Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
06/2014
06/10/2014CA2482634C Diagnostic and therapeutic use of kremen 1 and 2, inhibitors of the canonical wnt-signal transduction
06/10/2014CA2459816C Hybrid and tandem expression of neisserial proteins
06/10/2014CA2441287C Glycosylation-resistant cyanovirins and related conjugates, compositions, nucleic acids, vectors, host cells, methods of production and methods of using nonglycosylated cyanovirins
06/10/2014CA2399280C Defects in periaxin associated with myelinopathies
06/10/2014CA2326598C Fusion proteins of mycobacterium tuberculosis antigens and their uses
06/05/2014WO2014085666A1 Methods of characterizing and treating molecular subset of muscle-invasive bladder cancer
06/05/2014WO2014085546A1 Use of ar-42 enhances e7-specific cd8+ t-cell mediated antitumor immunity in conjunction with dna vaccine
06/05/2014WO2014084430A1 Combination anti-cancer therapy
06/05/2014WO2014084246A1 Inhibitor of nucleic acid for regulating activity of rnai molecule
06/05/2014WO2014084027A1 Medical uses of cell membrane-permeable fibroblast growth factor
06/05/2014WO2014066898A9 A layer-by-layer approach to co-deliver dna and sirna via aunps: a potential platform for modifying release kinetics
06/05/2014WO2014052693A3 Veterinary composition and methods for non-surgical neutering and castration
06/05/2014WO2014041483A3 Methods for producing recombinant factor viii chains from non-filamentous fungi, their functional reconstitution and applications thereof
06/05/2014WO2014036412A3 A method for treating melanoma using a herpes simplex virus and an immune checkpoint inhibitor
06/05/2014WO2013049307A9 Enhanced immune memory development by aptamer targeted mtor inhibition of t cells
06/05/2014US20140154216 Virus strains
06/05/2014US20140154215 Herpes virus strains
06/04/2014EP2737923A2 Electro-microneedle integrated body for in-situ cutaneous gene transfer and method of manufacturing same
06/04/2014EP2736540A2 Switch costimulatory receptors
06/04/2014EP2736539A1 Recombinant virus products and methods for inhibition of expression of dux4
06/04/2014EP2736538A1 Compositions and methods of treating head and neck cancer
06/04/2014EP2736531A2 Methods and compositions for modulating the innate immune response and/or myogenesis in a mammalian subject
06/04/2014CN103834690A ER(beta)-containing recombinant virus and pharmaceutical composition containing same and application thereof
06/04/2014CN103834035A Cationic laminarin and preparation method and application thereof
06/04/2014CN103830747A Genetically engineered vaccine of epsilon toxin of clostridium perfringens and application thereof
06/04/2014CN103830746A Riemerella anatipestifer deoxyribonucleic acid (DNA) vaccine based on OmpA (octamethyl pyrophosphoramide) gene and preparation method of vaccine
06/04/2014CN103830745A Preparation and application of quantum dot-based multifunctional nano siRNA (Small Interfering Ribonucleic Acid) carrier system
06/04/2014CN103830725A Methods and compositions for the treatment of persistent infections and cancer by inhibiting the programmed cell death 1 (pd-1) pathway
06/04/2014CN103045592B Long-chain non-encoding nucleic acid segment related with duplication of flu viruses and application thereof
06/04/2014CN102994503B SiRNA (small interfering ribose nucleic acid) for inhibiting homosapiens chromosome2open reading frame 3(C2 or f3) (GCF) gene expression, carrier of SiRNA for inhibiting GCF gene expression and application
06/04/2014CN102908315B Chitosan (CS) nanoparticle delivery system of small molecular interfering ribonucleic acid and preparation method thereof
06/04/2014CN102776155B Chinese isolated strain of bovine enterovirus, and construction and application of infectious cDNA clone thereof
06/04/2014CN102727909B Novel method for inhibiting primary liver cancer growth and metastasis
06/04/2014CN102552910B Application of extracellular matrix protein 1 and regulator thereof in preparing medicament for diagnosing or treating allergic diseases
06/04/2014CN102373218B Nucleic acid sequence coding Momordica charantia polypeptide P
06/04/2014CN102191233B Novel 10-23 deoxyribozyme analogue and application thereof
06/04/2014CN101851618B Modified small interfering RNA and preparation method thereof
06/03/2014US8742092 RNA sequence-specific mediators of RNA interference
06/03/2014US8742091 Method of promoting nucleic acid transfer
06/03/2014US8742090 Property effecting and/or property exhibiting compositions for therapeutic and diagnostic uses
06/03/2014US8741870 Axl receptor tyrosine kinase aptamer inhibitor for use in therapy
06/03/2014US8741868 Pharmaceutical composition including an HIF-2 alpha inhibitor as an active ingredient for preventing or treating arthritis
06/03/2014US8741866 Compositions and methods for inhibiting expression of transthyretin
06/03/2014US8741862 PHD2 inhibition for blood vessel normalization, and uses thereof
06/03/2014US8741860 Modulation of T cell signaling threshold and T cell sensitivity to antigens
06/03/2014US8741576 Heteroclitic analogs and related methods
06/03/2014US8741346 Method for the preparation of molecular complexes
06/03/2014US8741340 Cell lines and their use in encapsulated cell biodelivery
06/03/2014US8741279 Gene delivery system and methods of use
06/03/2014CA2541240C Method for the production of a cell and/or tissue and/or disease phase specific medicament
06/03/2014CA2529142C Rna interferases and methods of use thereof
06/03/2014CA2497913C Use of chimeric nucleases to stimulate gene targeting
06/03/2014CA2443995C Endothelial cell expression patterns
06/03/2014CA2412764C Stimulation of cellular regeneration and differentiation in the inner ear
06/03/2014CA2406171C Reversible immortalization of cells
06/03/2014CA2370081C Lpl variant therapeutics
05/2014
05/30/2014WO2014082083A1 Biomarker compositions and methods
05/30/2014WO2014080997A1 Anti-midkine aptamer and applications thereof
05/30/2014WO2014080703A1 Modified galectin-9 protein
05/30/2014WO2014079158A1 Active-targeting, small interference ribonucleic acid delivery vector and preparation method thereof
05/30/2014WO2014057432A9 Multicomponent lipid nanoparticles and processes for the preparation thereof
05/30/2014WO2014055442A3 Compositions and methods for targeting stromal cells for the treatment of cancer
05/30/2014WO2014036468A3 Aav mediated aquaporin gene transer to treat sjogren's syndrome
05/30/2014WO2014022475A8 Compositions and methods for conformationally stabilizing primate immunodeficiency virus envelope glycoprotein trimers
05/29/2014US20140148880 Upconversion of Light for Use in Optogenetic Methods
05/29/2014US20140148582 Nucleic acids encoding biologically active polypeptides derived from a novel early stage pregnancy factor designated maternin (ma)
05/29/2014US20140147493 Pcr-based gene delivery carrier and method for preparing the same
05/28/2014EP2735613A1 TECHNIQUE FOR CLEAVING OUT PART OF poly(A) CHAIN AND/OR 3'-TERMINAL SEQUENCE OF mRNA TO INHIBIT TRANSLATION REACTION
05/28/2014EP2735314A1 Improved sugar-coated liposome composition
05/28/2014EP2734240A2 Protection of cells from alu-rna-induced degenereation and inhibitors for protecting cells
05/28/2014CN103826691A 用于原位皮肤基因转移的电子微针集成体及其制备方法 Electronic integration of the microneedle and its preparation method for gene transfer in situ skin
05/28/2014CN103826662A 评估急性肾损伤等级的方法和试剂 Assessment of acute kidney injury rating methods and reagents
05/28/2014CN103820562A 用于乳腺癌的诊断、预后和治疗的基于MicroRNA的方法和组合物 Methods and compositions for the diagnosis, prognosis and treatment of breast cancer based MicroRNA
05/28/2014CN103820528A Reelin及其拮抗剂在骨髓瘤患者分期及预后中的新应用 Reelin its antagonist new applications in staging and prognosis of patients with myeloma
05/28/2014CN103820498A 一种基于Notch信号胞内域NICD1构建的慢病毒表达载体及其应用 Based on the intracellular domain of Notch signaling NICD1 construct lentiviral expression vector and its application
05/28/2014CN103820472A 用于食管癌防治的hpv16,18l1重组dna疫苗 Hpv16,18l1 recombinant dna vaccine for the prevention of esophageal cancer
05/28/2014CN103820450A 因子11表达的调节 Regulate the expression of factor 11
05/28/2014CN103820438A 改善间充质干细胞成骨能力的rna分子及其作用靶点和应用 Improve inter-derived mesenchymal stem cells into bone ability rna molecules and their targets and applications
05/28/2014CN103816549A 茶树来源的3种microRNA及其应用 Sources of three kinds of tea microRNA and its application
05/28/2014CN103816541A ADP受体p2y12在血管生成中的应用 ADP receptor p2y12 application in angiogenesis
05/28/2014CN103816540A 降低β-抑制蛋白1与APH-1蛋白的结合的物质在制备防治神经退行性疾病药物中的应用 Reducing β- inhibit the binding protein 1 and the APH-1 protein substance prepared in the prevention and treatment of neurodegenerative diseases, drugs Application
05/28/2014CN103816122A 一种靶向sr-bi受体的基因与化疗药物共传输抗肿瘤纳米粒的制备及应用 A targeted gene with chemotherapy drugs sr-bi receptor co-transmission antitumor preparation and application of nanoparticles
05/28/2014CN102772796B O型口蹄疫病毒中含缅甸亚型的3个亚型基因工程多肽疫苗及其制备和用途 O-type FMD virus subtypes containing three subtypes of Myanmar genetically engineered peptide vaccine and its preparation and use
05/28/2014CN102504280B 一种利用改性超支化高分子制备类生物膜囊泡结构的方法 A use of modified hyperbranched polymer vesicles prepared in the class structure of the biofilm methods
05/27/2014US8735567 Multi-targeted RNAi therapeutics for scarless wound healing of skin
05/27/2014US8735566 Bacterially derived intact minicells that encompass plasmid free functional nucleic acid for in vivo delivery to mammalian cells
05/27/2014US8735371 Compositions and methods for altering RNAi
05/27/2014US8735370 Modulation of factor 11 expression
05/27/2014US8735369 Compositions and methods for inhibiting expression of a gene from the Ebola virus
05/27/2014US8735364 Antisense modulation of apolipoprotein B expression
05/27/2014US8735361 C1ORF59 peptides and vaccines including the same
05/27/2014US8735340 Conjugates that contain the homeodomain of antennapedia
05/27/2014US8735145 Property effecting and/or property exhibiting compositions for therapeutic and diagnostic uses
05/27/2014US8735066 Tumor suppressor designated TS10Q23.3
05/27/2014US8734812 Neisserial antigenic peptides
05/27/2014US8734781 Method of preventing early Lawsonia intracellularis infections
05/27/2014US8734779 5-fluorouracil-resistant bacteria and method for production thereof
05/27/2014CA2597698C Mycobacterial mutants affecting host apoptosis
05/27/2014CA2551696C Immunopotentiator and method of enhancing immunoactivity using the same
05/27/2014CA2421063C Methods for stable transduction of cells with viral vectors
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