Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
12/2007
12/11/2007US7306800 Monoclonal antibody that recognizes a human 8F4 polypeptide, wherein 8F4 polypeptide: is an inducible T cell costimulatory molecule; occurs on two-signal-activated CD4+ T lymphocytes from human peripheral blood; dimer of two peptide chains
12/11/2007US7306797 Use of a compound antagonist of ESM-1 protein for producing a medicine for treating cancer
12/11/2007US7306794 Methods and compositions for the treatment of defects in lipoprotein metabolism
12/11/2007US7306793 Defective recombinant adenoviruses expressing cytokines for antitumor treatment
12/11/2007US7306792 In particular, invention relates to alphavirus-based, preferably Sindbis virus-based, vectors and to non-alphavirus-based vectors, which have a preferential affinity for high affinity laminin receptors
12/11/2007CA2188463C Pharmaceutical compositions containing activated protein c-resistant factor v for the treatment of bleeding disorders
12/11/2007CA2171618C Purine nucleoside phosphorylase gene therapy for human malignancy
12/06/2007WO2007140410A2 Low-density lipoprotein receptor 6 (lrp6) as a mammary stem cell marker and related methods
12/06/2007WO2007140000A2 Administration of the reg1 anticoagulation system
12/06/2007WO2007139970A2 Men1 gene for diagnosis and treatment of diabetes
12/06/2007WO2007139178A1 Therapeutic agent for alzheimer's disease
12/06/2007WO2007139150A1 ANTI-INFLUENZA VIRAL AGENT COMPRISING TNF-α INHIBITOR
12/06/2007WO2007139120A1 AMYLOID-β CLEARANCE ENHANCER
12/06/2007WO2007138810A1 Prophylactic/therapeutic agent for neurodegenerative disease
12/06/2007WO2007138253A1 Screening method
12/06/2007WO2007138193A1 Treatment of an infection by an rna virus due to an rna dependent rna polymerase
12/06/2007WO2007138104A1 Expression vectors comprising the hs1 promoter of the vav1 oncogene and use thereof for the preparation of pharmaceutical compositions intended for somatic gene therapy
12/06/2007WO2007137414A1 Overexpression of integrin linked kinase (ilk) to improve post-infarct remodeling
12/06/2007WO2007120170A9 Compositions and methods for treating gram positive bacterial infection in a mammalian subject
12/06/2007WO2007055704A3 Immunostimulatory properties of oligonucleotide-based compounds comprising modified immunostimulatory dinucleotides
12/06/2007WO2007014077A3 Rnai modulation of the rho-a gene and uses thereof
12/06/2007WO2005089231A3 Enhanced activity of hiv vaccine using a second generation immunomodulatory oligonucleotide
12/06/2007WO2005033277A3 Methods of modulating cell cycle and cell signaling pathways using biliverdin reductase
12/06/2007WO2003023001A3 Novel proteins and nucleic acids encoding same
12/06/2007US20070281901 Rnai-mediated inhibition of tumor necrosis factor alpha-related conditions
12/06/2007US20070281900 COMPOSITIONS AND METHODS FOR LIPID AND POLYPEPTIDE BASED siRNA INTRACELLULAR DELIVERY
12/06/2007US20070281899 COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF Eg5 GENE
12/06/2007US20070281896 Novel compositions and methods in cancer
12/06/2007US20070281890 Fibroblast Growth Factor-13
12/06/2007US20070281888 having an activity of growing vascular endothelial cells, promoting transcription form c-fos promoter, promoting transciption from VEGF promoter and/or an angiogenic activity; a polynucleotide encoding this polypeptide; for treating obstructive arteriosclerosis, peripheral vascular disorder, angina
12/06/2007US20070281306 Novel 15571, 2465, 14266, 2882, 52871, 8203 and 16852 molecules and uses therefor
12/06/2007US20070280963 Method for Producing Non-Pathogenic Helper Virus-Free Preparations of Herpes Virus Amplicon Vectors, the Helper Virus and the Cells Used in this Method, the Corresponding Generic Tools, as Well as the Applications of These Non-Pathogenic Amplicon Vectors
12/06/2007US20070280961 cDNA corresponding to the antigenome of nonsegmented negative strand RNA viruses and process for the production of such viruses
12/06/2007US20070280948 low density lipoprotein receptor-related protein 5 (LRP5) is a cell surface marker for somatic mammary stem cells and mammary tumor stem cells; enriching somatic mammary stem cells by contacting with anti(LRP5) antibody; selecting cells that bind to the antibody
12/06/2007US20070280947 Tie Receptor and Tie Ligand Materials and Methods for Modulating Female Fertility
12/06/2007US20070280925 Combination enzyme replacement, gene therapy and small molecule therapy for lysosomal storage diseases
12/06/2007US20070280908 Treatment of diabetes with synthetic beta cells
12/06/2007US20070280907 Adult bone marrow cell transplantation to testes creation of transdifferentiated testes germ cells, leydig cells and sertoli cells
12/06/2007US20070280906 Method to generate mirrored adenoassociated viral vectors
12/06/2007US20070280905 Prognosis and Systemic Therapy for Treating Malignancy
12/06/2007US20070280903 T1 Receptor-Like Ligand II and Uses Thereof
12/06/2007US20070280902 Method for treating eye disease or conditions affecting the posterior segment of the eye
12/06/2007US20070280880 Method for cell-specific targeting
12/06/2007CA2654033A1 Therapeutic agent for alzheimer's disease
12/06/2007CA2653910A1 Treatment of an infection by an rna virus due to an rna dependent rna polymerase
12/05/2007EP1862546A1 Enhanced virus-mediated dna transfer
12/05/2007EP1862544A1 Polypeptides capable of eliciting an immune reaction against cancer
12/05/2007EP1862472A2 Chlamydia protein, gene sequence and uses thereof
12/05/2007EP1862470A1 Element retained in blood showing degradability selectively in tumor tissue
12/05/2007EP1861491A1 Flavivirus replicon constructs for tumour therapy
12/05/2007EP1861118A2 Identification of surface-associated antigens for tumor diagnosis and therapy
12/05/2007EP1492876B1 Cationic amphiphiles for intracellular delivery of therapeutic molecules, composition, process and use thereof
12/05/2007EP1381393B1 Microparticle protection of therapeutic agents
12/05/2007EP1339440B1 An implantable or insertable therapeutic agent delivery device
12/05/2007EP0941252B1 Anti-p53 single-chain antibody fragments and their uses
12/05/2007EP0932418B1 Method for recombinant adeno-associated virus-directed gene therapy
12/05/2007EP0931149B1 A novel haemopoietin receptor and genetic sequences encoding same
12/05/2007EP0760675B2 Compositions comprising dna damaging agents and p53
12/05/2007CN101084237A Ubiquitin or gamma-crystalline conjugates for use in therapy, diagnosis and chromatography
12/05/2007CN101084232A Antiviral oligonucleotides
12/05/2007CN101082042A Application of artificial reconstructed defect type human 3-type adenovirus
12/05/2007CN101081238A Gene therapy for preventing and curing highly pathogenic bird flu and enteron disease
12/05/2007CN100352930C Vaccines immunotherapeutics and method for using the same
12/05/2007CN100352929C Bitarget fibroblast growth factor acceptor and transgene carrier of integrated element
12/05/2007CN100352924C BASB 111 polypeptide and polynucleotide from moraxella cathraahalis
12/05/2007CN100352923C Nucleic acids, polypeptides, and methods for modulating apoptosis
12/05/2007CN100352922C SiRAN and expression carrier for inhibiting human VEGF gene expression and their pharmaceutical use
12/05/2007CN100352921C Compositions and methods for identifying antigens which elicit an immune response
12/05/2007CN100352828C SMAD4 gene expression-inhibiting SiRNA, its encoding sequence and application
12/05/2007CN100352513C Novel mucous membrane vaccine for newcastle disease and its construction method
12/05/2007CN100352512C Recombinant human co-stimulatory molecule bacilli-calmette-guerin strain and process for making same
12/05/2007CN100352511C Vaccination by topical application of genetic vectors
12/05/2007CN100352427C Biodegradable microparticles for controlled release administration, with purified amylopectin-based starch of reduced molecular weight
12/04/2007US7304138 Therapeutic and diagnostic methods and compositions based on jagged/notch proteins and nucleic acids
12/04/2007US7304042 Potent inhibition of influenza virus by specifically designed short interfering RNA
12/04/2007US7304040 Suppression of post-transplant arteriosclerosis
12/04/2007US7303910 Retroviral vectors comprising a functional splice donor site and a functional splice acceptor site
12/04/2007US7303895 Choline transport like (CTL) membrane proteins involved in choline transport
12/04/2007US7303890 Proteins, genes encoding them and method of using the same
12/04/2007US7303885 For treating or detecting MIF (macrophage migration inhibitor factor) related diseases by detecting MIF/Jab1 (c-Jun activation domain binding protein) interactions; complex MIF in natural association with Jab1 and optionally another protein
12/04/2007US7303868 Mutant bank
12/04/2007CA2263705C Novel sandwich liposome complexes comprising a biologically active agent
12/04/2007CA2201120C Polyethylene glycol modified ceramide lipids and liposome uses thereof
11/2007
11/29/2007WO2007137303A2 Permeability of blood-brain barrier
11/29/2007WO2007137301A2 Modulation of chrebp expression
11/29/2007WO2007137239A2 Treatment of protein misfolding
11/29/2007WO2007137237A2 Treatment of protein misfolding
11/29/2007WO2007137156A2 Rnai modulation of aha and therapeutic uses thereof
11/29/2007WO2007137149A2 Use of cathepsin k antagonists in bone production
11/29/2007WO2007137117A2 Aptamer-directed drug delivery
11/29/2007WO2007136989A2 Compounds and methods for modulating expression of dgat2
11/29/2007WO2007136988A2 Compounds and methods for modulating expression of gccr
11/29/2007WO2007136910A2 Eimmunotherapy for immune suppressed patients
11/29/2007WO2007136857A2 Hox compositions and methods
11/29/2007WO2007136758A2 Sirna inhibition of p13k p85, p110, and akt2 and methods of use
11/29/2007WO2007136707A2 Methods and compositions related to eosinophil regulation
11/29/2007WO2007136107A1 Method of constructing gene transport support
11/29/2007WO2007135426A2 Treatment of neurodegeneratives diseases
11/29/2007WO2007135284A1 Use of cells derived from adipose tissue for the preparation of an anti-tumour medicament
11/29/2007WO2007135164A1 Nanoparticles of chitosan and hyaluronan for the administration of active molecules