Patents for C12P 21 - Preparation of peptides or proteins (112,499)
05/1985
05/09/1985WO1985001958A1 Production of heterodimeric human fertility hormones
05/09/1985WO1985001941A1 Method for the purification and isolation of blood clotting proteins using conformation specific antibodies
05/08/1985EP0140864A1 Externalization of products of bacteria
05/08/1985EP0140689A2 Hybrid cell lines producing monoclonal antibodies directed against treponema and use thereof for immuno-diagnosis of treponemal infections
05/08/1985EP0140127A1 Process for the preparation of immune interferon
05/08/1985EP0140084A1 Process for the preparation of insulin derivatives with a C-terminally elongated B-chain, basically modified insulin derivatives, compositions containing them and their use
05/07/1985US4515891 Process for the production of disaccharide-tripeptide and disaccharide-tetrapeptide
05/07/1985CA1186629A1 Biologically active substance, process for preparing the substance and immunoactive composition
05/02/1985EP0139501A2 The manufacture and expression of genes for thaumatin
05/02/1985EP0139417A1 Vaccines based on membrane bound proteins and process for making them
05/02/1985EP0139416A2 Molecularly cloned diagnostic product and method of use
05/02/1985EP0139389A1 Antiidiotypic monoclonal antibody reagents and immunoassays employing antiidiotypic monoclonal antibody reagents
05/02/1985EP0139383A1 Method for expressing foreign genes in schizosaccharomyces pombe and the use in therapeutic formulations of the products, DNA constructs and transformant strains of schizosaccharomyces pombe usable in such method and their preparation
05/02/1985EP0139216A2 Adult T cell leukemia virus antigen peptide
04/1985
04/30/1985US4514498 Urogential disorders
04/30/1985CA1186256A1 Use of isotropic, porous-wall polymeric membrane, hollow-fibers for culture of microbes and other living cells
04/25/1985WO1985001746A1 The manufacture and expression of genes for thaumatin
04/25/1985WO1985001659A1 Monoclonal antibodies against endotoxin of gram-negative bacteria
04/24/1985EP0138377A1 Lewis blood group phenotype assay
04/24/1985EP0138222A2 Preparation of monoclonal anti-protein C antibodies
04/24/1985EP0138167A1 Method for purification of HBs antigen
04/24/1985EP0138101A1 Genetically engineered organisms expressing surface proteins of T. Cruzi
04/24/1985EP0138087A1 Immune interferon and method for its purification
04/24/1985EP0137869A2 Derived nisin producing microorganisms, method of production and use and products obtained thereby
04/24/1985EP0137822A1 Specific antibody to the native form of 2'5'-oligonucleotides, the method of preparation and the use as reagents in immunoassays or for binding 2'5'-oligonucleotides in biological systems.
04/23/1985CA1185909A1 Heteropolysaccharide s-194
04/17/1985EP0137691A1 Production of immune interferon and its mRNA
04/17/1985EP0137689A1 GRF analogs
04/17/1985EP0137657A2 Monoclonal antibodies
04/17/1985EP0137633A1 Method of expressing alpha-1-antitrypsin in bacteria and its use in therapeutic formulations, and vectors and bacteria for such method and their production
04/17/1985EP0137345A2 Membrane-associated proteins (MP-2), process for obtaining them and their application
04/16/1985US4511505 Threonine derivatives
04/11/1985WO1985001517A1 PRODUCTION OF cDNA REPRESENTING HEPATITIS A VIRAL SEQUENCES
04/11/1985WO1985001515A1 T-cell growth factor of the gibbon ape
04/10/1985EP0136907A2 A xenogeneic expression control system, a method of using it, expression vectors containing it, cells transformed thereby and heterologous proteins produced therefrom
04/10/1985EP0136835A2 Process for the preparation of antibody compositions of therapeutic agents having an extended serum half-life
04/10/1985EP0136829A2 Improved expression vector and use thereof
04/10/1985EP0136620A1 Homogeneous immune interferon fragment
04/10/1985EP0136490A2 DNA plasmids
04/10/1985EP0136472A1 Production of secretin
04/09/1985US4510132 Compounds for use in antibacterial therapy
04/09/1985CA1185178A1 Method for purifying interferon
04/03/1985EP0136215A2 Method and materials for development of immunological responses protective against malarial infection
04/03/1985EP0135712A2 Antigens and monoclonal antibodies reactive against sporozoites of eimeria spp.
04/02/1985US4508643 Human chorionic govadotropin; low cross-reactivity
04/02/1985CA1184899A1 Glycoprotein
04/02/1985CA1184862A1 Filtration method for cell produced antiviral substances
03/1985
03/28/1985WO1985001296A1 Yeast hybrid vectors
03/27/1985EP0135347A1 Human renin and cDNA encoding therefor
03/27/1985EP0135159A2 Monoclonal antibody having specificity for the double-stranded conformation of native DNA and diagnostic methods using same
03/27/1985EP0135073A2 Antigens and monoclonal antibodies reactive against merozites of eimeria spp.
03/27/1985EP0134803A1 Monoclonal antibody
03/20/1985EP0134673A1 Improved plasmid vector and use thereof
03/20/1985EP0134631A1 Peptides, pharmaceutical compositions, genes, vectors, host organisms, processes for their production and diagnostic reagents
03/20/1985EP0134552A2 Monoclonal antibody with a high affinity for digoxin
03/20/1985EP0134479A1 Modified proteinase inhibitors, process for their preparation and pharmaceutical compositions containing them
03/20/1985EP0134385A2 A protein having cell growth stimulating action, composition thereof and method for producing the same
03/20/1985EP0134247A1 Protein with oncostatic effect, process for its preparation, and oncostatic drug containing it
03/14/1985WO1985001067A1 Recombinant materials and methods for producing human connective tissue-activating peptide-iii and analogs thereof
03/14/1985WO1985001066A1 Process for producing peptide
03/14/1985WO1985000977A1 Vaccine and antigen against paludism and preparation process thereof
03/14/1985WO1985000976A1 Method and materials for development of immunological responses protective against malarial infection
03/14/1985WO1985000974A1 Antibody compositions of therapeutic agents having an extended serum half-life
03/13/1985EP0134085A1 DNA encoding a GRF precursor
03/13/1985EP0134048A1 Molecular cloning and expression in industrial microorganism species
03/12/1985US4504644 Sunscreen agents
03/12/1985US4504394 Process for the treatment of organic fall-out products
03/05/1985US4503048 Pyridine soluble extract of a microorganism
03/05/1985CA1183470A1 Hybrid cell line for producing monoclonal antibody to a human prothymocyte antigen, antibody, and methods
03/05/1985CA1183469A1 Hybrid cell line for producing complement-fixing monoclonal antibody to human suppressor t cells, antibody, and method
03/05/1985CA1183451A1 Method for producing a csap tryptic peptide and anti- csap antibodies
02/1985
02/28/1985WO1985000832A1 Production of streptococal m protein immunogens and molecular probes
02/28/1985WO1985000829A1 Dna plasmids
02/28/1985WO1985000807A1 Polypeptide-induced monoclonal antibodies to oncoproteins
02/27/1985EP0133599A2 Vaccines and compositions against hepatitis B viral infections
02/27/1985EP0133551A2 Monoclonal antibody which recognizes a structure which is common to the human interleukin-2 (TCGF) and to the light chain lambda of human immunoglobulin, and hybridoma cell lines producing this monoclonal antibody
02/27/1985EP0133540A1 Receptor assays using labeled monoclonal anti-idiotypic antibodies
02/26/1985US4501693 Hydrolyzing proteoglycans with lysozyme
02/26/1985CA1183092A2 Production of yeast cells at high cell densities
02/20/1985EP0133403A2 Nucleotide sequence coding for the signal peptide of diphteria toxin, vector containing this nucleotide sequence, its use in the transformation of microorganisms and peptide compositions obtained therefrom.
02/20/1985EP0133284A2 Process for isolating and purifying interferon
02/20/1985EP0133282A1 Preparation of acidamide-carboxy-terminal polypeptides
02/20/1985EP0051071B1 Tryptophane derivative and process for preparing same
02/13/1985EP0133079A2 Process for the separation and isolation of nosiheptide
02/13/1985EP0133044A1 Stabilising foreign proteins, and plasmids for use therein
02/13/1985EP0132770A1 Insulin derivatives, processes for their preparation, their use and pharmaceutical compositions for the treatment of diabetes mellitus
02/13/1985EP0132732A2 Homologues from aprotinine whose lys 15 amino acid is substituted by other amino acids, process for their preparation and their use as medicaments
02/13/1985EP0132488A2 Rat antibody to human chorionic gonadotropin
02/12/1985US4499189 Bacteria carrying plasmid having temperature dependent plasmid copy number
02/12/1985US4499014 Method for purifying gamma-interferon
02/12/1985CA1182447A1 Derivatives of actaplanin
02/12/1985CA1182407A1 MICROBIOLOGICAL SYNTHESIS OF .beta. ENDORPHIN
02/12/1985CA1182406A1 Hybrid cell line for producing complement-fixing monoclonal antibody to human t cells, antibody, and methods
01/1985
01/31/1985WO1985000382A1 Molecular cloning and expression in industrial microorganism species
01/31/1985WO1985000381A1 Proteins, pharmaceutical compositions, genes, vectors, host organisms and processes for their production
01/31/1985WO1985000369A1 Hybrid dna synthesis of epidermal growth factor
01/30/1985EP0132349A2 Antibiotic called "chloropolysporin", a process for its preparation, and its therapeutic and veterinary use
01/29/1985CA1181702A1 Hybrid cell line for producing monoclonal antibody to a human thymocyte antigen, antibody, and methods
01/23/1985EP0132125A2 A protein having antitumor activity
01/23/1985EP0131878A2 Process for producing human monoclonal antibodies