| Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210) |
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| 02/23/2000 | EP0980435A1 Human prohormone convertase 4 |
| 02/23/2000 | EP0980434A1 Intracellular production of hepatitis c e1 and e2 truncated polypeptides |
| 02/23/2000 | EP0980433A1 Uncoupling protein homologue: ucp 3 |
| 02/23/2000 | EP0980432A1 Chimeric opg polypeptides |
| 02/23/2000 | EP0980431A1 Antimicrobial peptide |
| 02/23/2000 | EP0980430A1 Recombinant fragments of the human acetylcholine receptor and their use for treatment of myasthenia gravis |
| 02/23/2000 | EP0980429A2 Human toll-like receptor proteins, related reagents and methods |
| 02/23/2000 | EP0980428A2 TECHNIQUES AND COMPOSITIONS FOR TREATING HEART FAILURE AND VENTRICULAR REMODELING BY $i(IN VIVO) DELIVERY OF ANGIOGENIC TRANSGENES |
| 02/23/2000 | EP0980427A1 Use of ulip proteins in the diagnosis and therapy of cancer and paraneoplastic neurological syndromes |
| 02/23/2000 | EP0980426A1 TYROSINE PHOSPHORYLATED CLEAVAGE FURROW-ASSOCIATED PROTEINS (PSTPIPs) |
| 02/23/2000 | EP0980425A2 A process for preparing an anti-oxidant |
| 02/23/2000 | EP0980424A2 Enzymatic nucleic acids: synthesis, selection and use |
| 02/23/2000 | EP0980390A2 Human-cd28 specific monoclonal antibodies for antigen non-specific activation of t-lymphocytes |
| 02/23/2000 | EP0980387A1 Prrsv antigenic sites identifying peptide sequences of prrs virus for use in vaccines or diagnostic assays |
| 02/23/2000 | EP0980379A2 Chimeric oligonucleotides and the use thereof |
| 02/23/2000 | EP0980378A1 Method for detecting the presence of biological matters of bovine origin, and oligonucleotides for its implementation |
| 02/23/2000 | EP0980263A1 Combined product associating a nucleic acid with a substance breaking up the extracellular matrix for gene therapy |
| 02/23/2000 | EP0980251A1 Tissue factor for influencing blood vessel formation |
| 02/23/2000 | EP0980204A1 76 kDa, 32 kDa, AND 50 kDa HELICOBACTER POLYPEPTIDES AND CORRESPONDING POLYNUCLEOTIDE MOLECULES |
| 02/23/2000 | EP0730663A4 Arrays of nucleic acid probes on biological chips |
| 02/23/2000 | CN1245537A Method for protecting plants |
| 02/23/2000 | CN1245536A Novel calpaines, production and use thereof |
| 02/23/2000 | CN1245535A Transgenic plants having increased starch content |
| 02/23/2000 | CN1245534A Mammalian cell surface antigens and relating reagents |
| 02/23/2000 | CN1245533A Mammalian chemokines |
| 02/23/2000 | CN1245532A Reduction of phosphorus containing components in edible oils comprising high amount of non-hydratable phosphorus by use of phospholipase from filamentous fungus having phospholipase A and/or B activit |
| 02/23/2000 | CN1245502A DNA encoding lepidopteran-active delta-endotoxins and its use |
| 02/23/2000 | CN1245393A Hypersensitive response induced resistance in plants by seed treatment |
| 02/23/2000 | CN1245011A Method for producing anti-pylorospirobacillus immune eggs |
| 02/23/2000 | CN1049686C Diagnostics and vaccines for hepatits virus non-A and non-B |
| 02/22/2000 | US6028250 For tissue-specific expression at site and stage for the reconstitution of plant cell wall xyloglucan; transgenic plants |
| 02/22/2000 | US6028249 DNA sequences which lead to the formation of levans, plasmids containing these sequences as well as a process for preparing transgenic plants |
| 02/22/2000 | US6028248 Plant fatty acid hydroxylase |
| 02/22/2000 | US6028247 Recombinant dna from safflower or brassica; for modification of fatty acid composition in plants |
| 02/22/2000 | US6028246 Transformed plant cell, comprising in its genome, a dna sequence encoding a crystal protein which is toxic to lepidoptera |
| 02/22/2000 | US6028245 Having murine double minute 2 gene inserted into genome and linked to promoter for expression in skin for phenotype resembling ichthyosis vulgaris; for screening treatments |
| 02/22/2000 | US6028244 Transgenic animal whose genome comprises a homozygous disruption an endogenous g protein gene; for screening agents |
| 02/22/2000 | US6028243 With reduced response to inteferon therapy after encephalomyocarditis infection; for screening viricides for ability to induce synthesis or activation of ribonuclease l |
| 02/22/2000 | US6028188 Synthetic oligomers having chirally pure phosphonate internucleosidyl linkages mixed with non-phosphonate internucleosidyl linkages |
| 02/22/2000 | US6028186 High affinity nucleic acid ligands of cytokines |
| 02/22/2000 | US6028184 For transgenic cells; for diagnosis of hypoglycemia, psychological and brain disorders; antidiabetic/hyperglycemic agents |
| 02/22/2000 | US6028182 Methylphosphonic acid esters, processes for their preparation, and their use |
| 02/22/2000 | US6028175 Amino acid sequence; for pharmacology and screening of agonists and antagonists |
| 02/22/2000 | US6028173 Amino acid sequence of polypeptide involved in axon outgrowth |
| 02/22/2000 | US6028169 Chemokine β-6 antagonists |
| 02/22/2000 | US6028049 Compositions comprising the Tbp2 subunit of the transferrin receptor of Neisseria meningitidis |
| 02/22/2000 | US6027945 Methods of isolating biological target materials using silica magnetic particles |
| 02/22/2000 | US6027935 Gene up-regulated in regenerating liver |
| 02/22/2000 | US6027934 Nucleic acid and vectors encoding an immunodominant fragment of a unique protein antigen originally derived from trypanosoma brucei rhodesiense organisms can induce immunoprotection such as against trypanosomes, leishmania |
| 02/22/2000 | US6027933 Surface expression libraries of heteromeric receptors |
| 02/22/2000 | US6027931 Adeno-associated virus (aav) helper functions that produce low amounts of the long form of aav rep (replication) proteins, resulting in high-efficiency production of recombinant aav |
| 02/22/2000 | US6027930 New mutant filamentous helper phage which has retained the gene iii promoter, whereas the gene iii encoding sequence is deleted; used for selection of specific binding proteins and their genes in phage display techniques |
| 02/22/2000 | US6027929 Method for cloning and producing the NspI restriction endonuclease in E. coli and purification of the recombinant NspI restriction endonuclease |
| 02/22/2000 | US6027927 Human trk receptors and neurotrophic factor inhibitors |
| 02/22/2000 | US6027925 Production of non-native bacterial exopolysaccharide in a recombinant bacterial host |
| 02/22/2000 | US6027924 Isolated nucleic acid molecule coding for tumor rejection antigen precursor MAGE-C1 and uses thereof |
| 02/22/2000 | US6027921 Chimeric proteins for use in transport of a selected substance into cells and DNA encoding chimeric proteins |
| 02/22/2000 | US6027920 System for protein expression and secretion especially in corynebacteria |
| 02/22/2000 | US6027919 BMP-12 and BMP-13 proteins and DNA encoding them |
| 02/22/2000 | US6027918 Dna molecule encoding a thermostable enzyme from the genus sulfolobus; vectors and transformed host cells; releases trehalose from nonreducing saccharides having trehalose as an end unit and a degree of glucose polymerization of at least 3 |
| 02/22/2000 | US6027917 Bone morphogenetic protein (BMP)-17 and BMP-18 compositions |
| 02/22/2000 | US6027915 Expression augmenting sequence elements (EASE) for eukaryotic expression systems |
| 02/22/2000 | US6027914 Cytokine response (cr) genes |
| 02/22/2000 | US6027913 Synthesizing a polypeptide encoded by a sequence of interest in vitro |
| 02/22/2000 | US6027912 Gene encoding an invertebrate alpha1 calcium channel subunit |
| 02/22/2000 | US6027910 Process for immobilizing enzymes to the cell wall of a microbial cell by producing a fusion protein |
| 02/22/2000 | US6027909 Bacillus strain and sporulation assay method |
| 02/22/2000 | US6027906 Dna molecules coding for the said penicillin binding protein (pbp) variants, as well as vectors containing them; assaying and designing therapeutically useful compounds which have high affinity to pbp |
| 02/22/2000 | US6027905 Methods for the detection of cervical cancer |
| 02/22/2000 | US6027900 Introducing dna into phaeodactylum tricornutum cells, wherein the dna contains a zeocin resistance determinant; and selecting for transformants in a culture medium containing salt to enhance growth, and zeocin or phleomycin |
| 02/22/2000 | US6027899 Determining the predisposition of a human subject to develop late-onset alzheimer's disease, by detecting the presence or absence of a gene for butyrylcholinesterase k varient, its presence indicates an increased propensity to alzheimer's |
| 02/22/2000 | US6027897 Promoter-primer mediated nucleic acid amplification |
| 02/22/2000 | US6027896 Providing a prognosis in subjects previously diagnosed with alzheimer's by identifying the apolipoprotein e type isoforms; then providing prognosis based on the presence or absence of an apolipoprotein e type 4 (apoe4) isoform |
| 02/22/2000 | US6027893 Two different nucleic acid analogues hybridizing to relatively short target sequences adjacently located on the nucleic acid to be identified; sensitive and specific determination |
| 02/22/2000 | US6027892 Compositions and methods for reducing radiation and drug resistance in cells |
| 02/22/2000 | US6027891 Method of early detection of HPV-associated carcinomas and extreme dysplasias caused by HPV |
| 02/22/2000 | US6027889 Coupling of the ligase detection reaction and the polymerase chain reaction permits multiplex detection of nucleic acid sequence differences |
| 02/22/2000 | US6027886 Sample containing rna is hybridized with probes complementary to the sequence to be determined carrying a detectable group; admixing with an agent which cleaves the single stranded polynucleotide and the probe is determined after transfer |
| 02/22/2000 | US6027885 Method for electrochemiluminescent labeling of nucleic acid, use in detection, and compositions therefor |
| 02/22/2000 | US6027884 Thermodynamics, design, and use of nucleic acid sequences |
| 02/22/2000 | US6027883 Optimal procedure for isolation of mutant mitochondrial alleles |
| 02/22/2000 | US6027882 Determining genetic predisposition for basal cell carcinoma by detecting a loss-of-function mutation in segment polarity genes; diagnosis of cancer |
| 02/22/2000 | US6027881 Mutant Aequorea victoria fluorescent proteins having increased cellular fluorescence |
| 02/22/2000 | US6027878 A nucleic acid sequence; diagnosis of helicobacter infections, ulcers and gastrointestinal disorders |
| 02/22/2000 | US6027877 Use of immobilized mismatch binding protein for detection of mutations and polymorphisms, purification of amplified DNA samples and allele identification |
| 02/22/2000 | US6027876 Method for monitoring pesticide resistance |
| 02/22/2000 | US6027875 Receptor infection assay |
| 02/22/2000 | US6027750 Systems and methods for the rapid isolation of nucleic acids |
| 02/22/2000 | US6027734 To provide protection against pneumococcal colonization and systemic infection, intranasally administering a composition consisting essentially of pneumococcal surface protein a or a fragment containing a protection-eliciting epitope |
| 02/22/2000 | US6027727 Inducing transient infertility in a mammal by administering a dose of recombinant zona pellicida proteins from a cat, cattle or cynomolgous monkey and human to stimulate antibody production; vaccines |
| 02/22/2000 | US6027722 Vectors for gene transfer |
| 02/22/2000 | US6027720 G-CSF conjugate |
| 02/22/2000 | US6027488 Flow-through electroporation system for ex vivo gene therapy |
| 02/22/2000 | CA2176713C Amphiphilic imidazolinium derivatives |
| 02/22/2000 | CA2091882C Gene therapy for cystic fibrosis |
| 02/22/2000 | CA2074214C Improvements in the in situ pcr |
| 02/22/2000 | CA2071630C Hybrid protein c |
| 02/22/2000 | CA1340910C Fibronectin binding protein |
| 02/22/2000 | CA1340908C Methods of producing secreted receptor analogs and biologically active peptide dimers |
| 02/22/2000 | CA1340906C Fibronectin binding protein as well as its preparation |