoic acid derivatives
01/29/2004WO2004009120A1 Hybrid of itraconazole, cyclosporine or carvedilol with a layered silicate and a process for preparing the same
01/29/2004WO2004009113A1 Use of convertase inhibitors in the treatment of fibrosis and scarring
01/29/2004WO2004009098A1 Antisense compounds, methods and compositions for treating mmp-12 related inflammatory disorders
01/29/2004WO2004009081A1 Use of neomycin in the preparation of medicaments that are used in the treatment of diseases caused by hyperactivation of kinase proteins activated by mitogens (mapk) or by transcription factors
01/29/2004WO2004009064A1 Use of neurotoxic substances for the production of a means for the treatment of joint pain and method for application of said means
01/29/2004WO2004009061A2 Bioavailability/bioefficacy enhaning activity of cuminum cyminum and extracts and fractions thereof
01/29/2004WO2004009030A2 Angiogenesis inhibition by cephalotaxine alkaloids, derivatives, compositions and uses thereof
01/29/2004WO2004008887A1 Fruit and/or vegetable derived composition
01/29/2004WO2003088748A8 Use of heme oxygenase-1 and products of heme degradation
01/29/2004WO2003059932A3 Methods of inducing or enhancing connective tissue repair
01/29/2004WO2003053923A3 Pyrrolidine derivatives as prostaglandin modulators
01/29/2004WO2003053366A3 Pyrimidine a2b selective antagonist compounds, their synthesis and use
01/29/2004WO2003040080A3 Lipoxin a4 analogs
01/29/2004WO2003020324A3 Methods for sterilizing preparations of digestive enzymes
01/29/2004WO2003002137A3 Trp1, mct, or ftz-f1 homologous proteins involved in the regulation of energy homeostasis
01/29/2004WO2003000194A3 Thienopyridine and thienopyrimidine anticancer agents
01/29/2004WO2003000180A3 Dipeptidyl peptidase inhibitors for the treatment of diabetes
01/29/2004WO2002072794A3 Immunoglobulin superfamily proteins
01/29/2004WO2002070737A3 Compositions and methods relating to osteoarthritis
01/29/2004WO2002038106A3 Calcilytic compounds
01/29/2004US20040019361 Method, instruments, and kit for autologous transplantation
01/29/2004US20040019232 Analogs of phosphonate and bisphosphonate compounds based on bone resorption suppressors (alendronic acid), viricides (cidofovir) and antineoplastic agents (bemcitabine); nontoxic; bioavailability; side effects reduction
01/29/2004US20040019210 Kinase inhibitors
01/29/2004US20040019208 5-Aryltetrazole Compounds, compositions thereof, and uses therefor
01/29/2004US20040019191 Derivatives of 2-3-O- isopropylidene- alpha -L-xylo-2-hexulofuranosonic acid, useful for treating inflammatory and autoimmune diseases
01/29/2004US20040019184 Remedies for ischemic disease
01/29/2004US20040019114 4-Fluoro-N-indan-2-yl benzamide and its use as a pharmaceutical
01/29/2004US20040019113 Phosphate transport inhibitors
01/29/2004US20040019111 A new use of existing pharmaceutical, a nonsteroidal antiinflammatory agents
01/29/2004US20040019106 Cyano and carboxy derivatives of substituted styrenes; inhibitors of tumor necrosis factor alpha, nuclear factor kappa B, and phosphodiesterase
01/29/2004US20040019063 Nitrogen compounds such as 4-(7-Hydroxy-1,3-dioxo-tetrahydro-pyrrolo(1,2-c)imidazol-2-yl)-5,6,7,8-tetrahydronaphthalene-1-carbonitrile, used for prophylaxis of muscular disorders; aging
01/29/2004US20040019059 Drugs such as N-(4-benzoylphenyl)-4,5-dihydro-3-(3-pyridinyl)-5-isoxazolecarboxamide, used as antiinflammatory or antiarthritic agents
01/29/2004US20040019055 Combination of an allosteric alkyne inhibitor of matrix metalloproteinase-13 with a selective inhibitor of cyclooxygenase-2 that is not celecoxib or valdecoxib
01/29/2004US20040019054 Combination of an allosteric carboxylic inhibitor of matrix metalloproteinase-13 with a selective inhibitor of cyclooxygenase-2 that is not celecoxib or valdecoxib
01/29/2004US20040019046 Phenylacetamido-pyrazole derivatives and their use as antitumor agents
01/29/2004US20040019045 Pyrazole compounds as anti-inflammatory and analgesic agents
01/29/2004US20040019040 1,2,3,4,7,8-Hexahydro-6H-[1,4]diazepino[6,7,1-ij]quinoline derivatives as antipsychotic and antiobesity agents
01/29/2004US20040019038 Compounds useful as anti-inflammatory agents
01/29/2004US20040019037 E.g.,((5-(2,4-Diaminopyrimidin-6-yl)pentanoyl)-(N-methyl)amino )-3-(6-meth-oxypyridin-3-yl)-propanoic acid, inhibition of bone resorption, restenosis, angiogenesis inhibitors, antiarthritic, -tumor, -carcinogenic agents; antidiabetic
01/29/2004US20040019035 3-(5,6,7,8-Tetrahydro-(1,8)naphthyridin-2-yl)-ethoxy)-11H-di-b enzo(1,4)oxazepin-10-yl)-acetic acid; inhibiting bone resorption; vascular restenosis; osteoporosis; angiogenesis inhibitors; diabetic retinopathy; anticarcinogenic agents
01/29/2004US20040019020 Phosphinyl phosphonate compounds treat hyperphosphatemia, chronic renal failure, disorders of phosphate metabolism, hyperparathyroidism, uremic bone disease, soft tissue calcification or osteoporosis
01/29/2004US20040019015 Administering an effective amount of a protein tyrosine kinase inhibitor (containing first and second module) to the patient to protect against or to treat hearing loss
01/29/2004US20040018995 Antiinflammatory agents; autoimmune diseases; rheumatic diseases; antidiabetic agents
01/29/2004US20040018981 Glucagon-like peptide-1 (glp-1) receptor agonist
01/29/2004US20040018972 Autoimmune diseases; antiallergens; rheumatic diseases; antiinflammatory agents
01/29/2004US20040018595 Production of recombinant bmp-2
01/29/2004US20040018558 Method for identifying modulators of G protein coupled receptor signaling
01/29/2004US20040018508 Surrogate antibodies and methods of preparation and use thereof
01/29/2004US20040018257 In particular of avocado, soya bean and/or lupin oils, for preparation of a medicament intended to stimulate expression of TGF-62 or expression of the plasminogen activator inhibitor PAI-1
01/29/2004US20040018192 Integrin expression inhibitors
01/29/2004US20040018187 Attenuation of fibroblast proliferation
01/29/2004US20040018179 Bioadhesive directed somatic cell therapy
01/29/2004DE10229778A1 Neue Verwendung von Imidazotriazinonen New use of imidazotriazinones
01/29/2004CA2800126A1 Treatment of tnf.alpha. related disorders
01/29/2004CA2493774A1 2,4-dihydroxybenzoic acid derivatives
01/29/2004CA2493721A1 Indoline derivatives substituted in position 6, production and use thereof as medicaments
01/29/2004CA2493544A1 Angiogenesis inhibition by cephalotaxine alkaloids, derivatives, compositions and uses thereof
01/29/2004CA2493234A1 4-(substituted aryl)-5-hydroxyisoquinolinone derivative
01/29/2004CA2493232A1 Antisense compounds, methods and compositions for treating mmp-12 related inflammatory disorders
01/29/2004CA2492922A1 Substituted thiophene carboxamide compounds for the treatment of inflammation
01/29/2004CA2492847A1 5-aryltetrazole compounds, compositions thereof, and uses therefor
01/29/2004CA2492665A1 Azaindole kinase inhibitors
01/29/2004CA2492331A1 Use of convertase inhibitors in the treatment of fibrosis and scarring
01/29/2004CA2492110A1 Bicyclic piperidine derivatives as antagonists of the ccr1 chemokine receptor
01/29/2004CA2466288A1 Methods of treating conditions associated with an edg-1 receptor
01/28/2004EP1383927A2 New polynucleotides and polypeptides of the erythropoietin gene
01/28/2004EP1383919A1 Methods and compositions for using mhc class ii invariant chain polypeptide as a receptor for macrophage migration inhibitory factor
01/28/2004EP1383895A2 Polynucleotides and polypeptides of the ifnalpha-5 gene
01/28/2004EP1383892A2 Human extracellular matrix and cell adhesion polypeptides
01/28/2004EP1383883A2 Asthma-associated snps around microsatellite marker d2s308 and identification of human prolyl-oligopeptidase-dpp10
01/28/2004EP1383869A1 Progenitor cell populations, expansion thereof, and growth of non-hematopoietic cell types and tissues therefrom
01/28/2004EP1383798A2 Transporters and ion channels
01/28/2004EP1383789A2 Proteins associated with cell growth, differentiation, and death