Patents
Sitemap › A61 - Medical or veterinary science; Hygiene › A61K - Preparations for medical, dental, or toilet purposes › A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
11/2010
11/23/2010US7838561 administering to mammal or higher vertebrate an effective amount of a pharmaceutical composition comprising N-[4-hydroxyphenyl]retinamide
11/23/2010US7838555 Useful in the treatment and prophylaxis of inflammatory conditions or in the amelioration of symptoms resulting from or facilitated by an inflammatory condition in a mammalian animal including human and primate, non-mammalian animal and
11/23/2010US7838507 connective tissue growth factor (CTGF) expression inhibition; treating glaucoma, macular degeneration, diabetic retinopathy, choroidal neovascularization, proliferative vitreoretinopathy and wound healing
11/23/2010US7838505 using hybrid Hepatocyte Growth Factor (HGF) construct for prevention and treatment of ischemic and liver disorders
11/23/2010US7838504 Reducing flavivirus or Hepatitis virus replication in vitro or vivo by inhibiting activity of a microRNA; administering an antisense oligonucleotide complementary to microR-122
11/23/2010US7838501 chimera; nuclear factor kappa beta; vectors, host cell; gene therapy; pharmacokinetics
11/23/2010US7838294 Inhibitors of the JNK signal transduction pathway and methods of use
11/23/2010US7838291 they produce material which inhibits the proliferation of other, non-entrapped cells, including stem cells and neoplastic and/or hyperproliferative, but otherwise normal cells; cancer; entrapment process can serve as a long-term storage device for maintaining the undifferentiated state of the cells
11/23/2010US7838290 Hematopoietic stem cells and methods of treatment of neovascular eye diseases therewith
11/23/2010US7838289 Assay utilizing multipotent adult stem cells
11/23/2010US7838277 Viral vector comprising adenovirus capsid gene sequences for use as tool for delivery and expression of heterologous gene sequences in cells
11/23/2010US7838266 A purified pro-cytolytic peptide; used to treat localized and metastatic prostate cancer; administered intratumorally and/or intraprostatically
11/23/2010US7838247 determination of the Alzheimer Related Membrane Protein (ARMP) gene on chromosome 14 and a related gene, E5-1, on chromosome 1; diagnosing Alzheimer's disease
11/23/2010US7838041 autologously transplanting hematopoietic progenitor cell population which has been treated with antibody (monoclonal, chimeric, or humanized; not conjugated to toxin or cytolytic agent); radiotherapy
11/23/2010US7838015 Adjuvanted meningococcus compositions
11/23/2010US7837991 detecting an inhibitor of p53 protein degradation comprising providing a cell extract containing one or more p53 protein proteases; capable of modulating calpaine activity
11/23/2010CA2444529C Micellar drug delivery systems for hydrophobic drugs
11/23/2010CA2354148C Aerosol formulations for buccal and pulmonary application
11/23/2010CA2315271C Platelet derived growth factor (pdgf) nucleic acid ligand complexes
11/23/2010CA2295189C Type-1 ribosome-inactivating protein
11/23/2010CA2263823C Mammalian artificial chromosomes
11/23/2010CA2252565C Dna vaccine formulations
11/23/2010CA2232738C Strategy for suppressing the expression of an endogenous gene
11/23/2010CA2222140C Packaging systems for human recombinant adenovirus to be used in gene therapy
11/23/2010CA2209301C Redirection of cellular immunity by protein-tyrosine kinase chimeras
11/23/2010CA2169292C Improved compositions and methods for the delivery of biologically active molecules using genetically altered cells contained in biocompatible immunoisolatory capsules
11/23/2010CA2158791C Dna sequences encoding the machado-joseph disease gene and uses thereof
11/18/2010WO2010132861A2 Diagnostic and treatment for chronic and acute phase myeloid leukemia
11/18/2010WO2010132845A1 Organisms for the production of cyclohexanone
11/18/2010WO2010132047A1 Guanosine/gmp gels and uses thereof
11/18/2010WO2010131916A2 Sirna conjugate and preparation method thereof
11/18/2010WO2010131777A1 Fine particles of crystalline polyol and method of preparing same
11/18/2010WO2010131704A1 Test agent for visceral obesity and use thereof
11/18/2010WO2010130844A1 Aslv vector system
11/18/2010WO2010130418A2 Treatment of eye diseases using encapsulated cells encoding and secreting a neuroprotective factor and/or an anti-angiogenic factor
11/18/2010WO2010130073A1 Itgb4bp and derivative thereof used in treatment and/or prevention of hyperplastic scar and fibrosis
11/18/2010WO2010034670A3 Host cell kinases as targets for antiviral therapies against hcv infection
11/18/2010WO2009140421A8 Polymeric carrier
11/18/2010US20100292456 Rna interference mediating small rna molecules
11/18/2010US20100292455 MODIFIED iRNA AGENTS
11/18/2010US20100292308 Microrna molecules
11/18/2010US20100292142 Novel neurotrophic factors
11/18/2010US20100291681 Methods and compositions for selecting siRNA of improved functionality
11/18/2010US20100291171 Hyaluronic acid derivatives obtained via "click chemistry" crosslinking
11/18/2010US20100291139 Recombinant mva virus and the use thereof
11/18/2010US20100291127 Tumor associated antigen peptides and use of same as anti-tumor vaccines
11/18/2010US20100291126 Protein showing enhanced expression in cancer cells
11/18/2010US20100291121 Tumour-Specific Animal Proteins
11/18/2010DE102009021592A1 ASLV-Vektorsystem ASLV-vector system
11/18/2010CA2766676A1 Aslv vector system
11/18/2010CA2761749A1 Sirna conjugate and preparation method thereof
11/17/2010EP2251424A1 Antigenic neisserial peptides
11/17/2010EP2251350A2 RORalpha promoting the induction of Bmal1
11/17/2010EP2251040A1 Use of a melanoma differentiation associated gene (mda 7) for reversing a cancerous phenotype
11/17/2010EP2251039A2 Oligo double-stranded rna inhibiting the expression of bcl-2 and pharmaceutical composition containing the same
11/17/2010EP2251028A1 Treatment of eye diseases using encapsulated cells encoding and secreting an anti-angiogenic factor and/or a neuroprotective factor
11/17/2010EP2250282A2 Methods of diagnosing and treating parp-mediated diseases
11/17/2010EP2250267A1 Cationic sirnas, synthesis and use for interfering rna
11/17/2010EP2249874A1 Methods and means for treating dna repeat instability associated genetic disorders
11/17/2010EP2249856A2 Peptides that target dorsal root ganglion neurons
11/17/2010EP1760153B1 Adenovirus/alphavirus hybrid vector for the effective administration and expression of therapeutic genes in tumour cells
11/17/2010EP1624899B1 INCREASED TRANSDUCTION USING ABC TRANSPORTER SUBSTRATES that are INHIBITORS
11/17/2010EP1276852B1 Viruses comprising mutated ion channel protein
11/17/2010EP1204682B1 Compositions and methods for the treatment of tumors
11/17/2010EP1181358B1 Methods and materials for generating sh3 domains with tailored binding properties
11/17/2010EP0862419B2 Microencapsulated dna for vaccination and gene therapy
11/17/2010CN101889086A Splice switching oligomers for tnf superfamily receptors and their use in treatment of disease
11/17/2010CN101889007A Method for amplifying hematopoietic stem cells using heterocyclic compound
11/17/2010CN101886115A Application of three microRNAs in diagnosis and treatment of human acute myeloid leukemia
11/17/2010CN101886090A Plasmids coding for p185neu protein sequence variants and therapeutic uses thereof
11/17/2010CN101886084A Codon-optimized H3HA/XJ3-07 gene and nucleic acid vaccine thereof
11/17/2010CN101886076A Oligonucleotide for inhibiting blood-mediated inflammatory reaction in pancreatic islet transplantation
11/17/2010CN101885766A Novel neurotrophic factor, preparation thereof and application thereof
11/17/2010CN101885760A HIV-1gp120 gene consensus sequence optimized by codon and gp120 nucleic acid vaccine
11/17/2010CN101884794A Application of S100A16 gene in preparing medicaments for treating insulin resistance
11/17/2010CN101884793A Immune enhanced gene vaccine of hepatitis B virus core antigen and preparation method thereof
11/17/2010CN101884792A Immune enhanced gene vaccine of hepatitis B virus surface antigen and preparation method thereof
11/17/2010CN101884784A Bv8 nucleic acids and polypeptides with mitogenic activity
11/17/2010CN101884780A Use of hepcidin as a regulator of iron homeostasis
11/17/2010CN101497882B Anti- mycobacterium tuberculosis infection small molecule nucleotide DNA aptamer and preparation thereof
11/17/2010CN101402942B PolyLyse-HSP70 fusion protein film modified intestinal cancer cytoma vaccine and method of producing the same
11/16/2010US7834171 Modified polynucleotides for reducing off-target effects in RNA interference
11/16/2010US7834170 Short interference RNA duplexes, when introduced into mammalian cells in culture, perform sequence-specific inhibition of target mRNA without inducing an interferon response; specific gene silencing
11/16/2010US7834143 Cell surface receptor for use as tool in identifying modulators of vascular pressure
11/16/2010US7833989 siRNA targeting connective tissue growth factor (CTGF)
11/16/2010US7833785 Method for chemical dissociation of cells from physical surfaces
11/16/2010US7833783 Postweaning multisystemic wasting syndrome and porcine circovirus from pigs
11/16/2010US7833722 Ligands for G protein-coupled receptor protein and use thereof
11/16/2010US7833535 Neuropeptide Y, kyotorphin, calcitonin-gene related peptides bind receptors; Clostridial toxin HN domain translocates toxin light chain across endosome membrane;Clostridial toxin light chain cleaves a neurosecretory protein; HC domain modified to reduce binding to receptors at neuromuscular junction
11/16/2010US7833521 Admnistering a fusion protein of interferon and albumin or an albumin variant, having a higher plasma stability than unfused interferon; albumin or variant is located either at the N-terminus or C-terminus of the fusion protein, fusion protein retains the therapeutic activity of unfused interferon
11/16/2010CA2523216C Recombinant alphavirus vectors
11/16/2010CA2428739C Complementing cell lines
11/16/2010CA2422622C Novel baff-r nucleic acids and polypeptides
11/16/2010CA2337361C Targeted site specific drug delivery compositions and method of use
11/16/2010CA2283462C Vectors having enhanced expression and methods of making and uses thereof
11/16/2010CA2278151C Heregulin variants
11/16/2010CA2261334C Bovine polynucleotide vaccine for the intradermal route
11/11/2010WO2010129861A2 Treatment of dystrophin family related diseases by inhibition of natural antisense transcript to dmd family
11/11/2010WO2010129799A2 Treatment of lipid transport and metabolism gene related diseases by inhibition of natural antisense transcript to a lipid transport and metabolism gene
11/11/2010WO2010129708A2 Methods and compositions related to the regulation of goblet cell differentiation, mucus production and mucus secretion
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