Patents for C12N 9 - Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes (141,535)
12/2000
12/26/2000US6165991 A polynucleotide, or the full complement of the entire length of the polynucleotide, which encodes the same mature polypeptide, expressed by histidine kinase encoded by a specific polynucleotide contained in streptococcus pneumoniae
12/26/2000US6165989 An isolated polynucleotide comprising a first polynucleotide or the full complement of the entire length of the first polynucleotide, wherein the first polynucleotide encodes a polypeptide comprising specific amino acid sequence
12/26/2000US6165981 Stabilizing solutions for proteins and peptides
12/26/2000US6165977 Isozyme-specific activators of protein kinase C methods and compositions
12/26/2000US6165974 Administering an effective dose of a pharmaceutical preparation comprising at least two coagulation factors which are components of a prothrombinase or of a pro-prothrombinase to the patient for the treatment of acute bleeding
12/26/2000US6165960 Use of alkaline proteases in industrial textile laundering processes
12/26/2000US6165794 Suppression of proteolytic activity by dysfunctional protease formation
12/26/2000US6165793 Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
12/26/2000US6165774 Culturing virus in cells, separating out virus, solubilizing hemagglutinin-neuramidase and fusion envelope glycoproteins from virus, and coisolating and copurifying using ion exchange chromatography and hydroxyapatite matrix
12/26/2000US6165771 Compounds
12/26/2000US6165770 Alkaline stable amylase from Thermoalcalibacter
12/26/2000US6165769 Pectin degrading enzymes from Bacillus licheniformis
12/26/2000US6165766 Amino acid sequence of serine/threonine protein kinase; anticarcinogenic/antiarthritic/antiinflammatory agents; treatment of osteoporosis, adult respiratory disease syndrome, inflammatory bowel disease, eating disorders; diagnosis
12/26/2000US6165765 Heat resistant enzyme from bacillus; for more accurate sequence determination using chain terminating nucleotides
12/26/2000US6165764 Polynucleotides encoding tRNA methyl transferases from Streptococcus pneumoniae
12/26/2000US6165763 Nucleotide and amino acid sequences of enzyme from streptococcus; for drug screening of bacteriostats and bactericides
12/26/2000US6165762 Amino acid sequence of enzyme; drug screening of bactericides and bacteriostats; vaccines; diagnosis of infections
12/26/2000US6165761 Carbohydrate oxidase and use thereof in baking
12/26/2000US6165760 Amino acid sequence of polypeptide of the glutamyl transfer rna synthetase family; drug screening of bacteriostats and bactericides; vaccines; diagnosis of infections
12/26/2000US6165759 Amino acid sequence; diagnosis, prophylaxis and therapy of infections; vaccines; bacteriostats; bactericides; screening of enzyme inhibitors and activators
12/26/2000US6165758 Purifying cephalosporin c acylase from mixture with deacetylase contaminant by selectively aggregating and precipitating deacetylase using benzylated or methylated cationic surfactant in amount of 0.1 to 0.6 percent
12/26/2000US6165749 Plasmid vector comprising promoter sequence to control expression of desired gene, said promoter sequence being recognized by rna polymerase derived from sp6 phage, and a replication origin for increasing copy number by induction
12/26/2000US6165738 Hybrid of two human isoforms; for recombinant production; for diagnosis, presymptomatic detection, and prevention of insulin dependent diabetes mellitus
12/26/2000US6165735 Parasitic helminth asparaginase proteins, nucleic acid molecules, and uses thereof
12/26/2000US6165733 γ II adaptin
12/26/2000US6165712 Contacting a cell with an exogenous molecule effective to modulate gene expression and affect level of protein thus pathological effect; molecule binds to regulatory sequence, rna, or transcription regulating protein; viricides
12/26/2000US6165478 DNA encoding Chlamydia pneumoniae antigenic polypeptide
12/26/2000US6165472 Folyl-polyglutamate synthetase (fpgs) of s. pnuemoniae is necessary for a fully functional folate synthesis pathway. having a present benefit of being useful to screen compounds for antibiotic activity.
12/26/2000US6165462 Sugar kinase
12/26/2000US6165461 Tao protein kinases and methods of use therefor
12/26/2000US6165460 Generation of immune responses to prostate-specific antigen (PSA)
12/26/2000CA2182476C Macrocyclic difluorostatone derivatives useful as antiviral agents
12/21/2000WO2000077281A1 Encapsulation of crystals via multilayer coatings
12/21/2000WO2000077262A1 Synthetic ligation reassembly in directed evolution
12/21/2000WO2000077229A2 R1 protein from wheat and the use thereof for the production of modified strach
12/21/2000WO2000077226A1 22025, a novel human cyclic nucleotide phosphodiesterase
12/21/2000WO2000077225A1 A novel insulin signaling molecule
12/21/2000WO2000077224A1 Method of increasing the content of fatty acids in plant seeds
12/21/2000WO2000077223A1 Promoter enabling transgene expression in the whole plant except in the seed
12/21/2000WO2000077222A1 Genes encoding enzymes in the biosynthesis of pimaricin and the application thereof
12/21/2000WO2000077221A1 Hyaluronidase from the hirudinaria manillensis, isolation, purification and recombinant method of production
12/21/2000WO2000077207A2 Nucleic acid encoding proteins involved in protein degradation, products and methods related thereto
12/21/2000WO2000077200A1 Receptor interacting protein rip3
12/21/2000WO2000077193A1 Enzyme selection
12/21/2000WO2000077190A2 Induction of vascular endothelial growth factor (vegf) by the serine/threonine protein kinase akt
12/21/2000WO2000077187A2 Promoter system and production and use of the same
12/21/2000WO2000077185A2 Herbicide target genes and methods
12/21/2000WO2000077184A1 Caspase-8 crystals, models and methods
12/21/2000WO2000077183A1 Enzymatic preparation of phospholipids in aqueous media
12/21/2000WO2000077182A1 Nucleic acid fragment and vector containing halogenase and method for the halogenation of chemical compounds
12/21/2000WO2000077180A1 A reductase
12/21/2000WO2000077179A2 Human poly(adp-ribose) polymerase 2 materials and methods
12/21/2000WO2000077178A1 IMMUNOLOGICAL CONTROL OF β-AMYLOID LEVELS IN VIVO
12/21/2000WO2000077172A1 Process for producing l-lysine
12/21/2000WO2000077168A2 ANTAGONISTS OF BMP AND TGFβ SIGNALLING PATHWAYS
12/21/2000WO2000077024A1 Camello gene family and uses thereof
12/21/2000WO2000054052A3 Diagnostic test
12/21/2000WO2000053782A3 Herbicide target genes and methods
12/21/2000WO2000053737A3 Mitomycin biosynthetic gene cluster
12/21/2000WO2000053732A3 Class ii dna methyltransferases of zea mays
12/21/2000WO2000049158A3 Psa and klk-2 splicing variants
12/21/2000WO2000048621A3 Methods and compositions for regulating protein-protein interactions
12/21/2000WO2000044391A3 Plasminogen kringle 4 region fragments and methods of use
12/21/2000WO1998021230A8 Cyclic peptides that bind to urokinase-type plasminogen activator receptor
12/21/2000DE19928313A1 Verfahren zur Veränderung von Peptidsynthefasen in der Weise, daß sie ihre Substrataminosäuren N-methylieren können Method for changing Peptidsynthefasen in such a way that they can make their substrate amino acids N-methylated
12/21/2000DE19928021A1 New nucleic acid encoding testis-specific calpain-11, useful for identifying specific inhibitors for treatment of fertility disorders
12/21/2000DE19927575A1 Increasing resistance of crop plants to fungal or bacterial pathogens, by engineering a reduction in activity of flavanone-3-hydroxylase
12/21/2000DE19927574A1 Increasing content of flavonoids and phenols in plants, useful for e.g. preventing cardiovascular disease, by reducing activity of flavanone-3-hydroxylase
12/21/2000DE19927568A1 Increasing resistance of crop plants to chemical stress, especially herbicides, by engineering a reduction in activity of flavanone-3-hydroxylase
12/21/2000CA2377592A1 Method of modifying peptide synthetases such that they can n-methylate their substrate amino acids
12/21/2000CA2376878A1 Promoter enabling transgene expression in the whole plant except in the seed
12/21/2000CA2376717A1 Human poly(adp-ribose) polymerase 2 materials and methods
12/21/2000CA2376693A1 Immunological control of .beta.-amyloid levels in vivo
12/21/2000CA2376675A1 Antagonists of bmp and tgf.beta. signalling pathways
12/21/2000CA2376630A1 Induction of vascular endothelial growth factor (vegf) by the serine/threonine protein kinase akt
12/21/2000CA2376621A1 Enzyme selection
12/21/2000CA2376604A1 Enzymatic preparation of phospholipids in aqueous media
12/21/2000CA2376467A1 Hyaluronidase from the hirudinaria manillensis, isolation, purification and recombinant method of production
12/21/2000CA2376446A1 Nucleic acid fragment and vector containing halogenase and method for the halogenation of chemical compounds
12/21/2000CA2376437A1 Promoter system and production and use of the same
12/21/2000CA2376142A1 Camello gene family and uses thereof
12/21/2000CA2375317A1 Method of increasing the content of fatty acids in plant seeds
12/21/2000CA2370405A1 Nucleic acid molecules from wheat, transgenic plant cells and plants and the use thereof for the production of modified starch
12/20/2000EP1061130A1 Rna polymerase transcription promoters and method for determining base sequence
12/20/2000EP1061085A2 Synthetic catalytic oligonucleotides
12/20/2000EP1060263A1 Method and compositions for detecting luciferase in biological samples
12/20/2000EP1060260A2 Elongation factor-2 kinase (ef-2 kinase) and methods of use therefor
12/20/2000EP1060259A2 Novel means and methods for the preparation and activation of nucleoside and nucleotide based drugs
12/20/2000EP1060257A1 Method for the induction of pathogen resistance in plants
12/20/2000EP1060256A1 Novel sphingosine-1 phosphate lyase
12/20/2000EP1060255A2 Highly crystalline urokinase
12/20/2000EP1060254A2 Human proteinase molecules
12/20/2000EP1060253A2 Modified forms of pullulanase
12/20/2000EP1060252A2 Human platelet heparanase polypeptides, polynucleotide molecules that encode them, and methods for the identification of compounds that alter heparanase activity
12/20/2000EP1060251A2 Phosphodiesterase 10
12/20/2000EP1060250A1 Modification of fatty acid metabolism in plants
12/20/2000EP0671934B1 Method of treating cell damage or depletion
12/20/2000CN1277637A Method for preparing a substituted benzamide
12/20/2000CN1277635A Nucleic acids having promoter activity and transgenic plants containing the same
12/20/2000CN1277634A New tissue-specific calpaines, their production and their use