Patents for C12Q 1 - Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions (300,231)
12/2004
12/23/2004WO2004065550A3 Nucleic acid amplification using non-standard bases
12/23/2004WO2004059291A3 Fret-based phosphorylation assays
12/23/2004WO2004055169A3 Cytochrome c acetylation
12/23/2004WO2004047754A3 Loc169505 as modifier of the apc and axin pathways and methods of use
12/23/2004WO2004046375A3 Method for the detection of microorganisms in pharmaceutical products
12/23/2004WO2004045499A3 Identification of actinobacillus actinomycetemcomitans antigens for use in the diagnosis, treatment, and monitoring of periodontal diseases
12/23/2004WO2004044122A3 Parallel or antiparallel, homologous or complementary binding of nucleic acids or analogues thereof to form duplex, triplex or quadruplex complexes
12/23/2004WO2004035753A3 Lmna gene and its involvement in hutchinson-gilford progeria syndrome (hgps) and arteriosclerosis
12/23/2004WO2004020575A3 Methods and systems for detection and isolation of a nucleotide sequence
12/23/2004WO2004016757A3 Methods, compositions and kits for producing nucleic and acid sequences
12/23/2004WO2004005479A3 A high resolution typing system for pathogenic borrelia
12/23/2004WO2003106692A3 Methods for the identification of all-antigens and their use for cancer therapy and transplantation
12/23/2004WO2003104427A3 Methods and compositions for detecting cancers
12/23/2004WO2003101497A8 Knockout mice and their use
12/23/2004WO2003100030A3 Kidney toxicity predictive genes
12/23/2004WO2003089898A3 Determining biochemical markers of progression and therapy monitoring and specification, therapeutic lead molecules, and target biochemical systems applied to stroke
12/23/2004WO2003050236A3 Human genes and gene expression products isolated from human prostate
12/23/2004WO2003037167A3 Pathway of rantes-mediated chemokine synthesis in astrocytes and methods of use therefor
12/23/2004WO2003035910A9 Transfection kinetics and structural promoters
12/23/2004WO2003021221A3 Method for discovering new infectious particles
12/23/2004WO2003016574A9 Analysis of gene expression profiles using sequential hybridization
12/23/2004US20040261144 Identification of soybeans having resistance to Phytophthora sojae
12/23/2004US20040261138 Porcine melanocortin-4 receptor (MC4R) genes; detecting point mutation in aspartic acid/asparagine codon via polymerase chain reaction; restriction fragment length polymorphism; kits
12/23/2004US20040260079 Cardiac-cell specific enhancer elements and uses thereof
12/23/2004US20040259848 Applying fungicide to plants, crops
12/23/2004US20040259829 Carboxylesterase; antitumor agents; drug screening; bioassay
12/23/2004US20040259793 Methods and compositions for modulating proteins modified in preconditioning against ischemia/hypoxia
12/23/2004US20040259789 Stimulant gene expression of peptide
12/23/2004US20040259781 Drug screening ; polypeptide interfers with binding of fibronectin to; anticancer agents; antihistamines, antiarthritic agents, autoimmune disease, wound healing agents
12/23/2004US20040259764 Reticulocyte depletion signatures
12/23/2004US20040259248 RNA interference mediating small RNA molecules
12/23/2004US20040259247 short interfering RNAs for use treating diseases, in protein separation or purification, in drug screening; cell with target gene-specific knockout phenotype; double stranded RNA; RNA fragments are the sequence-specific mediators of RNAi (RNA interference)
12/23/2004US20040259243 using a cell line with increased sensitivity for infection for the rapid detection of enterovirus by innoculating the cells with the sample and observing; poliovirus, Coxsackie A virus, Coxsackie B virus, or echovirus; using transgenic buffalo green monkey kidney cell lines; producing enteroviruses
12/23/2004US20040259238 filter has a physical barrier to isolate the cell sample on the filter and a growth detection circuitry associated with the filter identifies a cell growth rate using electrical measurements to detect live cells; use in microfluidics
12/23/2004US20040259229 Novel technology for genetic mapping
12/23/2004US20040259226 detecting the presence, absence, or amount of a Chaperonin 60 (cpn60) marker specific for one or more microbes used in bioterrorism; immunoassays and nucleic acid based assays such as fluorescence in situ hybridization (FISH); kits
12/23/2004US20040259222 Novel group of $g(a)-amylases and a method for identification and production of novel $g(a)-amylases
12/23/2004US20040259201 Recombinant surfactant protein D compositions and methods of use thereof
12/23/2004US20040259199 32544, Novel human phospholipase C and uses thereof
12/23/2004US20040259193 using a polypeptide having JAB subunit or the JAM domain that confers isopeptidase activity to deconjugate a modifier protein from a target protein; e.g. de-ubiquitination; use in drug screening
12/23/2004US20040259184 useful for identifying or quantifying TRAP in isolated osteoclast cells or osteoclasts differentiated from RAW264.7 monocyte-macrophage cells; diagnosing bone resorption disorders
12/23/2004US20040259183 Method for measuring chemical groups attached to biological molecules
12/23/2004US20040259181 Enzyme substrates
12/23/2004US20040259179 evaluating the likelihood of whether an individual will benefit from treatment with an agent for reducing risk of a future cardiovascular event, such as atherosclerosis, myocardial infarction and stroke by measuring the level of sterols
12/23/2004US20040259176 facilitating death of cancer cells by inhibiting tissue transglutaminase; anticancer agent drug design using three-dimensional structure of a crystallized tissue transglutaminase
12/23/2004US20040259173 Method of determining target protein of drug
12/23/2004US20040259171 P2Y4 antibody and methods of use
12/23/2004US20040259169 Methods for selection for efficient animal growth
12/23/2004US20040259166 Methods for designing inhibitors of serine/threonine kinases and tyrosine kinases
12/23/2004US20040259165 Non-oligomerizing tandem fluorescent proteins
12/23/2004US20040259160 drug screening for agents that induce glucose-stimulated insulin production to treat type-2 diabetes; "beta-TRP" polypeptide refers to a calcium channel; transforming islet cells with expression cassettes encoding beta-TRP into diabetic islet cells to improve glucose-stimulated insulin production
12/23/2004US20040259159 Role of LDL receptor protein-1 (LRP-1) in Alzheimer's disease
12/23/2004US20040259152 determining the effect of a test compound on tissue remodeling modulator protein (TRMP), which is alpha 5 beta 1 integrin bioactivity; diagnosis, antisense agents, and tissue-targeted therapy via drug-antibody conjugate of tumors and cancer (tissue remodeling disorder)
12/23/2004US20040259151 containing a prosthetic group and/or subunits on the surface of a host cell using the transporter domain of an autotransporter; use of host cell for toxicity monitoring, drug screening or synthesis of organic substances such as enzyme substrates, drugs, hormones, intermediates thereto
12/23/2004US20040259148 electrochemiluminescence (ECL) assay apparatus with ECL-inactive electrode surface having a first assay-ligand immobilized thereon and an ECL-active microparticle having a second assay ligand immobilized thereon
12/23/2004US20040259147 Gene causative of rothmund-thomson syndrome and gene product
12/23/2004US20040259146 making libraries; synthesizing nucleic acids of predetermined sequence on a substrate and localizing each to a defined area of a substrate, then introducing harvested nucleic acid molecules into vectors; individual synthesis of nucleic acid molecules is costly, inefficient
12/23/2004US20040259144 calculating a prognostic index by selecting coefficients for each of a plurality of nuclear pleomorphic features using a numerical regression; prognosis of the likely time to recurrence in the patient
12/23/2004US20040259142 Products and methods
12/23/2004US20040259141 identifying sequences differing by one or more single base changes, insertions, deletions, or translocations in a plurality of target nucleotide sequences; includes a ligation phase, a capture phase, and a detection phase; multiplex detection
12/23/2004US20040259139 Novel proteins in enteroaggregative escherichia coli (EAEC) useful for diagnosis and therapy of EAEC infections
12/23/2004US20040259136 diagnosis of arthritis based on elevated test amount of a zeta PKC gene product; drug screening, antisense agents and short interfering RNA (siRNA)
12/23/2004US20040259135 Biosynthetic labeling and separation of RNA
12/23/2004US20040259134 nucleic acid of given sequence encoding glycerol kinase (GK) gene with a novel mutant allele
12/23/2004US20040259133 precipitation ribonucleic acids by incubating with preservative in an aqueous solutions, then staining and analyzing the cells for messenger ribonucleic acid expression patterns by fluorescence in-situ hybridization
12/23/2004US20040259131 based on interactions between proximally-bound nucleic acid tags; interaction generating at least one tag having novel sequence; reagent kit containing Mosaic Ends recognition sequences, nucleic acid tags comprise LoxP sites, Cre recombinase and Tn5 transposase
12/23/2004US20040259130 introducing a nucleic acid comprising a non-lethal marker gene into an avian cell by electroporating and allowing the cell to undergo a cellular division; injecting said cell into an avian embryo to produce a transgenic chick; use to make exogenous proteins such as human antibodies
12/23/2004US20040259128 Methods and compositions for detecting the presence of target nucleic acids in a sample
12/23/2004US20040259127 Approaches to identifying genetic traits in animals
12/23/2004US20040259125 Methods, systems and apparatus for identifying genetic differences in disease and drug response
12/23/2004US20040259124 Methods for oligonucleotide probe design
12/23/2004US20040259122 Autocatalysis/yeast two-hybrid assay
12/23/2004US20040259121 Detection of fusarium species infecting corn using the polymerase chain reaction
12/23/2004US20040259120 Detection of fusarium species infecting corn using the polymerase chain reaction
12/23/2004US20040259119 apparatus; sequences are labelled and applied to an array of oligonucletides on at least two defined cells under hybridizing conditions; analysis of known point mutations, DNA fingerprinting, characterization of mRNAs, sequence determination; amplification not needed
12/23/2004US20040259118 Methods and compositions for nucleic acid sequence analysis
12/23/2004US20040259117 Screening assay based on the forkhead transcription factor-dependent SOD-3 promoter
12/23/2004US20040259116 Hairpin primer amplification
12/23/2004US20040259115 amplifying a nucleic acid using two reverse transcriptases that work synergistically under the same buffer conditions to produce more complete cDNAs that are useful for expression profiling; relieve the inhibition of RT PCR (reverse transcriptase polymerase chain reaction)
12/23/2004US20040259114 Coactivators in the diagnosis and treatment of breast cancer
12/23/2004US20040259113 by determining the presence of kallikrein protein, hK2 polypeptide of hK2 RNA in a physiological sample
12/23/2004US20040259111 Once a binding assay design and sample is received from a scientist, an experiment design is automatically prepared for generating a binding-ready biological sample to be used by the binding assay such as hybrization assay; can run 24 hours a day, improving efficiency; high throughput
12/23/2004US20040259110 Gene PRV-1 and its use
12/23/2004US20040259109 Method of analyzing prokaryotic gene expression
12/23/2004US20040259108 Compositions and methods for detecting west nile virus
12/23/2004US20040259106 Methods and compositions for whole genome amplification and genotyping
12/23/2004US20040259105 Multiplex nucleic acid analysis using archived or fixed samples
12/23/2004US20040259104 Test
12/23/2004US20040259103 NKR (Natural Killer Receptor); rapidly analyze physiological and pathological situations linked to these repertoires; use in diagnosise/prognosis of patients for transplant acceptance, resistance to infections and disease, and in drug screening for autoimmune diseases, antitumor agents, and antibiotics
12/23/2004US20040259102 Detection of chemical ligation using fluorescence quenching leaving groups
12/23/2004US20040259101 Methods for disease screening
12/23/2004US20040259100 used to genotype individuals on a genome-wide scale; simultaneously detecting large numbers of typable loci for an amplified representative population of genome fragments using genetic probes having sequences corresponding to the typable loci
12/23/2004US20040259099 uses nucleotide sequence information differences between individuals to offer semantic information useful for each individual while preventing leakage or illegal use of nucleotide sequence information
12/23/2004US20040259097 Method for the in vitro synthesis of short double stranded rnas
12/23/2004US20040259096 Receptor capture assay
12/23/2004US20040259095 identify water-borne organisms associated with harmful algal bloom using amplification through real time PCR and then detecting the amplicons using species-specific labeled probe; prevents invasive species such as Zebra mussels from entering lakes; kits and probes
12/23/2004US20040259091 Luminescence detecting device and luminescence detecting microarray plate
12/23/2004US20040259090 Use of a biochip for the diagnosis of sepsis or sepsis related syndrome
12/23/2004US20040259088 Reacting sample with probe support containing a base complementary base then detecting hybridized complex; microarrays
12/23/2004US20040259087 Diagnosing atherosclerosis by determining presence or absence of single nucleotide polymorphism (SNP) in codon of lipoprotein-associated phospholipase A2 (Lp-PLA2); point mutations; kits