Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
11/2003
11/11/2003US6646006 Enhancement of vascular function by modulation of endogenous nitric oxide production or activity
11/11/2003US6645937 Methods using persephin and related growth factors
11/11/2003US6645760 Negative strand RNA viral vector having autonomous replication capability
11/11/2003US6645751 Nucleic acid isolated from Tetrahymena which codes for a triterpenoid cyclase, its production, and use
11/11/2003US6645740 Nucleic acids encodings equine GM-CSF
11/11/2003US6645500 Method for down-regulating osteoprotegerin ligand activity
11/11/2003US6645493 Composition containing anti-MIF antibody
11/11/2003US6645492 For diagnosis and therapy of susceptibility to atopic allergy, asthma
11/11/2003US6645484 Endothelial cell transmembrane tyrosine kinase ligand
11/06/2003WO2003091734A1 Diagnostic and therapeutic use of ensadin-0477 gene and protein for neurodegenerative diseases
11/06/2003WO2003091456A1 A dna enzyme to inhibit plasminogen activator inhibitor-1
11/06/2003WO2003091442A1 Improved chimeric glycoproteins and pseudotyped lentiviral vectors
11/06/2003WO2003091432A1 Circular dumbbell decoy oligodeoxynucleotides (cdodn) containing dna bindings sites of transcription
11/06/2003WO2003091413A2 Expression of polypeptides in chloroplasts, and compositions and methods for expressing same
11/06/2003WO2003091397A2 Methods and compositions for regulating cellular signaling
11/06/2003WO2003091387A2 Non-invasive delivery of polypeptides through the blood-brain barrier, and in vivo selection of endocytotic ligands
11/06/2003WO2003091271A1 Alternatively spliced nucleic acid molecules
11/06/2003WO2003090778A2 Dna vaccine combined with an inducer of tumor cell apoptosis
11/06/2003WO2003090689A2 Neurodegenerative disorder treatment using gdnf secreting neural cells
11/06/2003WO2003090676A2 Immunogenic agent therapy using plasmapheresis or exchange transfusion
11/06/2003WO2003090512A2 Regeneration of endogenous myocardial tissue by induction of neovascularization
11/06/2003WO2003080112A3 Imidazoquinolineamines as adjuvants in hiv dna vaccination
11/06/2003WO2003072711A3 Method of using modified oligonucleotides for hepatic delivery
11/06/2003WO2003057007A3 System for monitoring bacterial tumor treatment
11/06/2003WO2003055983A3 Targeted retrograde gene delivery to motor neurons
11/06/2003WO2003054541A3 Inhibition of tristetraproline for protection of the heart from cardiac injuries
11/06/2003WO2003038112A3 A composition and method to alter lean body mass and bone properties in a subject
11/06/2003WO2003030934A3 Cpg formulations and related methods
11/06/2003WO2003025167A3 Cultured stromal cells and uses thereof
11/06/2003WO2003025147A3 Novel polynucleotides and proteins encoded thereby
11/06/2003WO2003023021A3 Methods for producing an active constituent of a pharmaceutical or a diagnostic agent in an mdck cell suspension culture
11/06/2003WO2003016515A3 Regulation of human glycerol-3-phosphate acyltransferase-like protein
11/06/2003WO2003015714A3 Compositions and therapeutic methods for viral infection
11/06/2003WO2003008555A3 Cellular targeting poly(ethylene glycol)-grafted polymeric gene carrier
11/06/2003WO2003004064A3 Products for treating ovarian cancers and for preventing relapses
11/06/2003WO2003001983A3 Methods for diagnosing and treating a disease mediated by decreased mmp-2 function
11/06/2003WO2002098916A3 Transcriptional regulator of genes involved in the control of cell growth or cell proliferation. use of said regulator as a therapeutic or diagnostic agent
11/06/2003WO2002096939A3 Adenovirus protein ix, its domains involved in capsid assembly, transcriptional activity and nuclear reorganization
11/06/2003WO2002094845A3 Method for stabilising of nucleic acids
11/06/2003WO2002094313A3 Vaccine composition
11/06/2003WO2002079401A3 Novel rgs9 protein binding interactions and methods of use thereof
11/06/2003WO2002079386A3 Isolated human ras-like proteins, nucleic and acid molecules encoding these human ras-like proteins, and uses thereof
11/06/2003WO2002076482B1 USE OF IKK-β INHIBITORS AND METHOD FOR DISCOVERY OF SAID INHIBITORS
11/06/2003WO2002063025A3 Muscle-directed gene therapy with aav-1 and aav-6 vectors
11/06/2003WO2002062945A3 Compositions and methods relating to lung specific genes and proteins
11/06/2003WO2002059270A8 Methods and compositions for expressing polynucleotides specifically in smooth muscle cells in vivo
11/06/2003WO2002051980A3 In vitro-derived adult pluripotent stem cells and uses therefor
11/06/2003WO2002046475A3 Method of detecting and treating tuberous sclerosis complex associated disorders
11/06/2003WO2002045708A9 Use of zwitterionic polysaccharides for the specific modulation of immune processes
11/06/2003WO2002030257A3 Normalization of defective t cell responsiveness through manipulation of thymic regeneration
11/06/2003WO2002024891A9 B7-like molecules and uses thereof
11/06/2003WO2002009639A3 Methods and pharmaceutical compositions for healing wounds
11/06/2003WO2002005749A3 Crf2 ligands in combination therapy
11/06/2003WO2002004952A3 Diagnostic and therapeutic methods based on the l1 adhesion molecule for ovarian and endometrial tumors
11/06/2003WO2001080633A8 Surfactant protein d for the prevention and diagnosis of pulmonary emphysema
11/06/2003WO2000026247A8 Ikaros isoforms and mutants
11/06/2003WO2000023569A8 Surfactant protein d for the prevention and diagnosis of pulmonary emphysema
11/06/2003US20030208783 Transcriptional activator fusion proteins which comprises both tetracycline controlled transactivator proteins and reverse tetracycline transactivator proteins
11/06/2003US20030208780 Useful in preparing recombinant cells for diagnosis and therapy of human tumors
11/06/2003US20030208059 Gene therapy approaches to supply apolipoprotein A-I agonists and their use to treat dyslipidemic disorders
11/06/2003US20030208058 B7-like polypeptides and polynucleotides
11/06/2003US20030207841 Novel nucleoside and oligonucleotide analogues
11/06/2003US20030207840 Solid tumors and other conditions related to angiogenesis, including wounds, bone fractures, follicular development, ischemia, retinopathy, psoriasis, and rheumatoid arthritis are treated or detected with reagents which either detect,
11/06/2003US20030207838 Use of pro-apoptotic factors in treatment of atherosclerosis
11/06/2003US20030207836 Ovo nucleotide immuno-stimulant. The VAF contains one or more DNA constructs, each having a DNA molecule and a vector. Each of the DNA molecule contains one or more genes or gene fragments, each encoding an antigenic peptide of an avian
11/06/2003US20030207835 Nucleic acid and corresponding protein named 158P1D7 useful in the treatment and detection of bladder and other cancers
11/06/2003US20030207834 The present invention relates to methods and compositions containing oligonucleotides suitable for administration to humans and other mammals.
11/06/2003US20030207832 Inducible gene expression constructs and methods of inducing gene expression using a combination of inducing agents.
11/06/2003US20030207830 Mutant NDP kinases for antiviral nucleotide analog activation and therapeutic uses thereof
11/06/2003US20030207829 methods for treating cancer by administering an effective amount of a modified Herpes simplex virus.
11/06/2003US20030207828 DNA whose expression level fluctuates in leukocytes of IgA nephropathy patients in comparison with leukocytes of healthy persons, a process for isolating the DNA, a novel protein encoded by the DNA, an antibody recognizing the protein,
11/06/2003US20030207827 Novel secreted polypeptide, termed osteoprotegerin, which is a member of the tumor necrosis factor receptor superfamily and is involved in the regulation of bone metabolism. Also disclosed are nucleic acids encoding osteoprotegerin,
11/06/2003US20030207804 Peptide nucleic acids exhibit enhanced cellular uptake and distribution. The peptide nucleic acids of the invention comprise naturally-occurring nucleobases and non-naturally-occurring nucleobases attached to a polyamide
11/06/2003US20030207451 Methods, compositions, and kits for enhancing oligonucleotide-mediated nucleic acid sequence alteration using compositions comprising a histone deacetylase inhibitor, lambda phage beta protein, or hydroxyurea
11/06/2003US20030207446 Infectious papillomavirus pseudoviral particles
11/06/2003US20030207435 Have increased anti-coagulation activity and resistance to inactivation by serpins
11/06/2003US20030207434 Phosphodiesterases
11/06/2003US20030207403 For diagnosis or treatment of diseases with beta 10 polypeptides and alpha 2/ beta 10 heterodimers or their respective binding agents, such as thyroid gland disorders
11/06/2003US20030207400 Double stranded DNA of target sequence(s) bound non-covalently to a sequence specific polyamide (SSP) moiety having a ligand moiety linked covalently to said polyamide; polyamide contains N-methylpyrrole or N-methylimidazole groups
11/06/2003US20030207318 Kinesin-like motor protein
11/06/2003US20030207317 Novel nucleic acid isolated from Tetrahymena which codes for a triterpenoid cyclase, its production, and use
11/06/2003US20030207316 Transmembrane serine protease overexpressed in ovarian carcinoma and uses thereof
11/06/2003US20030207301 Assay for the detection of factors that modulate the expression of INGAP
11/06/2003US20030207293 Cryptic-like secreted protein
11/06/2003US20030207262 Compounds, methods of screening, and in vitro and in vivo uses involving anti-apoptotic genes and anti-apoptotic gene products
11/06/2003US20030206926 Characterized by the loss of its capability to reproductively replicate in human cell lines.
11/06/2003US20030206921 Chlamydia antigens and corresponding DNA fragments and uses thereof
11/06/2003US20030206911 Modifying selected antibodies with biotin and streptavidin, conjugating these antibodies with an effector molecule, and delivering the conjugated effector to an intracellular target
11/06/2003US20030206910 Poloxamer 188, Poloxamer 237, Poloxamer 338, Poloxamer 124, Poloxamer 401, Tetronic 904, Tetronic 908, Tetronic 1107 or Tetronic 90R4; especially for treating chronic hepatitis and cancer
11/06/2003US20030206908 Human paris-1 antigen and nucleic acids: diagnostic and therapeutic uses
11/06/2003US20030206891 Constructs comprising DNA sequences derived from sequences encoding the proteins FRAP, Tor1, Tor2 and other proteins capable of binding to FKBP:rapamycin
11/06/2003US20030206889 Methods of treating anemia using recombinant adeno-associated virus virions
11/06/2003US20030206888 Herpes simplex virus strains
11/06/2003US20030206886 Neutralization of immune suppressive factors for the immunotherapy of cancer
11/06/2003CA2484223A1 Use of human neural stem cells secreting gdnf for treatment of parkinson's and other neurodegenerative diseases
11/06/2003CA2483980A1 Non-invasive delivery of polypeptides through the blood-brain barrier, and in vivo selection of endocytotic ligands
11/06/2003CA2483551A1 Immunogenic agent therapy using plasmapheresis or exchange transfusion
11/06/2003CA2483505A1 Circular dumbbell decoy oligodeoxynucleotides (cdodn) containing dna bindings sites of transcription
11/06/2003CA2483431A1 Alternatively spliced nucleic acid molecules
11/06/2003CA2483337A1 Expression of polypeptides in chloroplasts, and compositions and methods for expressing same