Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
02/2012
02/22/2012EP1095183B1 Methods for the diagnosis and treatment of lung cancer
02/22/2012CN102358901A Antitumor application of has-miR-520e
02/22/2012CN101805749B 基于vsig4的模拟病毒及其制备方法和应用 Simulation-based vsig4 virus and its preparation method and application
02/22/2012CN101747451B 一种靶向粘附壳聚糖材料及其应用 Which targets the adhesion of chitosan materials and their applications
02/22/2012CN101683354B 一种肝损伤相关的药物靶点及其应用 One kind of liver injury associated with drug targets and its application
02/22/2012CN101648023B Dna与纳米层状羟基磷灰石复合物及其制备方法和应用 Dna and nano-layered hydroxyapatite compound and preparation method and application
02/22/2012CN101362802B Dna依赖蛋白激酶催化亚基单链抗体及其编码基因与应用 Dna-dependent protein kinase catalytic subunit of single-chain antibody and its coding gene and application
02/21/2012US8119791 si-RNA-mediated gene silencing technology to inhibit tyrosinase and reduce pigmentation
02/21/2012US8119789 Method for the production of a cell and/or tissue and/or disease phase specific medicament
02/21/2012US8119766 Increasing functional glycosylation of alpha-dystroglycan in the treatment of muscle degeneration
02/21/2012US8119611 Treatment of neurodegenerative disease through intracranial delivery of SIRNA
02/21/2012US8119610 Methods of making RNAi libraries using E. coli RNAse III for inhibition of mammalian gene expression
02/21/2012US8119609 Apoptosis and increased production of ceramides and DAG are normalized in the presence of antioxidants
02/21/2012US8119608 Specific inhibition of expression of target gene in mammals using short double stranded RNA; dsRNA less than 49 nucleotides in length, has nucleotide sequence complementary to part of target gene; treating cancer, Alzheimer's disease
02/21/2012US8119590 Apolipoprotein A-I (ApoA-I), preferably a variant form such as Apolipoprotein A-I Milano (ApoA-IM), alone or more preferably in combination with a lipid carrier such as phospholipids or other drug, can be administered locally
02/21/2012US8119405 Methods of inducing regulated pancreatic hormone production in non-pancreatic islet tissues
02/21/2012US8119401 IL-10 gene transfer to peripheral mononuclear cells
02/21/2012US8119400 Methods of inhibiting smooth muscle cell migration and proliferation
02/21/2012US8119396 Recombinant adenoviral vectors and applications thereof
02/21/2012US8119395 Vaccines, immunotherapeutics and methods for using the same
02/21/2012US8119119 Retroviral vector for improving exogenous gene transfer and expression in cells
02/21/2012US8119118 Helper virus-free herpesvirus amplicon particles and uses thereof
02/21/2012US8119117 Adenoviral expression vector comprising a CD40L fusion protein adapted to elicit cellular immunity
02/21/2012CA2568995C Construction of oncolytic adenovirus recombinant specifically expressing immune modulatory factor gm-csf in tumor cells and uses thereof
02/21/2012CA2407680C Dendritic cell co-stimulator molecules
02/21/2012CA2398940C Methods and compositions using stearoyl-coa desaturase to identify triglyceride reducing therapeutic agents
02/21/2012CA2373300C Compositions and methods for generating an immune response utilizing alphavirus-based vector systems
02/21/2012CA2349760C Bovine cells expressing adeno virus essential functions for propagation of recombinant adenoviral vectors
02/21/2012CA2322055C Novel mechanically sensitive mammal potassium channel family activated by polyunsaturated fatty acids and their use particularly for screening medicines
02/21/2012CA2302866C Genetically modified tumor-targeted bacteria with reduced virulence
02/21/2012CA2297303C Novel peptides and polypeptides useful for regenerating the nervous system
02/21/2012CA2296841C Tropoelastin derivatives
02/21/2012CA2269085C Rainbow trout il1.beta.; encoding nucleic acid; materials and methods
02/21/2012CA2264592C Bioconjugates and delivery of bioactive agents
02/21/2012CA2263835C Stimulus-inducible i (kappa)b kinase [ikk] signalsome
02/21/2012CA2158936C Compositions and methods for utilizing conditionally lethal genes
02/16/2012WO2012021891A2 Compositions, kits and methods for treatment of complement-related disorders
02/16/2012WO2012021735A2 Pharmaceutical products from gungal strains
02/16/2012WO2012021383A2 RNA INTERFERENCE MEDIATED INHIBITION OF MITOGEN-ACTIVATED PROTEIN KINASE 1 (MAPK1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
02/16/2012WO2012021165A2 Methods and compositions for treating disorders associated with hyperactive immune system
02/16/2012WO2012020836A1 Therapeutic agent for hepatitis c containing rrm2 antagonist as active ingredient
02/16/2012WO2012020795A1 Nucleic acid/polysaccharide complex
02/16/2012WO2012020001A1 Methods and pharmaceutical compositions for the treatment of an ocular disease in a subject
02/16/2012WO2012007632A9 Use of edg2 inhibitors for treating rheumatoid arthritis
02/16/2012WO2010107740A8 Treatment of delta-like 1 homolog (dlk1) related diseases by inhibition of natural antisense transcript to dlk1
02/16/2012US20120042399 Immunogenic peptides
02/16/2012US20120041176 Ucp4
02/16/2012US20120041050 Antisense oligonucleotides for inducing exon skipping and methods of use thereof
02/16/2012US20120040909 Identification of novel antagonist toxins of t-type calcium channel for analgesic purposes
02/16/2012US20120040829 Bacterial ghosts as carrier and targeting vehicles
02/16/2012US20120039986 Compositions and methods for sirna inhibition of angiopoietin 1 and 2 and their receptor tie2
02/16/2012US20120039938 Composition comprising the polyprotein ns3/ns4 and the polypeptide ns5b of hcv, expression vectors including the corresponding nucleic sequences and their therapeutic use
02/16/2012US20120039931 Dna composition encoding an immunogenic vegf receptor peptide and methods of use thereof
02/16/2012US20120039914 Methods and compositions for using mhc class ii invariant chain polypeptides as a receptor for macrophage migration inhibitory factor
02/16/2012US20120039909 Epigenetic mechanisms re-establish access to long-term memory after neuronal loss
02/16/2012US20120039905 The Role of p110 delta Signaling in Morbidity and Lung Pathology Induced by Influenza Virus Infection
02/16/2012US20120039858 Methods and compositions for inhibiting propagation of viruses using recombinant tetherin constructs
02/16/2012US20120039798 Methods of modifying p53 acetylation and treating cancer using avra
02/16/2012CA2807628A1 Methods and pharmaceutical compositions for the treatment of an ocular disease in a subject
02/15/2012EP2418281A2 Methods and compositions for delivering polynucleotides
02/15/2012EP2417985A1 Mitochondrial function-improving agent
02/15/2012EP2417259A1 Neuron generation, regeneration and protection
02/15/2012EP2416762A2 Controlled release devices and methods for delivery of nucleic acids
02/15/2012EP1951891B1 Cancer antigen mage-a9 and uses thereof
02/15/2012EP1532161B1 Vectors for expression of hml-2 polypeptides
02/15/2012CN102355911A Use of vgii3 activity modulator for the modulation of adipogenesis
02/15/2012CN102355910A Composition for improving inflammatory disease using abh antigens
02/15/2012CN102352368A ING4 and OSM double-gene co-expression vector and application thereof
02/15/2012CN102352358A Seventy-four rat source miRNA (ribonucleic acid) as well as corresponding miRNA precursor and antisense oligonucleotide thereof
02/15/2012CN102352356A Bcl11a siRNA-2292 restraining expression of BCL11A and proliferation of tumorous B cells and application thereof
02/15/2012CN102352355A Compositions and methods for short interfering nucleic acid inhibition of NAv1.8
02/15/2012CN102351932A Structure, preparation method and purpose of anti-influenza virus oligonucleotide
02/15/2012CN102350001A Preparation method of heterologous bluetongue virus double-strand RNA (ribonucleic acid) endogenous interferon inducer
02/15/2012CN102350000A Application of heterogeneous bluetongue virus dsRNA (double-strand ribonucleic acid) in preparation of endogenic interferon inducer
02/15/2012CN102349997A Diagnosis and prevention of cancer cell invasion
02/15/2012CN101721711B 邻菲咯啉钌环糊精-金刚烷芘-单壁碳纳米管三元超分子体系的制备方法及应用 Phenanthroline ruthenium cyclodextrin - adamantane pyrene - single-walled carbon nanotube preparation and application of ternary supramolecular system
02/15/2012CN101475503B 一种新型阳离子类脂及其制备方法和应用 A novel cationic lipid and its preparation method and application
02/14/2012US8114981 Method and medicament for inhibiting the expression of a given gene
02/14/2012US8114971 Nucleotide sequences coding gramnegative bacterial lipoprotein for use in prevention and treatment of microorganismal infection; genetic vaccine
02/14/2012US8114965 Compositions of PSMA antibodies
02/14/2012US8114852 N-linked glycosylation alteration in E1 glycoprotein of classical swine fever virus and novel classical swine fever virus vaccine
02/14/2012US8114851 Double stranded RNA packaged in liposome for use therapeutic tool in treatment of cell proliferative and viral disorders; Antisense oligonucleotide for use in prevention and treatment of viral and tumor disorders; gene expression inhibition; RNA interference
02/14/2012US8114849 Retinal dystrophy-associated protein and uses thereof
02/14/2012US8114838 Methods for protecting dopaminergic neurons from stress and promoting proliferation and differentiation of oligodendrocyte progenitors by NRG-2
02/14/2012US8114637 Packaging cells for recombinant adenovirus
02/14/2012US8114603 collecting a blood sample from the subject; andmeasuring the levels of Triggering Receptor Expressed on Myeloid cells (TREM-1) splice variant protein in sample, a decrease in the levels of TREM-1 splice variant indicates an inflammatory response
02/14/2012US8114601 Highly conserved genes and their use to generate probes and primers for detection of microorganisms
02/14/2012US8114416 Modified oncolytic viruses
02/14/2012US8114404 Method and composition for altering a B cell mediated pathology
02/14/2012US8114401 Chlamydia trachomatis antigens
02/14/2012CA2402160C Heparinase iii and uses thereof
02/14/2012CA2343135C Adenovirus vectors containing cell status-specific response elements and methods of use thereof
02/09/2012WO2012019188A2 Methods and compositions for the inhibition of fructokinase
02/09/2012WO2012019184A2 Compositions and methods for detecting, diagnosing, and treating cancer
02/09/2012WO2012019154A2 Methods and compositions for malic enzyme 2 (me2) as a target for cancer therapy
02/09/2012WO2012019121A2 Multiplexed supramolecular assemblies for non-viral delivery of genetic material
02/09/2012WO2012019060A1 Predicting and treating diabetic complications
02/09/2012WO2012018881A2 Methods and compositions for the regulation of rna
02/09/2012WO2012018877A2 Treating breast cancer with anti-il-19 antibody
02/09/2012WO2012018866A2 Methods and compositions for the diagnosis and treatment of breast cancer
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