Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
06/1996
06/05/1996EP0714308A1 Method, compositions and devices for administration of naked polynucleotides which encode biologically active peptides
06/05/1996EP0714290A1 Compositions and methods for the detection and treatment of protein trafficking disorders and increasing secretory protein production
06/05/1996CN1124040A Adenoviral vectors of animal origin and use thereof in gene therapy
06/04/1996US5523215 Culturing host cell expressing desired protein in medium containing copper ions, disrupting, incubating insoluble fraction with chaotropic agent to dissolve contaminants, separating, treating insoluble fraction with reducing agent
05/1996
05/30/1996WO1996016183A1 Suicide genes and combinations of pyrimidine nucleoside and nucleobase analogues with suicide genes for gene therapy
05/30/1996WO1996016179A1 Enzyme gene therapy catalysing prodrug extracellular conversion
05/30/1996WO1996016175A2 Lgmd gene coding for a calcium dependent protease
05/30/1996WO1996016173A2 Modified proteinase inhibitors
05/30/1996WO1996016169A1 Peptides capable of binding to the gap protein sh3 domain, nucleotide sequences coding therefor, and preparation and use thereof
05/30/1996WO1996016163A2 Embryonal cardiac muscle cells, their preparation and their use
05/30/1996WO1996016161A1 Cell-cultivation method and device for carrying out this method
05/30/1996WO1996016087A1 G-protein coupled receptor
05/30/1996WO1996015813A1 Cell compositions for use in transplantation and ex vivo gene therapy
05/30/1996WO1996015811A1 Internalisation of dna, using conjugates of poly-l-lysine and an integrin receptor ligand
05/30/1996WO1996015807A1 Sperm as vaccine vectors
05/30/1996WO1996015806A1 Human choline acetyltransferase
05/30/1996WO1996015799A1 Methods for the prevention or treatment of vascular hemorrhaging and alzheimer's disease
05/30/1996WO1996015780A1 Compositions and methods for preventing and treating allograft rejection
05/30/1996WO1996015778A1 Polynucleotide compositions
05/30/1996WO1996015777A1 Lipid vesicles containing adeno-associated virus rep protein for transgene integration and gene therapy
05/30/1996WO1996012807A3 Hepatitis e virus antigens and uses therefor
05/30/1996DE19541284A1 Verfahren zur Immunmodulation Methods for immunomodulation
05/30/1996CA2205593A1 Enzyme gene therapy catalysing prodrug extracellular conversion
05/30/1996CA2205486A1 Polynucleotide compositions
05/30/1996CA2205356A1 Modified proteinase inhibitors
05/30/1996CA2204438A1 Peptides capable of binding to the gap protein sh3 domain, nucleotide sequences coding therefor, and preparation and use thereof
05/29/1996EP0679089A4 Methods for promoting cartilage matrix formation.
05/29/1996EP0670737A4 In vivo peptide therapy.
05/29/1996CN1123326A Modified gene of human tumor necrotizing factor and its production process
05/28/1996US5521955 Method for quantitatively determining bone mineral mass by CT system
05/28/1996US5521302 Nucleophilic reaction of phosphate groups
05/28/1996US5521076 Modified hepatocytes and uses therefor
05/23/1996WO1996015245A1 A process of inhibiting non-neoplastic pathological cell proliferation
05/23/1996WO1996015241A2 A polynucleotide tuberculosis vaccine
05/23/1996WO1996015240A2 Ribozyme analogs
05/23/1996WO1996015238A1 Targeted t lymphocytes
05/23/1996WO1996015226A1 Regulation of neural stem cell proliferation
05/23/1996WO1996015224A1 In vitro induction of dopaminergic cells
05/23/1996WO1996015222A1 HUMAN MutT2
05/23/1996WO1996015144A2 Chromosome 21 gene marker, compositions and methods using same
05/23/1996WO1996015143A1 SYNTHESIS OF PEPTIDE NUCLEIC ACIDS (PNAs) AND ANALOGUES VIA SUBMONOMER APPROACH
05/23/1996WO1996014877A1 Novel tumor suppressor gene, hic-1
05/23/1996WO1996014876A1 Yeast-based delivery vehicles
05/23/1996WO1996014875A1 Novel nucleic acid molecules comprising the prostate specific antigen (psa) promoter and uses thereof
05/23/1996WO1996014874A1 Method for gene therapy involving suppression of an immune response
05/23/1996WO1996014863A1 Suppression of proteolytic activity by dysfunctional protease formation
05/23/1996WO1996014853A1 Intrathymic stem cell implantation
05/23/1996WO1996014837A1 Gene therapy for hypercholesterolemia
05/23/1996WO1996014836A1 Method and apparatus for gene therapy
05/23/1996WO1996014748A1 AMELIORATION OF HUMAN ERECTILE DYSFUNCTION BY TREATMENT WITH iNOS, AND RELATED NOS AGENTS
05/23/1996WO1996010580A3 Recombinant proteins of a pakistani strain of hepatitis e and their use in diagnostic methods and vaccines
05/23/1996DE19537774A1 Cell cultivation process and assembly for esp. lymphocyte cultures
05/23/1996CA2205414A1 Novel tumor suppressor gene, hic-1
05/23/1996CA2204886A1 Amelioration of human erectile dysfunction by treatment with inos, and related nos agents
05/23/1996CA2204870A1 Ribozyme analogs
05/23/1996CA2204669A1 Novel nucleic acid molecules comprising the prostate specific antigen (psa) promoter and uses thereof
05/23/1996CA2204629A1 In vitro induction of dopaminergic cells
05/23/1996CA2204597A1 Suppression of proteolytic activity by dysfunctional protease formation
05/23/1996CA2203934A1 Targeted t lymphocytes
05/23/1996CA2203654A1 Human stanniocalcin-alpha
05/23/1996CA2203565A1 Synthesis of peptide nucleic acids (pnas) and analogues via submonomer approach
05/22/1996EP0712930A2 A transgenic nonhuman animal model for diabetes
05/22/1996EP0712312A1 Suppression of inhibitors
05/22/1996EP0521914B1 A method for regulating neuron development and maintenance
05/22/1996EP0502081B1 Proliferative action of leukaemia inhibitory factor on satellite cells
05/22/1996CN1123038A Antisense oligonucleotides which combat aberrant splicing and methods of using the same
05/21/1996US5519118 Human MDM2 protein involved in human tumors
05/21/1996US5519117 Polypeptide sequences as anticarcinogenic agents
05/21/1996US5518880 X-linked severe combined immunodeficiency diseases
05/17/1996WO1996014435A1 USE OF NEURITE LOCALIZED mRNAs FOR MEDICAL DIAGNOSIS AND THERAPEUTICS
05/17/1996WO1996014420A1 Inducible cell ablation
05/17/1996WO1996014416A1 Method for enhancing the immunogenicity of an immunogenic compound or hapten, and use thereof for preparing vaccines
05/17/1996WO1996014412A2 cDNA ENCODING A BMP TYPE II RECEPTOR
05/17/1996WO1996014411A1 Methods for the diagnosis of glaucoma
05/17/1996WO1996014409A1 Production of recombinant peptides as natural hydrophobic peptide analogues
05/17/1996WO1996014401A1 Transgenic organisms and their uses
05/17/1996WO1996014394A1 Human dna ligase iii
05/17/1996WO1996014332A1 Retroviral vectors containing recombinant cmv-ie/hiv-tar/moloney murine leukemia virus long terminal repeats
05/17/1996WO1996014329A1 Sugar modified nucleosides and their use for synthesis of oligonucleotides
05/17/1996WO1996014328A1 Tumor necrosis factor-gamma
05/17/1996WO1996014077A1 Peripheral nervous system specific sodium channels, dna encoding therefor, crystallization, x-ray diffraction, computer molecular modeling, rational drug design, drug screening, and methods of making and using thereof
05/17/1996WO1996014074A1 Methods and devices for immunizing a host to tumor-associated antigens through administration of naked polynucleotides which encode tumor-associated antigenic peptides
05/17/1996WO1996014073A1 Treatment of urogenital cancer with boron neutron capture therapy
05/17/1996WO1996014061A1 Novel adenoviral vectors, packaging cell lines, recombinant adenoviruses and methods
05/17/1996WO1996010419A3 Composition comprising a recombinant virus expressing an antigen and a recombinant virus expressing an immunostimulatory molecule
05/17/1996WO1996002646A3 Growth control for cells encapsulated within bioartificial organs
05/17/1996CA2307311A1 Sugar modified nucleosides and their use for synthesis of oligonucleotides
05/17/1996CA2204619A1 Method for enhancing the immunogenicity of an immunogenic compound or hapten, and use thereof for preparing vaccines
05/17/1996CA2204511A1 Production of recombinant peptides as natural hydrophobic peptide analorues
05/17/1996CA2203935A1 Transgenic organisms and their uses
05/17/1996CA2203651A1 Dna ligase iv
05/15/1996EP0711831A2 Rabbit G protein coupled receptor
05/15/1996EP0711829A2 Recombinant alphavirus vectors
05/15/1996EP0711355A1 Method for diagnosing a disorder by determining expression of gage tumor rejection antigen precursors
05/15/1996EP0711345A1 B7-2: ctl a4/cd 28 counter receptor
05/15/1996EP0711149A1 Liposomal antisense methyl phosphonate oligonucleotides and methods for their preparation and use
05/15/1996EP0711127A1 Methods of preparing gas-filled liposomes
05/15/1996EP0343217B1 Isolation and preservation of fetal and neonatal hematopoietic stem and progenitor cells of the blood
05/15/1996CA2162799A1 G protein coupled receptor protein, production and use thereof
05/14/1996US5516653 Genetic engineering