Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
08/1999
08/24/1999US5942607 B7-2: a CTLA4/CD28 ligand
08/24/1999US5942602 Growth factor receptor antibodies
08/24/1999US5942496 Methods and compositions for multiple gene transfer into bone cells
08/24/1999US5942490 Cell death regulators
08/24/1999US5942488 Mutant human beta-globin modified to contain at leaset two non-wild type amino acid residues; enhanced bicarbonate effect
08/24/1999US5942435 Isolating and purifying embryonic stem cells by culturing dissociated cells from swine embryos in stem cell medium absent of a feeder layer, then subculturing to obtain a culture with morphological features of embryonic stem cells
08/24/1999US5942434 Regulatory sequence from phophoglycerate kinase operably linked to coding sequence of exogenous gene; for gene therapy; in situ expression of enzymes which convert prodrugs to active anticarcinogenic/antitumor drugs or cytokines
08/24/1999US5942433 Dna coding for a nucleic acid binding protein with n-terminal modified by addition of acidic amino acids forming domain for stable dimerization or multimerization with cell proteins; for controlling transcription factors by gene therapy
08/24/1999US5942432 A polymerase chain reaction amplification aparatus; which uniformly cycles samples between two temperatures using fluid jets which impinge pressurized fluid against walls ans outlets which vent out fluid
08/24/1999US5942431 DNA sequences encoding lipases and method for producing lipases
08/24/1999US5942430 Esterases
08/24/1999US5942429 DEAH-box proteins
08/24/1999US5942427 N-acetylmannosamine dehydrogenase gene and novel recombinant DNA as well as a method for production of N-acetylmannosamine dehydrogenase
08/24/1999US5942425 Subjecting a sample of disrupted cells to sufficient agitation in the presence of particles to separate nucleic acids from other cellular components; heat lysis without other lysogenic agents or conditions is the preferred method
08/24/1999US5942422 Method for generating a directed, recombinant fusion nucleic acid
08/24/1999US5942421 Culturing non-leaky cells containing gene and phosphate starvation inducible promoter, inducing protein expression preventing complete formation of outer membranes, allowing protein releases
08/24/1999US5942419 RsbW-1 encoding nucleic acids
08/24/1999US5942418 Hydrids; culture product
08/24/1999US5942417 CD44-like protein and nucleic acids
08/24/1999US5942416 Treatment of infections from bacteria using polypeptides and polynucleotides
08/24/1999US5942414 Polynucleotides encoding human G-protein coupled receptor HIBEF51
08/24/1999US5942413 Polynucleotide fragment that codes an antigen from parasitic worms; antihelmintics
08/24/1999US5942412 Polynucleic acid encoding variant insulin-like growth factor I receptor beta subunit and receptor
08/24/1999US5942411 Process of producing B-lactam antibiotics applying microorganisms with increased ligase activity
08/24/1999US5942409 Process for identification of substances modulating ureI dependent mechanisms of Helicobacter pylori metabolism
08/24/1999US5942405 Identifying compounds which inhibit complement receptors by mixing cells expressing surface complement receptors with a labeled compound capable of binding receptor and determining if compound inhibits interactions by signal generation
08/24/1999US5942404 Diagnosing leukemia by incubating cells with specific antibodies and detecting surface antigens
08/24/1999US5942403 Compounds and methods for the detection of t. cruzi infection
08/24/1999US5942401 An in vitro assay detecting the presence of cytotoxic t-cell response to rev and or tat proteins
08/24/1999US5942400 Assays for detecting β-secretase
08/24/1999US5942395 Hybrid ribozymes and methods of use
08/24/1999US5942393 Method for the detection of the presence or absence of methylthioadenosine phosphorylase (MTASE) in a cell sample by detection of the presence or absence of MTASE encoding nucleic acid in the cell sample
08/24/1999US5942392 Genetic markers used jointly for the diagnosis of Alzheimer's disease, and diagnostic method and kit
08/24/1999US5942391 Detecting target nucleic acid from pathogenic microorganisms or viruses by hybridizing nucleic acid to capture probes in the presence of ligand coated magnetic beads forming a complex of the target nucleic acid, beads and probe
08/24/1999US5942389 Developing a genetic suppressor protein with resistance to platinum-based cytotoxic drugs; synthesizing random cdna fragments, transferring dna into expression vector, transducing eukaryotic cells and isolating modified cells
08/24/1999US5942385 Method for molecular diagnosis of tumor angiogenesis and metastasis
08/24/1999US5942254 An infant milk formulas that have some of the advantageous properties of human milk and avoid the disadvantages with bovine milk such as allergic reactions and incomplete digestion, including a biosynthetic human milk proteins
08/24/1999US5942236 Potential vaccine for use against lyme disease to induce a protective immune response in humans by administrating a purified immunogenic outer surface lipoprotein of micelle form
08/24/1999US5942235 Exogenous dna encoding an antigenic determinant of a pathogen; recombinant viruses and gene products are useful for cancer therapy
08/24/1999US5942234 Hepatitis C virus asialoglycoproteins
08/24/1999US5942228 An amino acid sequence protein for the manufacture of complex carbohydrates and as a target for screening of small molecule antagonists of enzyme activity; treating diseases of cellular fucosylation
08/24/1999US5942223 Antiviral therapy using ovine or bovine interferon-tau
08/24/1999US5942221 Recombinant primate granulocyte macrophage-colony stimulating factor
08/24/1999CA2248972A1 Novel compounds
08/24/1999CA2082044C Modulation of gene expression through interference with rna secondary structure
08/24/1999CA1340715C Bovine interleukin-1b
08/24/1999CA1340714C Plant structural gene expression
08/24/1999CA1340713C Plant gene expression
08/20/1999CA2261183A1 Adenoviral transfer vector for the gene transport of a dna sequence
08/20/1999CA2249653A1 Novel compounds
08/19/1999WO1999041608A2 Interaction between cyclin d1 and steroid receptor co-activators
08/19/1999WO1999041584A2 METHODS FOR PREDICTING PREGNANCY OUTCOME IN A SUBJECT BY hCG ASSAY
08/19/1999WO1999041416A2 Compositions comprising viruses and methods for concentrating virus preparations
08/19/1999WO1999041415A1 Transposable element-anchored, amplification method for isolation and identification of tagged genes
08/19/1999WO1999041412A1 A novel npg-1 gene that is differentially expressed in prostate tumors
08/19/1999WO1999041411A2 Method for diagnosis and treatment of disorders of carbohydrate metabolism
08/19/1999WO1999041410A1 Methods for dna amplification and sequencing
08/19/1999WO1999041407A1 Method for developing a pharmaceutical active ingredient
08/19/1999WO1999041406A1 Telomerase assay of body fluids for cancer screening and assessment of disease stage and prognosis
08/19/1999WO1999041404A2 Novel means and methods for the preparation and activation of nucleoside and nucleotide based drugs
08/19/1999WO1999041403A1 Compositions for receptor/liposome mediated transfection and methods of using same
08/19/1999WO1999041402A2 Targeting of genetic vaccine vectors
08/19/1999WO1999041401A1 Method and apparatus for introducing substances into the cell plasma membrane and/or cytosol
08/19/1999WO1999041400A1 Methods for pseudoadenoviral vector production
08/19/1999WO1999041399A1 Methods for purified aav vector production
08/19/1999WO1999041398A1 Vectors, cells and methods for the production of deleterious viral eukaryotic gene transfer vectors
08/19/1999WO1999041397A1 Anti-viral vectors
08/19/1999WO1999041396A1 Use of negative regulation elements for nerve-specific expression of transgenes
08/19/1999WO1999041395A1 Methods and compositions for producing plants and microorganisms that express feedback insensitive threonine dehydratase deaminase
08/19/1999WO1999041394A1 Nucleotide sequences encoding maize rad51
08/19/1999WO1999041393A1 Insecticidal peptides
08/19/1999WO1999041392A1 Nucleic acid comprising the sequence of a promoter inductible by stress and a gene sequence coding for a stilbene synthase
08/19/1999WO1999041391A1 Promoter inductible in plants, sequence incorporating same and resulting product
08/19/1999WO1999041390A2 Expression vector for the production of dead proteins
08/19/1999WO1999041389A1 Streptomyces avermitilis gene directing the ratio of b2:b1 avermectins
08/19/1999WO1999041388A2 Metalloprotease-disintegrins svph3-13 and svph3-17 dna and polypeptides
08/19/1999WO1999041387A2 Prostate-associated serine protease
08/19/1999WO1999041386A2 Novel endo-xylogalacturonase
08/19/1999WO1999041385A1 Mekk1 proteins and fragments thereof for use in regulating apoptosis
08/19/1999WO1999041384A1 Splice variants of p101 protein
08/19/1999WO1999041383A1 Antigen library immunization
08/19/1999WO1999041382A2 A novel interleukin-3 and uses thereof
08/19/1999WO1999041381A1 Neuroserpin
08/19/1999WO1999041380A1 THE REGULATORY SEQUENCE OF η-4 GERMLINE (GL) TRANSCRIPT AND ITS APPLICATIONS
08/19/1999WO1999041379A2 Members of the d52 gene family
08/19/1999WO1999041378A1 Members of the d52 gene family
08/19/1999WO1999041377A1 Novel cystine knot protein and materials and methods for making it
08/19/1999WO1999041376A2 Retinoblastoma protein complexes and retinoblastoma interacting proteins
08/19/1999WO1999041375A2 Human receptor proteins
08/19/1999WO1999041374A2 Human short-chain tnf-receptor family protein
08/19/1999WO1999041373A2 Human transport-associated molecules
08/19/1999WO1999041372A1 Potassium channel polypeptide
08/19/1999WO1999041371A1 Use of ribozymes for functionating genes
08/19/1999WO1999041370A1 Cea/nca-based differentiation cancer therapy
08/19/1999WO1999041369A2 Genetic vaccine vector engineering
08/19/1999WO1999041368A2 Optimization of immunomodulatory properties of genetic vaccines
08/19/1999WO1999041367A1 Heteroaromatic oligoamides as affinity ligands
08/19/1999WO1999041365A1 H2-o modified transgenic animals
08/19/1999WO1999041364A2 Compositions and methods for wound healing
08/19/1999WO1999041363A1 Podocalyxin like sialomucins having selectin ligand activity