Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
06/1999
06/08/1999US5910438 For efficient transformation of prokaryotic cells; comprised of promoter and nucleotide sequence coding for fusion protein poison ccdb(control of cell death)
06/08/1999US5910436 Trehalose phosphorylase, its preparation and uses
06/08/1999US5910434 Separately inserting minimal gag-pol and minimal env open reading frames into expression plasmids, inserting plasmids into eukaryotic cells, propagating, screening for the gene expression; gene therapy
06/08/1999US5910433 Keto group-introducing enzyme, DNA coding therefor and method for producing ketocarotenoids
06/08/1999US5910432 Nucleic acid sequence isolated from psuedonocardia thermophila coding for alpha subunit of enzyme; for conversion of nitriles to amides
06/08/1999US5910431 Polynucleotides encoding chemokine α-2
06/08/1999US5910430 Isolated nucleic acid encoding G-protein coupled receptor (HTADX50)
06/08/1999US5910428 Dna which codes for corticotropin-releasing factor binding protein; treating of eating disorders, alcholism; hypertensive agents
06/08/1999US5910427 Protein derivatives formed by replacement, substitution, or chemical modification of amino acids 57 and/or 60 having increased activity; for immunosuppressives/allergy treatments
06/08/1999US5910418 Immunoassay to identify prematurely terminated gene products; diagnosis of familial adenomatous polyposis
06/08/1999US5910417 Controlling allergic inflammation; by administering to humans a compound which interacts with kinase signal tranduction pathway, suppressing cytokine production
06/08/1999US5910416 Adrenomedullin
06/08/1999US5910415 Controlled modification of eukaryotic genomes
06/08/1999US5910414 Diagnosing bacterial infection by screening infected tissue using probes to identify nucleic acid sequences og bacterial enzyme
06/08/1999US5910413 Screening for the allelic forms of human leukocyte antigens in a sample; hybridizing primers to conserved regions of genome and multiplying the allelic forms comparing determined sequences to known alleles
06/08/1999US5910411 Transfecting cell which expresses immediate early gene 86 and reporter gene with polynucleotide coding for agent, evaluating effect on reporter gene transcription
06/08/1999US5910408 Screening population of nucleic acid molecules each with region of random sequence by incubating with substrate and complementary template nucleic acids, isolating active nucleic acids, then amplifying, optionally repeating
06/08/1999US5910407 Diagnosis in mammal of gastrointestinal neoplasm by separating nucleic acid using alkaline buffer with chelating agent at low salt concentration, amplifying, detection of mutation in k-ras oncogene
06/08/1999US5910405 HCV diagnostic agents
06/08/1999US5910310 Genetic engineered antigenic material comprising isolated whole cell culture particles as a vaccine preventing viral diseases
06/08/1999US5910050 Solid matrix conditioning of seeds for sorting purposes
06/08/1999CA2242308A1 Novel compounds
06/08/1999CA1340587C Monoclonal antibodies and vaccine development directed to human cancer-associated antigens by immunization with animal and human mucin and with synthetic carbohydrate-carrier conjugates
06/08/1999CA1340586C Process for recovering microbially produced interferon-beta
06/04/1999CA2253011A1 Dna encoding neospora dihydrofolate reductase-thymidylate synthase
06/03/1999WO1999027138A1 Nucleic acid ligands of tissue target
06/03/1999WO1999027137A1 De novo or 'universal' sequencing array
06/03/1999WO1999027136A1 Decreasing cell proliferation by decreasing levels of pp5
06/03/1999WO1999027135A2 Method for identifying and inhibiting functional nucleic acid molecules in cells
06/03/1999WO1999027134A1 Antisense oligonucleotide modulation of human serine/threonine protein phosphatase gene expression
06/03/1999WO1999027133A1 Improved selex procedure and an anti-cd4 aptamer
06/03/1999WO1999027132A1 Reagents and methods for detecting genes related to major histocompatibility complex of domestic fowl, such as chicken
06/03/1999WO1999027131A2 Topologically fixed matrix bonded nucleic acid molecule
06/03/1999WO1999027129A1 Virulence-associated nucleic acid sequences and uses thereof
06/03/1999WO1999027128A1 ribH
06/03/1999WO1999027127A1 NOVEL ribB
06/03/1999WO1999027126A1 ribG
06/03/1999WO1999027125A1 ribA
06/03/1999WO1999027123A2 Modified sv40 viral vectors
06/03/1999WO1999027122A1 Vectors inhibiting or delaying the binding of an immunodeficiency virus to cells
06/03/1999WO1999027121A1 Development of viruses resistant to inactivation by the human complement system
06/03/1999WO1999027120A1 Methods and means for modification of glucosinolates in plants
06/03/1999WO1999027119A1 Method and compositions useful for the activation of silent transgenes
06/03/1999WO1999027118A1 Conditionally amplifiable bacterial artificial chromosome (bac) vector
06/03/1999WO1999027117A1 Cold-inducible expression vector
06/03/1999WO1999027116A2 Dna molecules conferring dalapon-resistance to plants and plants transformed thereby
06/03/1999WO1999027115A1 A thermophilic alkaline phosphoesterase and its expression
06/03/1999WO1999027114A1 A pathogen and stress-responsive promoter for gene expression
06/03/1999WO1999027113A1 Mouse telomerase reverse transcriptase
06/03/1999WO1999027112A1 Human irak-2, a human interleukin-1 receptor associated kinase-2
06/03/1999WO1999027111A1 Desaturase genes and their use
06/03/1999WO1999027110A1 Hormone-dependent forms of the adeno-associated virus, rep proteins, dna sequences coding for them, vectors containing them, and regulatory methods of their intracellular activity
06/03/1999WO1999027109A2 EXTRACELLULAR MATRIX-BINDING PROTEINS FROM $i(STAPHYLOCOCCUS AUREUS)
06/03/1999WO1999027108A1 Lactose repressor proteins with altered ligand responsivity
06/03/1999WO1999027107A2 Gram-positive microorganism formate transporters
06/03/1999WO1999027106A1 NOVEL guaA
06/03/1999WO1999027105A2 Chlamydia pneumoniae genomic sequence and polypeptides, fragments thereof and uses thereof, in particular for the diagnosis, prevention and treatment of infection
06/03/1999WO1999027104A1 Histamine and serotonin binding molecules
06/03/1999WO1999027103A1 Mammalian cytokine-like polypeptide-10
06/03/1999WO1999027102A1 Cd4+ t-lymphocyte protease genes and inhibitors thereof
06/03/1999WO1999027101A1 Method for preparing adenovirus vectors, vectors so prepared, and uses thereof
06/03/1999WO1999027100A1 Fibroblast growth factor-19
06/03/1999WO1999027099A1 Orf, a substrate for extracellular signal-regulated kinase, erk-6, and related methods
06/03/1999WO1999027098A2 A-33 related antigens and their pharmacological uses
06/03/1999WO1999027097A2 CLONING OF A TETRODOTOXIN-RESISTANT SODIUM CHANNEL α-SUBUNIT
06/03/1999WO1999027096A1 A NOVEL EGF MOTIF PROTEIN OBTAINED FROM A cDNA LIBRARY OF FETAL LIVER-SPLEEN
06/03/1999WO1999027095A1 Human cdc10 homolog
06/03/1999WO1999027094A2 HUMAN PROTEINS HAVING TRANSMEMBRANE DOMAINS AND DNAs ENCODING THESE PROTEINS
06/03/1999WO1999027093A2 The nip3 family of proteins
06/03/1999WO1999027092A1 Purified transcription factor cdf-1 and its use
06/03/1999WO1999027091A1 Dp transcription factor-interacting protein and its use
06/03/1999WO1999027090A1 Methods for identifying the toxic/pathologic effect of environmental stimuli on gene transcription
06/03/1999WO1999027089A1 A gene called xlis and the xlis gene product, called doublecortin and their preparations
06/03/1999WO1999027088A2 Novel gene and protein expressed in neural and pancreatic tissues
06/03/1999WO1999027087A1 Antisense oligonucleotides specific for cdk4
06/03/1999WO1999027086A1 Chimeric antisense oligonucleotides against tnf-alpha and their uses
06/03/1999WO1999027085A2 Method of parallel screening for insertion mutants and a kit to perform this method
06/03/1999WO1999027084A1 Novel pectate lyases
06/03/1999WO1999027082A1 Protease variants and compositions
06/03/1999WO1999027081A2 Alpha/beta hydrolase-fold enzymes
06/03/1999WO1999027080A2 Human protein kinase and kinase inhibitors
06/03/1999WO1999027079A1 Secreted proteins and polynucleotides encoding them
06/03/1999WO1999027078A1 Chemokine alpha-5
06/03/1999WO1999027074A1 Novel tig
06/03/1999WO1999027073A1 deoD
06/03/1999WO1999027072A1 Reagents and methods for diversification of dna
06/03/1999WO1999027020A1 Dibenzorhodamine dyes useful as flourescent labelling agents
06/03/1999WO1999026978A1 Signal sequence trapping method
06/03/1999WO1999026977A1 Novel receptors opg-2
06/03/1999WO1999026976A1 Tnf ligand family gene
06/03/1999WO1999026975A2 Method for obtaining biologically active dimers of recombinant human growth factors from the cysteine knot family, use of dimers thus obtained
06/03/1999WO1999026973A1 Secreted proteins and polynucleotides encoding them
06/03/1999WO1999026972A1 Secreted proteins and polynucleotides encoding them
06/03/1999WO1999026970A1 NOVEL pth
06/03/1999WO1999026967A1 Secreted proteins and polynucleotides encoding them
06/03/1999WO1999026961A1 Secreted proteins and polynucleotides encoding them
06/03/1999WO1999026959A1 NOVEL recJ
06/03/1999WO1999026664A1 Recombinant mycoplasma hyopneumoniae vaccine
06/03/1999WO1999026663A2 Treatment of cancer using cytokine-expressing polynucleotides and compositions therefor
06/03/1999WO1999026656A1 Monoclonal human natural antibodies