Patents for C12N 9 - Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes (141,535)
01/2003
01/02/2003US20030003078 A mutant bacterial strain Xanthomonas orzae pv. orzae (BXO65); rifampin antibiotic resistance; develop bactericide by identify Shikimate dehydrogenase pathway inhibitors in bacteria
01/02/2003US20030003077 A genetic engineered adenoviral vector contains an adenoviral genome from which the open reading frames E1 and/or E3 were deleted and a therapeutic gene or a DNA sequence that encodes for therapeutic proteins useful in fibrosis treatment
01/02/2003US20030000667 Treating polyamine-epihalohydrin creping resin with enzymatic agent under conditions to at least one of inhibit, reduce and remove chloropropanediol forming species to obtain gelation storage stable resin
01/02/2003EP1270739A1 Engineered secreted alkaline phosphatase (seap) reporter genes and polypeptides
01/02/2003EP1270735A1 Process for producing aglycon by using diglycosidase and flavor-improved food containing the aglycon and converting agent to be used in the process
01/02/2003EP1270731A1 Method for increasing the content of carotinoids in transgenic plants
01/02/2003EP1270730A1 Process for producing polypeptide having disulfide bond
01/02/2003EP1270729A1 Dna molecule coding for a polygalacturonase of strawberry and the uses thereof
01/02/2003EP1270728A1 Process for producing avermectin derivative
01/02/2003EP1270727A1 Salutaridinol 7-O-acetyltransferase and derivatives thereof
01/02/2003EP1270722A1 Cytochrome p-450 gene cluster from rhodococcus ruber and uses thereof in ether fuel cleavage
01/02/2003EP1270721A1 Recombinant DNA sequences encoding feedback inhibition released enzymes, plasmids comprising the recombinant DNA sequences, transformed microorganisms useful in the production of aromatic amino acids, and a process for preparing aromatic amino acids by fermentation
01/02/2003EP1270720A2 Activated rec-D-Hydantoinases
01/02/2003EP1270594A1 Antibodies to peptide from a soluble fragment of acetylcholinesterase
01/02/2003EP1270577A1 Furoisoquinoline derivatives, process for producing the same and use thereof
01/02/2003EP1269836A1 Animals with high histamine productivity
01/02/2003EP1268831A2 Method for the production of leguminous plants with increased protein content and longer seed filling duration
01/02/2003EP1268830A2 Cell cycle stress-related proteins and methods of use in plants
01/02/2003EP1268828A2 Signal transduction stress-related proteins and use in plants
01/02/2003EP1268827A2 Methods of selection and development of plants having improved root quality and root lodging resistance
01/02/2003EP1268825A1 Control of aerial branching
01/02/2003EP1268824A2 Promoter sequence of 3-phosphoglycerate kinase gene 1 of rhizopus oryzae and its use
01/02/2003EP1268821A2 Helicase inhibitors
01/02/2003EP1268820A2 Estrogen-regulated myo-inositol phosphate synthase: compositions and methods of use
01/02/2003EP1268819A2 Muskmelon (cucumis melo) hydroperoxide lyase and uses thereof
01/02/2003EP1268818A2 18221, dual specificity phosphatase and uses thereof
01/02/2003EP1268817A1 Human pyruvate dehydrogenese phosphatase
01/02/2003EP1268816A2 Calcium-binding regulatory subunit
01/02/2003EP1268815A2 Triazine degrading enzymes
01/02/2003EP1268814A2 Regulation of human leucine aminopeptidase-like enzyme
01/02/2003EP1268813A2 Thermophilic polymerase iii holoenzyme
01/02/2003EP1268812A2 Vectors for gene therapy
01/02/2003EP1268811A2 Pi3k - regulatory subunit homologue
01/02/2003EP1268810A2 Polynucleotides that control delta-6-desaturase genes and methods for identifying compounds for modulating delta-6-desaturase
01/02/2003EP1268809A2 32142, 21481, 25964, 21686, novel human dehydrogenase molecules and uses therefor
01/02/2003EP1268808A1 Mutants of lactobacillus casei defective in carbon catabolism regulation
01/02/2003EP1268791A2 Brca-1 regulators and methods of use
01/02/2003EP1268764A2 Method for obtaining nucleic acids from an environment sample
01/02/2003EP1268757A1 Nitrilase from rhodococcus rhodochrous ncimb 11216
01/02/2003EP1268756A2 Methods and compositions for modulating integrin-mediated cell-cell interactions
01/02/2003EP1268755A1 Method to identify polypeptides with protease activity
01/02/2003EP1268753A2 Human protein tyrosine phosphatase, encoding dna and uses thereof
01/02/2003EP1268752A1 Production of lutein in microorganisms
01/02/2003EP1268751A2 Xylosyltransferase and isoforms thereof
01/02/2003EP1268549A2 Method of identifying inhibitors of tie-2
01/02/2003EP1268535A2 Nematodes as model organisms for the investigation of neurodegenerative diseases, in particular parkinsons disease, uses and methods for the discovery of substances and genes which can be used in the treatment of the above disease states and identification of a nematode gene.
01/02/2003EP1268531A2 Method for the production of bacterial toxins
01/02/2003EP1268525A2 Macrocyclic ns3-serine protease inhibitors of hepatitis c virus comprising n-cyclic p2 moieties
01/02/2003EP1268519A2 Inhibitors of serine proteases, particularly hepatitis c virus ns3 protease
01/02/2003EP1268509A1 Mammalian sphingosine kinase type 2 isoforms, cloning, expression and methods of use thereof
01/02/2003EP1267940A1 Compounds for targeting
01/02/2003EP1267914A1 Use of lyosomal acid lipase for treating atherosclerosis and related diseases
01/02/2003EP1267811A1 Encymatical colorant
01/02/2003EP1226273A4 Multimerized dbh enhancer domains
01/02/2003EP1127259A4 Thromboplastin reagents and methods for preparing and using such reagents
01/02/2003EP1115886A4 Secreted renilla luciferase
01/02/2003EP1100949A4 Fusion products containing insoluble proteinaceous tag
01/02/2003EP0810282A4 Process for obtaining improved strains of trichoderma spp.
01/02/2003EP0745131B1 Targeting gene therapy
01/02/2003EP0723592B1 Alpha-1,4-glucan lyase from a fungus infected algae, its purification, gene cloning and expression in microorganisms
01/02/2003EP0662138B1 Long wap promoter for mammary expression of human protein c
01/02/2003EP0630408B1 PRODUCTION OF $i(ASPERGILLUS NIGER CATALASE-R)
01/01/2003CN1097632C A mutant E. coli strain with increased succinic acid production
12/2002
12/31/2002US6501008 For modifying levels of this enzyme in plants; transgenic plants; use enhancing silage or forage crop digestibility, altering plant cell wall and improving kernel growth rates
12/31/2002US6501005 DNA sequences which lead to the formation of polyfructans (levans), plasmids containing these sequences as well as a process for preparing transgenic plants
12/31/2002US6501004 Transgenic reduction of sinapine in crucifera
12/31/2002US6500959 Pyrrolidine derivatives and processes for preparing same
12/31/2002US6500945 Nucleotides having chiral phosphorus linkages
12/31/2002US6500943 Promoter
12/31/2002US6500933 Methods of preparing carbohydrate crosslinked glycoprotein crystals
12/31/2002US6500924 Package for using antagonists of the vitronectin receptor alpha-v beta3 comprising a metalloproteinase polypeptide of given amino acid sequence; treating arthritis, rheumatoid arthritis, retinopathy and tumors
12/31/2002US6500923 Isolated polypeptide that binds to an autoantibody from a dermatomyositis patient to provide means by which dermatomyositis can be detected by way of differential diagnosis
12/31/2002US6500803 Factor VIIa inhibitors
12/31/2002US6500802 Peptidyl-2-amino-1-hydroxyalkanesulfonic acid cysteine protease inhibitors
12/31/2002US6500670 Changing the oil or biopolymer content of a plant or plant storage organ by introducing an anti-sense or sense construct into a plant resulting in an inactivated pdk gene
12/31/2002US6500667 Reducing cellular production of amyloid beta from amyloid precursor protein, transforming or transfecting cells in vitro with an anti-sense reagent capable of reducing asp2 polypeptide by reducing asp2 transcription or translation
12/31/2002US6500661 Enzymatic synthesis of gdp-fucose, which can be used in fucosylation reactions; the reaction mixture comprising gdp-4-keto-6-deoxymannose, nadph, and a prokaryotic enzyme with epimerase and reductase activity
12/31/2002US6500660 Chimeric target molecule having an activity which can be regulated or modulated by a binding molecule; methods of using the chimeric target molecule to detect the presence and/or amount of a desired analyte in a sample
12/31/2002US6500659 A thermostable enzyme that catalyzes the removal of arginine, phenylalanine, or methionine from the n-terminal end of peptides
12/31/2002US6500657 33167, a novel human hydrolase and uses therefor
12/31/2002US6500656 Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
12/31/2002US6500655 Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
12/31/2002US6500654 Cardiac-related ankyrin-repeat protein kinase
12/31/2002US6500653 Nucleic acids and polypeptides which resemble RHO and which interact with cell signaling pathways and proteins
12/31/2002US6500650 Method for identifying polymorphisms
12/31/2002US6500649 Process for the conversion of organic materials, particularly saccharide materials, comprising an enzymatic oxidation step in the presence of ruthenium or palladium
12/31/2002US6500646 Drugs in which peptides having affinity specific for phospholipids, preferably those which are contained in the constituents of lipid bilayers forming the surface layers of cells and of which the proportion in the outer part of each
12/31/2002US6500639 DNA shuffling to produce nucleic acids for mycotoxin detoxification
12/31/2002US6500632 Assay for screening inhibitors of C4 plant enzymes
12/31/2002US6500628 Method for identifying a test compound which binds to a kinase comprising: contacting the kinase encoded by the nucleotide sequence shown in seq id no:1 with a test compound such that binding occurs; and detecting binding of the test compound to
12/31/2002US6500611 Inviable virus particles as scaffolds for constructing flexible detection systems
12/31/2002US6500610 Administering compounds that exhibit phosphodiesterase and cyclooxygenase inhibitory activity and apoptosis induction but prefereably not prostaglandin inhibitory activity on cultured tumor cells
12/31/2002US6500463 Mixing plasticizable matrix material, liquid plasticizer, encapsulant, non-plasticizable non-gelatinized starch, and component for controlling rate of release of encapsulant under low shear and low temperature, forming into pieces, drying
12/31/2002US6500426 Carbohydrate-based enzyme-containing granules for use in animal feed
12/31/2002US6500211 Hybrid hydrolase enzymes
12/31/2002CA2266497C Liquid detergents containing proteolytic enzyme and protease inhibitors
12/31/2002CA2245006C Protein expression system
12/31/2002CA2069460C Methods and compositions for preparation and use of a herpes protease
12/31/2002CA2022285C Enhancement of naphthalene dioxygenase activity during microbial indigo production
12/27/2002WO2002103361A1 Method for identification of agents for the treatment of diabetes