A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
12/2009
12/08/2009	US7629322 carries capsid protein mutations resulting in a reduced heparin binding function, suitable for gene therapy by systemic application, since transduction of the liver is eliminated; gene therapy in a heart muscle tissue of a patient
12/08/2009	US7629321 Oligoribonucleotides and ribonucleases for cleaving RNA
12/08/2009	US7629310 RhoB as a suppressor of cancer cell growth, cell transformation, and metastasis
12/08/2009	US7629168 Reversibly immortalized human pancreatic islet cell line containing an hTERT gene and an SV40T gene each interposed between a pair of LoxP sequences, characterized in that it is capable of producing insulin and enhancing expression of insulin after excising the hTERT gene and the SV40T gene, NAKT-13
12/08/2009	US7629145 Expression vector comprising nucleotide sequences coding endothelial growth factor protein for use in prevention and treatment of cell proliferative and eye disorders
12/08/2009	US7629003 Esters of L-carnitine of alkanoyl L-carnitines useful as cationic lipids for the intracellular delivery of pharmacologically active compounds
12/08/2009	US7628990 Immunomodulatory compositions containing an immunostimulatory sequence linked to antigen and methods of use thereof
12/08/2009	US7628989 Methods of inducing an immune response
12/08/2009	US7628988 Induce cell differentiation; process control
12/08/2009	US7628982 Boosting an immune response in an animal; vaccine containing B. subtilis spores, in the presence or absence of an antigen
12/08/2009	US7628980 Inducing long-term protection against foreign antigens and tumor antigens by administering a type I interferon or a FMS-like tyrosine kinase 3 (Flt-3), optionally along with an attenuated virus; increasing of the number of dendritic cells
12/08/2009	CA2349506C A method for selective expression of therapeutic genes by hyperthermia
12/08/2009	CA2266584C Inhibition of bcl-2 protein expression by liposomal antisense oligodeoxynucleotides
12/03/2009	WO2009146207A1 Cripto-1 as a biomarker for chronic inflammatory disease
12/03/2009	WO2009146033A2 Compositions and methods for modulating smn activity
12/03/2009	WO2009145956A2 Uses of calpain inhibitors to inhibit inflammation
12/03/2009	WO2009144704A2 siRNA COMPOUNDS FOR INHIBITING NRF2
12/03/2009	WO2009144230A1 Protamine/rna nanoparticles for immunostimulation
12/03/2009	WO2009144132A1 Diagnostic reagent, containing bioparticles, method for production thereof and use thereof as internal standard in nucleic acid preparation and nucleic acid detection methods
12/03/2009	WO2009114878A3 Methods and compositions for genetic and retinal disease
12/03/2009	WO2009109862A3 S100a6 and/or s100a4 inhibitors for treating cancer
12/03/2009	WO2009108633A3 Sphingosine 1-phosphate antagonism
12/03/2009	WO2009098492A3 Modulation of adenoviral tropism
12/03/2009	US20090298922 Aav transduction of muscle tissue
12/03/2009	US20090298921 Methods and compositions for use in homologous recombination
12/03/2009	US20090298918 Alternative Splicing Isoform of Lox-I Protein Encoding Gene, and Uses Thereof
12/03/2009	US20090298913 Small interfering oligonucleotides comprising arabinose modified nucleotides
12/03/2009	US20090298713 Polynucleotides which are of nature b2/d+ a- and which are isolated from e. coli, and biological uses of these polynucleotides and of their polypeptides
12/03/2009	US20090298176 siRNA targeting KRAS
12/03/2009	US20090298174 Oligomeric Compounds And Compositions For Use In Modulation Of Small Non-Coding RNAs
12/03/2009	US20090298156 Thymidine Kinase Mutants and Fusion Proteins Having Thymidine Kinase and Guanylate Kinase Activities
12/03/2009	US20090298120 Method for expressing sialylated glycoproteins in mammalian cells and cells thereof
12/03/2009	US20090297515 Use of Caspase-8 Inhibitors for Modulating Hematopoiesis
12/03/2009	US20090297511 Prevention and treatment of amyloidogenic disease
12/03/2009	US20090297484 Method for curing and preventing acquired immune deficiency syndrome by altering cell-surface receptors in precursor t-helper cells and mature t-helper cells to prevent human immunodeficiency virus virions access to mature helper cells
12/03/2009	US20090297483 Adenovirus vectors specific for cells expressing androgen receptor and methods of use thereof
12/03/2009	CA2725857A1 Generation of induced pluripotent stem (ips) cells
12/02/2009	EP2128267A2 Methods of evaluating phosphatase inhibitors
12/02/2009	EP2128261A1 A recombinant adenovirus comprising recombinant khp50 gene and preparation method and uses thereof
12/02/2009	EP2128256A2 Molecular clones with mutated HIV GAG/POL, SIV GAG and SIV ENV genes
12/02/2009	EP2128248A1 Oligonucleotide compositions with enhanced efficiency
12/02/2009	EP2127681A1 Therapeutic agent for periodontal disease and alveolar bone loss due to surgery
12/02/2009	EP2127675A1 Antiviral agent
12/02/2009	EP2126078A2 Composition and methods for modulating cell proliferation and cell death
12/02/2009	EP2125032A1 Treating cancer with viral nucleic acid
12/02/2009	EP2125031A2 Lipids and lipid assemblies comprising transfection enhancer elements
12/02/2009	EP2124928A1 Use of cis-epoxyeicosatrienoic acids and inhibitors of soluble epoxide hydrolase to treat conditions mediated by pbr, cb2, and nk2 receptors
12/02/2009	EP1534670B1 Enzyme activated self-immolative n-substituted nitrogen mustard prodrugs
12/02/2009	EP1436425B1 Genes and proteins for prevention, prediction, prognosis and therapy of cardiovascular disease
12/02/2009	EP1309726B1 Rna sequence-specific mediators of rna interference
12/02/2009	CN101591666A Preparation for pCN-SSISG of dual-promoter bivalent anti-caries DNA vaccine
12/02/2009	CN101591658A ING4 and IL-24 dual gene co-expression vector and application thereof
12/02/2009	CN101591657A Thymosin beta4 gene expression inhibiting RNA and use thereof
12/02/2009	CN101591655A PKCalpha signal specifically-blocking siRNA and use thereof
12/02/2009	CN101591386A Polypeptide capable of inhibiting excitable and toxic damages and use thereof
12/02/2009	CN101591379A Constructed anti-HIV vaccine based on amino acid mutation of EIAV attenuated live vaccine
12/02/2009	CN101590243A Application of small RNAs in preparing medicaments for treating and/or preventing lymphoma
12/02/2009	CN100564527C A-type kreotoxin receptor combination region Hc, coding protein and application thereof
12/02/2009	CN100564525C Prostate gland cancer cell specific promoter and its application
12/02/2009	CN100563717C Application of LYRM1 gene in preparing medicament for promoting fat cell proliferation
12/02/2009	CN100563709C Novel targeted tissue factor antibody as anticoagulants
12/02/2009	CN100563707C Activation and inhibition of the immune system
12/01/2009	US7626074 Method of screening candidate drugs for the treatment of leukemia
12/01/2009	US7626015 Therapeutic uses of inhibitors of RTP801L
12/01/2009	US7626012 Nucleic acids encoding monoclonal antibody or an antigen-binding portion thereof that specifically binds to and activates human CD40; Gene therapy; nucleic acid coding immunoglobulins; anticancer agents
12/01/2009	US7625874 Compositions and methods for treating diseases associated with T-box and N-Myc
12/01/2009	US7625872 a branch-point nucleoside to which three core nucleic acid moieties are covalently coupled; therapy for cancer and Th2-type immune response (e.g., an allergy or allergy-induced asthma) by increasing the secretion of interferon-gamma
12/01/2009	US7625751 WNV core protein/capsid interacting protein and uses of the same
12/01/2009	US7625750 Compositions for DNA mediated gene silencing
12/01/2009	US7625558 Anticancer agents; administering nucleic acid which dimerizes with protein
11/2009
11/26/2009	WO2009143483A2 PsrP IS A PROTECTIVE ANTIGEN AGAINST PNEUMOCOCCAL INFECTION
11/26/2009	WO2009143463A2 Methods for modulating expression of creb
11/26/2009	WO2009143412A2 Polymeric systems containing intracellular releasable disulfide linker for the delivery of oligonucleotides
11/26/2009	WO2009143391A2 Methods for modulation expression of creb
11/26/2009	WO2009143390A2 Methods for modulating expression of rbp4
11/26/2009	WO2009143387A2 Modulation of smrt expression
11/26/2009	WO2009143359A2 Amido anti-viral compounds
11/26/2009	WO2009143299A1 Hepatoprotectant acetaminophen mutual prodrugs
11/26/2009	WO2009142822A2 2-f modified rna interference agents
11/26/2009	WO2009142759A1 Novel soluble cd83 polypeptides, formulations and methods of use
11/26/2009	WO2009142271A1 Cancer stem cell having high level of sld5 expression therein
11/26/2009	WO2009141335A1 An adapter molecule for the delivery of adenovirus vectors
11/26/2009	WO2009125231A3 Anti-atheroma vaccine
11/26/2009	WO2009118204A3 Medicament, compositions, and substances for treating and identifying adenocarcinoma of the lung
11/26/2009	WO2009100254A3 Protein tyrosine phosphatase inhibitors
11/26/2009	US20090292107 Composition and method to alter lean body mass and bone properties in a subject
11/26/2009	US20090292006 Compounds and methods for modulating expression of dgat2
11/26/2009	US20090292002 Nucleotide and amino acid sequences relating to respiratory diseases and obesity
11/26/2009	US20090291907 Oligomeric Compounds And Compositions For Use In Modulation Of Small Non-Coding RNAs
11/26/2009	US20090291906 Oligomeric Compounds And Compositions For Use In Modulation Of Small Non-Coding RNAs
11/26/2009	US20090291889 Diagnostic assay and method of treatment for miscarriage risk or premature birth involving macrophage inhibitory cytokine-1 (MIC-1)
11/26/2009	US20090291888 Modulators of tnf receptor associated factor (traf), their preparation and use
11/26/2009	US20090291497 efficient sequence specific gene silencing; gene expression inhibition; increases siRNA efficacy
11/26/2009	US20090291491 Retroviral vectors
11/26/2009	US20090291068 Modulation of bio-electrical rhythms via a novel engineering approach
11/26/2009	CA2725162A1 An adapter molecule for the delivery of adenovirus vectors
11/25/2009	EP2123752A2 Novel nucleic acid
11/25/2009	EP2123306A1 Use of a decoy protein that interferes with the hedgehog signalling pathway for the manufacture of a medicament for preventing, inhibiting, and/or reversing ocular diseases related with ocular neovascularization
11/25/2009	EP2123303A1 Ameliorating agent for insulin resistance
11/25/2009	EP2121914A2 Mitochondrial nucleic acid delivery systems

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