Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
05/2000
05/30/2000US6068995 Method for producing protein
05/30/2000US6068994 Expression of heterologous proteins in yeast using dna encoding a fusion protein of ubiquitin and the protein which is cleaved in vivo by an endogenous ubiquitin-specific hydrolase to yield protein with authentic n-terminal
05/30/2000US6068993 Vector for expression of heterologous protein and methods for extracting recombinant protein and for purifying isolated recombinant insulin
05/30/2000US6068992 Production of gonorrheal PI proteins and vaccines
05/30/2000US6068991 High expression Escherichia coli expression vector
05/30/2000US6068990 Proteins, their production and use
05/30/2000US6068984 Separating hb15 prositive cells from population of unrelated cells by reacting antibody that specifically binds the extracellular, transmembrane or cytoplasmic domain of the glycoprotein, then isolating cells
05/30/2000US6068983 Introducing into cells a dna molecule coding for an fc receptor which is then expressed for increased phagocytic activity; combating infection and/or modulating immune complex disease
05/30/2000US6068982 Ubiquitin conjugating enzymes
05/30/2000US6068980 Using nitrogen-containing silicone which is silica support grafted with at least one nitrogen-containing hydrocarbon radical as compaction agent; protection against deoxyribonucleases
05/30/2000US6068978 Apparatus and method for transfer of a fluid sample
05/30/2000US6068977 Constructing clone library and long-range probe library from nucleic acid sample, hybridizing labeled probes to library, detecting labels, recording signals, computerized data processing with calibration information to construct map
05/30/2000US6068976 Nucleotide sequences of control region of human obesity gene; for screening modulators of gene expression to treat hypertension, cardiovascular diseases, diabetes, infertility, obesity, anorexia, cachexia, and other eating disorders
05/30/2000US6068973 Suppressing transmission of influenza a virus to cell by contacting cell with influenza virus peptide of specific sequence chosen by a computer algorithm
05/30/2000US6068972 Screening by contacting microorganisms with organic solvent, determining expression of acr-like efflux pump gene locus, comparing to control, altered expression indicates activation of multiple antibiotic resistance phenotype
05/30/2000US6068912 Platible non-metallic filler material for metallurgical screening paste
05/30/2000US6068842 A polypeptide containing 66 kda protein of borrelia afzelli
05/30/2000US6068840 Recombinant CDR-grafted and chimeric anti-IL-8 antibodies containing CDRs or the variable region from the mouse monoclonal antibody, WS-4
05/30/2000US6068837 Mesothelial cell gene therapy
05/30/2000CA2676762A1 Peptides for the detection of hiv-1 group o
05/30/2000CA2181566C Compositions and methods using unbound mpl receptor for stimulating platelet production
05/30/2000CA2158274C Yeast cells engineered to produce pheromone system protein surrogates, and uses therefor
05/30/2000CA2142862C Method for inhibiting hiv replication using il-4
05/30/2000CA2119128C Alleviation of symptoms associated with inflammatory disease states
05/30/2000CA2100791C Method of directing biosynthesis of specific polyketides
05/30/2000CA2044630C Subtilisin mutants
05/30/2000CA2026570C Method for production and purification of hepatitis b vaccine
05/30/2000CA2019363C Dna and use thereof
05/26/2000CA2252967A1 Protein fragments for use in protein targeting
05/25/2000WO2000029846A2 COMPOSITIONS AND METHODS RELATING TO THE PEROXISOMAL PROLIFERATOR ACTIVATED RECEPTOR-α MEDIATED PATHWAY
05/25/2000WO2000029626A1 Rhadino virus lana acts in trans on a unit of rhadino virus dna to mediate efficient episome persistence
05/25/2000WO2000029623A2 Nucleic acids containing single nucleotide polymorphisms and methods of use thereof
05/25/2000WO2000029620A1 Methods of facilitating vascular growth
05/25/2000WO2000029618A1 Non-invasive detection of helicobacter pylori infection
05/25/2000WO2000029617A2 Water-soluble luminescent quantum dots and bioconjugates thereof
05/25/2000WO2000029616A1 Ligation assembly and detection of polynucleotides on solid-support
05/25/2000WO2000029615A2 A whole-genome radiation hybrid map of the dog genome and use thereof for identifying genes of interest
05/25/2000WO2000029614A1 Human prostaglandin receptors and methods of use thereof
05/25/2000WO2000029613A1 Method for the quantitative detection of nucleic acids
05/25/2000WO2000029611A2 Novel primers and probes for detecting hiv
05/25/2000WO2000029610A1 Analytical system based upon spore germination
05/25/2000WO2000029608A1 Transgenic animals as urinary bioreactors for the production of protein in the urine, recombinant dna construct for kidney-specific expression, and method of using same
05/25/2000WO2000029607A1 Novel enhancers of plant growth
05/25/2000WO2000029603A2 Low cost manufacture of oligosaccharides
05/25/2000WO2000029602A1 Transfection of male germ cells for generation of selectable transgenic stem cells
05/25/2000WO2000029601A1 A method for depopulating of vertebrate testis and for generation of transgenic species
05/25/2000WO2000029600A1 Systemic viral/ligand gene delivery system and gene therapy
05/25/2000WO2000029599A1 Viral vectors with late transgene expression
05/25/2000WO2000029598A1 Novel recombinant adenovirus
05/25/2000WO2000029597A2 Mutant genes encoding plant adp-glucose pyrophosphorylase and methods of use
05/25/2000WO2000029596A1 Phosphonate metabolizing plants
05/25/2000WO2000029595A1 Pad4 compositions and methods therefor
05/25/2000WO2000029594A1 Root-specific promoter
05/25/2000WO2000029593A1 Truncated nucleic acid sequences of the lettuce mosaic virus capsid gene and their use
05/25/2000WO2000029592A2 Chimeric promoters capable of mediating gene expression in plants upon pathogen infection and uses thereof
05/25/2000WO2000029591A1 Transgenic plant expressing maltogenic alpha-amylase
05/25/2000WO2000029590A1 Method for identifying inhibitors of ipc synthase
05/25/2000WO2000029588A1 Lysozyme fusion proteins in infections
05/25/2000WO2000029587A1 Thermostable xylanases
05/25/2000WO2000029586A2 Maize dna ligase i orthologue and uses thereof
05/25/2000WO2000029585A1 Gene coding for an acyltranferase of oil seed rape and uses thereof
05/25/2000WO2000029584A1 Antibody variants with higher binding affinity compared to parent antibodies
05/25/2000WO2000029583A2 Immunoglobulin superfamily proteins
05/25/2000WO2000029582A2 Cell surface receptor antigen vaccines
05/25/2000WO2000029581A1 Human tslp dna and polypeptides
05/25/2000WO2000029580A1 Calcium binding protein
05/25/2000WO2000029579A1 Mammalian chondromodulin-like protein
05/25/2000WO2000029578A1 Cloning and characterization of two m-rna transcription factors
05/25/2000WO2000029577A1 Novel members of the capsaicin/vanilloid receptor family of proteins and uses thereof
05/25/2000WO2000029576A1 Lipocalin homologs
05/25/2000WO2000029575A1 Novel human wnt gene
05/25/2000WO2000029574A2 Inflammation-associated genes
05/25/2000WO2000029573A2 Adenoviral vectors
05/25/2000WO2000029572A1 Proteins maguin
05/25/2000WO2000029571A1 Gene encoding novel transmembrane protein
05/25/2000WO2000029570A1 Novel protein and utilization thereof
05/25/2000WO2000029569A1 Methods of diagnosing or treating neurological diseases
05/25/2000WO2000029566A1 Promoters for gene expression in the roots of plants
05/25/2000WO2000029565A1 Methods for validating polypeptide targets that correlate to cellular phenotypes
05/25/2000WO2000029564A2 Human glycine transporter type 2
05/25/2000WO2000029563A1 Nucleic acid isolation
05/25/2000WO2000029562A1 Method of isolating plasmid dna
05/25/2000WO2000029561A2 Nucleotide construct with optimised codons for an hiv genetic vaccine based on a primary, early hiv isolate and synthetic envelope
05/25/2000WO2000029560A1 α-AMYLASE VARIANTS
05/25/2000WO2000029558A1 UDP-GALACTOSE: β-$I(N)-ACETYL-GLUCOSAMINE β1,3GALACTOSYLTRANSFERASES, β3GAL-T5
05/25/2000WO2000029557A1 A sensitive screening system for envelope-defective recombinant virus
05/25/2000WO2000029555A1 Methods using genetic package display for detecting and identifying protein-protein interactions
05/25/2000WO2000029553A1 Bioengineered tissue constructs and methods for producing and using them
05/25/2000WO2000029551A2 Cells, culture methods, and their use in autologous transplantation therapy
05/25/2000WO2000029550A2 Low oxygen culturing of central nervous system progenitor cells
05/25/2000WO2000029549A2 Low oxygen culturing of cells
05/25/2000WO2000029547A1 YfiI PSEUDOURIDINE SYNTHASE
05/25/2000WO2000029448A2 Human proteins having hydrophobic domains and dnas encoding these proteins
05/25/2000WO2000029447A1 Rhamm antagonist antibodies
05/25/2000WO2000029446A1 Method for inhibiting macrophage infiltration using monoclonal anti-alpha-d-antibodies
05/25/2000WO2000029445A1 Humanized antibody specific for human 4-1bb and pharmaceutical composition comprising same
05/25/2000WO2000029444A1 Generation of antibodies using polynucleotide vaccination in avian species
05/25/2000WO2000029443A1 Contraceptive antibody vaccines
05/25/2000WO2000029442A1 Method for producing antibodies acting against a polypeptide that only recognises the coding nucleic acid
05/25/2000WO2000029441A1 Novel g protein-coupled receptor protein, its dna and ligand thereof