Patents for C12N 9 - Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes (141,535)
12/2004
12/16/2004WO2004108937A1 Cell surface expression vector of sars virus antigen and microorganisms transformed thereby
12/16/2004WO2004108932A1 Bacteria with increased levels of protein secretion, nucleotide sequences coding for a seca protein with increased levels of protein secretion, and method for producing proteins
12/16/2004WO2004108917A1 Method for stabilization of enzymes during exposure to sterilizing radation
12/16/2004WO2004108916A1 Methods and compositions for diagnosing and treating disorders involving angiogenesis
12/16/2004WO2004108915A1 Fusion protein containing a dimerisation domain and an autotransporter domain
12/16/2004WO2004108914A1 Sars coronaviruses 3cl protease 3d-structure model and anti-sars medicines
12/16/2004WO2004108913A1 Process for producing phosphorylase
12/16/2004WO2004108912A2 Phosphite dehydrogenase mutants for nicotinamide cofactor regeneration
12/16/2004WO2004108911A2 Method for production of enzyme granules and enzyme granules produced thus
12/16/2004WO2004108906A2 Bacterial carriers for nucleotide sequences coding for active substances
12/16/2004WO2004108904A2 Porcine cmp-n-acetylneuraminic acid hydroxylase gene
12/16/2004WO2004108894A2 Methods and compositions for amino acid production
12/16/2004WO2004108765A2 Extracellular aspergillus polypeptides
12/16/2004WO2004108763A2 Mutants of the factor vii epidermal growth factor domain
12/16/2004WO2004108762A1 Immobilized membrane proteins and methods of use therefor
12/16/2004WO2004108754A2 Herpes simplex virus us11 protein and hipk2 protein complexes and uses thereof
12/16/2004WO2004108176A1 Skin dressings containing oxidoreductase enzyme
12/16/2004WO2004108071A2 Targeting polypeptides to the central nervous system
12/16/2004WO2004108069A2 Compositions and methods for promoting neuronal outgrowth
12/16/2004WO2004099400A3 Variant lipolytic ensymes
12/16/2004WO2004093532A3 Generation of plants with altered oil content
12/16/2004WO2004087960A3 Method and system for rapidly conferring a desired trait to an organism
12/16/2004WO2004081165A3 Novel purified dihydrodipicolinate synthase polypeptides and structures thereof
12/16/2004WO2004080923A3 Alcohol product processes
12/16/2004WO2004076659A3 Method for the production of evolved microorganisms which permit the generation or modification of metabolic pathways
12/16/2004WO2004074443A3 Glyphosate resistant class i 5-enolpyruvylshikimate-3-phosphate synthase (epsps)
12/16/2004WO2004067738A3 Nitrile hydratases from rhodococcus erythropolis and their application
12/16/2004WO2004046336A3 Production of increased oil and protein in plants by the disruption of the phenylpropanoid pathway
12/16/2004WO2004029253A3 Nucleic acid sequences coding for proteolytic enzymes in the form of specific proteases, corresponding polypeptides and use of the same
12/16/2004WO2004022697A3 Denaturat stable and/or protease resistant, chaperone-like oligomeric proteins, polynucleotides encoding same, their uses and methods of increasing a specific activity thereof
12/16/2004WO2004016646A3 Peptide modulators of tumour specific pyruvate kinase subtype m2 (m2-pk)
12/16/2004WO2003082909A8 Non-ribosomal peptide synthetases and associated biosynthetic genes
12/16/2004WO2003080809A3 Methods and compositions for using zinc finger endonucleases to enhance homologous recombination
12/16/2004WO2003068932A3 Method for crystallizing human gsk3 and novel crystal structure thereof
12/16/2004WO2003059268A3 A novel germ cell-specific contraceptive target
12/16/2004WO2003054184A9 Novel alkali protease formed by bacillus gibsonii (dsm 14393) and washing and cleaning agents containing said novel alkali protease
12/16/2004WO2003050245A3 Therapeutic polypeptides, nucleic acids encoding same, and methods of use
12/16/2004WO2003016485A3 Full-length serine protein kinase in brain and pancreas
12/16/2004WO2003005953A3 Viral proteins capable of binding lar
12/16/2004US20040255343 Caspase-9 deficient animals and the use thereof
12/16/2004US20040254774 Model for mutually exclusive domain folding molecular switch
12/16/2004US20040254359 Antisense modulation of stearoyl-coa desaturase expression
12/16/2004US20040254358 Phosphorous-linked oligomeric compounds and their use in gene modulation
12/16/2004US20040254350 Immunomodulatory protein for use in diagnosis, treatment, and prevention of immune system, neurological, developmental, muscle and cell proliferative disorders
12/16/2004US20040254349 Mycobacterial antigens expressed under low oxygen tension
12/16/2004US20040254347 Immobilizing tetrapeptide to solid support via exposure to transglutaminase for use as tool in enhancing immune response; immunotherapy
12/16/2004US20040254177 Aminoindazole derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions containing them
12/16/2004US20040254140 Method for selective inactivation of viral replication
12/16/2004US20040254135 Administering enzyme inhibitor; moderate metabolism
12/16/2004US20040254116 Contactor tissue with transforming growth factor kinase receptors; modulate cell proliferation
12/16/2004US20040254115 Compositions and methods for promoting internalization and degradation of urokinase-type plasminogen activator
12/16/2004US20040254106 Modified factor ix
12/16/2004US20040254087 Core of active material with wax coating
12/16/2004US20040254083 Method for selective oxidation of substituted toluenes by microbial coprinus peroxidases
12/16/2004US20040253723 Modulation of growth hormone receptor expression and insulin-like growth factor expression
12/16/2004US20040253713 Ethanol production
12/16/2004US20040253711 Mycobacterial genes down-regulated during latency
12/16/2004US20040253707 Novel cathepsins L-like cysteine protease derived from northern shrimp (Pandalus eous)
12/16/2004US20040253705 Isolated human protease proteins, nucleic acid molecules encoding human protease proteins, and uses thereof
12/16/2004US20040253704 Plasmid comprising nucleotide sequences coding poly- gamma -glutamate synthetase for use in developing vaccine for prevention and treatment of bacillus infection
12/16/2004US20040253703 Novel aminopeptidase derived from bacilius licheniformis, gene encoding the aminopeptidase, expression vector containing the gene, transformant and method for preparation thereof
12/16/2004US20040253702 Variants of beta-glucosidases
12/16/2004US20040253701 Protein and peptide fragments from mouse telomerase reverse transcriptase
12/16/2004US20040253700 Expression vector comprising nucleotide sequences coding adenosine triphosphatase for use in improving organismal energy metabolism
12/16/2004US20040253699 Insect inhibitory lipid acyl hydrolases
12/16/2004US20040253698 Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
12/16/2004US20040253697 Nucleotide sequences coding epothilone polyketide synthase for use in generating fungicides, immunosuppressants and/or antitumor agents in microorganisms; bioreactors and heterologous gene expression
12/16/2004US20040253695 Using enone reductase to generate optically active intermediates for use in the synthesis of pharmaceuticals
12/16/2004US20040253694 Preparing nutrient broth comprising tannin-rich mixed substrate, adding innoculum comprising rhizopus oryzae and aspergillus, ferment, use organic acid to extract gallic acid; bioreactors
12/16/2004US20040253693 Methods for the biosynthesis of polyesters
12/16/2004US20040253685 eNOS mutations useful for gene therapy and therapeutic screening
12/16/2004US20040253681 Mitogenic oxygenase regulators
12/16/2004US20040253680 Propagating in transgenic escherichia for use in preparing cheese from cheese milk; food processing
12/16/2004US20040253676 Method for producing sweetners and alcohol
12/16/2004US20040253670 Using eschericia as bioreator for production of pasturella galactosyltransferase for use in processing sugars for use as components of pharmeceuticals
12/16/2004US20040253669 Regulation of human dcamkl1-like serine/threonine protein kinase
12/16/2004US20040253667 Expression vector comprising nuclelotide sequences coding membrane protein for use in identifying modulator for treatment of cell proliferative, nervous system and inflammatory diseases
12/16/2004US20040253666 Secreted and transmembrane polypeptides and nucleic acids encoding the same
12/16/2004US20040253665 Novel peptide-producing enzyme, microbe producing the enzyme and method for dipeptide synthesis using them
12/16/2004US20040253663 Genes encoding carotenoid compounds
12/16/2004US20040253631 Expression vector comprising topisomerase site-specific recombination sequences for use as gene transfer and propagation tools in bioreactors; gene therapy; protein and gene expression analysis
12/16/2004US20040253628 Using modified grampositive bacteria as bioreactors for fermentation of lysine; for use in medicine, cosmetics and animal feeds
12/16/2004US20040253621 Codon-optimized genes for the production of polyunsaturated fatty acids in oleaginous yeasts
12/16/2004US20040253605 Expression vector comprising nucleotide sequences coding aggrecanase for use in diagnosis, prevention and treatment of cell proliferative disorders
12/16/2004US20040253588 Cytochrome p450 monooxygenase for use in identifying modulators for treatment, diagnosis and prevention of autoimmune/inflammatory, cell proliferative, developmental, endocrine, eye, metabolic, gastrointestinal and liver disorders
12/16/2004US20040253577 Polypeptide comprising helicase activity for use as tool in design of drugs for treatment and prevention of viral infection; viricides
12/16/2004US20040253345 Method for preparing calcium gluconate
12/16/2004US20040253245 Modulating an immune response by administering a modulator of Notch intracellular domain protease activity, including modulators of presenilin and presenilin-dependent gamma secretase activity; immunotherapy; treatment of Alzheimer's disease
12/16/2004US20040253226 administering to the animals angiogenesis inhibitors comprising kallikreins such as prostate specific antigens (PSA), hydrolase enzymes homologs or fragments; prophylaxis of cancer, arthritis and vision defects
12/16/2004US20040253224 genetically engineered hydrolase enzymes comprising amino acid sequence having chitinase activity, used for treating respiratory system disorders such as cystic fibrosis, chronic obstructive pulmonary disease, asthma, bronchitis or tuberculosis
12/16/2004US20040253221 Novel pla1
12/16/2004US20040253220 amino acid sequences of human oxidoreductase enzymes, used for activating expression of elastin; cosmetics
12/16/2004US20040253178 Crystals and structures of spleen tyrosine kinase SYKKD
12/16/2004US20040251145 High throughput screening (HTS) method and apparatus for monitoring ion channels
12/16/2004CA2529063A1 Phosphite dehydrogenase mutants for nicotinamide cofactor regeneration
12/16/2004CA2528851A1 Extracellular aspergillus polypeptides
12/16/2004CA2528500A1 Porcine cmp-n-acetylneuraminic acid hydroxylase gene
12/16/2004CA2528239A1 Mutants of the factor vii epidermal growth factor domain
12/16/2004CA2527346A1 Cell surface expression vector of sars virus antigen and microorganisms transformed thereby
12/16/2004CA2527318A1 Methods and compositions for diagnosing and treating disorders involving angiogenesis