Patents for C12N 9 - Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes (141,535)
10/2003
10/02/2003US20030186866 Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis
10/02/2003US20030186859 58224, a novel helicase family member and uses therefor
10/02/2003US20030186850 Administering an effective amount of an appropriate agent which is effective in modulating functions of one or more polypeptide GalNAc-transferases (N-acetylgalactosaminyltransferases)
10/02/2003US20030186840 Regulation of human l-asparaginase-like enzyme
10/02/2003US20030186837 Contacting Asparagine Synthase polypeptide with test compound; detecting presence or absence of binding between test compound and Asparagine Synthase polypeptide, wherein binding indicates that test compound is candidate for antibiotic
10/02/2003US20030186443 Phytase active yeast
10/02/2003US20030186438 Premature osteoblast cell line derived from the peritoneum of bone for use as models for prevention and treatment of osteoporosis
10/02/2003US20030186435 Comprises antagonist that inhibits activity or expression oxidoreductase (FABH) for treating bacterial infection; bactericides
10/02/2003US20030186423 Amidase from variovorax
10/02/2003US20030186422 Methods for the treatment of thrombosis
10/02/2003US20030186421 Comprises lipoprotein associated phospholipase A2 (Lp-PLA2) for diagnosing and treating atherosclerosis; enzyme inhibitors
10/02/2003US20030186420 Prolidase and its gene and method for producing prolidase
10/02/2003US20030186419 Masp-3, a complement-fixing enzyme, and uses for it
10/02/2003US20030186418 Novel variant EGIII-like cellulase compositions
10/02/2003US20030186417 Polypeptides and/or peptide sequences associated with pectin esterase (PME) for use as substituents of food stuffs; food processing
10/02/2003US20030186416 Coding sequence for protein phosphatase methylesterase, recombinant DNA molecules and methods
10/02/2003US20030186415 Mutant possessing uracil phosphoribosyl transferase activity
10/02/2003US20030186414 Nucleotide sequences coding chimeric enzymatic polypetide for biosynthesis of oligosaccharides
10/02/2003US20030186412 Polypeptides which asymmetrically reduce N-benzyl-3-pyrrolidinone to produce (S)-N-benzyl-3-pyrrolidinol with NADPH as coenzyme
10/02/2003US20030186411 Cytochrome P450 monooxygenase and NADPH cytochrome P450 oxidoreductase genes and proteins related to the omega hydroxylase complex of Candida tropicalis and methods relating thereto
10/02/2003US20030186410 Comprises enzymatic protein which reduces phenylpyruvic acid and produces phenyllactic acid; hypotensive agents
10/02/2003US20030186409 Extracting enzyme inhibitors from wheat flour or gluten for treating hyperglycemia, diabetes, hyperlipemia and arteriosclerosis
10/02/2003US20030186408 Secreted and transmembrane polypeptides and nucleic acids encoding the same
10/02/2003US20030186407 Comprises membrane protein for use as antitumor/antiproliferative/antiinflammatory/anticarcinogenic agents
10/02/2003US20030186402 Engineering fungi for the utilisation of l-arabinose
10/02/2003US20030186400 Method for producing optically active 2-hydroxycycloalkanecarboxylic acid ester
10/02/2003US20030186389 For degradation by fucoidan deacetylases, glucuronidases, and fucosidases
10/02/2003US20030186384 Comprises enzyme complex formed from proteases for modulating apoptosis and treating tumor, allergenic, autoimmune diseases and inflammatory diseases
10/02/2003US20030186380 Methods for producing secreted polypeptides having L-asparaginase activity
10/02/2003US20030186378 Useful mutations of bacterial alkaline protease
10/02/2003US20030186367 Secreted and transmembrane polypeptides and nucleic acids encoding the same
10/02/2003US20030186366 For stimulating release of tumor necrosis factor and/or cellular differentiation of chondrocytes, endothelial cells or adipocytes by contacting blood with pro-polypeptide; cancer diagnosis and treatment
10/02/2003US20030186363 Method for cloning and expression of BsaI restriction endonuclease and BsaI methylase in E. coli
10/02/2003US20030186358 Comprise nucleotide sequences coding membrane protein for use as antitumor, antiproliferative, anticarcinogenic or antiinflammatory agents
10/02/2003US20030186356 Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
10/02/2003US20030186354 Mutated penicillin expandase and process for preparing 7- ADCA using the same
10/02/2003US20030186352 Apicomplexan chorismate synthase sequences and an inhibitor of the shikimate pathway
10/02/2003US20030186319 Comprises nucleotide sequences coding membrane protein for use as antiinflammatory/antitumor/anticarcinogenic/ antiproliferative agents
10/02/2003US20030186318 Comprises nucleotide sequences coding membrane protein for use as antiinflammatory/antitumor/anticarcinogenic/ antiproliferative agents
10/02/2003US20030186317 Identifying modulators of calcium-binding protein (CIB)/mixed lineage kinase 2 (MLK2) complexes for treatment and prevention of nervous system disorders
10/02/2003US20030186306 Nucleotide sequences coding interleukins for treating tumors, bone, nervous system, neovascularization and autoimmune disorders
10/02/2003US20030186305 Novel proteins
10/02/2003US20030186291 Comprises nucleotide sequences coding recombinase for use as insertional tool in gene therapy
10/02/2003US20030186284 Method of screening ptp ç activitiy promoter or inhibitor
10/02/2003US20030186282 Using purified telomerase to identify telomerase activators and inhibitors
10/02/2003US20030186270 Compositions and methods for reverse transcription of nucleic acid molecules
10/02/2003US20030186264 Comprises enzymatic polypeptide for diagnosis and treatment of genetic disorders; drug screening; immunoassay; high throughput assay
10/02/2003US20030186258 Comprises protease (KEX1) for processing fusion proteins containing peptides or proteins of industrial and/or therapeutic interest; biocatalysts
10/02/2003US20030186254 Comprises nucleotide sequences coding serine/threonine kinase (PAK4) which effects guanyl-nucleotide exchange factor (GEF) activity for diagnosis and treatment of viral diseases
10/02/2003US20030186238 RNA detection assays
10/02/2003US20030186233 Nucleotide sequences coding topoisomerase binding sites for use in vector for concurrent recombinational cloning of two or more DNA sequences
10/02/2003US20030186231 Systematic evolution of ligands by exponential enrichment: Chemi-ESLEX
10/02/2003US20030185858 Engineered for both enhanced stability of self-assembled particles and the display of an immunogenic epitope.
10/02/2003US20030185846 Secreted and transmembrane polypeptides and nucleic acids encoding the same
10/02/2003US20030185830 Compositions and methods for the therapy and diagnosis of prostate cancer
10/02/2003US20030185828 For treating osteoarthritis
10/02/2003US20030185814 Ceramidase
10/02/2003CA2517582A1 Saccharomyces cerevisiae yeast strain with improved phytase activity
10/02/2003CA2481556A1 Modified plasminogen activator inhibitor type-1 and methods based thereon
10/02/2003CA2479858A1 Methods and compositions for using zinc finger endonucleases to enhance homologous recombination
10/02/2003CA2479719A1 Novel compositions and methods in cancer associated with altered expression of mcm3ap
10/02/2003CA2479587A1 Nucleic acid constructs and methods for producing altered seed oil compositions
10/01/2003EP1348761A1 Marburg I mutant of factor VII activating protease (FSAP) as a risk factor for arterial thrombosis
10/01/2003EP1348760A2 Production of inactive mutants or mutants with a low activity of an alkaline phosphatase and their expression in yeast
10/01/2003EP1348759A1 Mutated penicillin expandase and process for preparing 7-ADCA using the same
10/01/2003EP1348028A2 Substrate linked directed evolution (slide)
10/01/2003EP1348023A2 53010, a human carboxylesterase family member and uses thereof
10/01/2003EP1348022A2 Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
10/01/2003EP1348021A2 25206, a novel human short-chain dehydrogenase/reductase family member and uses thereof
10/01/2003EP1347767A1 Tahitian noni juice on cox-1 and cox-2 and tahitian noni juice as a selective cox-2 inhibitor
10/01/2003EP1019434B1 Inhibitors of metalloproteinases, their therapeutic use, and process for the production of the starting compound in their synthesis
10/01/2003EP0935755B1 Method for determining an increased chance of mortality
10/01/2003EP0846759B1 Gene encoding protein having asymmetric hydrolase activity on 4-substituted-1,4-dihydropyridine derivatives and expression product of the same
10/01/2003EP0662087B1 Method for purifying retinal pigmented epithelium derived neurotrophic factor
10/01/2003EP0656940B1 Genetic sequences encoding glycosyltransferase enzymes and uses therefor
10/01/2003EP0594678B1 Production of polyalkanoate
10/01/2003CN1446260A Lipoxygenase genes, promoters, transit peptides and protein thereof
10/01/2003CN1446257A Preparation of dicarboxylic acid monoesters from cyanocarboxylic acid esters
10/01/2003CN1446201A Novel peptides as NS3-serine protease inhibitors of hepatitis C virus
10/01/2003CN1445369A Technique of preparing and purifying antigen for testing primary biliary cirrhosis
10/01/2003CN1445366A New protein kinase specific to human cardiac muscle and its coded sequence
10/01/2003CN1445365A Method for preparing algin lyase and its application
10/01/2003CN1445364A Live scorpion enzyme and its preparing method
10/01/2003CN1445362A Method for increasing yield of superoxide dismutase of radioresistant coccus by radiation induction
10/01/2003CN1122718C Botulinum toxin derivatives able to modify peripheral sensory afferent functions
10/01/2003CN1122717C Cyclodextrin glycosyltransferases for producing ganame cyclodextrin
09/2003
09/30/2003US6627799 Genetic engineered cells having ability to adjust to environment and have plant disease resistance; hybrids
09/30/2003US6627798 Nucleotide sequences coding polypeptide associated with tyrosine biosynthesis for use in generation of amplified tyrosine concentration in plants
09/30/2003US6627795 DNA and/or complements comprising nucleotide sequences that code for polypeptides having lyase enzyme activity; genetic engineering
09/30/2003US6627794 Polyphenyl oxidase genes from banana
09/30/2003US6627739 Antibodies having preferential binding to proteases; screening for enzyme inhibitors used in therapy of neurodegenerative diseases, such as Alzheimer's disease
09/30/2003US6627737 Factor IX purification methods
09/30/2003US6627735 Islet cell antigen 1851
09/30/2003US6627731 Thrombin derived polypeptides; compositions and methods for use
09/30/2003US6627619 Cancer diagnosis
09/30/2003US6627605 Polynucleotides which encode them, and methods for their use. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention further provides methods for diagnosing or treating disorders with
09/30/2003US6627429 Using a methyl esterase; deesterification; allows proteins to be stable in acidic solutions; useful in preparation of foodstuff
09/30/2003US6627425 Human glucose-6-phosphatase molecules and uses thereof
09/30/2003US6627424 Protein comprising a sequence non-specific binding domain and a DNA polymerase domain; enhances binding and catalytic activity
09/30/2003US6627423 Genetic engineering