Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
04/1999
04/07/1999EP0906428A1 Use of interleukin-10 to produce a population of suppressor cells
04/07/1999EP0906427A1 Characterization of transfer factors and methods of use
04/07/1999EP0906426A1 Antibodies to the ed-b domain of fibronectin, their construction and uses
04/07/1999EP0906425A2 Vasoactive amine binding molecules
04/07/1999EP0906424A2 Mammalian mixed lymphocyte receptors, chemokine receptors mmlr-ccr]
04/07/1999EP0906423A1 Metastasis-associated antigen and antibodies thereto
04/07/1999EP0906422A1 Human cell death-associated protein
04/07/1999EP0906421A1 Enhanced efficacy of liposomal antisense delivery
04/07/1999EP0906420A1 Programmed sequential mutagenesis
04/07/1999EP0906419A2 Peptide ligands of the urokinase receptor
04/07/1999EP0906418A1 Methods and compositions for cellular and metabolic engineering
04/07/1999EP0906413A2 Dna encoding alpha-(1,4)-glucan acetyl-transferase
04/07/1999EP0906337A2 AN ANTIGENIC EPITOPE OF THE u A /u DETERMINANT OF HEPATITIS B SURFACE ANTIGEN AND USES THEREOF
04/07/1999EP0906330A1 STREPTOCOCCUS PNEUMONIAE ISOLEUCYL tRNA SYNTHETASE
04/07/1999EP0906329A2 2'-substituted nucleosides and oligonucleotide derivatives
04/07/1999EP0906328A1 Methods and compounds for curing diseases caused by mutations
04/07/1999EP0906123A1 OLIGONUCLEOTIDES TARGETED TO ANGIOTENSINOGEN mRNA
04/07/1999EP0906119A1 Method of treatment
04/07/1999EP0906110A1 Dna vaccine formulations
04/07/1999EP0906019A1 LIVE ATTENUATED VACCINES BASED ON cp45 HPIV-3 STRAIN AND METHOD TO ENSURE ATTENUATION IN SUCH VACCINES
04/07/1999EP0792458A4 Methods for aiding in the diagnosis of alzheimer's disease by measuring amyloid-beta peptide (x- 41) and tau
04/07/1999EP0763112B1 Process for preparing doxorubicin
04/07/1999EP0754227A4 Chimeric complement inhibitor proteins
04/07/1999EP0752884A4 Method of treating auto-immune diseases using type one interferons
04/07/1999EP0689447B1 Cytopathic viruses for therapy and prophylaxis of neoplasia
04/07/1999EP0672182A4 Genomic mismatch scanning.
04/07/1999EP0671471B1 Process for producing foreign protein
04/07/1999EP0654095A4 Electrophoresis of nucleic acid fragments.
04/07/1999EP0642579B1 Improved methods for the preparation of endotoxin-binding proteins
04/07/1999EP0625198B1 Expression of osteogenic factor op-1 in cells of spodoptera frugiperda infected with recombinant baculovirus
04/07/1999EP0605586B1 Process for controlling lepidopteran pests
04/07/1999EP0600868B1 Recombinantly produced lipases for therapeutical treatment
04/07/1999EP0497784B1 Quantitation of nucleic acids using the polymerase chain reaction
04/07/1999CN1213407A Compositions and method for determining anti-viral drug susceptibility and resistance and anti-viral drug screening
04/07/1999CN1213406A Method for inhibiting adenylosuccinate synthetase activity methylthioadenosine phosphorylasse deficient cells
04/07/1999CN1213405A Method for induction of genetic parthenocarpy in plants
04/07/1999CN1213404A Genetic transformation of trees
04/07/1999CN1213403A Polypeptides having mutanase activity and nucleic acids encoding same
04/07/1999CN1213402A Recombinant expression of S-layer proteins
04/07/1999CN1213401A Exodus chemokine materials and method
04/07/1999CN1213380A Peptide immunogens for vaccination against and treatment of allergy
04/07/1999CN1213312A Anticogulant agent useful in treatment of thrombosis
04/07/1999CN1213004A Recombination leukocyte mesonium-2 adenovirus carrier and producing method
04/07/1999CN1213003A 247 position single-mutant enzyme and 138, 247 position double-mutant enzyme of glucose isomerase and configuration method thereof
04/07/1999CN1212967A Parathormone related protein human source antibody and its preparation method
04/07/1999CN1212890A Compositions useful for transferring therapeutically active substances into target cell, and their use in gene therapy
04/07/1999CA2249715A1 Abc transporter
04/06/1999US5892071 Cationic transport reagents
04/06/1999US5892070 Transgenic non-human mammals producing oligosaccharides and glycoconjugates
04/06/1999US5892024 Bifunctional nucleosides, oligomers thereof, and methods of making and using the same
04/06/1999US5892023 Synthetic nucleotide sequences for treatment of allergies by suppression of gene expression of immunoglobulin e receptors in effector cells
04/06/1999US5892020 Multivalent single chain antibodies
04/06/1999US5892019 Production of a single-gene-encoded immunoglobulin
04/06/1999US5892018 Voltage independent, amiloride sensitive, sodium and lithium current, indiscriminant transport protein from human central nervous system; for diagnosis, gene therapy, and treatment of nervous system disorders
04/06/1999US5892015 Human rhombotin-like protein
04/06/1999US5892014 DNA encoding a protease-activated receptor 3
04/06/1999US5892012 Rab Proteins
04/06/1999US5892009 DNA and encoded protein which regulates cold and dehydration regulated genes
04/06/1999US5892004 Method for preparing PACAP receptor protein
04/06/1999US5892003 Ciliary neurotrophic factor receptor antibodies
04/06/1999US5892001 Epithelium-derived T-cell factor antibodies
04/06/1999US5892000 From hybridomas 2g6 and b14; for immunoassay test kit used in diagnosis of athlerosclerosis and diabetes
04/06/1999US5891998 Interleukin-6 receptor agonists
04/06/1999US5891997 Receptor for oncostatin M
04/06/1999US5891996 Humanized and chimeric monoclonal antibodies that recognize epidermal growth factor receptor (EGF-R); diagnostic and therapeutic use
04/06/1999US5891994 Peptides and polypeptides which induce antibodies against hiv-1 tat proteins; for vaccines; diagnosis
04/06/1999US5891991 Aplp1 and aplp2 are candidate genes for late onset familial alzheimer's disease.
04/06/1999US5891859 Method for regulating cold and dehydration regulatory genes in a plant
04/06/1999US5891858 Transforming growth factor alpha, treating prostate cancer
04/06/1999US5891840 Stabilization of somatotropins by modification of cysteine residues utilizing site directed mutagenesis
04/06/1999US5891726 Cereal grains
04/06/1999US5891725 Synthetic antisense oligodeoxynucleotides and pharmaceutical compositions containing them
04/06/1999US5891724 Transfecting cell with hybrid nucleic acid
04/06/1999US5891718 Positive feedback antibiotic controlled eukaryotic expression vectors with single transcription unit of first cistron coding for gene product, second cistron coding for antibiotic controlled activator; gene therapy and gene immunization
04/06/1999US5891716 An isolated nucleic acid comprising a nucleotide sequence encoding a peptide having at least one epitope recognized by a t cell receptor specific for allergen canis familiaris i or ii; medical diagnosis; antiallergens
04/06/1999US5891714 Liposome-antisense oligonucleotide aggregate
04/06/1999US5891710 Hybrid plasmid with a dna fragment that contains a genetic sequence that codes for betaine utilization and a mutation in the chromosomal gene coding for the betaine utilization.
04/06/1999US5891706 Hybridoma cell line; therapy and diagnosis of autoimmune skin disorders, antitumor agents
04/06/1999US5891704 Method to produce high levels of methioninase
04/06/1999US5891703 Mutated penicillin G acylase genes
04/06/1999US5891701 Nucleic acids encoding a polypeptide having protease activity
04/06/1999US5891700 Receptor-type phosphotyrosine phosphatase-γ
04/06/1999US5891699 Mutant hydrolase enzyme that demonstrates significantly improved activity and increase heat resistance; immunoenzymic assays and diagnostic kits
04/06/1999US5891698 Oligosaccharides and glycoproteins produced in milk of transgenic non-human mammals
04/06/1999US5891695 Polypeptides involved in the biosynthesis of streptogramins, nucleotide sequences coding for these polypeptides and their use
04/06/1999US5891694 Method for recovering nucleic acid and device for the same purpose
04/06/1999US5891693 The vectors comprise an active glutamine synthetase (gs) gene as well as a heterologous gene of interest to be expressed.
04/06/1999US5891692 Method for increasing the viability and transformation ability of bacteria during or after storage at low temperatures
04/06/1999US5891691 Method of producing a cell carrying an excess of mammalian centromeres and the cell line carrying an excess of mammalian centromeres
04/06/1999US5891690 A process which reduces the presence of replication competent virus; for large scale production of infectious e1-deleted virions; for gene therapy of cystic fibrosis, duchenne muscular dystrophy; anticarcinogenic
04/06/1999US5891689 Heme-bearing microparticles for targeted delivery of drugs
04/06/1999US5891688 Regulatory protein having single amino acid substitutions creating an active protein not requiring normal phosphorylation; fungicides
04/06/1999US5891687 Positive selection vector based on the caps gene, pCAPs vector and its use
04/06/1999US5891686 Method of production of poly-β-hydroxyalkanoate copolymers
04/06/1999US5891684 Base-modified enzymatic nucleic acid
04/06/1999US5891683 Having enzymatic activity to cleave a target rna molecule, wherein said enzymatic nucleic acid molecule comprises an abasic moiety in a single-stranded region of said enzymatic nucleic acid molecule.
04/06/1999US5891681 Modified promoter for RNA polymerase, its preparation and its applications
04/06/1999US5891680 Dna molecule encoding an active il-12 fusion protein with at least two polypeptide monomers linked by heterologous polypeptide linker; stimulates ifn-alpha production, enhances antitumor immunity and cell mediated immunity
04/06/1999US5891679 TNF-alpha muteins and a process for preparing them
04/06/1999US5891678 Isolated polynucleotide encoding bacterial enzyme involved in mediating protein secretion; treatment of invasive infections and toxigenic diseases; antibiotic screening and development