| Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210) |
|---|
| 01/25/2000 | US6018019 Immunogenic synthetic peptides which are useful alone or in conjugates in vaccines against hemophilus influenza infection |
| 01/25/2000 | US6017898 Inhibition of tumor growth by antisense oligonucleotides for IL-8 and IL-8 receptor |
| 01/25/2000 | US6017885 IGF/IGFBP complex for promoting bone formation and for regulating bone remodeling |
| 01/25/2000 | US6017882 Modified vitamin K-dependent polypeptides |
| 01/25/2000 | US6017871 Protease-containing cleaning compositions |
| 01/25/2000 | US6017870 From fermentation of trichoderma |
| 01/25/2000 | US6017866 Lipases with improved surfactant resistance |
| 01/25/2000 | US6017763 G-beta-gamma regulated phosphatidylinositol-3' kinase |
| 01/25/2000 | US6017762 An ascomycetes fungus strain transformed with a cassette for expressing an aspartic protease precursor; production of cooked cheeses |
| 01/25/2000 | US6017761 Isolating nucleic acid sequence encoding a minimal open reading frame and inserting into a plasmid, then transformed into eukaryotic cells that are free of endogenous retroviral nucleic acid, producing recombinant retroviral cells |
| 01/25/2000 | US6017759 Chimeric infectious bursal disease virus cDNA clones, expression products and vaccines based thereon |
| 01/25/2000 | US6017758 DMNPE caged nucleic acid and vector |
| 01/25/2000 | US6017757 A homogenous cell population of parasitic cells obtained by in-vitro culturing of differentiated intestinal cells of a nematode; therapy and prevention of parasitic infections in animals |
| 01/25/2000 | US6017756 A catalytic rna enzyme, or ribozyme; therapy for hepatitis b |
| 01/25/2000 | US6017755 MADR2 tumour suppressor gene |
| 01/25/2000 | US6017754 Eukaryotic expression vector of linked dna sequences encoding anti-4-ethoxymethylene-2-phenyl-2-oxazolin-5-one single-chain antibody, transmembrane domain, signal sequence, and protein; screening of cell cultures within hours of transfection |
| 01/25/2000 | US6017749 A biological culture capable of producing protease, xylanse and cellulase |
| 01/25/2000 | US6017748 Cloning host organisms |
| 01/25/2000 | US6017745 Enzyme amplification and purification process for producing DNA polymerase |
| 01/25/2000 | US6017744 Human N-acetyl transferase |
| 01/25/2000 | US6017743 Dna which codes for a glycosyltransferase which adds oligosialic acids to glycoproteins and glycolipids; for anticarcinogenic/antimetastasis/antiinflammatory agents; for maturation of sperm and reactivation of nervous tissues |
| 01/25/2000 | US6017742 Immobilization of biologically active substances on a carrier containing a carbodiimide group-containing polymer |
| 01/25/2000 | US6017739 Amplifying the normal nucleic acid and the mutant nucleic acid in the sample, and a labeled nucleic acid standard comprising an amplification label capable of bindidng to a solid support, then mixing together samples allowing competitive |
| 01/25/2000 | US6017737 E. coli msDNA synthesizing system, products and uses |
| 01/25/2000 | US6017735 A fusion polypeptide having a herpes virus virion protein and a second protein selected from cell cycle control, suicide protein, antigenic sequences, immunomodulating or therapeutic protein; antiproliferative/anticarcinogenic agents |
| 01/25/2000 | US6017734 A hydrophobic nucleic acid sequence that targets the nuclear envelope polypeptides of heterologous cellular membrane proteins; insecticides |
| 01/25/2000 | US6017733 Impaired dominant selectable marker sequence and intronic insertion strategies for enhancement of expression of gene product and expression vector systems comprising same |
| 01/25/2000 | US6017732 To screen for enhanced specfic binding pair binding |
| 01/25/2000 | US6017731 Nucleotide sequences encoding a signal sequence, a propeptide leader sequence, a preferred processing site cleaved in situ by a yeast proteolytic enzyme; expressing mammalian proteins and their secretion in a biologically active mature form |
| 01/25/2000 | US6017730 Method of limiting the survival of genetically engineered microorganisms in their environment |
| 01/25/2000 | US6017729 Receptor activator of NF-κB |
| 01/25/2000 | US6017728 ribH |
| 01/25/2000 | US6017727 Syndecan enhancer element and syndecan stimulation of cellular differentiation |
| 01/25/2000 | US6017726 Efficient process for producing 7-aminodeacetyl-cephalosoporanic acid by culturing penicillium chrysogenum with adipic acid, salt or ester to produce adipoyl-6-aminopenicillanic acid, then enzymatically altering molecule |
| 01/25/2000 | US6017719 Targeting cells from heterogeneous suspension; forming cell complexes linked to antibody bound to surface antigen, separating complexes, mixing antibody with peptide that binds and displaces antibody from antigen, releasing target cell |
| 01/25/2000 | US6017716 Mixing biological sample with an isolated protein and determining binding of antibodies in sample to protein; antibody binding idicates melanoma |
| 01/25/2000 | US6017714 Netrins |
| 01/25/2000 | US6017710 A nucleic acid molecule that codes for a g-protein polypeptide; diagnosis and therapy; anticarcinogenic and antitumor agents |
| 01/25/2000 | US6017708 Human Myt1 protein and chimeric proteins derived therefrom |
| 01/25/2000 | US6017705 Nucleic acid molecules that codes for tumor rejection antigens; diagnosis and screening for possible presence of lymphoma, or head and neck squamous cell carcinoma, skin and mammary carcinomas |
| 01/25/2000 | US6017704 Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids |
| 01/25/2000 | US6017702 Sanger sequencing which reduces variability of peak heights in generated electropherogram |
| 01/25/2000 | US6017700 Cationic oligonucleotides, and related methods of synthesis and use |
| 01/25/2000 | US6017697 Excitatory amino acid receptor protein and related nucleic acid compounds |
| 01/25/2000 | US6017696 Controlling nucleic acid hybridization by connecting multiple electrical sources to several location where a plurality of nucleic acids with target nucleic acids are attached, apply a negative potential, removing non specific nucleic acid |
| 01/25/2000 | US6017695 A polynucleotide sequence that encodes a human brain glycoprotein, contactin; to study signal transmissions, cell morphology, cell metabolism and cell adhesion |
| 01/25/2000 | US6017692 Methods of detecting a malignant cell in a biological sample comprising measuring Mxi gene expression alterations |
| 01/25/2000 | US6017542 Nucleotide and amino acid sequences of canine herpesvirus GD and uses therefor |
| 01/25/2000 | US6017539 Multimeric hybrid genes encoding corresponding chimeric protein comprise gene sequence coding for antigenic region of protein from first pathogen linked to gene sequence coding for antigenic region of protein from second pathogen |
| 01/25/2000 | US6017538 Plasmodium falciparum antigens inducing protective antibodies |
| 01/25/2000 | US6017535 cDNA sequence of Dengue virus serotype 1 (Singapore strain) |
| 01/25/2000 | US6017534 Development of transgenic plants which express broad-spectrum insecticidal activity against a variety of flies, moths and beetles; chimeric crystal delta-endotoxins having improved insecticidal properties and broad-range specificities |
| 01/25/2000 | US6017531 An extracellular neutral protease and a stabilizer of glyceryl cocoate as a wound healing agent and for debriding necrotic tissue; storage stable enzyme activity at room temperature; burns; cutaneous ulcers; pressure necroses incisional, |
| 01/25/2000 | US6017530 Promoting the growth of a monogastric or polygastric animal and efficiecy of fat digestion |
| 01/25/2000 | US6017529 A purified human spermidine/spermine n1-acetyltransferase comprising the amino acid sequence of seq id no:1; diagnostic assays; prevention and treatment of cancer |
| 01/25/2000 | US6017524 Inhibiting the growth p53 deficient tumor cells by administering the p53 gene |
| 01/25/2000 | US6017523 Treating a immunodeficiency, hematopoietic or bone marrow disorder ;stimulants; anticarcinogenic agents; side effect reduction; muteins having several variations, preferably in one to three amino acids |
| 01/25/2000 | US6017457 Matched ion polynucleotide chromatography which enhances the separation of polynucleotides; extending the maximum useful life of a chromatographic separation column by protecting the column from the multivalent cation contamination |
| 01/25/2000 | CA2145859C Bacillus thuringiensis cryet4 and cryet5 toxin genes and proteins toxic to lepidopteran insects |
| 01/25/2000 | CA2113412C Transgenic plants producing polyhydroxyalkanoates |
| 01/25/2000 | CA2031504C Monoclonal antibodies to c-reactive protein |
| 01/25/2000 | CA2003508C Monodisperse superparamagnetic particles for use in nucleic acid analyses |
| 01/25/2000 | CA1340881C Nucleic acid probes for detecting human papillomavirus |
| 01/25/2000 | CA1340880C Cancer-related antigen-specific human immunoglobulins and human/human hybridomas having the ability to produce said human immunoglobulins |
| 01/25/2000 | CA1340879C Recombinant dna product and methods |
| 01/25/2000 | CA1340878C Production of human t-cell leukemia (lymphotropic) retrovirus (htlv-i) envelope protein fragments in bacteria and use in seroepidemiological survey of human lymphoid malignancies |
| 01/20/2000 | WO2000003248A1 Method for identifying a presenilinase inhibitor |
| 01/20/2000 | WO2000003244A2 Immortalized human keratinocyte cell line |
| 01/20/2000 | WO2000003038A2 Method and reagents for analyzing the nucleotide sequence of nucleic acids |
| 01/20/2000 | WO2000003036A1 Method of screening for potential anti-metastatic and anti-inflammatory agents using mammalian heparanase as a probe |
| 01/20/2000 | WO2000003030A2 Recombinant raccoonpox virus and uses thereof as a vaccine in mammalian and avian species |
| 01/20/2000 | WO2000003029A2 Chimaeric adenoviruses |
| 01/20/2000 | WO2000003028A2 Method for optimizing the production of adenovirus vectors |
| 01/20/2000 | WO2000003027A1 Method for improving the gene transfer of genetic material in mammalian cells through the use of p21 (waf-1) |
| 01/20/2000 | WO2000003026A2 Transcription coactivators |
| 01/20/2000 | WO2000003025A2 Method of genetic modification of a wild type viral sequence |
| 01/20/2000 | WO2000003024A2 Alleles of the human mu opioid receptor, diagnostic methods using said alleles, and methods of treatment based thereon |
| 01/20/2000 | WO2000003023A1 Usurpin, a mammalian ded-caspase homologue that precludes caspase-8 recruitment and activation by the cd-95 (fas, apo-1) receptor complex |
| 01/20/2000 | WO2000003022A2 Expression of herbicide tolerance genes in plant plastids |
| 01/20/2000 | WO2000003019A1 Conditional mutants of influenza virus m2 protein |
| 01/20/2000 | WO2000003018A2 Antibiotic protein and method of production |
| 01/20/2000 | WO2000003017A2 Enhancer elements for increased translation in plant plastids |
| 01/20/2000 | WO2000003016A1 Immunological reagent specifically interacting with the extracellular domain of the human zeta chain |
| 01/20/2000 | WO2000003015A2 Human transport protein homologs |
| 01/20/2000 | WO2000003014A1 Pharmaceutical uses of nab1 and nab2 |
| 01/20/2000 | WO2000003013A2 Gene and protein involved in liver regeneration |
| 01/20/2000 | WO2000003012A2 Expression of eukaryotic peptides in plant plastids |
| 01/20/2000 | WO2000003011A2 METHOD FOR PRODUCING A PEPTIDE WITH A pI ABOVE 8 OR BELOW 5 |
| 01/20/2000 | WO2000003010A2 Protein secretion from bacteria having reduced expression of a product encoded by the dlt operon |
| 01/20/2000 | WO2000003009A2 Genes for the biosynthesis of anticapsin and bacilysine, their isolation and their use |
| 01/20/2000 | WO2000003008A2 Recombinant haploid or diploid yarrowia lipolytica cells for the functional heterologous expression of cytochrome p450 systems |
| 01/20/2000 | WO2000003006A1 Sucrose biosynthesis genes and uses therefor |
| 01/20/2000 | WO2000003004A2 Presenilin 2 specific ribozyme |
| 01/20/2000 | WO2000002997A2 Transgenic mouse expressing green fluorescent protein in astrocytes |
| 01/20/2000 | WO2000002996A2 Recombinant constructs and systems for secretion of proteins via type iii secretion systems |
| 01/20/2000 | WO2000002950A1 Polyester analogue of poly-l-lysine as a soluble, biodegradable gene delivery carrier |
| 01/20/2000 | WO2000002925A1 Lupus anticoagulant antibody to f1 region of prothrombin |
| 01/20/2000 | WO2000002922A1 Antibody against protein tyrosine phosphatase intracellular domains |
| 01/20/2000 | WO2000002919A1 Growth hormone secretagogue related receptors and nucleic acids |
| 01/20/2000 | WO2000002918A1 Mouse growth hormone secretagogue receptor |