Patents for C12N 9 - Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes (141,535)
07/2003
07/31/2003WO2003061601A2 Aminophospholipid transporter atpase
07/31/2003WO2003061583A2 Digenic mutations associated with severe insulin resistance and type 2 diabetes and their use in the diagnosis and treatment of diabetes
07/31/2003WO2003061570A2 Engineered binding proteins
07/31/2003WO2003048308A3 Thermus brockianus nucleic acid polymerases
07/31/2003WO2003040381A3 Enzymatic process for the manufacture of l-ascorbic acid and d-erythorbic acid
07/31/2003WO2003037253A3 Methods for the treatment and diagnosis of tumorigenic and angiogenic disorders using 32616
07/31/2003WO2003031571A3 Novel human proteins, polynucleotides encoding them and methods of using the same
07/31/2003WO2003016338A9 Crystal structure of the btk kinase domain
07/31/2003WO2003008603A3 Process for the preparation of l-amino acids using strains of the enterobacteri acea family which contain an attenuated aspa gene
07/31/2003WO2003008602A3 Process for the preparation of l-amino acids using strains of the enterobacteriaceae family which contain an attenuated ugpb gene
07/31/2003WO2003004670A3 Process for the preparation of l-amino acids using strains of the enterobacteriaceae family with enhanced pts-g expression
07/31/2003WO2003004664A3 Process for the preparation of l-amino acids using strains of the enterobacteriaceae family with enhanced fba expression
07/31/2003WO2003004607A3 Aggrecanase molecules
07/31/2003WO2003002736A3 A walk-through technique for in vitro recombination of polynucleotide sequences
07/31/2003WO2002103032A3 Catalases, nucleic acids encoding them and methods for making and using them
07/31/2003WO2002103023A3 Method for producing c9-aldehydes, c9-alcohols by means of divinyl ether synthase
07/31/2003WO2002090571A3 Methods and compositions for modulating telomerase reverse transcriptase (tert) expression
07/31/2003WO2002090377A3 Peptides that bind to dna and inhibit dna replication, and methods of use
07/31/2003WO2002088363A3 Regulation of novel human prolyl 4-hydroxylases
07/31/2003WO2002083931A3 Method for fixing biomolecules onto chemically inert surfaces
07/31/2003WO2002081667A3 Ligases
07/31/2003WO2002068464A3 Fusion protein for blocking the hiv nef protein
07/31/2003WO2002038742A3 Dipeptidylpeptidases and methods of use
07/31/2003WO2002033041A3 Production of bovine lysozyme by plant viral vectors
07/31/2003WO2002029038A3 Novel proteins and nucleic acids encoding same and antibodies directed against these proteins
07/31/2003WO2002024747A3 Polymorphisms in human genes of cardiovascular regulators and their use in diagnostic and therapeutic applications
07/31/2003WO2002020847A3 Gene and sequence variation associated with lipid disorder
07/31/2003WO2002018548A3 Tyrosine hydroxylase 5' control elements and uses thereof
07/31/2003WO2002004489A3 Polymorphic kinase anchor proteins and nucleic acids encoding the same
07/31/2003US20030145354 Genetic engineered DNA comprising regulatory sequences of plant cell promoters linked DNA sequences that code for proteins or fragments that suppress endogenous gene expression transferase enzymes; agriculture
07/31/2003US20030145353 Polynucleotide comprising chimera genes linked to regulatory sequences that code for glycogenin, used for transforming cells and regenerating plants; genetic engineering
07/31/2003US20030145352 Nucleic acid molecules from rice and their use for the production of modified starch
07/31/2003US20030145351 Isolation of DNA sequences that code for synthase enzymes, used for screening herbicide, fungicide, bactericides and/or pesticides; genetic engineering
07/31/2003US20030145350 Method for increasing the content of fatty acids in plants and micro-organisms
07/31/2003US20030145349 Plant transcription coactivators with histone acetyl transferase activity
07/31/2003US20030145348 Dehydroquinate dehydrase/shikimate dehydrogenase as a herbicide target
07/31/2003US20030145347 Grain processing method and transgenic plants useful therein
07/31/2003US20030144497 Novel human transferase proteins and polynucleotides encoding the same
07/31/2003US20030144496 Isolated polypeptides; genetic engineering
07/31/2003US20030144495 Drosophila recombination-associated protein and methods for use
07/31/2003US20030144493 Human serine protease
07/31/2003US20030144491 Methods and materials relating to cadherin-like polypeptides and polynucleotides
07/31/2003US20030144228 PON3 and uses thereof
07/31/2003US20030144227 Pharmaceutical composition comprising Nit2 for use in inhibiting tumor cell growth
07/31/2003US20030144226 Drug screening for an antiviral agent, viricides; genetic engineering
07/31/2003US20030144205 Polynucleotide sequence encoding a polypeptide comprising an amino acid sequence that modulates protein degradation during gametogenesis and early development
07/31/2003US20030144204 Expression vector with an inducible chimeric protein, wherein said protein comprises a mutant Akt polypeptide fused to a ligand binding domain
07/31/2003US20030144180 Contains as active ingredient a therapeutically effective amount of agent for either enhancing protein kinase c production and/or activation
07/31/2003US20030144165 For use in detergents and in baking
07/31/2003US20030143740 Integrating nucleic acid into the genome of mammalian cells by forming an integrator complex between a nucleic acid containing a transposon and a transposase specific for the transposon
07/31/2003US20030143715 Glutaryl cephalosporin amidase from pseudomonas diminuta BS-203
07/31/2003US20030143714 Crystal structure of a mutant of cathepsin S enzyme
07/31/2003US20030143713 Novel glycosidase inhibitors and their pharmacological uses, in particular for treating diabetes
07/31/2003US20030143712 Nucleic acid; use identifying the enzyme inhibitors which are used as antitumor agents; detection of cells expressing the enzyme
07/31/2003US20030143711 Hydrolyses organophosphate insecticides including malathion; bioremediation
07/31/2003US20030143710 Protein corresponding to recombinant fungal epoxide hydrolase; use making enantiomerically pure diols and/or epoxides
07/31/2003US20030143703 Recombinant microorganism expressing polyhydroxyalkanoate biosynthesis enzyme and intracellular PHA depolymerase
07/31/2003US20030143700 Specific, asymmetric reduction of 3-quinuclidinone using tropinone reductase-I in the presence of a reduced coenzyme to produce (R)-3-quinuclidinol; high optical purity
07/31/2003US20030143692 Methods and compositions for modulating integrin-mediated cell-cell interactions
07/31/2003US20030143690 Peptides and proteins that effect protein phosphorylation; genetic engineered DNA; useful for therapy and diagnosis
07/31/2003US20030143688 Human skeletal muscle-specific ubiquitin-conjugating enzyme
07/31/2003US20030143686 Transferases
07/31/2003US20030143677 Activated rec-D-hydantoinases
07/31/2003US20030143675 Novel 38594, 57312, 53659, 57250, 63760, 49938, 32146, 57259, 67118, 67067, 62092, 8099, 46455, 54414, 53763, 67076, 67102, 44181, 67084FL, 67084ALT, FBH58295FL, 57255, and 57255alt molecules and uses therefor
07/31/2003US20030143674 Polypeptides fused to heterologous polypeptide sequences, and an antibodies which bind to the above polypeptides
07/31/2003US20030143669 Contacting a mammalian cell culture expressing a lysosomal hydrolase with a mutagenic agent; culturing culture in presence of pseudomonas exotoxin A to select for cell resistant to the pseudomonas, isolating lysosomal hydrolase
07/31/2003US20030143660 Genes have been isolated from Rhodococcus and Deinococcus which encode a specific lycopene beta -cyclase capable of converting acyclic carotenoids with atleast one psi-end group to corresponding asymetric caratenoid
07/31/2003US20030143657 For identification of fungicides which affect biosynthesis of l-leucine; drug screening
07/31/2003US20030143656 Drug screening compounds which inhibit rate of phosphorylation by kinase having hydrophobic pocket domain; surface plasmon resonance; fusion proteins; anticancer-/ antidiabetic agents
07/31/2003US20030143648 Enzyme activity profiles
07/31/2003US20030143632 Fusion proteins; tango genes; drug screening; competitive binding assay
07/31/2003US20030143624 Trans-prenyl-protein transferases; animal models; drug screening
07/31/2003US20030143620 Carbohydrate ligands specific for MHC molecules
07/31/2003US20030143618 PCR amplification of each part of the two parts of DNA molecule by means of two primer sets that build in a recombiantion site at the outer end of each PCR product, ligation of PCR product, recombiantion cloning of the PCR
07/31/2003US20030143617 ATP synthase subunits
07/31/2003US20030143589 Drug metabolizing enzymes
07/31/2003US20030143588 Phosphodiesterases
07/31/2003US20030143577 High fidelity DNA polymerase compositions and uses therefor
07/31/2003US20030143567 An expression vector containing a promoter operably linked to a nucleic acid that encodes a prokaryotic enzyme having both epimerase/ reductase activity catalyzes conversion of GDP-4-keto-6-deoxymannose to GDP-fucose
07/31/2003US20030143528 Vector for analayzing replication mechanism of rna virus and use thereof
07/31/2003US20030143522 Screening and use of agents which block or activate intein splicing utilizing natural or homologous exteins
07/31/2003US20030143244 For preparation of D-amino acids starting from 5'-substituted hydantoins
07/31/2003US20030143240 Prostase protein vaccine comprising derivatised thiol residues and methods for producing said antigen
07/31/2003US20030143228 Human telomerase reverse transcriptase as a class-II restricted tumor-associated antigen
07/31/2003US20030143219 Therapy and prophylaxis of neoplastic disease, in a mammal
07/31/2003US20030143216 For therapy of fungal infections; for detecting chitin, binding chitin
07/31/2003US20030143209 For gene therapy of cancers or cardiovascular conditions
07/31/2003US20030143208 For therapy of neurodegenerative disorders associated with oxidative damage and subsequent neuronal cell loss, including, but not limited to, Parkinson's disease and head trauma
07/31/2003US20030143206 Increasing the level of at least one isoform of the enzyme nitric oxide synthase in the cells of the ano-rectal region for therapy of anal disease
07/31/2003US20030143198 Method for preparing a physiologically active il-18 polypeptide
07/31/2003CA2829859A1 Multiply-substituted protease variants
07/31/2003CA2732012A1 Genetic sequences having methyltransferase activity and uses therefor
07/31/2003CA2474033A1 Fermentation of pentose sugars
07/31/2003CA2473716A1 Alanine 2,3- aminomutase
07/31/2003CA2473032A1 Novel peptides as ns3-serine protease inhibitors of hepatitis c virus
07/31/2003CA2472775A1 Synthetic peptides and uses thereof for the prevention and therapy of cancer invasion and metastasis
07/31/2003CA2472729A1 Nuclear-envelope and nuclear-lamina binding chimeras for modulating gene expression
07/31/2003CA2472725A1 Multiply-substituted protease variants
07/31/2003CA2472723A1 Multiply-substituted protease variants
07/31/2003CA2454358A1 Multimeric proteins and methods of making and using same