Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210) |
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06/08/1999 | US5910438 For efficient transformation of prokaryotic cells; comprised of promoter and nucleotide sequence coding for fusion protein poison ccdb(control of cell death) |
06/08/1999 | US5910436 Trehalose phosphorylase, its preparation and uses |
06/08/1999 | US5910434 Separately inserting minimal gag-pol and minimal env open reading frames into expression plasmids, inserting plasmids into eukaryotic cells, propagating, screening for the gene expression; gene therapy |
06/08/1999 | US5910433 Keto group-introducing enzyme, DNA coding therefor and method for producing ketocarotenoids |
06/08/1999 | US5910432 Nucleic acid sequence isolated from psuedonocardia thermophila coding for alpha subunit of enzyme; for conversion of nitriles to amides |
06/08/1999 | US5910431 Polynucleotides encoding chemokine α-2 |
06/08/1999 | US5910430 Isolated nucleic acid encoding G-protein coupled receptor (HTADX50) |
06/08/1999 | US5910428 Dna which codes for corticotropin-releasing factor binding protein; treating of eating disorders, alcholism; hypertensive agents |
06/08/1999 | US5910427 Protein derivatives formed by replacement, substitution, or chemical modification of amino acids 57 and/or 60 having increased activity; for immunosuppressives/allergy treatments |
06/08/1999 | US5910418 Immunoassay to identify prematurely terminated gene products; diagnosis of familial adenomatous polyposis |
06/08/1999 | US5910417 Controlling allergic inflammation; by administering to humans a compound which interacts with kinase signal tranduction pathway, suppressing cytokine production |
06/08/1999 | US5910416 Adrenomedullin |
06/08/1999 | US5910415 Controlled modification of eukaryotic genomes |
06/08/1999 | US5910414 Diagnosing bacterial infection by screening infected tissue using probes to identify nucleic acid sequences og bacterial enzyme |
06/08/1999 | US5910413 Screening for the allelic forms of human leukocyte antigens in a sample; hybridizing primers to conserved regions of genome and multiplying the allelic forms comparing determined sequences to known alleles |
06/08/1999 | US5910411 Transfecting cell which expresses immediate early gene 86 and reporter gene with polynucleotide coding for agent, evaluating effect on reporter gene transcription |
06/08/1999 | US5910408 Screening population of nucleic acid molecules each with region of random sequence by incubating with substrate and complementary template nucleic acids, isolating active nucleic acids, then amplifying, optionally repeating |
06/08/1999 | US5910407 Diagnosis in mammal of gastrointestinal neoplasm by separating nucleic acid using alkaline buffer with chelating agent at low salt concentration, amplifying, detection of mutation in k-ras oncogene |
06/08/1999 | US5910405 HCV diagnostic agents |
06/08/1999 | US5910310 Genetic engineered antigenic material comprising isolated whole cell culture particles as a vaccine preventing viral diseases |
06/08/1999 | US5910050 Solid matrix conditioning of seeds for sorting purposes |
06/08/1999 | CA2242308A1 Novel compounds |
06/08/1999 | CA1340587C Monoclonal antibodies and vaccine development directed to human cancer-associated antigens by immunization with animal and human mucin and with synthetic carbohydrate-carrier conjugates |
06/08/1999 | CA1340586C Process for recovering microbially produced interferon-beta |
06/04/1999 | CA2253011A1 Dna encoding neospora dihydrofolate reductase-thymidylate synthase |
06/03/1999 | WO1999027138A1 Nucleic acid ligands of tissue target |
06/03/1999 | WO1999027137A1 De novo or 'universal' sequencing array |
06/03/1999 | WO1999027136A1 Decreasing cell proliferation by decreasing levels of pp5 |
06/03/1999 | WO1999027135A2 Method for identifying and inhibiting functional nucleic acid molecules in cells |
06/03/1999 | WO1999027134A1 Antisense oligonucleotide modulation of human serine/threonine protein phosphatase gene expression |
06/03/1999 | WO1999027133A1 Improved selex procedure and an anti-cd4 aptamer |
06/03/1999 | WO1999027132A1 Reagents and methods for detecting genes related to major histocompatibility complex of domestic fowl, such as chicken |
06/03/1999 | WO1999027131A2 Topologically fixed matrix bonded nucleic acid molecule |
06/03/1999 | WO1999027129A1 Virulence-associated nucleic acid sequences and uses thereof |
06/03/1999 | WO1999027128A1 ribH |
06/03/1999 | WO1999027127A1 NOVEL ribB |
06/03/1999 | WO1999027126A1 ribG |
06/03/1999 | WO1999027125A1 ribA |
06/03/1999 | WO1999027123A2 Modified sv40 viral vectors |
06/03/1999 | WO1999027122A1 Vectors inhibiting or delaying the binding of an immunodeficiency virus to cells |
06/03/1999 | WO1999027121A1 Development of viruses resistant to inactivation by the human complement system |
06/03/1999 | WO1999027120A1 Methods and means for modification of glucosinolates in plants |
06/03/1999 | WO1999027119A1 Method and compositions useful for the activation of silent transgenes |
06/03/1999 | WO1999027118A1 Conditionally amplifiable bacterial artificial chromosome (bac) vector |
06/03/1999 | WO1999027117A1 Cold-inducible expression vector |
06/03/1999 | WO1999027116A2 Dna molecules conferring dalapon-resistance to plants and plants transformed thereby |
06/03/1999 | WO1999027115A1 A thermophilic alkaline phosphoesterase and its expression |
06/03/1999 | WO1999027114A1 A pathogen and stress-responsive promoter for gene expression |
06/03/1999 | WO1999027113A1 Mouse telomerase reverse transcriptase |
06/03/1999 | WO1999027112A1 Human irak-2, a human interleukin-1 receptor associated kinase-2 |
06/03/1999 | WO1999027111A1 Desaturase genes and their use |
06/03/1999 | WO1999027110A1 Hormone-dependent forms of the adeno-associated virus, rep proteins, dna sequences coding for them, vectors containing them, and regulatory methods of their intracellular activity |
06/03/1999 | WO1999027109A2 EXTRACELLULAR MATRIX-BINDING PROTEINS FROM $i(STAPHYLOCOCCUS AUREUS) |
06/03/1999 | WO1999027108A1 Lactose repressor proteins with altered ligand responsivity |
06/03/1999 | WO1999027107A2 Gram-positive microorganism formate transporters |
06/03/1999 | WO1999027106A1 NOVEL guaA |
06/03/1999 | WO1999027105A2 Chlamydia pneumoniae genomic sequence and polypeptides, fragments thereof and uses thereof, in particular for the diagnosis, prevention and treatment of infection |
06/03/1999 | WO1999027104A1 Histamine and serotonin binding molecules |
06/03/1999 | WO1999027103A1 Mammalian cytokine-like polypeptide-10 |
06/03/1999 | WO1999027102A1 Cd4+ t-lymphocyte protease genes and inhibitors thereof |
06/03/1999 | WO1999027101A1 Method for preparing adenovirus vectors, vectors so prepared, and uses thereof |
06/03/1999 | WO1999027100A1 Fibroblast growth factor-19 |
06/03/1999 | WO1999027099A1 Orf, a substrate for extracellular signal-regulated kinase, erk-6, and related methods |
06/03/1999 | WO1999027098A2 A-33 related antigens and their pharmacological uses |
06/03/1999 | WO1999027097A2 CLONING OF A TETRODOTOXIN-RESISTANT SODIUM CHANNEL α-SUBUNIT |
06/03/1999 | WO1999027096A1 A NOVEL EGF MOTIF PROTEIN OBTAINED FROM A cDNA LIBRARY OF FETAL LIVER-SPLEEN |
06/03/1999 | WO1999027095A1 Human cdc10 homolog |
06/03/1999 | WO1999027094A2 HUMAN PROTEINS HAVING TRANSMEMBRANE DOMAINS AND DNAs ENCODING THESE PROTEINS |
06/03/1999 | WO1999027093A2 The nip3 family of proteins |
06/03/1999 | WO1999027092A1 Purified transcription factor cdf-1 and its use |
06/03/1999 | WO1999027091A1 Dp transcription factor-interacting protein and its use |
06/03/1999 | WO1999027090A1 Methods for identifying the toxic/pathologic effect of environmental stimuli on gene transcription |
06/03/1999 | WO1999027089A1 A gene called xlis and the xlis gene product, called doublecortin and their preparations |
06/03/1999 | WO1999027088A2 Novel gene and protein expressed in neural and pancreatic tissues |
06/03/1999 | WO1999027087A1 Antisense oligonucleotides specific for cdk4 |
06/03/1999 | WO1999027086A1 Chimeric antisense oligonucleotides against tnf-alpha and their uses |
06/03/1999 | WO1999027085A2 Method of parallel screening for insertion mutants and a kit to perform this method |
06/03/1999 | WO1999027084A1 Novel pectate lyases |
06/03/1999 | WO1999027082A1 Protease variants and compositions |
06/03/1999 | WO1999027081A2 Alpha/beta hydrolase-fold enzymes |
06/03/1999 | WO1999027080A2 Human protein kinase and kinase inhibitors |
06/03/1999 | WO1999027079A1 Secreted proteins and polynucleotides encoding them |
06/03/1999 | WO1999027078A1 Chemokine alpha-5 |
06/03/1999 | WO1999027074A1 Novel tig |
06/03/1999 | WO1999027073A1 deoD |
06/03/1999 | WO1999027072A1 Reagents and methods for diversification of dna |
06/03/1999 | WO1999027020A1 Dibenzorhodamine dyes useful as flourescent labelling agents |
06/03/1999 | WO1999026978A1 Signal sequence trapping method |
06/03/1999 | WO1999026977A1 Novel receptors opg-2 |
06/03/1999 | WO1999026976A1 Tnf ligand family gene |
06/03/1999 | WO1999026975A2 Method for obtaining biologically active dimers of recombinant human growth factors from the cysteine knot family, use of dimers thus obtained |
06/03/1999 | WO1999026973A1 Secreted proteins and polynucleotides encoding them |
06/03/1999 | WO1999026972A1 Secreted proteins and polynucleotides encoding them |
06/03/1999 | WO1999026970A1 NOVEL pth |
06/03/1999 | WO1999026967A1 Secreted proteins and polynucleotides encoding them |
06/03/1999 | WO1999026961A1 Secreted proteins and polynucleotides encoding them |
06/03/1999 | WO1999026959A1 NOVEL recJ |
06/03/1999 | WO1999026664A1 Recombinant mycoplasma hyopneumoniae vaccine |
06/03/1999 | WO1999026663A2 Treatment of cancer using cytokine-expressing polynucleotides and compositions therefor |
06/03/1999 | WO1999026656A1 Monoclonal human natural antibodies |