Patents for C12N 9 - Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes (141,535)
10/2008
10/28/2008US7442681 regulating vascular permeability. A peptide inhibitor of p21-activated kinase has been found to inhibit the increase in vascular permeability induced by several factors. The present invention further provides methods of identifying regulators of vascular permeability.
10/28/2008US7442537 Crystals of unliganded beta secretase and/or beta secretase-like proteins and the use thereof
10/28/2008US7442536 proteins is "cysteinized" to permit easier conjugation to a targeting moiety
10/28/2008US7442535 Fusion protein incorporating a cysteinized ribonuclease
10/28/2008US7442534 Nucleic acids and polypeptides which resemble Rho and which interact with cell signalling pathways and proteins
10/28/2008US7442533 Nematode phosphoethanolamine N-methyltransferase-like sequences
10/28/2008US7442532 Essential fungal CaYLR100w polypeptides, and methods of use
10/28/2008US7442526 co-expressing bicistronically caspase 4 with the human precursor IL-18 polypeptide and purifying the active polypeptide
10/28/2008US7442524 Conjugate comprising polypeptide with N-glycosylation site and sugar; increase blood clot formation for treatment of thrombocytopenia and hemophilia
10/28/2008US7442514 Mutants of the factor VII-activating protease and detection methods using specific antibodies
10/28/2008US7442513 Method of screening for agents that modulate a homer signaling pathway
10/28/2008US7442501 Associated with connective tissue diseases, progeroid disorders, and aging; methods for isolating such molecules; and the use of such molecules in human and veterinary practice
10/28/2008US7442398 Phytase produced from Citrobacter braakii
10/28/2008US7442372 Intrathecal administering of genetic engineered enzyme such as iduronidase; reduced storage of mucopolysaccharides
10/28/2008CA2400585C Hydroperoxide lyase regulatory region
10/28/2008CA2252616C Biocatalysts with amine acylase activity
10/28/2008CA2236948C Modified proteins and methods of their production
10/27/2008CA2586748A1 Agents for prophylaxis or treatment of neurological diseases and conditions
10/27/2008CA2585247A1 Agents for prophylaxis or treatment of neurological related diseases and conditions
10/23/2008WO2008128241A1 Delta 9 elongases and their use in making polyunsaturated fatty acids
10/23/2008WO2008128240A1 Delta 9 elongases and their use in making polyunsaturated fatty acids
10/23/2008WO2008128161A2 Identification of cardiac specific myosin light chain kinase
10/23/2008WO2008128050A2 Methods for identification of modulators of carm1 methyl transferase activity
10/23/2008WO2008127702A2 Modified factor vii polypetides and uses thereof
10/23/2008WO2008127240A1 Compositions and methods of producing methionine
10/23/2008WO2008126401A1 Apparatus for refolding protein
10/23/2008WO2008126400A1 Column packing and column for refolding protein
10/23/2008WO2008125685A2 Whey protein hydrolysate
10/23/2008WO2008125623A2 Molecules and methods for modulating proprotein convertase subtilisin/kexin type 9 (pcsk9)
10/23/2008WO2008125080A2 Protein for chemoenzymatic production of l-threo-hydroxyaspartate
10/23/2008WO2008084470A3 Immobilized interfacial enzymes of improved and stabilized activity
10/23/2008WO2008066707A3 Targeting prohormone convertase enzymes to suppress pomc-msh processing to induce skin lightening
10/23/2008WO2008064314A3 Recombinant yeast strains expressing tethered cellulase enzymes
10/23/2008WO2008036863A3 Phospholipases, nucleic acids encoding them and methods for making and using them
10/23/2008WO2008030995A3 Use of novel pepc to produce succinate
10/23/2008WO2008008814A3 Tissue transplantation compositions and methods
10/23/2008WO2007130886A3 Nutritional supplement and use thereof
10/23/2008WO2007127735A3 Prokaryotic host cells for expressing proteins rich in disulfide bonds
10/23/2008WO2007066779A9 Novel lipase
10/23/2008WO2005121352A3 Carotenoid ketolase genes with improved ketocarotenoid yield
10/23/2008US20080263728 Plastidial targeting peptide
10/23/2008US20080263725 expression of the nucleic acid sequence in the plant results in increased tolerance to environmental stress (drought, cold, oxidation)
10/23/2008US20080263689 Screening/monitoring rate of internalization of insulin receptors in insulin-stimulated hepatocytes; identifying modulators of insulin clearance and secretion; treating insulin resistance
10/23/2008US20080263688 Hafnia Phytase
10/23/2008US20080263683 Animal models expression receptors for advanced glycation end-products (RAGE) and inducible nitric oxide synthase for use as tool in identifying modulators for treatment and prevention of glomerular disorders
10/23/2008US20080262211 Hepatitis-c virus type 4, 5 and 6
10/23/2008US20080262205 Unphosphorylated glycogen synthase kinase-3-g-beta (GSK) from baculovirus overexpression system; competitive binding; diabetes, Alzheimer's disease
10/23/2008US20080262201 Method and a system for predicting protein functional site, a method for improving protein function, and a function-modified protein
10/23/2008US20080262166 Controlling hydrolysis stability of polymer; reacting polyether with n,n'-dicyclohexylcarbodiimide
10/23/2008US20080261903 Isolated polynucleotide encoding a Regulated in chronic obstructive pulmonary disease Kinase polypeptide; host cell; hybridization; screening; prediction, diagnosis; prognosis; chronic obstructive pulmonary disease, asthma, cancer, diseases of defective cell signaling
10/23/2008US20080261877 Albumin Fusion Proteins
10/23/2008US20080261833 Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
10/23/2008US20080261318 Signalling Compounds For Use In Methods Of Detecting Hydrogen Peroxide
10/23/2008US20080261311 Translation systems with orthogonal aminoacyl tRNA synthetase; membrane proteins
10/23/2008US20080261301 Mammalian cell demonstrating GDP-mannose 4,6-dehydratase (GMD) suppression and which expresses immunoglobulin associated with antibody-dependent cellular cytotoxicity; targeted treatment of tumors
10/23/2008US20080261286 Methods for producing optically active alpha-hydroxy amides
10/23/2008US20080261281 Capable of asymmetrically reducing (3S)-1-chloro-3-tert-butoxycarbonylamino-4-phenyl-2-butanone to produce (2R,3S)-1-chloro-3-tert-butoxycarbonylamino-4-phenyl-2-butanol, isolated from Ogataea
10/23/2008US20080261277 Circularly permuted RNA molecule carrying a stabilized biologically active RNA; antisense RNA; gene expression inhbition; ribozyme
10/23/2008US20080261275 Recovering and replicating RNA sequences from preferential tissues; organ specific RNA libraries
10/23/2008US20080261273 PROCESS FOR PRODUCING HMG-CoA REDUCTASE INHIBITORS
10/23/2008US20080261268 5-Substituted Hydantoin Racemase, Dna Encoding the Same, Recombinant Dna, Transformed Cell, and Process for Production of Optically Active N-Carbamylamino Acid or Optically Active Amino Acid
10/23/2008US20080261267 Cellulases from Rumen
10/23/2008US20080261241 Targeted ubiquitination of proteins and screening methods using a new class of ubiquitin ligase proteins
10/23/2008US20080261240 Method
10/23/2008US20080261224 PGC-1Beta, A Novel PGC-1 Homologue and Uses Therefor
10/23/2008US20080261208 For DNA sequencing
10/23/2008US20080260929 Endogenous seed oil having increased stearidonic acid content; transgenic plants, recombinant constructs, isolated polynucleotides
10/23/2008US20080260903 Phospholipase
10/23/2008US20080260754 Prevent transplant rejection; autoimmune diseases
10/23/2008US20080260752 Prevention and reduction of blood loss
10/23/2008US20080260747 Adhesion interaction protein (CD-84) specific immunoglobulin for use in the treatment of cell proliferative disorders of the blood
10/23/2008US20080260715 Precursor N-acetylgalactosamine-4 sulfatase, methods of treatment using said enzyme and methods for producing and purifying said enzyme
10/23/2008US20080260713 Neukinase, A Downstream protein of neuregulin
10/23/2008US20080260711 Detoxifizyme with Activity of Transforming Aflatoxin and the Gene Encodes Thereof
10/23/2008CA2684042A1 Use of substrates as pharmacological chaperones
10/23/2008CA2683562A1 Sirtuin based methods and compositions for treating .beta.-catenin-related conditions
10/23/2008CA2683443A1 Modified factor vii polypeptides and uses thereof
10/23/2008CA2682962A1 .delta.9 elongases and their use in making polyunsaturated fatty acids
10/23/2008CA2681428A1 Molecules and methods for modulating proprotein convertase subtilisin/kexin type 9 (pcsk9)
10/23/2008CA2679485A1 Delta-9 elongases and their use in making polyunsaturated fatty acids
10/23/2008CA2648864A1 Gene defects and mutant alk kinase in human solid tumors
10/22/2008EP1983059A2 Process for producing dipeptides
10/22/2008EP1983055A1 Albumin fusion proteins
10/22/2008EP1983054A1 Carbonic anhydrase and methods using the same
10/22/2008EP1983045A2 CGTase Variants
10/22/2008EP1982995A1 Improved recombinant staphylokinases
10/22/2008EP1982732A2 Factor VII or VIIA-like molecules
10/22/2008EP1982704A2 New molecular target of neurotoxicity
10/22/2008EP1981977A1 Production of polysialic acid containing glyconjugates using a self-priming polysialyltransferase
10/22/2008EP1981974A2 Compositions and methods for treating lysosomal storage diseases
10/22/2008EP1981973A2 Phosphopantetheinyl transferases from bacteria
10/22/2008EP1981972A1 Novel process
10/22/2008EP1981964A2 Mycobacterial seca2 mutants
10/22/2008EP1981914A2 Construction of new variants of dextransucrase dsr-s by genetic engineering
10/22/2008EP1981538A2 Metalloproteinase binding proteins
10/22/2008EP1981503A2 Novel neurological function of mpkci
10/22/2008EP1609866B1 Barley lipoxygenase- 1 gene, selection method for barley, materials for malt alcoholic beverages and method for production of malt alcoholic beverages
10/22/2008EP1408984B1 Organo-phosphorous compounds for activating gamma/delta t cells
10/22/2008EP1395419B1 Preservation of biological materials using fiber-forming techniques
10/22/2008EP1326631B2 Botulinumtoxin for treating endocrine disorders