Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
05/2002
05/16/2002WO2002022839A3 Internal ribosome entry sites (ires) of errantiviruses and uses thereof
05/16/2002WO2002018448A3 Percarboxylated polysaccharides, and a process for their preparation
05/16/2002WO2002012539A3 Nucleic acid constructs, vascular cells transformed therewith, pharmaceutical compositions and methods utilizing same for inducing angiogenesis
05/16/2002WO2002006502A3 Adenovirus vectors comprising introns
05/16/2002WO2002004026A3 Use of a retrotransposon as promoter in gene therapy
05/16/2002WO2002002743A3 The nip3 family of proteins
05/16/2002WO2002000680A3 Cationic steroid derivatives for gene delivery
05/16/2002WO2001096587A3 Methods for administering recombinant adeno-associated virus virions to humans previously exposed to adeno-associated virus
05/16/2002WO2001085789A3 Extracellular domain of ryk protein for regulating angiogenesis
05/16/2002WO2001081622A8 Diagnosis of diseases associated with dna repair
05/16/2002WO2001081599A3 Protection against environmental toxicity through manipulation of the processing of messenger rna precursors
05/16/2002WO2001079518A3 Codon optimisation for expression in retrovirus packaging cells
05/16/2002WO2001076638A3 Compositions for drug delivery
05/16/2002WO2001075109A3 Antagonist antibodies to ve-cadherin without adverse effects on vascular permeability
05/16/2002WO2001070953A3 Identification of modulators of the inteferon gamma signaling pathway and their use in restenosis treatment
05/16/2002WO2001068879A3 Human 1-aminocyclopropane-carboxylate synthase
05/16/2002WO2001068144A3 Biodegradable immunomodulatory formulations and methods for use thereof
05/16/2002WO2001068143A3 Immunomodulatory formulations and methods for use thereof
05/16/2002WO2001048163A3 Dioxygenases catalyzing the asymetric cleavage of beta-carotene
05/16/2002WO2001041739A3 Liposomes
05/16/2002WO2001040521A3 Nucleic acids containing single nucleotide polymorphisms and methods of use thereof
05/16/2002WO2001039802A9 Chimeric flavivirus vaccines
05/16/2002WO2001034636A9 Gridlock nucleic acid molecules, polypeptides, and diagnostic and therapeutic methods
05/16/2002WO2001032885A9 Human lipase
05/16/2002WO2001032685A8 Gene expression directed by a super-psa promoter
05/16/2002WO2001032128A9 Human chemokine beta-13
05/16/2002WO2001025408A9 Isolated dishevelled associated kinases, polynucleotides encoding the kinases, and methods of use thereof
05/16/2002US20020058795 Preferential particles for use in the transfer of macromolecules into cells; for use in gene therapy
05/16/2002US20020058638 Decreasing blood glucose levels, inhibiting PEPCK expression, decreasing blood insulin levels, decreasing insulin resistance, increasing insulin sensitivity, decreasing blood triglyceride levels or decreasing blood cholesterol levels
05/16/2002US20020058636 Ribozymes targeting the retroviral packaging sequence expression constructs and recombinant retroviruses containing such constructs
05/16/2002US20020058619 Ligand for vascular endothelial growth factor receptor
05/16/2002US20020058613 Modulating the expression or bioactivity of a bcl family member in a neural cell such that axonal growth occurs.
05/16/2002US20020058610 DNA (RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques; inhibiting such polypeptide for preventing and/or treating neoplasia; diagnostic assays
05/16/2002US20020058335 Compositions isolated from stromal cells and methods for their use
05/16/2002US20020058307 Nucleotide sequences coding preferential polypeptides; for use in diagnosis and treatment of infection, cancer, autoimmune diseases, allergies, blood disorders, crohn's disease, sepsis and psoriasis
05/16/2002US20020058288 Compound for use in the detection and prevention of parasitic infection of humans
05/16/2002US20020058267 Nucleotide sequences coding polypeptide for use in the treatment of alzheimer's disease
05/16/2002US20020058257 Diagnostic methods and gene therapy using reagents derived from the human metastasis suppressor gene KAI1
05/16/2002US20020058045 Constructing a fiber-mutant adenovirus vector by introducing a foreign peptide into the HI loop of the fiber of the virus.
05/16/2002US20020058036 Novel fibroblast growth factor and nucleic acids encoding same
05/16/2002US20020058024 Modulators of the function of receptors of the TNF/NGF receptor family and other proteins
05/16/2002US20020058022 Novel compounds
05/16/2002US20020058020 Isolated amphiphilic peptides derived from the cytoplasmic tail of viral envelope proteins
05/16/2002DE10054303A1 Analoga, Agonisten, Antagonisten und Varianten der Oxidoreduktase-Enzymaktivität des Makrophagen-Migrations-Inhibitions-Faktors (MIF) als Immunmodulatoren, Therapeutika, Diagnostika und Screening-Agenzien bei inflammatorischen und Immunerkrankungen Analogues, agonists, antagonists, and variants of the oxidoreductase enzyme activity of macrophage migration inhibitory factor (MIF) as immunomodulators, therapeutic agents, diagnostic and screening agents in inflammatory and immune diseases
05/16/2002CA2437942A1 Chimeric molecules to modulate gene expression
05/16/2002CA2433200A1 Use of a helminth for the in vivo delivery of a medicament
05/16/2002CA2428453A1 C. elegans genes involved in viability and/or reproduction and uses thereof
05/16/2002CA2428176A1 Use of the long pentraxin ptx3 for the treatment of diseases caused by an altered activation of the growth factor fgf-2
05/16/2002CA2428114A1 Apolipoprotein analogues
05/16/2002CA2426508A1 Modulators of bruton's tyrosine kinase and bruton's tyrosine kinase intermediates and methods for their identification and use in the treatment and prevention of osteoporosis and related disease states
05/16/2002CA2425980A1 Foggy
05/15/2002EP1205551A1 Growth hormone and growth hormone releasing hormone compositions
05/15/2002EP1205489A1 Polypeptide and nucleic acids encoding the same
05/15/2002EP1205191A1 Targeted modification of intracellular compounds
05/15/2002EP1204868A1 Cancer treatments and diagnostics utilizing rad51 related molecules and methods
05/15/2002EP1204764A2 Methods of screening for angiogenesis modulators
05/15/2002EP1204761A2 Targeted artificial gene delivery
05/15/2002EP1204760A2 Polynucleotides regulating the activation of the expression of a gene in the heart and its uses in gene therapy
05/15/2002EP1204754A2 Polynucleotides expressed in activated t-lymphocytes and proteins encoded thereby
05/15/2002EP1204753A2 Invasive bacteria based viral vaccines
05/15/2002EP1204752A2 Immunogenic polypeptides derived from moraxella catarrhalis and uses thereof
05/15/2002EP1204750A1 Basb126 polypeptide and polynucleotide from moraxella catarhalis
05/15/2002EP1204747A1 G protein-coupled receptor expressed in brain
05/15/2002EP1204745A2 Human p53 mutations and a genetic system in yeast for functional indentification of human p53 mutations
05/15/2002EP1204744A1 Isolated peptide of the horny layer and use thereof
05/15/2002EP1204742A2 Oligonucleotides for inhibiting the expression of human eg5
05/15/2002EP1204739A2 Enhancement of expression of a single-stranded, heterologous nucleotide sequence from recombinant viral vectors by designing the sequence such that it forms intrastrand base pairs
05/15/2002EP1204682A2 Compositions and methods for the treatment of tumors
05/15/2002EP1204678A1 Moraxella cattarrhalis basb114 antigens and uses thereof
05/15/2002EP1204674A2 Methods and compositions for inhibiting polypeptide accumulation associated with neurological disorders
05/15/2002EP1204430A2 Conjugates and methods for the production thereof, and their use for transporting molecules via biological membranes
05/15/2002EP1204428A2 Targeted lipid particles
05/15/2002EP1204407A2 Implantable active ingredient depot
05/15/2002EP1204321A2 Super-active porcine growth hormone releasing hormone analog
05/15/2002CN1349543A Membrane disruptive peptides covalently oligomerized
05/15/2002CN1349541A L-ribo-LNA analogues
05/14/2002US6388052 Amino acid sequence of nuclear factor of activated t lymphocytes, a transcription factor; immunomodulators
05/14/2002US6387701 Method of identifying tumor antigens that elicit a T-cell response
05/14/2002US6387700 Binding tryptophan-containing peptide to nucleic acid to make complex, then introducing complex to cell so that it is delivered across the cell membrane
05/14/2002US6387699 Antisense inhibition of A20 expression
05/14/2002US6387695 DNA pharmaceutical formulations comprising citrate or triethanolamine and combinations thereof
05/14/2002US6387682 Amino acid sequence of polypeptide with cysteine protease activity; treatment of bone disorders such as osteoporosis; anticarcinogenic agents; antitumor agents; antimetastasis agents
05/14/2002US6387670 Method for producing recombinant virus
05/14/2002US6387663 Fusion protein of collagen binding domain and angiogenesis modulating domain; treatment of cardiovascular disorders; antiischemic agents
05/14/2002US6387638 Heregulin variants
05/14/2002US6387629 Use of cathepsin S in the diagnosis and treatment of endometriosis
05/14/2002US6387619 Telomerase compositions and methods
05/14/2002US6387617 Proto-nucleozyme having catalytic activity in presence of non-nucleic cofactor which chemically interacts to provide missing component; viricides; anticarcinogenic agents
05/14/2002US6387397 Polymerized liposomes targeted to M cells and useful for oral or mucosal drug delivery
05/14/2002US6387396 In gene therapy and in in vitro and in vivo transfection
05/14/2002US6387390 Compositions and methods for enhancing receptor-mediated cellular internalization
05/14/2002US6387369 Cardiac muscle regeneration using mesenchymal stem cells
05/14/2002US6387368 Hybrid adenovirus-AAV virus and methods of use thereof
05/14/2002US6387367 Human mesenchymal stem cells
05/14/2002US6387366 Reducing the biological activity of tissue factor, tf; bone marrow cells; antisense oligonucleotide or ribozyme which inhibits expression of tissue factor (tf) or an antibody that binds to and inhibits tf
05/14/2002CA2023899C Anti-sense oligonucleotide sequence, anti-rna messenger of tnf alpha, process for its preparation, use as medicament and pharmaceutical composition
05/10/2002WO2002036829A2 Methods of diagnosing, preventing and treating neurological disorders and neuronal injuries
05/10/2002WO2002036810A2 Antisense modulation of talin expression
05/10/2002WO2002036790A2 Influenza virus vector for infection of dendritic cells
05/10/2002WO2002036780A2 Stearoyl-coa desaturase gene promoter