Patents for C12N 9 - Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes (141,535)
11/1991
11/05/1991US5063154 Genetic engineering
11/05/1991US5062465 Procedure for conveying molds, and a plant for that purpose
11/05/1991CA1291708C Solubilization of proteins for pharmaceutical compositions using polymer conjugation
11/03/1991WO1991017247A1 Protease deficient bacterial hosts
11/03/1991CA2081342A1 Protease deficient bacterial hosts
11/03/1991CA2041619A1 Mammalian inducible promoter cascade system
11/02/1991CA2040099A1 Tyrosine kinase negative trkb
10/1991
10/31/1991WO1991016901A1 Oligonucleotide modulation of arachidonic acid metabolism
10/31/1991WO1991016457A1 Cloning by complementation and related processes
10/31/1991WO1991016449A1 Saccharide compositions, methods and apparatus for their synthesis
10/31/1991WO1991016446A1 In vitro dna synthesis reactions using phi 29 dna polymerase and a dna fragment encoding said polymerase
10/31/1991WO1991016435A1 Mutated beta-lactam acylase genes
10/31/1991WO1991016424A1 Process for specific alteration of the properties of enzymes by chemical modification and chemically modified enzymes
10/31/1991WO1991016423A1 Oxidation stable detergent enzymes
10/31/1991WO1991016422A1 Alkaline bacillus lipases, coding dna sequences therefor and bacilli which produce these lipases
10/31/1991WO1991016421A1 Plant thioesterases
10/31/1991WO1991016420A1 Methods of preventing viral replication
10/31/1991WO1991016417A1 Methods and compositions for modulating ethylene levels in plant tissues
10/31/1991WO1991016340A1 Methods and compositions for the identification, characterization and inhibition of farnesyl protein transferase
10/31/1991WO1991016069A1 Selective cytotoxic reagents comprising toxic moieties derived from mammalian proteins
10/31/1991WO1991016060A1 Method of inactivation of viral and bacterial blood contaminants
10/31/1991WO1991016020A1 Transpedicular screw system and method of use
10/31/1991WO1991009118A3 Activatable fibrinolytic and anti-thrombotic proteins
10/31/1991DE4013142A1 Verfahren zur gezielten veraenderung der eigenschaften von enzymen durch chemische modifizierung und chemisch modifizierte enzyme Methods for the specific change in the properties of enzymes by chemical modification and chemically modified enzymes
10/31/1991CA2081769A1 Oligonucleotide modulation of arachidonic acid metabolism
10/31/1991CA2081319A1 Methods and compositions for modulating ethylene levels in plant tissues
10/31/1991CA2081122A1 Plant thioesterases
10/31/1991CA2081022A1 Methods of preventing viral replication
10/31/1991CA2062715A1 Saccharide compositions, methods and apparatus for their synthesis
10/30/1991EP0454478A1 Cephalosporin acetylhydrolase gene and protein encoded by said gene
10/30/1991EP0454463A2 Process for producing epoxyalcohols of high optical purity
10/30/1991EP0453656A1 Process for production of lignolytic enzymes by phanerochaete chrysosporium
10/30/1991EP0453556A1 Pneumocystis carinii dihydrofolate reductase gene and methods for its use
10/30/1991EP0333740B1 Pharmaceutically active conjugates having improved body tissue binding specificity
10/30/1991CN1055739A Hemihydrate
10/30/1991CA2041422A1 .alpha.-glycosyl naringin, and its preparation and uses
10/29/1991US5061789 Method of isolating blood-clotting factor ix
10/29/1991US5061730 Inhibitors of dehydropeptidase and renal dipeptidase; prevent unnecessary hydrolysis of beta-lactam ring of carbapenem antib iotics
10/29/1991US5061718 Benzothiazolylmethoxy compounds, pharmaceutical compositions comprising the same and their use as anti-inflammatory or anti-allergenic agents
10/29/1991US5061628 Isolation from culture of frankia; specific cleavage of dna in adenovirus
10/29/1991US5061627 Method for preparing enzymes from crustaceans
10/29/1991US5061625 Process for the preparation of a microorganism which forms α-galactosidase but not invertase, a microorganism thus obtained, and its use
10/28/1991WO1991016900A1 Fucosyl transferases involved in adhesion molecule expression
10/27/1991CA2039857A1 Process for producing epoxyalcohols of high optical purity
10/26/1991WO1991016440A1 Dna, dna constructs, cells and plants derived therefrom
10/26/1991CA2081454A1 Dna, dna constructs, cells and plants derived therefrom
10/25/1991WO1991016628A1 Purification, detection and methods of use of protease nexin-2
10/25/1991CA2079880A1 Purification, detection and methods of use of protease nexin-2
10/24/1991DE4012351A1 Macerating enzyme prepn. obtd. from Aspergillus niger - contains polygalacturonase, pectin-esterase and proto-pectinase, which are used in the work up of flax
10/23/1991EP0453242A1 Transfer and expression of gene sequences into central nervous system cells using herpes simplex virus mutants with deletions in genes for viral replication
10/23/1991EP0453195A1 (S)-alkyl 3-(thien-2-ylthio) butyrate and analogs and synthesis thereof
10/23/1991EP0453048A1 Mutated beta-lactam acylase genes
10/23/1991EP0453047A1 Penicillin G acylase, a gene encoding the same and a method for the production of this enzyme
10/23/1991EP0452587A1 Dihydroxy sulfonamide and sulfinamide renin inhibitors
10/23/1991CN1055560A Vectors and compounds for expression of glycosylation mutants of human protein c
10/22/1991WO1991016414A1 Process for the production of lignolytic enzymes by means of phanerochaete chrysosporium
10/22/1991US5059535 Process for the separation and purification of sialyl transferases
10/22/1991US5059529 Stabilized expression vectors containing λPL promoter and the gene for the cI434 repressor, plasmids containing the vectors, hosts containing the plasmids and related methods
10/22/1991US5059341 Cleaning composition comprising microbial lipase SD2, sodium dodecylbenzene sulfonate and gelatin
10/22/1991CA1291125C Pyrimidine derivatives
10/21/1991WO1991016426A1 ENDO-1,4-β-GLUCANASE GENES AND THEIR USE IN PLANTS
10/21/1991CA2401776A1 Plants and tubers expressing patatin and adp-clucose-pyrophosphorylase sequences
10/21/1991CA2040773A1 Naphthalene derivatives
10/19/1991CA2040605A1 (s)-alkyl 3-(thien-2-ylthio)butyrate and analogs and synthesis thereof
10/17/1991WO1991015589A1 Improved process of purifying recombinant proteins and compounds useful in such process
10/17/1991WO1991015588A1 Recombinant yeasts containing the dna sequences coding for xylose reductase- and xylitol dehydrogenase enzymes
10/17/1991WO1991015587A1 Self-polymerising expression system based on modified potyvirus coat proteins
10/17/1991WO1991015581A1 Walk-through mutagenesis
10/17/1991WO1991015580A1 Gene therapy for cell proliferative diseases
10/17/1991WO1991015577A1 INTERLEUKIN 1 beta PROTEASE
10/17/1991WO1991015576A1 Treatment of thrombotic events
10/17/1991WO1991015572A1 Live vaccines
10/17/1991WO1991015514A1 Oxidation resistant thrombomodulin analogs
10/17/1991WO1991015235A1 t-PA ENHANCER PROFILE
10/17/1991WO1991015234A1 Recombinant bile salt activated lipases
10/17/1991WO1991015216A1 Method and medicament for prevention or medication of human leucocyte elastase-mediated pulmonary diseases
10/17/1991WO1991011513A3 Catechol-o-methyltransferase, polypeptide sequences and dna molecule coding therefor
10/17/1991DE4111321A1 New alkaline lipase from Bacillus species - used in low temp., washing, cleaning etc. compsns., also encoding deoxyribonucleic acid, vectors and transformed microorganisms
10/17/1991CA2079903A1 Gene therapy for cell proliferative diseases
10/17/1991CA2039921A1 Transfer and expression of gene sequences into central nervous system cells using herpes simplex virus mutants with deletions in genes for viral replication
10/16/1991EP0452264A1 Hydroxylamine compounds
10/16/1991EP0452112A1 Cholesterol oxidase
10/16/1991EP0451972A1 Utilization of enzymes
10/16/1991EP0451957A2 Cyclohexapeptide compound
10/16/1991EP0451896A1 New yeast strains with enhanced trehalose content, process to obtain such yeasts and the use of these yeasts
10/16/1991EP0451823A2 DNA constructs for expression of proteins in the lacteal gland of transgenic mammals
10/16/1991EP0451452A1 A recombinant plasmid for lipase expression and a process for producing a lipase
10/16/1991EP0451436A2 Method of curing and preventing obesity by alpha-amylase inhibitor
10/16/1991EP0451357A1 Pathogenesis factors of dermatophytes
10/16/1991EP0451270A1 Process for preparing asialo gm1
10/16/1991EP0451267A1 Process for preparing ganglioside gm1
10/16/1991EP0451244A1 Subtilisin mutants
10/16/1991EP0277151B1 Novel medicinal use of nucleosides
10/16/1991EP0229810B1 Protection of proteins and the like
10/15/1991US5057496 Dipeptide compounds containing histidine or n-methyl histidine processes for their preparation and compositions containing them
10/15/1991US5057419 Genetically engineered plasmid and organisms for the production of specialized oils
10/15/1991US5057418 Treating inulin solution with heat resistant enzyme from arthrobacter; efficiency
10/15/1991US5057416 For polypeptide products
10/12/1991CA2040178A1 Dna constructs for the expression of proteins in the mammary gland of transgenic mammals
10/12/1991CA2040103A1 Hydroxylamine compounds