Patents for C12N 9 - Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes (141,535)
07/1985
07/30/1985US4532208 Constitutive glucose isomerase producer
07/30/1985US4532129 Composition containing angiokinase enzyme isolated by extraction of vascular tissue for prophylaxis and treatment of abnormal fibrin and thrombus formation
07/30/1985US4532064 Aqueous enzyme-containing compositions with improved stability
07/30/1985CA1191099A1 Amylase-negative, asporogenous mutant of bacillus subtilis useful as a host in a host vector system
07/30/1985CA1191088A1 Powdery pharmaceutical composition of myeloperoxidase
07/24/1985EP0149578A2 Xanthine derivatives, processes for their preparation and pharmaceutical compositions containing them
07/24/1985EP0149520A2 Modified lipase
07/24/1985EP0149499A2 Novel delta4- and delta5- androstene derivatives, processes for their preparation and pharmaceutical compositions containing these derivatives
07/24/1985EP0149468A2 Biologically active substance with hormonal characteristics, process for its preparation and use of histons for medicinal ends
07/24/1985EP0149241A2 DNA base sequence containing regions involved in the production and secretion of a protein, recombinant DNA including the whole or a part of the DNA base sequence, and method of producing proteins by use of the recombinant DNA
07/24/1985EP0148950A1 Process for preparing bilirubin oxidase
07/24/1985EP0148845A1 Cloning vector, method of constructing such, and method of concentrating and purifying product proteins produced by the cloning vector
07/23/1985US4530906 Acylating microbial rennet with succinic anhydride
07/23/1985US4530903 Converting an hydroxycarboxylic acid to ketocarboxylic acid
07/18/1985WO1985003003A1 Biologically active substance with hormonal properties, production process thereof and utilization of histones for medical purposes
07/17/1985EP0148752A2 Protease inhibitors
07/17/1985EP0148668A2 Plasmid cloning and expression vectors for a protein in a microorganism, comprising at least the expression promotor of beta-glucosidase in the yeasts; these vectors containing microorganisms; fermentation process and enzymes so obtained
07/17/1985EP0148552A1 Streptomyces expression sequence and methods for expressing DNA sequences in streptomyces
07/16/1985US4529697 Process for producing L-glutamic acid by fermentation
07/16/1985CA1190495A1 Process for purifying elastase
07/10/1985EP0147805A2 Spiro-linked pyrrolidine-2,5-diones and process for their preparation
07/09/1985US4528397 Aminocarboxylic acid derivatives
07/09/1985US4528135 Process for the preparation of penicillanic acid 1,1-dioxides
07/03/1985EP0147198A2 Fermentation processes and their products
07/03/1985EP0147178A2 Expression plasmids for improved production of heterologous protein in bacteria
07/03/1985EP0147121A1 2,6-Dioxopiperidine derivatives, their preparation and pharmaceutical compositions containing them
07/03/1985EP0146871A2 Purification of flavin adenine dinucleotide synthetase
07/03/1985EP0146785A1 Process for the preparation of protease inhibitors
07/02/1985US4526868 Enzymes extracted from whole stomachs of seals
07/02/1985US4526866 Polypeptide composed of seventeen amino acid residue structural units having no inhibitory effect on thermolycin, pepsin, and alpha chymotrypsin
07/02/1985US4526783 Antibiotic from S. clavuligerus
07/02/1985CA1189807A1 Microbiological process for oxidation of alkanes, vinyl compounds and secondary alcohols
07/02/1985CA1189788A1 Method of producing a tissue plasminogen activator and composition comprising same
06/1985
06/26/1985EP0146523A2 Moraxella bovis bacterin
06/26/1985EP0146050A2 Site selective plasminogen activator and method of making and using same
06/26/1985EP0146022A2 Recovery of acid fungal protease
06/26/1985EP0145798A1 Bacillus subtilis DSM 2704 and process for the preparation of alpha-amylase
06/25/1985US4525465 Water-insoluble biospecific absorbent containing argininal derivative
06/25/1985US4525458 Method for the production of sphingomyelinase
06/25/1985US4525455 Method for preparing a cell free homogenate of Chrysanthemum cinerariaefolium (Trev.) Bocc. containing enzymes and methods of use
06/25/1985US4525454 Production of L-4-phenyl-2-aminobutanoic acid by transamination
06/25/1985US4525352 Antibiotics
06/25/1985CA1189468A1 Process for producing 3'-deoxyguanosine
06/20/1985WO1985002618A1 2,6-dioxopiperidine derivatives, their preparation and pharmaceutical compositions containing them
06/19/1985EP0145092A2 Process for the preparation of a germ-free solution of a lactose-splitting enzyme and its use
06/19/1985EP0144951A2 N-2,3-butadienyl-1,4-butanediamine derivatives
06/19/1985EP0144750A2 Antibiotics, method for their preparation, their use as medicines and intermediates for their preparation
06/19/1985EP0144709A2 Heat treatment of plasma fractions
06/12/1985EP0144170A1 Biosynthesis of unnatural cephalosporins
06/12/1985EP0143836A1 Expression and secretion vectors and method of constructing vectors
06/12/1985EP0143834A1 Heat regulated production of selected and fused proteins in yeast
06/12/1985EP0143821A1 Production of catechol 2,3-oxygenase by means of yeasts, plasmide for the implementation thereof and application
06/12/1985EP0143807A1 Method for immobilizing proteins or enzymes
06/11/1985CA1188643A1 Production of aryl acylamidases
06/06/1985WO1985002414A1 Method of catalyzing chemical reactions
06/05/1985EP0143560A2 Method for stabilizing the enzymic activity of phenylalanine ammonia lyase during L-phenylalanine production
06/05/1985EP0143381A2 Biphenylylalkanoic acid derivatives, methods of preparation and pharmaceutical compositions therefrom
06/05/1985EP0143195A1 Recombinant DNA having a phosphoenol pyruvate carboxylase gene inserted therein, bacteria carrying said recombinant DNA and a process for producing amino acids using said bacteria
05/1985
05/29/1985EP0143081A2 Synthesis of tissue plasminogen activator(TPA) by yeast
05/29/1985EP0142793A2 Process for the production of cholesterol esterase
05/28/1985US4520016 Bacteriolytic proteins
05/28/1985CA1187870A1 Tripeptide inhibitors of angiotensin-converting enzyme
05/28/1985CA1187825A1 Separation and purification process of the protease and antiprotease of blood coagulation and of the protease-antiprotease complex
05/28/1985CA1187787A1 Reverse transcriptase from human milk, method for its purification and its use in the detection of breast cancer
05/23/1985WO1985002197A1 Method, compound and composition for effecting degradation of crude petroleum and petroleum products in an environment
05/23/1985WO1985002196A1 Method, compound and composition for effecting degradation of crude petroleum and petroleum products in an environment
05/22/1985EP0142169A2 2,5-Diketo-D-gluconic acid reductase
05/21/1985US4518697 Acid stable protease from mutants of genus Aspergillus
05/21/1985US4518695 Process for eluting egg white lysozyme
05/21/1985US4518694 Stabilized with salt of lower molecular weight acid in alcohol
05/21/1985US4518692 Production of L-amino acids by transamination
05/21/1985US4518526 Purification and activity assurance of precipitated heterologous proteins
05/21/1985CA1187430A1 Mutant strain of escherichia coli and its use for the preparation of glutathione
05/21/1985CA1187411A1 Process for the preparation of plasminogen and plasminogen thus prepared
05/21/1985CA1187410A1 Pasteurized therapeutically active protein compositions
05/21/1985CA1187388A1 Stabilization of working reagent solutions containing nadh, nadph, and/or enzymes, and the use of such stabilized reagents in enzymes or substrate assays
05/15/1985EP0140966A1 Process in the purification of biologically active substances.
05/14/1985US4517299 Acetylesterases
05/14/1985US4517290 Method for enzyme immunoassay and peptide-enzyme conjugate and antibody therefor
05/14/1985US4517241 Chromatographic support material
05/14/1985CA1187012A1 Modification of micro-organisms
05/14/1985CA1187011A1 Method for making genetically modified micro- organisms
05/14/1985CA1186990A1 Stabilization process
05/14/1985CA1186937A1 Antistaling baking composition
05/09/1985WO1985001941A1 Method for the purification and isolation of blood clotting proteins using conformation specific antibodies
05/08/1985EP0140864A1 Externalization of products of bacteria
05/08/1985EP0140714A2 Method for the production of phenylalanine ammonia-lyase by fermentation
05/08/1985EP0140713A2 Method for production and recovery of L-Phenylalanine
05/08/1985EP0140707A2 Phenylalanine ammonia lyase-producing microbial cells
05/08/1985EP0140669A1 Microbial enzymatic contact lens cleaner and methods of use
05/08/1985EP0140610A2 A process for producing thermostable alpha-amylases by culturing micro-organisms at elevated temperatures
05/08/1985EP0140410A1 Novel enzyme product and its use in the saccharification of starch
05/08/1985EP0140004A2 Bilirubin-specific enzymes and their use in analytical elements and methods
05/08/1985EP0139985A1 Process and reagent for the determination of transaminases
05/08/1985EP0139705A1 Enzyme extraction and purification processes
05/07/1985US4515891 Process for the production of disaccharide-tripeptide and disaccharide-tetrapeptide
05/07/1985CA1186649A1 Process for producing crude elastase
05/07/1985CA1186627A1 Process for making novel blood clotting enzyme compositions
05/07/1985CA1186626A1 Process for the purification of the blood clotting factors ii, vii, ix and/or x and preparation prepared by this process
05/02/1985EP0139501A2 The manufacture and expression of genes for thaumatin