Patents for C40B 30 - Methods of screening libraries (11,320)
12/1999
12/16/1999CA2321190A1 Novel therapeutic agents that modulate enzymatic processes
12/16/1999CA2321166A1 Multibinding inhibitors of topoisomerase
12/16/1999CA2321162A1 Novel antibacterial compounds
12/16/1999CA2320290A1 Multibinding inhibitors of cyclooxygenase-2
12/16/1999CA2320241A1 Multivalent macrolide antibiotics
12/16/1999CA2319761A1 Multibinding inhibitors of hmg-coa reductase
12/16/1999CA2319495A1 Multibinding inhibitors of microsomal triglyceride transferase protein
12/16/1999CA2319477A1 Inhibitors of h+k+-atpase
12/16/1999CA2319474A1 Inhibitors of nitric oxide synthase
12/16/1999CA2319120A1 Phosphodiesterase-v modulator drugs and their uses
12/16/1999CA2318547A1 Combinatorial synthesis of multibinding libraries
12/16/1999CA2316999A1 Inhibitors of hiv reverse transcriptase
11/1999
11/30/1999US5994083 Collect serum samples from infected pateints with antibodies and a healthy individual, identify antibodies which bind antigens specific to the disease from phage library; select phages that display antigen recognized by antibody; vaccines
11/25/1999WO1999060007A2 Libraries of oligomers labelled with different tags
11/25/1999WO1999059716A2 Combinational method for microgram-scale production and characterization of crystalline and amorphous libraries of materials
11/25/1999CA2333178A1 Combinational method for microgram-scale production and characterization of crystalline and amorphous libraries of materials
11/25/1999CA2332862A1 Libraries of oligomers labelled with different tags
11/18/1999WO1999058947A2 Modulation of molecular interaction sites on rna and other biomolecules
11/18/1999WO1999058476A2 Method and device for nonsynthetic deconvolution
11/18/1999WO1999058474A1 Generation of combinatorial libraries of compounds corresponding to virtual libraries of compounds
11/18/1999WO1999051546A9 Parallel combinatorial approach to the discovery and optimization of catalysts and uses thereof
11/18/1999WO1999049314A9 Pharmacophore recombination for the identification of small molecule drug lead compounds
11/18/1999DE19822077A1 Preparation of library of spatially separted solids by wet-chemical methods on a removable reaction plate, used e.g. to screen for new catalysts or materials
11/16/1999US5985356 Screening
11/11/1999WO1999056788A1 Selection of targeted contrast agents from a combinatorial library
11/11/1999WO1999041007A3 Method and apparatus for chemical and biochemical reactions using photo-generated reagents
11/10/1999EP0954601A1 A method for identifying cytotoxic t-cell epitopes
11/04/1999WO1999056129A1 Methods of selecting internalizing antibodies
11/03/1999EP0953835A1 Apparatus for detection of a fluorescence pattern corresponding to ligand binding on a substrate
10/1999
10/21/1999WO1999009416A3 Method of drug selection
10/21/1999CA2325013A1 Identification of genetic targets for modulation by oligonucleotides and generation of oligonucleotides for gene modulation
10/14/1999WO1999051773A1 Addressable protein arrays
10/14/1999WO1999051546A1 Parallel combinatorial approach to the discovery and optimization of catalysts and uses thereof
10/14/1999WO1999038013A3 Method for simultaneous identification of proteins and bonding partners
10/14/1999CA2326387A1 Parallel combinatorial approach to the discovery and optimization of catalysts and uses thereof
10/14/1999CA2323638A1 Addressable protein arrays
10/07/1999WO1999050669A1 Methods for screening compound libraries
10/07/1999WO1999050668A1 Apparatus for screening compound libraries
10/07/1999WO1999050667A1 Electrospray device for mass spectrometer
10/07/1999WO1999050664A1 Compositions and methods for detecting ligand-dependent nuclear receptor and coactivator interactions
10/07/1999WO1999049898A1 Progression elevated gene-3 and uses thereof
10/07/1999CA2735260A1 Methods for the diagnosis and treatment of lung cancer by detection of proto-oncogene overexpression
10/07/1999CA2326573A1 Compositions and methods for detecting ligand-dependent nuclear receptor and coactivator interactions
10/07/1999CA2316817A1 Electrospray device for mass spectrometer
10/06/1999EP0946878A1 Optimization of gene delivery and gene delivery systems
09/1999
09/30/1999WO1999049315A1 Small molecule library screening using facs
09/30/1999WO1999049314A1 Pharmacophore recombination for the identification of small molecule drug lead compounds
09/29/1999EP0944737A1 Representations of bimolecular interactions
09/28/1999US5959297 Mass spectrometers and methods for rapid screening of libraries of different materials
09/28/1999US5958273 Induction heated reactor apparatus
09/16/1999DE19809477A1 Catalyst test unit
09/01/1999EP0938742A1 Method and device for revealing a catalytic activity by solid materials
08/1999
08/31/1999US5945679 Apparatus for scanning a chemical array
08/26/1999CA2743347A1 Methods of screening agents for activity using teleosts
08/25/1999EP0781436A4 System and method of automatically generating chemical compounds with desired properties
08/25/1999CN1226966A Catalyst testing process and system
08/19/1999WO1999041407A1 Method for developing a pharmaceutical active ingredient
08/19/1999WO1999041011A1 Metallic reactor tube with catalytic coating
08/19/1999WO1999041007A2 Method and apparatus for chemical and biochemical reactions using photo-generated reagents
08/19/1999WO1999041005A1 Method for the combinatorial production and testing of heterogeneous catalysts
08/19/1999DE19806848A1 Array of heterogeneous catalysts, or precursors, each arranged in separate channel, used to screen for activity, selectivity or long-term stability
08/19/1999DE19805719A1 Array of heterogeneous catalysts, or precursors, each arranged in separate channel, used to screen for activity, selectivity or long-term stability
08/12/1999WO1999024050A9 High throughput method for functionally classifying proteins identified using a genomics approach
08/12/1999WO1999009417A3 Method of drug selection
08/12/1999DE19805334A1 Verfahren zur Entwicklung eines pharmazeutischen Wirkstoffes A method of developing a pharmaceutical active ingredient
08/11/1999EP0934526A1 Methods and means for selecting peptides and proteins having specific affinity for a target
08/11/1999EP0934515A1 Infrared spectroscopy and imaging of libraries
08/05/1999WO1999039210A1 High density arrays for proteome analysis and methods and compositions therefor
08/05/1999WO1999021015A3 Affinity ligands, their production and use
08/05/1999CA2319828A1 High density arrays for proteome analysis and methods and compositions therefor
07/1999
07/29/1999WO1999038013A2 Method for simultaneous identification of proteins and bonding partners
07/29/1999WO1999038008A1 Methods and compositions for the identification of growth factor mimetics, growth factors and inhibitors
07/29/1999WO1999023587A3 Method of virtual retrieval of analogs of lead compounds
07/29/1999CA2707152A1 Biomarkers and targets for diagnosis, prognosis and management of prostate disease
07/15/1999WO1999035109A1 Method for producing mass-coded combinatorial libraries
07/08/1999WO1999034206A1 Method for combinatorial material development using differential thermal images
07/07/1999CA2219958A1 The g-protein .beta.subunit interaction domain of ste20p/pak family of protein kinases and uses thereof in bioassays
07/01/1999WO1999006587A3 Novel method and phage for the identification of nucleic acid sequences encoding members of a multimeric (poly)peptide complex
06/1999
06/24/1999WO1999031509A1 Improved method for the identification and characterization of interacting molecules using automation
06/24/1999WO1999031265A1 Compounds and methods for the inhibition of protein-protein interactions
06/24/1999CA2312913A1 Compounds and methods for the inhibition of protein-protein interactions
06/24/1999CA2311896A1 Improved method for the identification and characterization of interacting molecules using automation
06/17/1999WO1999030151A1 Method and cells to screen combinatorial libraries
06/17/1999CA2310381A1 Method and cells to screen combinatorial libraries
06/16/1999EP0922957A1 Method to determine biomeolecular interaction
06/10/1999WO1999028745A1 Identification and characterization of interacting molecules by automated interaction mating
06/10/1999WO1999028744A1 Identification and characterization of interacting molecules
06/10/1999CA2311927A1 Identification and characterization of interacting molecules
06/10/1999CA2311705A1 Identification and characterization of interacting molecules by automated interaction mating
06/09/1999CN1219240A Purification of tissue plasminogen activator
06/03/1999WO1999026901A1 Method of designing chemical substances
05/1999
05/27/1999WO1999009417A9 Method of drug selection
05/26/1999EP0918296A1 Method of virtual retrieval of analogs of lead compounds by constituting potential libraries
05/26/1999EP0917494A1 Systems and methods for the combinatorial synthesis of novel materials
05/20/1999WO1999024050A1 High throughput method for functionally classifying proteins identified using a genomics approach
05/20/1999CA2628053A1 Affinity markers for human serum albumin
05/19/1999EP0575410B1 Selection of specific proteins by a biological method
05/14/1999WO1999023587A2 Method of virtual retrieval of analogs of lead compounds
05/14/1999CA2306822A1 Method of virtual retrieval of analogs of lead compounds
05/12/1999EP0914608A1 Microplate thermal shift assay and apparatus for ligand development and multi-variable protein chemistry optimization