Patents for C12Q 1 - Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions (300,231)
11/2001
11/22/2001US20010044531 For probes, comprising a heterocycle condensed with a cyclic group such as ribofuranose derivative; biotin and 5-carboxyfluorescein derivatives
11/22/2001US20010044523 Ligand (ACT-4-L) to a receptor on the surface of activated CD4+ T-cells
11/22/2001US20010044414 Inhibiting metastasis in a mammal by administering an agent which alters the actin-based cytoskeleton of tumor cells; inhibiting specified genes involved in metastasis, RhoC for example; predicting likelihood of metastatic condition
11/22/2001US20010044177 Manufacture of a microsensor device and a method for evaluating the function of a liquid by the use thereof
11/22/2001US20010044151 Ligands for modulating the expression of exogenous genes via an ecdysone receptor complex
11/22/2001US20010044145 Reduction of genetic expression of RNA target via antisense oligonucleotide
11/22/2001US20010044144 Production of adenine nucleotide translocator (ANT), novel ANT ligands and screening assays therefor
11/22/2001US20010044137 Sequence determination using polymerase chain reaction; Vaccinia virus linker
11/22/2001US20010044134 Cytokines; transcription factors; for detection of cancer, genetic abnormalities
11/22/2001US20010044132 Spotting target nucleic acid sequence on substrate, hybridizing with sample containing mixture of differently labeled nucleic acids, determining log ratio of signals, normalizing, then calculating anti-log
11/22/2001US20010044128 Stabilized coenzyme solutions and their use for determining dehydrogenases or substrates thereof
11/22/2001US20010044122 Enriched central nervous system stem cell and progenitor cell populations, and methods for identifying, isolating and enriching for such populations
11/22/2001US20010044117 Fluorescence-based high throughput screening assays for protein kinases and phosphatases
11/22/2001US20010044116 Particulate support bound to at least 2 signal-generating moieties each of which generates, in situ, a signal different from that generated by the other(s); each signal can be varied over a series of gradations
11/22/2001US20010044115 Biomonomer containing fluid is deposited on a region of a substrate that contains a solid activator and repeating to form the biopolymer; apparatus having the deposition system and processor; computer program
11/22/2001US20010044114 Chemically assembled nano-scale circuit elements
11/22/2001US20010044113 Invasive detection of colonic biomarkers
11/22/2001US20010044109 Method of determining the sequence of nucleic acids employing solid-phase particles carrying transponders
11/22/2001US20010044107 The use of recombinase such as E. coli recA protein to mediate the detection of target sequences on gene chips.
11/22/2001US20010044106 Method and apparatus for solid state molecular analysis
11/22/2001US20010044105 Forming RNA fragemnts, fixing a first ligand to a terminal phosphate that has been released during fragmentation, and binding labeling agents to the first ligand
11/22/2001US20010044104 The gene expression differences thus identified can be used to diagnose disease, identify physiological state, design drugs, and monitor therapies.
11/22/2001US20010044103 Methods for the diagnosis and prognosis of acute leukemias
11/22/2001US20010044102 Assays and reagents for identifying modulators of cdc25-mediated mitotic activation
11/22/2001US20010044101 Identifying drug resistant mutant proteins that have been expressed by a library of nucleotide sequences; comparing the relative ultimate clincal efficacies of different drugs targeted against a single protein
11/22/2001US20010044100 Messenger RNA is used as a target (marker) which exists mainly on float in the cytoplasm and is a transcriptional product of a gene instead of using the translation product.
11/22/2001US20010043931 (HRSV); Drug screening for a drug that inhibits the virus' membrane fusion machinery, such as drugs that bind the N-helix coiled-coil of HRSV and thus inhibit infection; vaccines, antibodies
11/22/2001US20010043922 Recombinants of the multiply deficient adenoviral vectors; a therapeutic method and their use particularly relating to gene therapy and vaccination
11/22/2001US20010042683 Electrochemical-sensor design
11/22/2001DE10123183A1 Primer for strand-displacement primer extension, useful e.g. for detecting pathogenic bacteria, comprises two target-specific regions, flanking a non-binding region
11/22/2001DE10024830A1 Identifying heterologous oligonucleotides, useful as primers and probes for detecting target nucleic acids, particularly viruses and their variants and mutants
11/22/2001DE10023130A1 Nucleotide chip for specific detection of the hyphal, virulent, form of Candida albicans, comprises a solid support carrying a nucleotide sequence for identifying and transcribing genes that encode hyphae-specific proteins
11/22/2001DE10022750A1 Preparing surface with immobilized recognition elements, useful e.g. in biosensors, by electrodeposition of resin from emulsion containing active substances
11/22/2001DE10022304A1 Kit for detecting microorganisms, e.g. in clinical or environmental samples, by hybridization, with all or most steps performed in a single vessel, comprises nucleic acid probes
11/22/2001DE10021019A1 Sensitive enzymatic determination of N-acetyl-neuraminic acid, e.g. for use in diagnosis, involving reacting sample with excess phosphoenol pyruvate in presence of cleaving and synthesizing enzymes
11/22/2001CA2410181A1 Novel motor proteins and methods for their use
11/22/2001CA2409948A1 Methods for detecting for the presence of tumor cells and for screening for anti-tumor agents
11/22/2001CA2409752A1 Single copy genomic hybridization probes and method of generating same
11/22/2001CA2409705A1 Gene responsible for stargardt-like dominant macular dystrophy
11/22/2001CA2409414A1 Ssa-56kda polypeptide and its fragments and polynucleotides encoding said polypeptides and therapeutic uses
11/22/2001CA2409154A1 Compositions, kits, and methods for identification and modulation of t helper-1 and t helper-2 cells and diseases associated therewith
11/22/2001CA2409148A1 Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
11/22/2001CA2409108A1 Isolated human g-protein coupled receptors, nucleic acid molecules encoding human gpcr proteins, and uses thereof
11/22/2001CA2409077A1 Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
11/22/2001CA2409068A1 Novel dual oxidases as mitogenic and endocrine regulators
11/22/2001CA2408891A1 Separation device
11/22/2001CA2408830A1 Treatment of human papillomavirus (hpv)-infected cells
11/22/2001CA2408756A1 Immune potentiating compositions
11/22/2001CA2408701A1 Compositions and methods for tissue dedifferentiation and regeneration
11/22/2001CA2408691A1 Compositions and methods for achieving immune suppression
11/22/2001CA2408513A1 Immunomodulatory human mhc class ii antigen-binding polypeptides
11/22/2001CA2408374A1 Mutation in the .beta.2 nicotinic acetylcholine receptor subunit associated with nocturnal frontal lobe epilepsy
11/22/2001CA2408373A1 Therapeutic approaches to diseases by suppression of the nurr subfamily of nuclear transcription factors
11/22/2001CA2408360A1 Human polypeptides causing or leading to the killing of cells including lymphoid tumor cells
11/22/2001CA2408246A1 Cell line for the expression of an .alpha.2.delta.2 calcium channel subunit
11/22/2001CA2408134A1 G-protein coupled receptors
11/22/2001CA2407141A1 Detection of nucleic acid hybridization by fluorescence polarization
11/22/2001CA2375082A1 Sequence based screening
11/21/2001EP1156332A2 Assay methods for cyclin dependent kinases
11/21/2001EP1156329A2 Molecular modification assays
11/21/2001EP1156325A1 Biosensor
11/21/2001EP1156123A1 Method for detecting a variation of GH1 as indicator of growth hormone dysfunction
11/21/2001EP1156122A2 A fluorescence polarization assay method
11/21/2001EP1156121A2 Urinary trypsin inhibitor assay containing a chelating agent
11/21/2001EP1156117A2 Methods for isolating modulators of carotenoid biosynthesis enzymes
11/21/2001EP1156115A1 Corynebacterium glutamicum strain with enhanced secretion activity
11/21/2001EP1156107A1 Method for analyzing gene expression frequency
11/21/2001EP1155379A1 Determining protein function and interaction from genome analysis
11/21/2001EP1155361A2 Methods to reduce variance in treatment studies using genotyping
11/21/2001EP1155328A1 Test kit for analysing factor viii-splitting protease
11/21/2001EP1155326A1 Protein assay
11/21/2001EP1155325A1 Method for diagnosing and distinguishing stroke
11/21/2001EP1155321A1 Compositions and methods for monitoring the modification of engineered binding partners
11/21/2001EP1155320A1 Isolating a cytoplasmic fraction without impairing the viability of oocytes and embryonic cells
11/21/2001EP1155310A1 Disposable test strips with integrated reagent/blood separation layer
11/21/2001EP1155304A2 A system for cell-based screening
11/21/2001EP1155153A1 Method and kit for early cancer prediction
11/21/2001EP1155152A1 Methods and kits for screening nucleic acid duplex stability
11/21/2001EP1155151A1 Methods for determining the presence of nucleic acid target sequences and applications thereof
11/21/2001EP1155150A1 Multiplex method for nucleic acid detection
11/21/2001EP1155149A1 Detection of nucleic acid hybrids
11/21/2001EP1155148A1 Detection and quantification of micro-organisms using amplification and restriction enzyme analysis
11/21/2001EP1155147A1 Methods for preserving dna integrity
11/21/2001EP1155146A2 Diagnostic and screening method for male infertility
11/21/2001EP1155145A1 New assay
11/21/2001EP1155143A1 Determination of nuclease activity
11/21/2001EP1155142A1 Sterilization indicator for liquid peracetic acid procedures
11/21/2001EP1155141A2 Detection of pathogens, especially spirochetes, from body fluids
11/21/2001EP1155140A1 Methods for making morpholino-nucleotides, and their use for analysing and marking nucleic acid sequences
11/21/2001EP1155132A1 Production of heterologous polypeptides from freshwater caulobacter
11/21/2001EP1155131A2 Compositions and methods for non-targeted activation of endogenous genes
11/21/2001EP1155130A2 Glucose dehydrogenase fusion proteins and their utilization in expression systems
11/21/2001EP1155125A1 Genetically filtered shotgun sequencing of complex eukaryotic genomes
11/21/2001EP1155119A1 Bhv-1 gene-deleted virus vaccine
11/21/2001EP1155114A1 Avian pluripotent embryonic germ cell line
11/21/2001EP1155028A1 Pigment protein from coral tissue
11/21/2001EP1155026A2 Method for isolating nucleic acids
11/21/2001EP1154998A1 Inhibitors of cellular niacinamide mononucleotide formation and their use in cancer therapy
11/21/2001EP1154991A1 Salicylamide-lanthanide complexes for use as luminescent markers
11/21/2001EP1154990A1 Phthalamide-lanthanide complexes for use as luminescent markers