Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
03/2005
03/24/2005US20050064596 Buffer solution for electroporation and a method comprising the use of the same
03/24/2005US20050064595 Silencing gene expression by delivering nucleic acid-lipid particles comprising a siRNA molecule to a cell; stable nucleic acid-lipid particles (SNALP)
03/24/2005US20050064572 Lipid kinase
03/24/2005US20050064558 Chimeric polypeptide comprising functional differentially spliced interleukin receptor and b-cell differentiation factor for enhancing expression of interferon inducible protein (IP-10) and macrophage inflammarory proteins for use in treatment of viral diseases
03/24/2005US20050064542 Nucleic acid expressed in the hypothalamus or muscle tissue in obese animals
03/24/2005US20050064541 For immunoregulation and/or treatment of inflammation; muteins,
03/24/2005US20050064534 Using microscopic systems to monitoring f-actin and myosin activity in cells; monitoring biopolymer transfer between membrane walls
03/24/2005US20050064527 Identifying modulator of activity of newly identified multiple antibiotic resistance (mar) locus regulated (NIMR) gene products; microbiocides; bactericides
03/24/2005US20050064522 EG-VEGF nucleic acids and polypeptides and methods of use
03/24/2005US20050064491 Transport protein for use as tool in identifying modulator for treatment of sleep, nervous suystem, anixety, eating, cardiovascular and pain disordere
03/24/2005US20050064475 Using type II membrane glycoprotein (4F2hc) as tool in identifying modulator which inhibit transcription in tumor cells; gene expresion inhibition and antitumors agents
03/24/2005US20050064460 Emulsion compositions
03/24/2005US20050064458 Nucleotide sequences coding membrane protein for use in diagnosis, prevention and treatnment of cell proliferative, nervous system, metabolic and inflammatory disorders
03/24/2005US20050064453 Kit which utilizes interleukin-1-related gene as diagnostic/prognostic tool in detection of urogenital disorders; genomics and bioinformatics
03/24/2005US20050064440 Using single nucleotide polymorphism in contactin-2 (CNTN-2) and kinesin-7 (CENP-E) genes as diagnostic indicators of cell proliferative disorders; antitumor agents; ribozymes and tumor treatment; RNA interference
03/24/2005US20050064416 Methods for diagnosing and treating heart disease
03/24/2005US20050064413 Oncogenic protein for use in diagnosis, prevention and treatment of cell proliferative disorders of nervous ystem
03/24/2005US20050064407 Bcl-2 dnazymes
03/24/2005US20050064405 Nucleotide sequences coding metallo beta -lactamase (VDJ protein) for use as tool in diagnosis, treatment and prognosis of cell proliferative disorders
03/24/2005US20050064404 Regulation of human serotonin-like g protein-coupled receptor
03/24/2005US20050064390 Transgenic cell line expressing chemokine receptor for use as model in identifying modulators wich prevent/block viral infection; viricides
03/24/2005US20050064023 Lipid linked to a delivery, targeting or stabilising moiety (DTS moiety) via a linker which is stable in biological fluid and which is unstable in defined conditions, forms a complex with a therapeutic agent; for non-viral gene transfer
03/24/2005US20050063993 For treatment of cancer/tumors/fungal/viral infections; tumor associated antigens; genetic engineering
03/24/2005US20050063985 Method and compositions for immunization with the pseudomonas v antigen
03/24/2005US20050063982 GRP94-based compositions and methods of use thereof
03/24/2005US20050063971 Monoclonal or humanized antibodies that immunospecifically bind to FGF-CX or any derivative, variant, mutant, polypeptide fragment, polynucleotide or antibody
03/24/2005US20050063961 Hematopoietic stem cells and endothelial progenitor cells; express the cell surface antigen CD31; delivering transgenes to the eye for cell-based gene therapy; treating ocular diseases such as retinopathy
03/24/2005US20050063959 By transfection with an an osteo-/chondro-inducible transcription factor gene such as Cbfa1, Dlx-5, Bapx1, Msx2, Scleraxis, or Sox9, and allowing the cells to differentiate and proliferate on a scaffold; implants
03/24/2005US20050063958 Ex vivo gene therapy for HIV; formulation of CD34+ hematopoietic cells transduced with a viral construct which expresses an anti-HIV agent such as a ribozyme
03/24/2005US20050063953 Adenoviral vector with replication-dependent transgene expression
03/24/2005US20050063950 Cell-targeting ligand (e.g. transferrin) noncovalently bound directly to a virus; less inactivation of ligand than with conjugation; tissue targeted therapy; sensitizing cancer cells prior to chemotherapy or radiotherapy
03/24/2005US20050063947 Method for treating cancer in humans
03/24/2005US20050063943 Conjugated of hydroxyalkyl starch and an active agent
03/24/2005US20050063905 Administering a RADIONUCLIDE COMPLEXED WITH A CHELATING AGENT SUCH AS MACROCYCLIC AMINOPHOSPHONIC ACID, or tetraazacyclododecanetetramethylenephosphonic acid (DOTMP); polycythemia vera, macroglobulinemia (Waldenstrom syndrome), megakaryocytic myelosis, malignant histiocytosis
03/24/2005DE10337770A1 Endothelial-cell specific gene-transfer system, useful for treating tumors, comprises virus that includes vascular endothelial growth factor in its capsid
03/24/2005CA2551022A1 Polyethyleneglycol-modified lipid compounds and uses thereof
03/24/2005CA2539300A1 Inhibitors of pace4 for the treatment of arthritis
03/24/2005CA2539132A1 Methods for identifying modulators of protein kinase c-epsilon (pkc.epsilon.) and method of treatment of aberrant glucose metabolism associated therewith
03/24/2005CA2538495A1 The use of eukaryotic genes affecting chromatin separation for diagnosis and treatment of proliferative diseases
03/24/2005CA2538461A1 The use of eukaryotic genes affecting spindle formation or microtubule function during cell division for diagnosis and treatment of proliferative diseases
03/24/2005CA2538442A1 Eukaryotic genes for modulating cell cycle progression
03/24/2005CA2537931A1 Multi-antigen vectors for melanoma
03/24/2005CA2536931A1 Method of preparation of pharmaceutically grade plasmid dna
03/24/2005CA2526720A1 Recombinant carrier molecule for expression, delivery and purification of target polypeptides
03/23/2005EP1516932A1 Poxvirus with targeted infection specificity
03/23/2005EP1516597A1 Drug eluting stent
03/23/2005EP1516064A2 Methods of using 46828, a human acyl-coa synthetase
03/23/2005EP1516063A2 Nucleotide and amino acid sequences relating to respiratory diseases and obesity
03/23/2005EP1516057A2 Nucleic acid isolated from the 5' non translated region (5'ntr) end of the human fgf-1 gene having ires activity
03/23/2005EP1515988A1 Dna sequence and recombinant production of the grass pollen allergen phl p4
03/23/2005EP1515752A1 Ace2 activation for treatment of heart, lung and kidney disease and hypertension
03/23/2005EP1515747A2 Immunogenic agent therapy using plasmapheresis or exchange transfusion
03/23/2005EP1515743A2 Use of osteoprotegerin for the prevention and/or treatment of fibrosis/sclerosis
03/23/2005EP1515742A2 Genes involved in regulating angiogenesis, pharmaceutical preparations containing same and applications thereof
03/23/2005EP1401871B1 Immunological binding molecules inhibiting the syncytial fusion of trophoblast cells
03/23/2005EP1345618B1 Chlorzoxazone for the treatment of psoriasis
03/23/2005EP1297119B9 Method for introducing nucleic acids and other biologically active molecules into the nucleus of higher eukaryotic cells by means of an electrical current
03/23/2005EP1228373B1 Diagnosis and therapy of cancer using sgp28-related molecules
03/23/2005EP1181382B1 Recombinant adenoviral vectors expressing chimeric fiber proteins for cell specific infection and genome integration
03/23/2005EP1114166B1 Method for down-regulating osteoprotegerin ligand activity
03/23/2005EP0981636B1 Lentivirus-based gene transfer vectors
03/23/2005EP0845005B1 Traf inhibitors
03/23/2005EP0804613B1 Dap-2 tumor suppressor gene, protein encoded thereby and use of said gene and protein
03/23/2005EP0574579B1 Dna encoding a human 5-ht 1f receptor and uses thereof
03/23/2005CN1599797A Intact minicells as vectors for DNA transfer and gene therapy in vitro and in vivo
03/23/2005CN1597957A A group nucleodite sequence of anti-hepatitis virus C infection and preventing and curing hepatitis virus C and its segment and application
03/23/2005CN1597956A Trans menbrance type and secretory type HIV Gag antigen code gene and AIDS vaccine containing said gene
03/23/2005CN1597939A Multifunctional anticancer recombined adenovirus
03/23/2005CN1597694A Meningococcal antigens
03/23/2005CN1596977A Anti gonadoliberin resisting hormone nucleic acid vaccine and its preparation method
03/23/2005CN1194093C Bacterial plasmids
03/23/2005CN1193756C SGK2 and SGK3 used as diagnostic and therapeutic targets
03/22/2005US6870046 Antisense modulation of interferon gamma receptor 2 expression
03/22/2005US6870032 Assay for the diagnosis of flaviviral infection using antibodies with high affinity for NS1 protein of flavivirus in hexameric form
03/22/2005US6870030 Nucleotide sequences coding polypeptide for use in the treatment and diagnosis of nervous system and tumor disorders
03/22/2005US6870027 Expression of PUMP-1 protease (matrix metalloprotease 7) and the detected proteases are themselves specifically over-expressed in certain cancer, so their presence may serve for early detection of associated ovarian cancer
03/22/2005US6869936 Drug delivery via adenovirus capsids; for treatment of rheumatoid arthritis
03/22/2005US6869935 Gene Therapy for proliferative vitreoretinopathy
03/22/2005US6869794 A packaging cell line capable of complementing recombinant adenoviruses based on serotypes from subgroup B, preferably adenovirus type 35. The cell line is preferably derived from primary, diploid human cells transformed by adenovirus E1
03/22/2005US6869789 Heparinase III and uses thereof
03/22/2005US6869779 Nucleic acid sequence for potentiating the expression of useful gene and method therefor
03/22/2005US6869777 Mini-dystrophin nucleic acid sequences
03/22/2005US6869605 Anticarcinogenic agents
03/22/2005US6869568 Functional assay of high-density lipoprotein
03/17/2005WO2005024061A2 Compounds and methods for modulation of dna replication
03/17/2005WO2005024059A2 Methods for identifying compounds for inhibiting fever
03/17/2005WO2005024033A2 Nucleotide sequences promoting the trans-membrane transport of nucleic acids
03/17/2005WO2005024032A2 Targeting adenoviral vectors to dendritic cells
03/17/2005WO2005024016A1 Mutant hsv vector useful in treating human glioma
03/17/2005WO2005023996A2 METHODS OF INDUCING THE EXPRESSION OF BONE MORPHOGENETIC PROTEINS (BMPs) AND TRANSFORMING GROWTH FACTOR-β PROTEINS (TGF-βs) IN CELLS
03/17/2005WO2005023994A2 Modified oligonucleotides for telomerase inhibition
03/17/2005WO2005023990A2 Trans-splicing mediated photodynamic therapy
03/17/2005WO2005023313A1 Lentivirus vector-based approaches for generating an immune response to hiv humans
03/17/2005WO2005023312A2 Methods for transfecting cells using dna minor groove binding agents
03/17/2005WO2005023311A2 Novel targets for the treatment of retina diseases
03/17/2005WO2005023292A1 Methods of treating restenosis
03/17/2005WO2005023180A2 Method for detecting cancer cells and monitoring cancer therapy
03/17/2005WO2005023083A2 Compositions and methods for the treatment of severe acute respiratory syndrome (sars)
03/17/2005WO2004101801A3 Improved method for producing non-pathogenic helper virus-free preparations of herpes virus amplicon vectors, the helper virus & the cells used in this method, the corresponding generic tools, as well as the applications of these non-pathogenic amplicons vectors
03/17/2005WO2004083383A3 Globin variant gene methods and compositions