Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
06/1990
06/19/1990CA2005809A1 Cysteine biosynthesis
06/19/1990CA2005744A1 Method for transforming human b lymphocytes
06/19/1990CA2005658A1 Insecticidal toxins, genes encoding these toxins, antibodies binding to them and transgenic plant cells and plants expressing these toxins
06/19/1990CA1270453A1 Shuttle vector
06/16/1990CA2005720A1 .alpha.-plasmin inhibitor analogue and a highly productive plasmid for expression of .alpha.-plasmin inhibitor
06/16/1990CA2005667A1 Isolating thermostable enzymes from engineered mesophiles
06/16/1990CA2005639A1 Lymphokine/cytokine genes
06/16/1990CA2005459A1 Cloning and expression of transforming growth factor beta-2
06/16/1990CA2003886A1 Cloning and expression of simian transforming growth factor-beta 1
06/15/1990CA2005597A1 Plants having reduced lignin or lignin of altered quality
06/15/1990CA2005120A1 Tgf-beta 1/beta 2: a novel chimeric transforming growth factor-beta
06/14/1990WO1990006510A1 Monoclonal antibodies to feline-t-lymphotropic lentivirus
06/14/1990WO1990006509A1 Isolation of fetal cells from maternal blood to enable prenatal diagnosis
06/14/1990WO1990006374A1 Amplified dna assay
06/14/1990WO1990006371A1 ANTI-INTERLEUKINE 1α AND 1β MONOCLONAL ANTIBODIES, METHOD FOR PRODUCING THE SAME AND APPLICATIONS OF SAID ANTIBODIES TO THE DETECTION OF INTERLEUKINES 1α AND 1β AND TO THERAPY
06/14/1990WO1990006370A1 Synthetic interleukin-6
06/14/1990WO1990006369A1 Use of hiv protease cleavage site to express mature proteins
06/14/1990WO1990006367A1 Transgenic mice for the analysis of hair growth
06/14/1990WO1990006366A1 Heat-labile toxin b subunit fusion proteins
06/14/1990WO1990006365A1 Recombinant proteins with adipsin and complement d activities
06/14/1990WO1990006364A1 Drosophila receptors homologous to mammalian steroid receptors
06/14/1990WO1990006363A1 Expression induction method employing mutant dhfr gene
06/14/1990WO1990006362A1 Ancrod proteins, their production and use
06/14/1990WO1990006359A1 Transgenic non-human animals depleted in a mature lymphocytic cell-type
06/14/1990WO1990006358A1 Expression of hiv proteins in drosophila cells
06/14/1990WO1990006323A2 Chimeric proteins incorporating a metal binding protein
06/14/1990WO1990006321A1 Neutrophil-activating peptide-2
06/14/1990WO1990006318A1 Novel receptors: their identification, characterization, preparation and use
06/14/1990WO1990006132A1 Method for the preparation of a library of antigenic peptide determinants, new peptides formed of or including the antigenic determinants obtained and application of the peptides particularly to diagnosis
06/14/1990WO1990006047A2 Human high-affinity neurotransmitter uptake system
06/14/1990WO1990006045A2 Nucleic acid probes
06/14/1990WO1990006044A2 PROCESS FOR PRODUCING cDNA
06/14/1990WO1990006043A2 In vitro mutagenesis
06/13/1990WO1990015864A1 Processes for the recovery of microbially produced chymosin
06/13/1990EP0373070A1 Preparation of a library of peptidic antigenic determinants, new peptides built from or containing these determinants and use thereof, namely for diagnosis
06/13/1990EP0373012A1 DNA encoding for factor IX or an analogous protein
06/13/1990EP0372928A2 Heat-labile toxin B subunit fusion proteins
06/13/1990EP0372904A2 Protease, reverse transcriptase, and endonuclease of retroviruses and method for producing these enzymes
06/13/1990EP0372707A2 Modified proteins, modified interferons, alphas and beta, phosphorylated proteins and analogues, DNA sequences, applications and uses thereof
06/13/1990EP0372524A2 Method of enrichment and cloning for DNA containing an insertion or corresponding to a deletion
06/13/1990EP0372352A2 Aequorin fused with a protein having a specific-binding activity, its preparation, its purification and detection method by its use
06/13/1990EP0372230A2 Method for the conjugational transfer of mobilisable vectors from E.coli to gram-positive bacteria, and vectors suitable therefor
06/13/1990EP0372063A1 Human myeloperoxydasis and its therapeutic application.
06/13/1990EP0372056A1 Protein micelles
06/13/1990EP0372005A1 Expression systems for preparation of polypeptides in prokaryotic cells
06/13/1990EP0227772B1 Nucleic acid sequencing by exonuclease inhibition
06/13/1990EP0203143B1 An assay for nucleic acid sequences, particularly genetic lesions
06/13/1990CN1042940A Diagnostic reagent for identifying of serum antibody of poor and sick horse and horse inoculated with less toxic vaccine
06/13/1990CN1008377B Bacterial enzymes
06/13/1990CA2005199A1 Genetically engineered endothelial cells and use thereof
06/13/1990CA2002047A1 Serineprotease inhibitor proteins, pharmaceutical compositions containing them, dna sequences coding for these proteins and processes for the preparation of these proteins, pharmaceutical compositions and dna sequences
06/12/1990US4933433 Recombinant interleukin-2 composition and process for making it
06/12/1990US4933288 Dna sequence encoding proteins processable by diphtheria toxin leaders
06/12/1990US4933286 Purification of apase-11 and retrieval of the nematode resistance gene
06/12/1990US4933280 Treatment of respiratory deficiency syndrome
06/12/1990US4933275 Method for the detection of a polypeptide subunit in the presence of a quaternary protein containing the subunit
06/12/1990CA2005245A1 Thrombolytic proteins, process for producing the same, and drugs containing the same as active ingredient
06/12/1990CA1270217A1 Recombinant plasmid provided with hepatitis b virus gene, yeast transformed with said recombinant plasmid, and production of hepatitis b virus surface antigen
06/12/1990CA1270216A1 Processes for the preparation of obligate methylotrophic bacteria which express foreign dna, and plasmids and host organisms suitable for these
06/09/1990CA2004990A1 Amplified dna assay
06/08/1990CA2004935A1 Monoclonal antibodies to anti-interleukines-1 .alpha. and 1 .beta., process for their production and use of the antibodies for the detection of interleukines-1 .alpha. and 1-.beta. in therapeutics
06/08/1990CA2004685A1 Neutrophil-activating peptide-2
06/07/1990DE3840890A1 Method for the chromatographic fractionation of nucleic acids
06/07/1990CA2004738A1 Heat-labile toxin b subunit fusion proteins
06/06/1990EP0371820A2 Novel receptors: their identification, characterization, preparation and use
06/06/1990EP0371712A2 Bacterial extracellular lignin peroxidase
06/06/1990EP0371437A2 Method and reagent combination for determining nucleotide sequences
06/06/1990EP0371199A1 Novel protein H being capable of binding to IgG, gene coding for said protein H and a process for producing said protein H
06/06/1990EP0371056A1 Methods and compositions for mimicking antigenic determinants
06/06/1990EP0371041A1 A process for preparing a protein or polypeptide, a dna sequence coding for the polypeptide, a microorganism containing the dna sequence as well as the polypeptide and its use as a pharmaceutical preparation
06/06/1990CN1042734A Monoclonal antibodies identifying alpha 2-3 linkage
06/06/1990CN1042638A Method for transforming plants via shoot apex
06/06/1990CA2004592A1 Isolation of fetal cells from maternal blood to enable prenatal diagnosis
06/05/1990US4931543 Process for recovering microbially produced interleukin-2
06/05/1990US4931396 pTR2030, a conjugal plasmid and derivatives thereof that confer phage reisistance to group N streptococci
06/05/1990US4931395 Monoclonal antibody specific to neutrophils
06/05/1990US4931390 Expression of the cloned lysostaphin gene
06/05/1990US4931373 Stable DNA constructs for expression of α-1 antitrypsin
06/05/1990CA2004477A1 Transgenic non-human animals depleted in a mature lymphocytic cell-type
06/05/1990CA1269930A1 Anticytomegalovirus monoclonal antibodies and processes for the in vitro diagnosis of infections by human cytomegaloviruses and of a protein-kinase inducible by cytomegaloviruses and which can be recognised by the abovesaid monoclonal antibodies
06/01/1990CA2004261A1 Synthetic interleukin-6
05/1990
05/31/1990WO1990005917A1 Pyruvate-kinase-isoenzyme-type-m2 (tumour m2-pk) specific antibodies, process for producing them and use
05/31/1990WO1990005789A1 In situ suppression hybridization and uses therefor
05/31/1990WO1990005788A1 Expression of dna sequences derived from nocardioform microorganisms
05/31/1990WO1990005787A1 Position-specific insertion vectors and method of using same
05/31/1990WO1990005786A1 Cloned genes which encode elam-1 and fusion proteins thereof, the protein products expressed therefrom, pharmaceutical compositions and the use thereof
05/31/1990WO1990005785A1 Method for site-specifically incorporating unnatural amino acids into proteins
05/31/1990WO1990005784A1 Process for preparing 5'-inosinic acid
05/31/1990WO1990005783A1 Insect signal peptide mediated secretion of recombinant proteins
05/31/1990WO1990005781A1 Neural cell transplantation
05/31/1990WO1990005780A1 Dopamine receptors and genes
05/31/1990WO1990005777A1 Purification of factor xiii
05/31/1990WO1990005775A1 DNA ENCODING [Lys?46, Asp97, Asp113¿] AND [Lys?46, Asp113, Asp137¿] THAUMATIN I POLYPEPTIDES
05/31/1990WO1990005748A1 Scavenger receptor protein and antibody thereto
05/31/1990WO1990005746A1 Catalytic and reactive polypeptides and methods for their preparation and use
05/31/1990WO1990005745A1 A cAMP-RESPONSIVE TRANSCRIPTIONAL ENHANCER BINDING PROTEIN
05/31/1990WO1990005742A1 Fish crf
05/31/1990WO1990005741A1 Laminin a chain deduced amino acid sequence, expression vectors and active synthetic peptides
05/31/1990WO1990005737A1 Cloning and expression of a protein which modulates cellular response to type i interferon
05/31/1990WO1990005539A1 Antibodies specific for elam-1 and the use thereof