Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
06/1993
06/29/1993US5223421 Identification of methionine Nα-acetyltransferase
06/29/1993US5223419 Alteration of gene expression in plants
06/29/1993US5223418 Using casamino acid
06/29/1993US5223409 Directed evolution of novel binding proteins
06/29/1993US5223408 Method for making variant secreted proteins with altered properties
06/29/1993US5223407 Culturing genetically transformed E. coli strains
06/29/1993US5223394 Recombinant dna molecule comprising lymphocyte function-associated antigen 3 phosphatidylinositol linkage signal sequence
06/29/1993US5223392 Monoclonal antibodies against glycated albumin, hybrid cell lines producing these antibodies, and use therefore
06/29/1993US5223256 Thrombolytically active non-glycosylated protein
06/29/1993US5223254 Polypeptide
06/29/1993CA2121134A1 Novel thrombin-inhibitory protein from ticks
06/29/1993CA1319631C Method for the production of proteins by means of inducible expression systems in genetically modified eukaryotic host-cells multiplicated in-vivo
06/29/1993CA1319630C Method of regulating expression of a foreign gene by controlling the sugar concentration in a medium and a process of producing a foreign gene product thereby
06/29/1993CA1319629C Fusion proteins
06/29/1993CA1319628C Fusion proteins
06/28/1993CA2086162A1 Oligonucleotides, oligopeptides and determination system of hcv antibody subtype
06/25/1993CA2126748A1 Manipulating nucleic acid sequences
06/24/1993WO1993012257A1 Enzymatic inverse polymerase chain reaction library mutagenesis
06/24/1993WO1993012251A1 Senescent cell derived inhibitors of dna synthesis
06/24/1993WO1993012247A1 In vitro antibody production
06/24/1993WO1993012246A1 Expression-secretion vectors for the production of biologically active fv fragments
06/24/1993WO1993012245A1 Method for exponential amplification of nucleic acid by a single unpaired primer
06/24/1993WO1993012244A1 Construction of geometrical objects from polynucleotides
06/24/1993WO1993012240A1 Gene therapy for cystic fibrosis transmembrane conductance regulator activity (cftr)
06/24/1993WO1993012239A1 Alteration of plant and plant cell growth characteristics
06/24/1993WO1993012238A1 t-PA SUBSTITUTION VARIANTS WITH IMPROVED FIBRIN-SPECIFICITY
06/24/1993WO1993012237A1 Process for producing/secreting a protein by a transformed mould using expression/secretion regulating regions derived from an aspergillus endoxylanase ii gene
06/24/1993WO1993012236A1 Constitutive expression of p450soy and ferredoxin-soy in streptomyces, and biotransformation of chemicals by recombinant organisms
06/24/1993WO1993012235A1 Materials and methods for biosynthesis of serine and serine-related products
06/24/1993WO1993012234A1 Antiviral reagents based on rna-binding proteins
06/24/1993WO1993012233A1 Mammalian cell-based dna libraries
06/24/1993WO1993012232A1 Reactive neutralizing human anti-gp120 recombinant antibody, dna coding the same and use thereof
06/24/1993WO1993012231A1 Composite antibodies of human subgroup iv light chain capable of binding to tag-72
06/24/1993WO1993012230A1 Triple-helix formation at (punpyn).(punpyn) tracts
06/24/1993WO1993012229A1 Method for preparing double stranded rna, and use thereof
06/24/1993WO1993012228A1 Method for generating structural and functional diversity in a peptide sequence
06/24/1993WO1993012227A1 Transgenic non-human animals capable of producing heterologous antibodies
06/24/1993WO1993012225A1 Novel tissue plasminogen activator variants
06/24/1993WO1993012143A1 Dimer of molecular variant of apolipoprotein and processes for the production thereof
06/24/1993WO1993012134A1 Diagnosis of hereditary retinal degenerative diseases
06/24/1993WO1993012133A1 Transcriptional cofactor regulation of expression
06/24/1993WO1993012129A1 Peptide nucleic acids and their effect on genetic material
06/24/1993WO1993012127A1 PLATELET GPIIIa P1?A1 AND P1A2¿ EPITOPES, THEIR PREPARATION AND USE
06/24/1993WO1993011794A1 Methods and materials for preparation of modified antibody variable domains and therapeutic uses thereof
06/24/1993WO1993011792A1 Recombinant bovine herpesvirus type 1 polypeptides and vaccines
06/24/1993WO1993011257A3 Process for screening substances capable of modulating a receptor-dependent cellular signal transmission path
06/24/1993DE4142552A1 Monoklonale antikoerper gegen die typ i phospholipase a(pfeil abwaerts)2(pfeil abwaerts) als entzuendungshemmendes therapeutikum Monoclonal antibodies against type I phospholipase A (down arrow) 2 (down arrow) as therapeutic entzuendungshemmendes
06/24/1993DE4142452A1 Mittel zur stimulierung der teilungsaktivitaet tierischer zellen Means for stimulation of teilungsaktivitaet animal cells
06/24/1993CA2126101A1 Gene therapy for cystic fibrosis transmembrane conductance regulator activity (cftr)
06/24/1993CA2125966A1 Peptide nucleic acids and their effect on genetic material
06/24/1993CA2125947A1 Constitutive expression of p450soy and ferredoxin-soy in streptomyces, and biotransformation of chemicals by recombinant organisms
06/24/1993CA2125396A1 Reactive neutralizing human anti-gp 120 recombinant antibody, dna coding the same and use thereof
06/24/1993CA2125192A1 A process for generating a structural and functional diversity in a peptide sequence
06/24/1993CA2124786A1 In vitro antibody production
06/24/1993CA2085828A1 Serpulina hyodysenteriae vaccine
06/23/1993EP0548056A1 A process for cloning methylated DNA in a bacterial host incapable of host restriction
06/23/1993EP0548012A1 Endoplastic reticulum-located recombinant dibasic endoprotease and uses thereof
06/23/1993EP0547920A2 Recombinant thermostable DNA polymerase from archaebacteria
06/23/1993EP0547876A1 Gene encoding enzyme having flavin reducing activity and nitroreductase activity
06/23/1993EP0547873A2 A novel translational activating sequence
06/23/1993EP0547789A1 Process for lysing mycobacteria
06/23/1993EP0547631A2 Antibody expression vector and antibodies produced thereby
06/23/1993EP0547446A2 Vaccines based on modified bovine herpesvirus type I
06/23/1993EP0547403A1 Regulated expression of tetracycline resistance determinant (TETK) in escheria coli
06/23/1993EP0547359A1 Purified thermostable dna polymerase obtainable from pyrococcus species
06/23/1993EP0547201A1 Phagemide for screening antibodies
06/23/1993EP0547200A1 Recombinant antibodies at the surface of e. coli
06/23/1993EP0547180A1 Recombinant agents affecting thrombosis
06/23/1993EP0547171A1 Production of human lysozyme in methylotrophic yeast cells and efficient secretion therefrom
06/23/1993EP0547163A1 Protein polyligands joined to a stable protein core
06/23/1993EP0547149A1 Inhibition of herpesviridae infection by antisense oligonucleotides
06/23/1993EP0547076A1 Cd58-specific monoclonal antibodies and their use
06/23/1993EP0547074A1 Human mitochondrial nad(p)?+ -dependent malate enzyme
06/23/1993EP0547065A1 Melanin production by transformed microorganisms
06/23/1993EP0547059A1 Pancreas-elastasis-1-specific antibody, a process for obtaining it and a test kit containing such antibodies.
06/23/1993EP0263172B1 Protein analogues of tissue plasminogen activator
06/23/1993EP0249635B1 Word recognition in a speech recognition system using data reduced word templates
06/23/1993EP0236330B1 Dna sequence encoding a hirudin-like protein and process for preparing such protein
06/23/1993CN1073484A Methods and reagents for HLA class I DNA typing
06/23/1993CN1073476A Dye transfer inhibiting compositions
06/22/1993US5221789 Interferon-gamma receptor fragment and its production
06/22/1993US5221740 Oxepane isomers of rapamycin useful as immunosuppressive agents
06/22/1993US5221738 cDNA and genomic DNA encoding the amino acid sequence of human α2 -plasmin inhibition
06/22/1993US5221737 Gene and gene structure coding for an aminotransferase, and microorganisms which express this gene
06/22/1993US5221736 Sequential peptide and oligonucleotide syntheses using immunoaffinity techniques
06/22/1993US5221624 DNA encoding (Lys46, Asp97, Asp113) and (Lys46, Asp.sup.137) thaumatin I polypeptides
06/22/1993US5221623 Use of bacterial luciferase structural genes for cloning and monitoring gene expression in microorganisms and for tagging and identification of genetically engineered organisms
06/22/1993US5221620 Cloning and expression of transforming growth factor β2
06/22/1993US5221619 Method and means for microbial polypeptide expression
06/22/1993US5221618 Genetic detoxification of pertussis toxin
06/22/1993US5221608 Adding a polymerase and an isopsoralen compound to a mixture of nucleic acid and amplification reagents, and exposing to ultraviolet radiation to form isopsoralen monoadduct which inhibits polymerase
06/22/1993CA1319337C Newcastle disease virus gene clones
06/22/1993CA1319336C Means and method for enhancing nucleic acid hybridization
06/21/1993CA2085803A1 Purified para-nitrobenzyl esterase from bacillus
06/20/1993CA2085806A1 Recombinant dna compounds and expression vectors encoding para-nitrobenzyl esterase activity from bacillus
06/20/1993CA2058116A1 Production and secretion of proteins and polypeptides by yeast
06/19/1993CA2085447A1 A novel translational activating sequence
06/19/1993CA2059611A1 L-phenylalanyl-trna synthetase mutants, a process for the preparation thereof and the use thereof for the in vivo incorporation of non-proteinogenous amino acids into peptides or proteins
06/18/1993EP0597845A4 GROWTH FACTOR WHICH INHIBITS THE GROWTH OF CELLS OVEREXPRESSING THE HUMAN ONCOGENE erbB-2.
06/18/1993EP0559834A4 Immunoassay and monoclonal antibodies useful for detecting truncated nerve growth factor receptor.