Patents for C12P 29 - Preparation of compounds containing a naphthacene ring system, e.g. tetracycline (146)
02/2015
02/26/2015US20150056651 Microorganism production of high-value chemical products, and related compositions, methods and systems
02/11/2015CN104342477A 一种四环素的制备方法 Method for preparing tetracycline
02/11/2015CN104342476A 一种摇瓶培养基的制备方法 Shake flask method for preparing a medium
08/2014
08/06/2014CN103966298A 一种四环素菌渣的循环利用方法 Recycling method tetracycline residue bacteria
07/2014
07/30/2014CN102864202B 一种发酵生产四环素的方法 The method of producing a fermented tetracycline
06/2014
06/18/2014CN103865946A Terramycin high-yielding method based on metabolism regulation
05/2014
05/07/2014CN103773831A 一种金色链霉菌发酵生产金霉素的新型培养基和培养方法 A Streptomyces fermentation process for the production of new media and culture chlortetracycline
03/2014
03/19/2014CN103642886A Medium for producing demethylchlortetracycline by fermenting streptomyces aureus and culturing method
03/19/2014CN103205481B Method for improving aureomycin yield as well as recombinant expression vector and genetic engineering bacterium of aureomycin
03/05/2014CN103614447A A fermentation production method for aureomycin by utilizing cane molasses in place of a portion of corn starch
03/05/2014CN103614446A Fermentation technology for increasing the aureomycin yield by adding metal ions
03/05/2014CN103614445A A fermentation production method for aureomycin by utilizing mycoprotein in place of a portion of yeast powder
02/2014
02/26/2014CN103602714A Method for producing tetracycline by fermentation of streptomyces aureus
01/2014
01/01/2014CN102899377B Preparation method of chlortetracycline premix
09/2013
09/18/2013CN103305545A Method for improving terramycin yield
08/2013
08/28/2013CN103266160A Method for lowering down proportion of by-product produced in fermentation of demethylchlortetracycline
07/2013
07/17/2013CN103205481A Method for improving aureomycin yield as well as recombinant expression vector and genetic engineering bacterium of aureomycin
06/2013
06/12/2013CN103146792A Culture medium for producing oxytetracycline through streptomyces rimosus fermentation and fermentation method
05/2013
05/16/2013US20130122541 Microorganism production of high-value chemical products, and related compositions, methods and systems
03/2013
03/13/2013CN102965315A Streptomyces rimosus mutant strain and preparation method and application thereof
02/2013
02/26/2013US8383392 Transformant and method for production of non-natural antibiotic
01/2013
01/30/2013CN102899377A Preparation method of chlortetracycline premix
01/17/2013US20130017571 Pullulanase Variants and Uses Thereof
01/09/2013CN102864202A Method for producing tetracycline through fermenting
11/2012
11/01/2012US20120276585 Method for producing fermentation products from lignocellulose-containing material
08/2012
08/23/2012US20120214197 Polypeptides Having Glucoamylase Activity and Polynucleotides Encoding Same
08/23/2012US20120214196 Polypeptides Having Glucoamylase Activity And Polynucleotides Encoding Same
08/07/2012US8236928 Genes differentially expressed in breast cancer
08/2011
08/04/2011CA2788045A1 Microorganism production of high-valve chemical products, and related compositions, methods and systems
11/2010
11/18/2010US20100291622 Novel compound, process for production thereof, and use thereof
05/2010
05/20/2010US20100124583 Processing biomass
02/2010
02/23/2010US7666631 Adenosylmethionine synthetase from streptomyces sp., gene sequences coding the same and method for mass production of secondary metabolites including antibiotics thereof
02/11/2010US20100035847 Genes for biosynthesis of tetracycline compounds and uses thereof
10/2009
10/20/2009US7605144 Proliferation inhibition of pathological cells; prodrug converted to or releasing cellular toxin
07/2009
07/09/2009WO2009085068A1 Compositions comprising artemisinic acid and methods of their preparation
03/2009
03/17/2009US7504112 Culturing Streptomyces aureofaciens to produce chlorotetracycline in a fermentation broth; reducing the broth to produce chlorotetracycline solids; drying; granulating; screening to produce particles of 80-10 mesh; and adding the wrong sized particles to a 2nd Streptomyces aureofaciens broth
08/2008
08/19/2008US7413877 Bacterial expression of bowman-birk protease inhibitors and variants thereof
07/2008
07/17/2008WO2007139972A8 Expression of the cysteine protease legumain in vascular and inflammatory diseases
04/2008
04/09/2008CN101160524A Compositions and methods for classifying biological samples
01/2008
01/24/2008WO2007139972A3 Expression of the cysteine protease legumain in vascular and inflammatory diseases
01/08/2008CA2119209C An animal feed additive based on fermentation broth, a process for its production and its use
12/2007
12/06/2007CA2652895A1 Expression of the cysteine protease legumain in vascular and inflammatory diseases
11/2007
11/28/2007EP1859266A2 Compositions and methods for classifying biological samples
09/2007
09/27/2007DE102006013914A1 Neue 7,12-Dihydro-7,12-dioxo-benz[a]anthracene, deren Herstellung und deren Verwendung als Arzneimittel New 7,12-dihydro-7,12-dioxo-benz [a] anthracene, their preparation and their use as medicaments
08/2007
08/08/2007EP1740566B1 Hki10311129, novel antibiotic, method for producing the same and the use thereof
02/2007
02/08/2007WO2006091734A3 Compositions and methods for classifying biological samples
01/2007
01/10/2007EP1740566A1 Hki10311129, novel antibiotic, method for producing the same and the use thereof
01/09/2007US7160869 Biologically active metal-containing nucleic acids
01/02/2007US7157438 Rhob as a suppressor of cancer cell growth and cell transformation
11/2006
11/14/2006US7135463 inhibiting the growth of a cancerous cell by contacting cell with an effective amount of a RhoB protein, or a variant of the RhoB protein; alone or in combination with additional anti-cancer agents, such as cytotoxic agents (e.g., 5-flurouracil)
09/2006
09/19/2006US7109295 Fusion polypeptide (chimera); a zinc finger (ZF) monomer, e.g., a Cys2His2 zinc finger protein, that recognizes a DNA sequence, a dimerization domain of a tetracycline repressor, containing a drug-dependent switch, and an accessory domain to alter the expression of the target gene
08/2006
08/31/2006CA2598889A1 Compositions and methods for classifying biological samples
05/2006
05/31/2006EP0861321B1 Phosphopantetheinyl transferases and uses thereof
05/2005
05/26/2005US20050112728 Polynucleotide coding enzyme catalyst for biosynthesis; gene expression; forming antibiotic
04/2005
04/20/2005EP1417313A4 Adenosylmethionine synthetase from streptomyces sp., gene sequences coding the same and method for mass production of secondary metabolites including antibiotics thereof
03/2005
03/17/2005US20050059156 Detecting presence of organic chemical contaminant in an anthracycline product via chromatographic separation and DNA elution
02/2005
02/17/2005WO2005014855A1 Method for detecting contaminants in pharmaceutical anthracycline products
02/16/2005EP1432811A4 Cell separation matrix
01/2005
01/18/2005US6844006 Process and apparatus for the preparation of chlortetracycline-containing animal feed compositions
08/2004
08/10/2004US6773717 Process and apparatus for the preparation of chlortetracycline-containing animal feed compositions
07/2004
07/13/2004US6761899 Particulate animal feed supplements and processes for the preparation thereof
06/2004
06/30/2004EP1432811A1 Cell separation matrix
05/2004
05/12/2004EP1417313A1 Adenosylmethionine synthetase from streptomyces sp., gene sequences coding the same and method for mass production of secondary metabolites including antibiotics thereof
05/2003
05/13/2003US6562615 Apparatus for use in the generation of animal feed which contain preferential antibiotics
05/01/2003CA2463467A1 Cell separation matrix
01/2003
01/30/2003WO2003008591A1 Adenosylmethionine synthetase from streptomyces sp., gene sequences coding the same and method for mass production of secondary metabolites including antibiotics thereof
01/14/2003US6506402 Chlortetracycline-containing animal feed compositions and methods for their use
12/2002
12/17/2002CA2047833C Cloning of the biosynthetic pathway genes for chlortetracycline production from streptomyces aureofaciens and their expression in steptomyces lividans
07/2002
07/03/2002CN1086918C Method for producing animal feed supplement based on fermentation broth
10/1999
10/12/1999US5965429 Streptomyces aureofaciens cell with a recombinant ctc 11 gene whose expression is enhanced compared to wild-type; for industrial biosynthesis of antibiotics
02/1999
02/02/1999US5866410 Mixture of two plasmids for cloning
11/1998
11/24/1998US5840358 Granulation, compaction, drying in fluidized bed in one step
03/1998
03/19/1998WO1998011230A1 Polyketide synthases for pradimicin biosynthesis and dna sequences encoding same
03/05/1998DE19635642A1 New di:hydro-benzoÝa¨naphthacene-quinone antibiotics
02/1998
02/04/1998EP0657412B1 Saintopin derivative
01/1998
01/21/1998CN1170515A Process for preparation of animal feed supplement based on fermentation broth
12/1997
12/03/1997EP0809940A2 Process for producing an animal feed additive based on fermentation broth
11/1997
11/30/1997CA2206587A1 A process for the preparation of an animal feed supplement based on fermentation broth
02/1997
02/11/1997CA2008628C Substance uct-1003 and process for producing the same
12/1996
12/31/1996US5589385 Cloning of the biosynthetic pathway for chlortetracycline and tetracycline formation and cosmids useful therein
12/18/1996CN1033591C Production of pradimicin antibiotics
08/1996
08/29/1996WO1996026199A1 Active bio-compounds
05/1996
05/30/1996WO1996016014A1 Active bio-compounds
04/1996
04/23/1996US5510501 Saintopin derivatives
08/1995
08/15/1995CA1336695C Dactylocycline a and dactylocycline b
06/1995
06/27/1995US5427941 Culture product; 7-chloro-8-methoxytetracyline isolated from antibiotic ES-119 AND antibiotic Tet. 7, which are produced by fermentation of mutants of microorganism
06/21/1995CN1103890A Method for man power increasing oxygen for increasing yield when aerobic fermentation
06/14/1995EP0657412A1 Saintopin derivative
04/1995
04/26/1995EP0649899A1 Novel method for culturing filamentous fungi, carrier for immobilizing filamentous fungi and immobilized fungus composition for culturing
12/1994
12/20/1994US5374552 Pure culture of Actinomadura species, mutants
06/1994
06/09/1994WO1994012458A1 Saintopin derivative
06/09/1994CA2129021A1 Saintopin derivatives
04/1993
04/07/1993EP0311640B1 Higher alkyl pyrrolidone extractants for water soluble phenolic or carboxylic antibiotics
03/1993
03/16/1993US5194371 Production of pradimicin antibiotics
02/1993
02/24/1993CN1069286A Production of pradimicin antibiotics
02/03/1993EP0525588A2 Production of pradimicin antibiotics by actinomadura strain
02/02/1993US5183758 Production of 7-chloro-3-methoxy-2'-N-methyltetracycline with Actinomadura brunnea
02/01/1993CA2071140A1 Production of pradimicin antibiotics by fermentation
01/1992
01/29/1992EP0468220A2 Cloning of the biosynthetic pathway genes for chlortetracycline production from streptomyces aureofaciens & their expression in steptomyces lividans
01/29/1992EP0468217A2 A bifunctional cosmid useful for cloning actinomycete DNA
1 2